The best deals on hotels when visiting Depew in Ohio.

From game day to getaway, save even more on every hotel stay.

Save up to 70% when booking as a group. Select 9+ rooms to get started.

Top 24 Hotels In Depew, Ohio 45365

Hampton Inn Sidney

1600 Hampton Ct Sidney, OH

At Hampton Inn Sidney, travelers headed to Depew will find friendly comfort with rooms starting at $97.99, creating a warm and inviting environment ideal for relaxation. Grab a Hampton On the Run™ breakfast bag on weekdays, a quick and healthy option for guests who need to eat on the move.

At Hampton Inn Sidney, a quick drive delivers guests into the heart of downtown Depew, where the city’s most exciting attractions are always within easy reach. Discover the best value for your Depew stay with a hotel that won’t disappoint—reserve now!

  Call (855) 233-7850 to book with an agent.
  4.4 miles from Depew, OH 45365

Starting at

$97.99

per night

Read Reviews View Amenities View All Rooms

Quality Inn

1959 West Michigan Ave Sidney, OH

With budget-friendly rooms starting at $54.99, Quality Inn provides inviting accommodations for travelers to Depew, creating a warm-hearted environment. Experience the reliability of Quality Inn, with a commitment to providing clean and accommodating guest rooms.

Escape the city’s hustle and bustle at Quality Inn, a quiet retreat where the best of Depew is just a drive away. Enjoy your Depew adventure with lodging that makes every penny worth it—secure your room now!

  Call (855) 239-4019 to book with an agent.
  5.1 miles from Depew, OH 45365

Starting at

$54.99

per night

Read Reviews View Amenities View All Rooms

Motel 6 Sidney OH

2009 West Michigan St Sidney, OH

With budget-friendly rooms starting at $59.99, Motel 6 Sidney OH is a convenient option for travelers to Depew, creating a friendly and inviting space perfect for rest. Experience the warm, welcoming service at Motel 6, where guests are greeted with a smile and treated like family.

The calm setting of Motel 6 Sidney OH provides guests a retreat, with the vibrancy of downtown Depew still just a drive away for convenience. Choose value-driven comfort for your Depew visit—book your affordable stay today!

  Call (855) 234-5074 to book with an agent.
  5.2 miles from Depew, OH 45365

Starting at

$59.99

per night

Read Reviews View Amenities View All Rooms

Days Inn by Wyndham Sidney OH

400 Folkerth Avenue Sidney, OH

With rooms starting at $55.99, Days Inn by Wyndham Sidney OH offers inviting accommodations for guests bound for Depew, creating a clean, intimate atmosphere for unwinding. Take comfort in knowing our rooms offer modern conveniences and amenities, ensuring a pleasant and hassle-free stay.

The relaxing surroundings at Days Inn by Wyndham Sidney OH offer guests a quiet retreat, with downtown Depew just a convenient drive away for easy access. Make your Depew experience memorable and cost-effective—book your room now!

  Call (855) 239-4019 to book with an agent.
  5.3 miles from Depew, OH 45365

Starting at

$55.99

per night

Read Reviews View Amenities View All Rooms

TownePlace Suites by Marriott Sidney

420 Folkerth Ave Sidney, OH

Guests bound for Depew will find soothing comfort at TownePlace Suites by Marriott Sidney, with inviting rooms starting at $149.99, creating a warm and welcoming environment perfect for rest. Stay on top of your fitness goals with TownePlace Suites' outdoor exercise spaces and swimming pools, designed for an active lifestyle.

Guests staying at TownePlace Suites by Marriott Sidney can enjoy a peaceful stay while still having easy access to downtown Depew, where the city’s top attractions are just a drive away. Enjoy your Depew trip with accommodations that add value and comfort—book today!

  Call (855) 234-5074 to book with an agent.
  5.3 miles from Depew, OH 45365

Starting at

$149.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express & Suites Sidney an IHG Hotel

450 Folkerth Avenue Sidney, OH

For those visiting Depew, Holiday Inn Express & Suites Sidney an IHG Hotel offers relaxed accommodations with rates starting at $144.00, creating a clean, inviting space ideal for rest and comfort. Partake in Holiday Inn Express's commitment to a great start, ensuring every guest wakes up refreshed and ready for the day.

Guests staying at Holiday Inn Express & Suites Sidney an IHG Hotel will enjoy the quiet atmosphere, while downtown Depew is still just a drive away for a day of sightseeing and adventure. Enjoy your Depew adventure with lodging that makes every penny worth it—secure your room now!

