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Top 24 Hotels In Murphysboro, Illinois 62966

Holiday Inn Express & Suites Murphysboro Carbondale an IHG Hotel

120 MUDDY MONSTER ROAD Murphysboro, IL

At Holiday Inn Express & Suites Murphysboro Carbondale an IHG Hotel, travelers to Murphysboro will find budget-friendly rooms with rates starting at $159.00, creating a clean, welcoming environment perfect for rest. Experience the festive atmosphere during the holidays at Holiday Inn Express, with special decorations and seasonal offerings.

With Murphysboro’s downtown just minutes away, Holiday Inn Express & Suites Murphysboro Carbondale an IHG Hotel makes it easy for guests to experience the best of the city without long commutes. Choose accommodations in Murphysboro that offer a great blend of value and comfort—book now!

  Call (855) 239-5277 to book with an agent.
  0.4 miles from Murphysboro, IL 62966

Starting at

$159.00

per night

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University Inn of Carbondale

2400 West Main St Carbondale, IL

With budget-friendly rooms from $80.00, University Inn of Carbondale provides inviting comfort for travelers bound for Murphysboro, creating a warm, inviting environment perfect for unwinding. Stay in rooms that are equipped with necessary amenities for a comfortable stay, ensuring cleanliness and convenience.

Guests at University Inn of Carbondale will love the calm atmosphere, with downtown Murphysboro just a drive away for easy access to the city’s top destinations. Experience Murphysboro with peace of mind, knowing your hotel delivers value—secure now!

  Call (855) 234-2997 to book with an agent.
  5.2 miles from Murphysboro, IL 62966

Starting at

$80.00

per night

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Home2 Suites by Hilton Carbondale

200 West Elm St Carbondale, IL

Enjoy the warm ambiance of Home2 Suites by Hilton Carbondale as you journey to Murphysboro, where quality accommodations provide comfort and relaxation, with rates beginning at $193.99. Experience the thoughtful design of Home2 Suites' suites, offering extra space and a sleeper sofa for guests or family.

With downtown Murphysboro still within easy reach, guests at Home2 Suites by Hilton Carbondale can explore the city’s top attractions before returning to a quieter retreat. Enjoy every aspect of your Murphysboro trip with a hotel that keeps you feeling at home—book today!

  Call (855) 235-6136 to book with an agent.
  7.0 miles from Murphysboro, IL 62966

Starting at

$193.99

per night

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Super 8 by Wyndham Carbondale

1180 East Main St Carbondale, IL

At Super 8 by Wyndham Carbondale, guests traveling to Murphysboro can enjoy budget-friendly rooms beginning at $85.00, providing a clean, welcoming environment ideal for relaxation. Appreciate the value of Super 8's amenities, including in-room coffee makers, to start your morning off on the right foot.

Guests at Super 8 by Wyndham Carbondale can enjoy being slightly removed from the city’s busiest areas, with downtown Murphysboro still within easy reach for all their sightseeing needs. Enjoy Murphysboro adventures with an affordable, inviting hotel—secure your stay today!

  Call (855) 234-5074 to book with an agent.
  8.0 miles from Murphysboro, IL 62966

Starting at

$85.00

per night

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Best Western Saluki Inn

801 North Giant City Rd Carbondale, IL

At Best Western Saluki Inn, travelers to Murphysboro will find budget-friendly rooms with rates beginning at $149.99, creating a welcoming and comfortable environment. Unwind in Best Western's beautifully designed outdoor spaces, ideal for enjoying the fresh air and scenic surroundings.

With downtown Murphysboro still within easy reach, guests at Best Western Saluki Inn can explore the city’s highlights while enjoying the hotel’s tranquil setting. Discover the smart way to stay in Murphysboro with inviting and affordable lodging—reserve now!

  Call (855) 234-7135 to book with an agent.
  8.4 miles from Murphysboro, IL 62966

Starting at

$149.99

per night

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Quality Inn Carbondale University area

1415 East Main St Carbondale, IL

Guests bound for Murphysboro will find harmonious accommodations at Quality Inn Carbondale University area, where rooms start at $89.99, creating a warm and inviting environment ideal for relaxation. Indulge in Quality Inn's fresh coffee available in the lobby, providing a warm welcome or a mid-day pick-me-up.

From Quality Inn Carbondale University area, guests can enjoy a quick drive into downtown Murphysboro, where they can explore the city’s highlights and return to a peaceful stay. Uncover an inviting and cost-effective hotel for your Murphysboro travels—secure today!

