The best deals on hotels when visiting Guam in Missouri.

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Top 24 Hotels In Guam, Missouri 63846

Econo Lodge Dexter

913 Outer Rd Dexter, MO

With budget-friendly rooms starting at $64.99, Econo Lodge Dexter is a practical choice for travelers bound for Guam, providing a easygoing, welcoming atmosphere perfect for rest. Appreciate the straightforward accommodations at Econo Lodge, focusing on the necessities to ensure a quality stay.

A quiet retreat awaits travelers at Econo Lodge Dexter, with downtown Guam still a short drive away for easy access to city adventures. Make the most of your Guam experience with affordable, welcoming lodging—book now!

  Call (855) 234-5074 to book with an agent.
  10.4 miles from Guam, MO 63846

Starting at

$64.99

per night

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Travelodge by Wyndham Dexter

1608 East Business US 60 Dexter, MO

With rooms starting at $80.99, Travelodge by Wyndham Dexter provides inviting accommodations for guests visiting Guam, creating a warm and welcoming environment ideal for rest. Experience a warm welcome at Travelodge, where the staff’s commitment to excellent service begins the moment you arrive.

Unwind in the calm atmosphere of Travelodge by Wyndham Dexter, where quiet surroundings create a relaxing stay, and downtown Guam is still nearby. Choose a hotel that offers comfort and savings for your Guam adventure—book today!

  Call (855) 236-8982 to book with an agent.
  11.1 miles from Guam, MO 63846

Starting at

$80.99

per night

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Hickory House Inn

1802 North Outer Rd Dexter, MO

At Hickory House Inn, travelers to Guam will find budget-friendly comfort with rooms beginning at $54.99, creating a clean and inviting environment. Find a straightforward stay in rooms that focus on essential comforts, offering a clean and efficient environment.

For a quiet retreat, Hickory House Inn offers peaceful surroundings, with the convenience of downtown Guam remaining nearby for city access. Discover how great your Guam stay can be with thoughtful, cost-effective amenities—secure now!

  Call (855) 235-6136 to book with an agent.
  11.3 miles from Guam, MO 63846

Starting at

$54.99

per night

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Dexter Inn

1807 West Business US Highway 60 Dexter, MO

With rooms starting at $62.99, Dexter Inn provides budget-conscious comfort for travelers visiting Guam, creating a welcoming, inviting space for relaxation. Experience rooms that provide a touch more luxury and comfort, making your stay relaxing and enjoyable at a great value.

Guests staying at Dexter Inn will enjoy a peaceful atmosphere, with downtown Guam remaining nearby for exploration. Enjoy peace of mind on your Guam trip with accommodations designed for relaxation—book today!

  Call (855) 236-8982 to book with an agent.
  11.4 miles from Guam, MO 63846

Starting at

$62.99

per night

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Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel

115 Hospitality Dr Sikeston, MO

At Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel, travelers bound for Guam will find budget-conscious comfort with rates starting at $129.00, creating a clean and welcoming environment. Discover the efficiency of Holiday Inn Express's self-service check-in kiosks, designed for quick arrivals and departures.

For those looking to unwind, Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel offers a quiet retreat, while the convenience of downtown Guam is within reach. Discover a welcoming, cost-effective hotel perfect for your Guam getaway—secure today!

  Call (855) 233-0132 to book with an agent.
  13.7 miles from Guam, MO 63846

Starting at

$129.00

per night

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Hampton Inn Sikeston

1240 Commerce Drive Sikeston, MO

For an affordable and inviting stay, Hampton Inn Sikeston offers warm rooms with rates beginning at $112.99, creating a clean and comfortable atmosphere near Guam. Refresh and rejuvenate in Hampton's stylish bathrooms, equipped with modern fixtures and invigorating shower facilities.

At Hampton Inn Sikeston, guests can embrace the calm surroundings, with downtown Guam still reachable by a simple drive for a day of fun. Make every day in Guam a pleasure with a hotel that goes above and beyond—secure now!

  Call (855) 235-0725 to book with an agent.
  13.8 miles from Guam, MO 63846

Starting at

$112.99

per night

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Super 8 by Wyndham Sikeston / Miner Area

2609 East Malone Ave Sikeston, MO

Guests bound for Guam can find budget-friendly comfort at Super 8 by Wyndham Sikeston / Miner Area, where rooms begin at $60.00, creating a clean, welcoming environment perfect for rest. Stay refreshed with Super 8's available laundry facilities, a convenient option for travelers on extended trips.