  Call (855) 239-4019 to book with an agent.
  5.5 miles from Depew, OH 45365

Starting at

$144.00

per night

Read Reviews View Amenities View All Rooms

Baymont by Wyndham Piqua

950 East Ash Street Piqua, OH

Guests traveling to Depew will find budget-friendly comfort at Baymont by Wyndham Piqua, with inviting rooms starting at $74.00, creating a sheltered and welcoming space. Appreciate the convenience of having essential amenities on hand at Baymont by Wyndham, including ATMs and vending machines.

With downtown Depew a convenient drive away, guests at Baymont by Wyndham Piqua can balance the excitement of city exploration with the quiet atmosphere of the hotel. Rest assured your Depew trip will be memorable and budget-friendly—secure now!

  Call (855) 234-2997 to book with an agent.
  8.1 miles from Depew, OH 45365

Starting at

$74.00

per night

Read Reviews View Amenities View All Rooms

Comfort Inn & Suites Piqua Near Troy I75

987 East Ash St Piqua, OH

With rates beginning at $83.99, Comfort Inn & Suites Piqua Near Troy I75 provides budget-friendly accommodations for travelers visiting Depew, creating a warm and inviting environment. Navigate your trip with ease, thanks to Comfort Inn's central locations and accessibility to public transportation.

Staying at Comfort Inn & Suites Piqua Near Troy I75 allows guests to enjoy a more tranquil setting, while still being close enough to downtown Depew for a day of exploration. Make every moment in Depew count with a hotel that offers more for less—secure today!

  Call (855) 234-7135 to book with an agent.
  8.1 miles from Depew, OH 45365

Starting at

$83.99

per night

Read Reviews View Amenities View All Rooms

Comfort Suites Troy I75

1800 Towne Park Drive Troy, OH

With affordable rooms beginning at $98.99, Comfort Suites Troy I75 is a practical choice for guests visiting Depew, creating a clean and inviting space ideal for rest. Choose Comfort Suites for your next stay, where spacious suites, complimentary breakfast, and friendly service await at a great value.

At Comfort Suites Troy I75, guests can enjoy the quiet environment, with downtown Depew remaining nearby for all their city adventures. Make your Depew trip memorable with a hotel that offers more for less—secure your stay now!

  Call (855) 235-6136 to book with an agent.
  13.6 miles from Depew, OH 45365

Starting at

$98.99

per night

Read Reviews View Amenities View All Rooms

Home2 Suites Troy

1805 Towne Park Dr. Troy, OH

Home2 Suites Troy offers a relaxing option for travelers visiting Depew, with comfortable accommodations starting at a welcoming $121.99 per night. Benefit from Home2 Suites' Hilton CleanStay program, ensuring a higher standard of cleanliness throughout your stay.

Guests staying at Home2 Suites Troy will enjoy the tranquil surroundings, while downtown Depew remains easily accessible by car. Maximize your time in Depew with accommodations that are both practical and elegant—secure now!

  Call (855) 236-8982 to book with an agent.
  13.7 miles from Depew, OH 45365

Starting at

$121.99

per night

Read Reviews View Amenities View All Rooms

Super 9 Motel

30 Troy Town Drive Troy, OH

For those visiting Depew, Super 9 Motel offers affordable comfort with rooms starting at $65.00, creating a restful, inviting space ideal for guests seeking relaxation. Find a welcoming retreat in our rooms, where essential comforts and thoughtful service combine to offer a budget-conscious solution.

Enjoy a restful stay at Super 9 Motel, where peaceful surroundings meet easy access to downtown Depew for exploration. Stay comfortably and affordably in Depew with value-driven accommodations—book today!

  Call (855) 235-6136 to book with an agent.
  14.0 miles from Depew, OH 45365

Starting at

$65.00

per night

Read Reviews View Amenities View All Rooms

Hampton Inn Troy

45 Troy Town Dr Troy, OH

For budget-savvy travelers headed to Depew, Hampton Inn Troy offers easygoing comfort with rooms starting at $93.99, creating a clean, inviting environment. Adjust your room’s climate to your preference with Hampton’s individual air conditioning units, ensuring comfort in any weather.

At Hampton Inn Troy, guests can unwind in a serene environment, knowing that downtown Depew is just a comfortable drive away. Enjoy a worry-free Depew adventure with budget-conscious, well-equipped lodging—book today!