  Call (855) 239-5277 to book with an agent.
  8.4 miles from Murphysboro, IL 62966

Starting at

$89.99

per night

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Comfort Inn & Suites Carbondale University Area

2400 Reed Station Parkway Carbondale, IL

At Comfort Inn & Suites Carbondale University Area, travelers to Murphysboro will find plush, budget-friendly accommodations with rates from $136.99, creating a welcoming environment perfect for rest. Rest assured knowing that your safety and comfort are prioritized with top-notch security and cleanliness standards.

With Murphysboro a drive away, guests at Comfort Inn & Suites Carbondale University Area can explore the city’s highlights while enjoying the hotel’s quieter, more serene setting. Maximize your Murphysboro adventure with a hotel that offers unbeatable value—secure now!

  Call (855) 233-0132 to book with an agent.
  9.5 miles from Murphysboro, IL 62966

Starting at

$136.99

per night

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Walkers Bluff Casino Resort

777 Walkers Bluff Way Carterville, IL

Find a sanctuary of elegance at Walkers Bluff Casino Resort near Murphysboro, where sophisticated rooms blend comfort and style, with budget-friendly rates from $194.99. Experience the ultimate in sophisticated living in rooms that blend architectural elegance with contemporary luxuries.

Guests at Walkers Bluff Casino Resort can unwind in a tranquil setting, with the added benefit of downtown Murphysboro being a convenient drive away. Celebrate the splendor of Murphysboro with a hotel that offers a retreat like no other—reserve now!

  Call (855) 234-2997 to book with an agent.
  10.2 miles from Murphysboro, IL 62966

Starting at

$194.99

per night

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Fairgrounds Inn

1520 South Washington St Du Quoin, IL

With rates beginning at $99.99, Fairgrounds Inn is an ideal option for travelers visiting Murphysboro, offering homely rooms that provide a welcoming, comfortable experience. Relax in rooms that offer a straightforward approach to lodging, with all the necessary comforts for a budget-friendly trip.

The serene setting at Fairgrounds Inn makes for a peaceful stay, with downtown Murphysboro still close enough for guests to explore the city. Enjoy reliable comfort for your Murphysboro adventure—book your affordable room now!

  Call (855) 234-7135 to book with an agent.
  15.5 miles from Murphysboro, IL 62966

Starting at

$99.99

per night

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Super 8 by Wyndham Du Quoin

1010 South Jefferson Du Quoin, IL

Guests headed to Murphysboro can unwind in affordable comfort at Super 8 by Wyndham Du Quoin, with rooms beginning at $81.99, creating a harmonious and restful setting for all guests. Retreat to the cozy confines of Super 8's rooms, where modern amenities and homely comforts merge to create a restful haven.

Relax in the quiet surroundings of Super 8 by Wyndham Du Quoin, where peaceful surroundings offer a restful stay and downtown Murphysboro remains nearby. Book an inviting hotel that won’t strain your budget for your Murphysboro trip—secure today!

  Call (855) 233-0132 to book with an agent.
  16.7 miles from Murphysboro, IL 62966

Starting at

$81.99

per night

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Motel 6 Marion Il

8101 Express Dr. Marion, IL

Guests visiting Murphysboro can enjoy budget-conscious, well-maintained rooms at Motel 6 Marion Il, where rates start at $64.99, perfect for a hassle-free and comfortable stay. Take your pets along on your travels—Motel 6 offers pet-friendly rooms at no additional cost.

Guests can relax at Motel 6 Marion Il, where a peaceful atmosphere complements the convenience of nearby downtown Murphysboro. Make every dollar count on your Murphysboro adventure—book a budget hotel now!

  Call (855) 236-8982 to book with an agent.
  17.6 miles from Murphysboro, IL 62966

Starting at

$64.99

per night

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Comfort Inn & Suites Marion I-57

2403 Black Diamond Dr Marion, IL

With rates beginning at $137.75, Comfort Inn & Suites Marion I-57 provides budget-friendly accommodations for travelers visiting Murphysboro, creating a warm and inviting environment. Discover the modern amenities in select Comfort Inn renovations, offering an updated look while maintaining affordable rates.

For a relaxing stay, Comfort Inn & Suites Marion I-57 offers quiet surroundings while keeping downtown Murphysboro accessible for a day of sightseeing. Make your Murphysboro adventure exceptional without breaking the bank—secure your room today!

