The best deals on hotels when visiting Samos in Missouri.

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Top 24 Hotels In Samos, Missouri 63834

Eagle Inn Charleston

2811 East Marshall Street Charleston, MO

At Eagle Inn Charleston, travelers to Samos can enjoy cozy-like, affordable rooms with rates starting at $69.29, creating a warm and welcoming space ideal for relaxation. Enjoy the essentials in well-maintained rooms that provide a comfortable and affordable environment for your visit.

At Eagle Inn Charleston, a quick drive takes guests into downtown Samos, where the city’s most popular destinations are easily accessible. Stay affordably while enjoying extra amenities on your Samos adventure—lock in now!

  Call (855) 239-4019 to book with an agent.
  4.1 miles from Samos, MO 63834

Starting at

$69.29

per night

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Super 8 by Wyndham Charleston / Sikeston East MO

310 South Story St Charleston, MO

For a comfortable and budget-friendly stay, Super 8 by Wyndham Charleston / Sikeston East MO offers warm rooms with rates from $60.99, creating a welcoming, clean environment near Samos. Depend on Super 8 for a stay that combines convenience, comfort, and cost-effectiveness, ideal for savvy travelers.

From Super 8 by Wyndham Charleston / Sikeston East MO, a short drive takes guests right into the bustling downtown area of Samos, offering easy access to the city’s best offerings. Make your Samos experience cost-effective and relaxing—secure your stay now!

  Call (855) 234-2997 to book with an agent.
  4.4 miles from Samos, MO 63834

Starting at

$60.99

per night

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Quality Inn Charleston Sikeston

102 Drake St Charleston, MO

Guests bound for Samos will find inviting comfort at Quality Inn Charleston Sikeston, with secure rooms starting at $67.99, providing a warm and welcoming space ideal for rest. Enjoy the extra comfort of Quality Inn's upgraded bedding options, including pillow-top mattresses and luxury linens.

From Quality Inn Charleston Sikeston, a brief drive delivers guests to downtown Samos, where the city’s most popular destinations await exploration. Make the most of your time in Samos with a hotel that enhances your stay—lock in today!

  Call (855) 234-7135 to book with an agent.
  4.9 miles from Samos, MO 63834

Starting at

$67.99

per night

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Quality Inn Cairo I-57

13201 Kessler Road Cairo, IL

For an affordable and welcoming stay near Samos, Quality Inn Cairo I-57 offers budget-friendly rooms with rates from $80.99, creating a clean and comfortable atmosphere. Experience the local area with Quality Inn's guided tours, offering guests insights into the history and attractions of the destination.

A peaceful retreat awaits at Quality Inn Cairo I-57, where calm surroundings make for a restful stay and downtown Samos remains close by. Stay smart and relaxed in Samos with value-driven amenities—book your room now!

  Call (855) 236-8982 to book with an agent.
  12.7 miles from Samos, MO 63834

Starting at

$80.99

per night

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Days Inn&Suites by Wyndham Sikeston

220 South Interstate Dr Sikeston, MO

With rates beginning at $73.99, Days Inn&Suites by Wyndham Sikeston offers budget-conscious comfort for travelers to Samos, creating a inviting and inviting space perfect for relaxation. Discover our blend of convenience and value, with amenities and services designed to make your stay stress-free.

At Days Inn&Suites by Wyndham Sikeston, guests can relax in quiet surroundings while keeping downtown Samos within easy reach for city exploration. Stay smart and enjoy Samos with a practical, comfortable hotel—book today!

  Call (855) 236-8982 to book with an agent.
  14.1 miles from Samos, MO 63834

Starting at

$73.99

per night

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Country Yard Inn&Suite

110 South Interstate Drive Sikeston, MO

For a restful stay near Samos, Country Yard Inn&Suite offers harmonious accommodations with rooms starting at $54.99, creating a clean, welcoming environment ideal for relaxation. Find a cozy and economical stay in rooms that provide essential amenities and a welcoming atmosphere.

Rest in the serene environment of Country Yard Inn&Suite, with downtown Samos nearby for a blend of quiet and city excitement. Experience Samos with comfort and budget-savvy rates—lock in your stay today!

  Call (855) 234-7135 to book with an agent.
  14.1 miles from Samos, MO 63834

Starting at

$54.99

per night

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Best Western Plus Sikeston

120 South Interstate Drive Sikeston, MO

For an affordable and comfortable stay, Best Western Plus Sikeston offers inviting rooms with rates starting at $89.99, creating a clean, welcoming environment for guests. Appreciate the modern art and décor throughout Best Western Plus hotels, which enhance the aesthetic and atmosphere of each property.