  Call (855) 239-5277 to book with an agent.
  14.0 miles from Depew, OH 45365

Starting at

$93.99

per night

Read Reviews View Amenities View All Rooms

Fairfield Inn & Suites Dayton Troy

83 Troy Town Center Dr Troy, OH

For budget-savvy travelers, Fairfield Inn & Suites Dayton Troy provides friendly accommodations with rates beginning at $109.99, creating a clean and comfortable space near Depew. Enjoy Fairfield’s seasonal outdoor equipment rentals, such as bicycles in the summer and snow gear in the winter.

Guests at Fairfield Inn & Suites Dayton Troy can enjoy the calm environment, with downtown Depew still accessible for all their city adventures. Unwind in Depew with budget-friendly accommodations that don’t skimp on comfort—book now!

  Call (855) 233-7850 to book with an agent.
  14.0 miles from Depew, OH 45365

Starting at

$109.99

per night

Read Reviews View Amenities View All Rooms

Residence Inn by Marriott Dayton Troy

87 Troy Town Dr Troy, OH

Find a mellifluous escape at Residence Inn by Marriott Dayton Troy near Depew, where restful accommodations create a relaxing stay, with inviting rates beginning at just $119.00. Experience the convenience and comfort of Residence Inn, where you can enjoy a hassle-free stay from check-in to checkout.

Guests can enjoy the quiet of Residence Inn by Marriott Dayton Troy, while downtown Depew remains a short drive away for all their sightseeing needs. Relax in Depew with accommodations that turn your trip into a memorable getaway—secure now!

  Call (855) 239-5277 to book with an agent.
  14.0 miles from Depew, OH 45365

Starting at

$119.00

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express & Suites Troy an IHG Hotel

60 Troy Town Dr Troy, OH

Find a intimate getaway at Holiday Inn Express & Suites Troy an IHG Hotel as you visit Depew, where inviting rooms offer comfort and quality, with rates starting from an accessible $117.75. Relax in the contemporary comfort of Holiday Inn Express's lobby areas, featuring sleek furnishings and inviting spaces for guests to gather.

For a restful stay, Holiday Inn Express & Suites Troy an IHG Hotel provides peaceful surroundings, with downtown Depew still a comfortable drive away. Unwind in Depew with a hotel that combines elegance and budget-friendly rates—lock in today!

  Call (855) 234-5074 to book with an agent.
  14.1 miles from Depew, OH 45365

Starting at

$117.75

per night

Read Reviews View Amenities View All Rooms

Motel 6 Troy OH

1260 South Dorset Rd Troy, OH

At Motel 6 Troy OH, travelers bound for Depew can relax in inviting accommodations with rooms from $62.99, creating a reassuring and comfortable atmosphere. Enjoy the bright, cheerful colors and decor of Motel 6's interiors, designed to make your stay a little brighter.

For travelers who value both peace and proximity, Motel 6 Troy OH offers quiet accommodations with easy access to downtown Depew. Plan a practical, budget-friendly stay for your Depew travels—book today!

  Call (855) 239-4019 to book with an agent.
  15.4 miles from Depew, OH 45365

Starting at

$62.99

per night

Read Reviews View Amenities View All Rooms

Budget Inn Troy

1330 Archer Dr Troy, OH

With budget-conscious rooms starting at $53.10, Budget Inn Troy provides affordable comfort for guests visiting Depew, creating a clean and snug environment for rest. Find a comfortable retreat in our rooms, where basic amenities and attentive service create a value-driven experience.

Rest easy at Budget Inn Troy, where peaceful surroundings create a restful stay and downtown Depew is still nearby. Plan ahead and stay affordably while exploring Depew—reserve your hotel now!

  Call (855) 234-5074 to book with an agent.
  15.4 miles from Depew, OH 45365

Starting at

$53.10

per night

Read Reviews View Amenities View All Rooms

Comfort Inn & Suites Tipp City Dayton North I-75

19 Weller Drive Tipp City, OH

With affordable rooms starting at $97.00, Comfort Inn & Suites Tipp City Dayton North I-75 provides quiet accommodations for travelers bound for Depew, creating a clean, inviting space. Experience local culture with our guide to nearby attractions, enhancing your stay with rich experiences and adventures.

Guests staying at Comfort Inn & Suites Tipp City Dayton North I-75 will appreciate the peaceful atmosphere, while downtown Depew remains accessible for a day of city exploration. Find out how affordable and enjoyable your Depew visit can be—reserve your room now!