  Call (855) 239-5277 to book with an agent.
  19.9 miles from Murphysboro, IL 62966

Starting at

$137.75

per night

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Fairfield Inn&Suites by Marriott Marion

1400 Champions Drive Marion, IL

For an affordable stay near Murphysboro, Fairfield Inn&Suites by Marriott Marion offers inviting accommodations with rooms beginning at $154.99, creating a clean and comfortable space. Engage with local culture and community through Fairfield's thoughtful recommendations on area attractions and dining.

Relax at Fairfield Inn&Suites by Marriott Marion, where serene surroundings make for a peaceful stay and Murphysboro's activities are always close by. Plan your Murphysboro adventure with a hotel that’s as inviting as it is affordable—secure now!

  Call (855) 239-4019 to book with an agent.
  20.1 miles from Murphysboro, IL 62966

Starting at

$154.99

per night

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Country Inn & Suites by Radisson Marion IL

1306 Halfway Road Marion, IL

Guests visiting Murphysboro will appreciate the comfort at Country Inn & Suites by Radisson Marion IL, where rooms start at $152.99, creating a welcoming space perfect for relaxation and rest. Stay cozy by the fireplace in the lounge area at Country Inn & Suites, a perfect spot for chilly evenings.

Find your peaceful getaway at Country Inn & Suites by Radisson Marion IL, where you can unwind in quiet comfort while Murphysboro's attractions are never far away. Plan your Murphysboro visit with confidence, knowing your hotel has everything you need—lock in today!

  Call (855) 234-7135 to book with an agent.
  20.1 miles from Murphysboro, IL 62966

Starting at

$152.99

per night

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Super 8 by Wyndham Marion

2601 Vernell Rd Marion, IL

At Super 8 by Wyndham Marion, travelers to Murphysboro can find budget-conscious comfort with rooms beginning at $82.00, creating a intimate, comfortable environment for guests. Rest assured with Super 8's heightened cleanliness standards, offering a safe and spotless environment during your stay.

At Super 8 by Wyndham Marion, guests are treated to restful lodgings with the bonus of Murphysboro's top destinations only a short drive away. Enjoy reliable comfort for your Murphysboro adventure—book your affordable room now!

  Call (855) 235-0725 to book with an agent.
  20.2 miles from Murphysboro, IL 62966

Starting at

$82.00

per night

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Holiday Inn Express Hotel & Suites Marion Northeast an IHG Hotel

2609 Blue Heron Drive Marion, IL

With rooms beginning at $145.46, Holiday Inn Express Hotel & Suites Marion Northeast an IHG Hotel provides affordable accommodations for travelers visiting Murphysboro, creating a warm and welcoming environment for relaxation. Take advantage of the ice machines located on every floor for added convenience during your stay at Holiday Inn Express.

Settle into a peaceful retreat at Holiday Inn Express Hotel & Suites Marion Northeast an IHG Hotel, with easy access to Murphysboro for whenever you’re ready to explore. Choose a hotel that adds value to your Murphysboro journey—lock in your room now!

  Call (855) 235-6136 to book with an agent.
  20.3 miles from Murphysboro, IL 62966

Starting at

$145.46

per night

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Baymont by Wyndham Marion

2608 West Main St Marion, IL

For those visiting Murphysboro, Baymont by Wyndham Marion offers budget-friendly accommodations with rooms from $93.99, creating a comfortable, inviting atmosphere. Experience the local community with Baymont by Wyndham’s guided tours and recommendations for the best local attractions.

Find your peaceful getaway at Baymont by Wyndham Marion, where serene surroundings and quick access to Murphysboro ensure an enjoyable stay. Relax and recharge in Murphysboro with a hotel that doesn’t skimp on quality—book today!

  Call (855) 233-0132 to book with an agent.
  20.3 miles from Murphysboro, IL 62966

Starting at

$93.99

per night

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Quality Inn&Suites

2600 West Main St Marion, IL

At Quality Inn&Suites, guests visiting Murphysboro will find budget-friendly comfort with rooms from $89.99, creating a clean and inviting space perfect for rest. Unwind at the end of the day with Quality Inn's premium cable TV channels, a perfect way to relax in your room.

Discover a serene retreat at Quality Inn&Suites, offering guests a quiet escape with the convenience of Murphysboro's nearby attractions. Make Murphysboro travel both enjoyable and affordable with a practical hotel—secure now!