The peaceful setting at Super 8 by Wyndham Sikeston / Miner Area is perfect for those who prefer to escape the city’s bustle, yet downtown Guam is still within reach. Plan your Guam trip with a welcoming, budget-friendly hotel—reserve your room today!

  Call (855) 239-5277 to book with an agent.
  15.7 miles from Guam, MO 63846

Starting at

$60.00

per night

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Comfort Inn & Suites Sikeston I-55

109 Matthews Ln Sikeston, MO

For a restful stay, Comfort Inn & Suites Sikeston I-55 offers inviting accommodations with rooms starting at $87.99, creating a clean, welcoming environment perfect for travelers. Keep cool and comfortable year-round with air-conditioned rooms, ensuring a pleasant stay regardless of the weather.

At Comfort Inn & Suites Sikeston I-55, the quiet atmosphere offers a restful stay, with the added convenience of downtown Guam being nearby for sightseeing. Discover a hotel that makes your Guam adventure stress-free and enjoyable—reserve today!

  Call (855) 239-5277 to book with an agent.
  15.9 miles from Guam, MO 63846

Starting at

$87.99

per night

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Travel Inn & Suites Sikeston / Miner (i-55 Exit 67)

100 Matthews Lane Sikeston, MO

Guests traveling to Guam will find restful accommodations at Travel Inn & Suites Sikeston / Miner (i-55 Exit 67), with rooms starting at $62.99, creating a warm and welcoming atmosphere. Experience a touch of extra comfort in rooms that offer upgraded amenities for a more enjoyable and cost-effective stay.

At Travel Inn & Suites Sikeston / Miner (i-55 Exit 67), guests can unwind in quiet surroundings, with the added convenience of downtown Guam being just a drive away. Relax in a hotel that makes your Guam adventure feel special and stress-free—reserve now!

  Call (855) 233-7850 to book with an agent.
  15.9 miles from Guam, MO 63846

Starting at

$62.99

per night

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Best Western Plus Sikeston

120 South Interstate Drive Sikeston, MO

At Best Western Plus Sikeston, travelers visiting Guam can enjoy inviting accommodations with rooms starting at $76.99, creating a warm, welcoming environment for rest. Experience the local vibe with Best Western Plus' themed décor, reflecting the culture and style of the surrounding area.

For those seeking quiet, Best Western Plus Sikeston offers a serene retreat while keeping downtown Guam easily accessible for city exploration. Discover Guam with a hotel designed for relaxation and savings—lock in today!

  Call (855) 239-5277 to book with an agent.
  16.2 miles from Guam, MO 63846

Starting at

$76.99

per night

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Days Inn&Suites by Wyndham Sikeston

220 South Interstate Dr Sikeston, MO

Guests visiting Guam will appreciate the peaceful comfort at Days Inn&Suites by Wyndham Sikeston, where budget-friendly rooms start at $64.99, creating a warm and inviting space. Unwind with Days Inn's in-room entertainment options, including cable TV and streaming capabilities for a cozy night in.

Travelers staying at Days Inn&Suites by Wyndham Sikeston can unwind in serene surroundings, while downtown Guam remains close enough for city adventures. Stay comfortable and save big on your Guam visit—lock in your room today!

  Call (855) 234-5074 to book with an agent.
  16.2 miles from Guam, MO 63846

Starting at

$64.99

per night

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Country Yard Inn&Suite

110 South Interstate Drive Sikeston, MO

With rooms beginning at $54.99, Country Yard Inn&Suite provides affordable accommodations for guests headed to Guam, creating a secure and comfortable space perfect for relaxation. Relax in accommodations that deliver standard amenities, offering a comfortable environment at a budget-friendly price.

At Country Yard Inn&Suite, guests can relax in serene surroundings, with the energy of downtown Guam still accessible by car for a day of exploration. Stay smart and keep your Guam travel budget intact—reserve your hotel now!