  Call (855) 233-0132 to book with an agent.
  19.1 miles from Depew, OH 45365

Starting at

$97.00

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express Hotels&Suites Dayton North Tipp City an IHG Hotel

1100 West Main St Tipp City, OH

Guests headed to Depew can enjoy affordable comfort at Holiday Inn Express Hotels&Suites Dayton North Tipp City an IHG Hotel, with rooms starting at $114.00, providing a alluring space perfect for relaxation. Appreciate the speed and convenience of Holiday Inn Express's digital check-out process, available via the app or in-room TV.

Unwind at Holiday Inn Express Hotels&Suites Dayton North Tipp City an IHG Hotel in a quiet setting, where downtown Depew is still within easy reach for a day of adventure. Make Depew travel effortless and affordable with inviting accommodations—secure today!

  Call (855) 235-6136 to book with an agent.
  19.2 miles from Depew, OH 45365

Starting at

$114.00

per night

Read Reviews View Amenities View All Rooms

Hotel Versailles

21 West Main St Versailles, OH

For an affordable and welcoming stay near Depew, Hotel Versailles offers budget-friendly rooms with rates from $259.99, creating a clean and comfortable atmosphere. Experience a more satisfying visit in accommodations that offer additional amenities and enhanced comfort.

A relaxing stay awaits at Hotel Versailles, where serene surroundings provide a restful atmosphere and downtown Depew remains accessible. Choose a hotel that makes Depew travel simple and relaxing—lock in your stay today!

  Call (855) 235-0725 to book with an agent.
  19.5 miles from Depew, OH 45365

Starting at

$259.99

per night

Read Reviews View Amenities View All Rooms

Cobblestone Hotel & Suites Urbana

170 State Route 55 Urbana, OH

For a relaxing stay near Depew, Cobblestone Hotel & Suites Urbana offers snug accommodations with rates beginning at $127.99, creating a warm, inviting atmosphere for rest. Enjoy accommodations that focus on essential comforts, with rooms that offer clean bedding, private bathrooms, and a quiet atmosphere.

Unwind at Cobblestone Hotel & Suites Urbana, a tranquil retreat that provides easy access to the many attractions of Depew. Treat yourself to a memorable Depew trip with well-equipped, cost-friendly accommodations—reserve today!

  Call (855) 233-0132 to book with an agent.
  21.3 miles from Depew, OH 45365

Starting at

$127.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Bellefontaine

1117 North Main Street Bellefontaine, OH

Guests visiting Depew can enjoy the affordable comfort at Super 8 by Wyndham Bellefontaine, where comforting rooms start at $87.99, creating a warm and inviting environment. Welcome to a world of convenience and comfort at Super 8 by Wyndham, where every stay promises value and satisfaction.

At Super 8 by Wyndham Bellefontaine, you’ll find restful accommodations and the convenience of being close to Depew's most exciting destinations. Plan your Depew getaway with a budget-friendly hotel that delivers comfort—reserve now!

  Call (855) 239-4019 to book with an agent.
  21.4 miles from Depew, OH 45365

Starting at

$87.99

per night

Read Reviews View Amenities View All Rooms

Comfort Inn

260 Northview Dr Bellefontaine, OH

Guests bound for Depew will find inviting comfort at Comfort Inn, where budget-friendly rooms start at $94.99, creating a clean and welcoming environment. Feel welcomed and cared for by our dedicated team, who go above and beyond to create a memorable experience.

Escape the everyday rush at Comfort Inn, a restful getaway where Depew's attractions are always within easy reach. Find your ideal Depew hotel with amenities that make your visit extra special—lock in today!

  Call (855) 233-7850 to book with an agent.
  21.7 miles from Depew, OH 45365

Starting at

$94.99

per night

Read Reviews View Amenities View All Rooms

Best Western Wapakoneta Inn

1008 Lunar Drive Wapakoneta, OH

With budget-friendly rooms from $112.99, Best Western Wapakoneta Inn provides intimate-feeling accommodations for travelers bound for Depew, creating a warm, welcoming space. Maintain your health routine in Best Western's fully equipped fitness centers, designed to cater to all levels of exercise.

Find your quiet escape at Best Western Wapakoneta Inn, situated conveniently for exploring the vibrant attractions of Depew just a short drive away. Enjoy the best of Depew with accommodations that enhance your travel experience—reserve now!

  Call (855) 234-7135 to book with an agent.
  22.6 miles from Depew, OH 45365

Starting at

$112.99

per night

Read Reviews View Amenities View All Rooms