  Call (855) 235-6136 to book with an agent.
  20.4 miles from Murphysboro, IL 62966

Starting at

$89.99

per night

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Best Western Marion Hotel

400 Comfort Dr Marion, IL

At Best Western Marion Hotel, guests traveling to Murphysboro can enjoy budget-friendly rooms starting at $108.99, creating a warm and welcoming space perfect for unwinding. Savor the moment in Best Western's outdoor spaces, from gardens to patios, offering a serene setting to unwind.

Rest easy at Best Western Marion Hotel, a peaceful spot just outside Murphysboro, perfect for unwinding after a day of exploration. Take advantage of extra perks for your Murphysboro trip without the high cost—reserve now!

  Call (855) 235-0725 to book with an agent.
  20.4 miles from Murphysboro, IL 62966

Starting at

$108.99

per night

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Econo Lodge

1806 Bittle Place Marion, IL

For a quiet and affordable stay near Murphysboro, Econo Lodge offers budget-friendly rooms with rates from $61.99, creating a warm and welcoming atmosphere. Explore with confidence from Econo Lodge's convenient locations, perfect for guests looking to experience the local area without overspending.

Guests looking for a relaxing stay near Murphysboro will love the peaceful environment Econo Lodge offers. Book your Murphysboro stay and experience comfort without the expense—reserve today!

  Call (855) 234-5074 to book with an agent.
  20.9 miles from Murphysboro, IL 62966

Starting at

$61.99

per night

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Americas Best Value Inn Marion IL

1802 Bittle Pl Marion, IL

With rooms starting at $88.76, Americas Best Value Inn Marion IL offers inviting accommodations for travelers to Murphysboro, creating a charming and welcoming environment ideal for rest. Navigate your stay with Americas Best Value Inn's easy online booking, making planning your trip simple and straightforward.

Discover your peaceful retreat at Americas Best Value Inn Marion IL, just a drive away from the excitement of Murphysboro. Make your Murphysboro experience both cost-effective and comfortable—secure your stay today!

  Call (855) 233-0132 to book with an agent.
  21.0 miles from Murphysboro, IL 62966

Starting at

$88.76

per night

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Hotel 7 Inn Anna

100 Richview Dr Anna, IL

For a relaxing stay near Murphysboro, Hotel 7 Inn Anna offers comfy accommodations with rates beginning at $119.03, creating a warm, inviting atmosphere for rest. Relax in a space that blends affordability with a touch of luxury, providing a pleasant environment that exceeds expectations.

Unwind in style at Hotel 7 Inn Anna, where guests can enjoy the calm atmosphere and still explore Murphysboro at their leisure. Enjoy Murphysboro travel made easy with practical, well-equipped lodging—book now!

  Call (855) 239-5277 to book with an agent.
  21.6 miles from Murphysboro, IL 62966

Starting at

$119.03

per night

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Laketree Inn&Suites Marion

9600 Lake of Egypt Rd Marion, IL

For a comfortable stay near Murphysboro, Laketree Inn&Suites Marion offers budget-conscious accommodations with rates from $99.99, creating a warm and inviting atmosphere. Stay in a room that offers practical comfort and essential amenities, ensuring a pleasant and affordable visit.

Discover the tranquility of Laketree Inn&Suites Marion, offering a peaceful setting just a quick trip from the excitement of Murphysboro. Make your Murphysboro experience enjoyable without the high cost—reserve today!

  Call (855) 233-7850 to book with an agent.
  22.0 miles from Murphysboro, IL 62966

Starting at

$99.99

per night

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Americas Best Value Inn West Frankfort

1001 Factory Outlet Blvd West Frankfort, IL

For a comfortable and inviting stay, Americas Best Value Inn West Frankfort offers peaceful rooms with rates beginning at $72.99, creating a clean and comfortable space near Murphysboro. Experience the value of Americas Best Value Inn's complimentary services, including breakfast and Wi-Fi, enhancing your stay.

Found just outside of Murphysboro, Americas Best Value Inn West Frankfort provides the ideal base for exploring the area and returning to peaceful lodgings. Settle in and enjoy your Murphysboro stay with amenities that make all the difference—reserve now!

  Call (855) 233-0132 to book with an agent.
  22.7 miles from Murphysboro, IL 62966

Starting at

$72.99

per night

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