Escape the hustle of downtown Samos at Best Western Plus Sikeston, where peaceful surroundings create a restful stay. Make every day in Samos a pleasure with a hotel that goes above and beyond—secure now!

  Call (855) 235-0725 to book with an agent.
  14.2 miles from Samos, MO 63834

Starting at

$89.99

per night

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Travel Inn & Suites Sikeston / Miner (i-55 Exit 67)

100 Matthews Lane Sikeston, MO

Guests visiting Samos will appreciate the inviting comfort at Travel Inn & Suites Sikeston / Miner (i-55 Exit 67), with budget-friendly rooms starting at $65.99, creating a clean, welcoming space. Relax in rooms that provide the necessities for a comfortable stay, focusing on cleanliness, comfort, and practical amenities.

For those looking to unwind, Travel Inn & Suites Sikeston / Miner (i-55 Exit 67) provides a restful retreat while keeping downtown Samos close enough for exploration. Treat yourself to a memorable Samos trip with well-equipped, cost-friendly accommodations—reserve today!

  Call (855) 234-5074 to book with an agent.
  14.4 miles from Samos, MO 63834

Starting at

$65.99

per night

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Comfort Inn & Suites Sikeston I-55

109 Matthews Ln Sikeston, MO

At Comfort Inn & Suites Sikeston I-55, guests bound for Samos can unwind in cushy accommodations with rooms starting at $106.99, creating a warm, welcoming atmosphere. Navigate your trip with ease, thanks to Comfort Inn's central locations and accessibility to public transportation.

Situated away from the city’s noise, Comfort Inn & Suites Sikeston I-55 offers calm and comfort, while downtown Samos remains a simple drive away. Make your Samos visit memorable and stress-free with inviting amenities—lock in today!

  Call (855) 235-6136 to book with an agent.
  14.4 miles from Samos, MO 63834

Starting at

$106.99

per night

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Super 8 by Wyndham Sikeston / Miner Area

2609 East Malone Ave Sikeston, MO

At Super 8 by Wyndham Sikeston / Miner Area, guests visiting Samos will find inviting rooms starting at $69.99, providing a welcoming, affordable environment ideal for relaxation and comfort. Snack anytime with the convenience of Super 8’s vending options, available 24/7 to satisfy those late-night or between-meals hungers.

Unwind in the serene environment of Super 8 by Wyndham Sikeston / Miner Area, knowing that downtown Samos remains close by for easy access to city adventures. Choose value-driven comfort for your Samos travels and enjoy more—lock in now!

  Call (855) 239-5277 to book with an agent.
  14.6 miles from Samos, MO 63834

Starting at

$69.99

per night

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Hampton Inn Sikeston

1240 Commerce Drive Sikeston, MO

With rates from $126.99, Hampton Inn Sikeston provides reassuring comfort for guests traveling to Samos, creating a warm and welcoming environment ideal for rest. Experience the fresh design of Hampton’s renovated properties, where modern aesthetics meet the comfort and quality the brand is known for.

Travelers seeking relaxation will appreciate Hampton Inn Sikeston, offering a quiet escape with downtown Samos still accessible for sightseeing. Choose accommodations in Samos that offer a great blend of value and comfort—book now!

  Call (855) 235-6136 to book with an agent.
  16.8 miles from Samos, MO 63834

Starting at

$126.99

per night

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Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel

115 Hospitality Dr Sikeston, MO

For an inviting and budget-conscious stay near Samos, Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel offers relaxed rooms with rates beginning at $144.00, creating a welcoming atmosphere for rest. Enjoy the privacy of separate sleeping and living areas in the suites at Holiday Inn Express, ideal for business and leisure travelers.

Rest easy at Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel, where peaceful surroundings create a restful stay and downtown Samos is still nearby. Stay in style and save while visiting Samos with accommodations that meet your needs—secure now!

  Call (855) 236-8982 to book with an agent.
  16.8 miles from Samos, MO 63834

Starting at

$144.00

per night

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La Center Motel

474 West Kentucky Dr La Center, KY

With budget-friendly rooms starting at $65.99, La Center Motel is a convenient option for travelers to Samos, creating a homely and inviting space perfect for rest. Experience a stay that focuses on the essentials, providing comfort and value in rooms that cater to budget-savvy travelers.

Discover the convenience of La Center Motel, a peaceful location with Samos's attractions accessible whenever you're ready to explore. Plan your Samos trip with ease and savings in mind—reserve your hotel room now!