  Call (855) 234-5074 to book with an agent.
  16.2 miles from Guam, MO 63846

Starting at

$54.99

per night

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Quality Inn Charleston Sikeston

102 Drake St Charleston, MO

Guests traveling to Guam will appreciate the inviting comfort at Quality Inn Charleston Sikeston, where calm rooms start at $66.99, creating a welcoming space for rest. Appreciate Quality Inn's commitment to accessibility, offering rooms and facilities designed for guests with disabilities.

Experience a refreshing stay at Quality Inn Charleston Sikeston, with both spacious accommodations and convenient access to Guam. Take the guesswork out of Guam travel with a hotel that delivers on value—lock in today!

  Call (855) 239-5277 to book with an agent.
  26.1 miles from Guam, MO 63846

Starting at

$66.99

per night

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Super 8 by Wyndham Charleston / Sikeston East MO

310 South Story St Charleston, MO

Guests bound for Guam will find soft accommodations at Super 8 by Wyndham Charleston / Sikeston East MO, with rooms starting at $57.99, creating a warm and inviting atmosphere perfect for a peaceful stay. Utilize the ample parking offered by Super 8, providing peace of mind for those traveling with personal or rental vehicles.

Escape the crowds at Super 8 by Wyndham Charleston / Sikeston East MO, where guests can relax in quiet comfort with Guam's highlights just a short drive away. Make the most of your Guam trip with practical, budget-friendly lodging—book today!

  Call (855) 236-8982 to book with an agent.
  27.6 miles from Guam, MO 63846

Starting at

$57.99

per night

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Eagle Inn Charleston

2811 East Marshall Street Charleston, MO

At Eagle Inn Charleston, travelers to Guam will find inviting accommodations with rooms beginning at $69.29, creating a welcoming, welcoming environment for relaxation. Experience dependable comfort in rooms that offer practical amenities, ensuring a pleasant and budget-friendly stay.

At Eagle Inn Charleston, the peaceful surroundings create a relaxing atmosphere, while Guam remains just a short drive away. Enjoy Guam to the fullest with a hotel that prioritizes comfort and value—book now!

  Call (855) 239-5277 to book with an agent.
  28.5 miles from Guam, MO 63846

Starting at

$69.29

per night

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EC Reeds Mercantile&Hotel

301 1st St Marble Hill, MO

Find relaxation and value at EC Reeds Mercantile&Hotel as you journey to Guam, where quality rooms provide a cozy-like atmosphere, with inviting rates beginning at $116.99. Find a welcoming atmosphere in accommodations that provide additional comfort and amenities, ensuring a pleasant visit.

Discover a calm haven at EC Reeds Mercantile&Hotel, where guests can rest comfortably with Guam's best spots within easy reach. Relax in Guam with a hotel that elevates your stay with added conveniences—secure now!

  Call (855) 234-2997 to book with an agent.
  28.7 miles from Guam, MO 63846

Starting at

$116.99

per night

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Travel Inn

301 Route Ad Marston, MO

Guests bound for Guam will appreciate the budget-conscious comfort at Travel Inn, with easygoing rooms starting at $60.96, creating a warm, inviting atmosphere. Relax in a space that blends affordability with a touch of luxury, providing a pleasant environment that exceeds expectations.

Relax in comfort at Travel Inn, a perfect spot for unwinding while Guam remains within easy reach. Embrace the best of Guam with a welcoming, cost-effective hotel—book your stay today!

  Call (855) 234-5074 to book with an agent.
  28.9 miles from Guam, MO 63846

Starting at

$60.96

per night

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Candlewood Suites Cape Girardeau an IHG Hotel

485 South Mount Auburn Rd Cape Girardeau, MO

For a restful stay, Candlewood Suites Cape Girardeau an IHG Hotel offers friendly accommodations with rates from $101.92, creating a welcoming space ideal for travelers visiting Guam. Experience the welcoming atmosphere of Candlewood Suites, where guest comfort is the top priority.

Found just beyond the city, Candlewood Suites Cape Girardeau an IHG Hotel offers a peaceful retreat that’s never too far from Guam's lively attractions. Relax and explore Guam with a hotel that keeps your expenses low and spirits high—reserve now!

  Call (855) 234-5074 to book with an agent.
  30.1 miles from Guam, MO 63846

Starting at

$101.92

per night

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Fairfield Inn & Suites by Marriott Cape Girardeau

433 CAPE WEST CROSSINGS Cape Girardeau, MO

At Fairfield Inn & Suites by Marriott Cape Girardeau, travelers visiting Guam can enjoy snug accommodations with rooms from $124.99, creating a warm, inviting space perfect for relaxation. Experience the festive spirit of Fairfield during the holidays, with special decorations, events, and treats to celebrate the season.

Enjoy a restful stay at Fairfield Inn & Suites by Marriott Cape Girardeau, where calm lodgings provide a peaceful atmosphere close to Guam's offerings. Stay smart and relaxed in Guam with value-driven amenities—book your room now!

  Call (855) 234-5074 to book with an agent.
  30.1 miles from Guam, MO 63846

Starting at

$124.99

per night

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Hampton Inn Cape Girardeau I 55 East

207 South Mt. Auburn Rd Cape Girardeau, MO

With affordable rooms beginning at $113.99, Hampton Inn Cape Girardeau I 55 East provides inviting accommodations for guests visiting Guam, creating a warm, comfortable space. Appreciate the small comforts in Hampton’s rooms, such as ample charging ports and high-quality toiletries, enhancing your stay.

Stay at Hampton Inn Cape Girardeau I 55 East to experience the perfect blend of quiet and convenience, with restful accommodations just minutes from Guam. Make your Guam trip memorable with a hotel that offers more for less—secure your stay now!

  Call (855) 233-0132 to book with an agent.
  30.4 miles from Guam, MO 63846

Starting at

$113.99

per night

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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel

3253 William Street Cape Girardeau, MO

For an affordable and sheltered stay, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel offers inviting rooms with rates beginning at $124.00, creating a welcoming and comfortable space for guests. Experience the personalized service of Holiday Inn Express's concierge, available to help tailor your stay to your preferences.

Stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel for a quiet and restful experience, while keeping the lively streets of Guam close for your adventures. Enjoy your Guam visit to the fullest with a hotel that delivers cost-effective comfort—secure now!

  Call (855) 233-7850 to book with an agent.
  30.7 miles from Guam, MO 63846

Starting at

$124.00

per night

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Town House Inn Cape Giradreau

505 North Kingshighway Street Cape Girardeau, MO

At Town House Inn Cape Giradreau, travelers bound for Guam will find intimate-feeling rooms with rates beginning at $55.00, creating a warm and welcoming space ideal for relaxation. Experience functional lodging, where rooms are designed to be both comfortable and economical, catering to practical travelers.

Stay at Town House Inn Cape Giradreau for a relaxing retreat, where a calm atmosphere and the convenience of Guam make for the perfect trip. Enjoy your Guam adventure with lodging that makes every penny worth it—secure your room now!

  Call (855) 239-4019 to book with an agent.
  32.1 miles from Guam, MO 63846

Starting at

$55.00

per night

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Courtyard by Marriott Cape Girardeau Downtown

400 Broadway St. Cape Girardeau, MO

Enjoy the warm ambiance of Courtyard by Marriott Cape Girardeau Downtown when visiting Guam, where quality accommodations provide relaxation, with nightly rates beginning at $149.99. Taste the local flavors at Courtyard's Bistro, offering menus inspired by regional traditions and designed to satisfy every palate.

Unwind in comfort at Courtyard by Marriott Cape Girardeau Downtown, where peaceful accommodations ensure a relaxing stay with Guam within reach. Enjoy added perks and peace of mind during your Guam stay—secure your hotel room now!

  Call (855) 239-4019 to book with an agent.
  32.5 miles from Guam, MO 63846

Starting at

$149.99

per night

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Rockwood Inn

603 Henderson Ave Cape Girardeau, MO

At Rockwood Inn, guests visiting Guam can enjoy reassuring, affordable rooms starting at $151.99, creating a clean and inviting environment for a peaceful stay. Enjoy practical comfort in rooms that deliver essential amenities, ensuring a comfortable stay without the extra cost.

Find your perfect retreat at Rockwood Inn, where the quiet atmosphere lets you unwind while Guam remains just a drive away. Stay affordably and experience the best of Guam with comfort—reserve now!

  Call (855) 233-0132 to book with an agent.
  32.6 miles from Guam, MO 63846

Starting at

$151.99

per night

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