  Call (855) 236-8982 to book with an agent.
  21.6 miles from Samos, MO 63834

Starting at

$65.99

per night

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Regency Inn

128 CHEEKWOOD LN Ullin, IL

Guests visiting Samos will find Regency Inn a practical option, with rates starting at $94.99, creating a clean and inviting environment perfect for relaxation. Experience the basics in rooms that provide dependable amenities, ensuring a pleasant stay at a budget-friendly price.

Find your ideal getaway at Regency Inn, where calm surroundings and the convenience of Samos come together seamlessly. Stay affordably and enjoy Samos with added value and ease—reserve now!

  Call (855) 233-0132 to book with an agent.
  28.5 miles from Samos, MO 63834

Starting at

$94.99

per night

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Travel Inn

301 Route Ad Marston, MO

With rates beginning at $60.96, Travel Inn is a smart choice for travelers to Samos, creating a intimate-feeling space perfect for rest and relaxation. Stay in a setting that offers increased comfort and amenities, providing a superior experience without the premium price.

Enjoy a quiet escape at Travel Inn, where guests can recharge and still visit Samos's bustling streets whenever they choose. Take advantage of inviting accommodations perfect for your Samos visit—reserve now!

  Call (855) 236-8982 to book with an agent.
  30.4 miles from Samos, MO 63834

Starting at

$60.96

per night

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Holiday Inn Express & Suites Union City an IHG Hotel

810 BREAM BOULEVARD Union City, TN

Guests bound for Samos will find inviting comfort at Holiday Inn Express & Suites Union City an IHG Hotel, with inviting rooms starting at $139.00, creating a warm and welcoming space perfect for relaxation. Stay connected with free high-speed Wi-Fi at Holiday Inn Express, making it easy to work or keep in touch while on the go.

Escape the everyday rush at Holiday Inn Express & Suites Union City an IHG Hotel, a restful getaway where Samos's attractions are always within easy reach. Discover the best value for your Samos stay with a hotel that won’t disappoint—reserve now!

  Call (855) 234-7135 to book with an agent.
  31.6 miles from Samos, MO 63834

Starting at

$139.00

per night

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Sleep Inn

1111 BLue Heron Lane Union City, TN

Guests visiting Samos will find inviting accommodations at Sleep Inn, with rooms beginning at $98.99, creating a clean, inviting environment perfect for rest. Discover Sleep Inn's value-driven amenities, including complimentary breakfast and Wi-Fi, adding to your overall stay experience.

Take a break from the busy city life at Sleep Inn, a quiet escape that's still connected to the heart of Samos. Discover a Samos stay that makes every moment worthwhile with practical, cost-saving lodging—lock in today!

  Call (855) 234-7135 to book with an agent.
  31.9 miles from Samos, MO 63834

Starting at

$98.99

per night

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MainStay Suites

1111 Blue Heron Lane Building B Union City, TN

At MainStay Suites, guests bound for Samos can enjoy tranquil accommodations with rates starting at $106.99, creating a clean, inviting space perfect for relaxation. Stay comfortable with MainStay Suites’ adjustable bed options, ensuring a good night’s sleep tailored to your preferences.

Enjoy a relaxing stay at MainStay Suites, where a quiet environment allows you to unwind with the option to visit Samos at your leisure. Get ready for a comfortable Samos adventure with cost-effective, inviting accommodations—lock in now!

  Call (855) 235-6136 to book with an agent.
  33.0 miles from Samos, MO 63834

Starting at

$106.99

per night

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Courtyard by Marriott Cape Girardeau Downtown

400 Broadway St. Cape Girardeau, MO

Courtyard by Marriott Cape Girardeau Downtown offers a relaxing stay for travelers to Samos, with pleasant accommodations providing comfort, with nightly rates beginning at an affordable $149.99. Indulge in Courtyard's thoughtful amenities, from in-room mini-fridges to 24-hour marketplaces for snacks and essentials.

Stay at Courtyard by Marriott Cape Girardeau Downtown to experience a quiet atmosphere, where restful nights are balanced by the option to explore Samos. Enjoy your Samos adventure with accommodations that make every detail count—reserve now!

  Call (855) 234-7135 to book with an agent.
  33.2 miles from Samos, MO 63834

Starting at

$149.99

per night

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Hospitality House Union City US 51

1221 West Reelfoot Ave Union City, TN

Guests traveling to Samos will find inviting accommodations at Hospitality House Union City US 51, with rooms starting at $65.99, creating a clean and welcoming environment ideal for relaxation. Stay in rooms that enhance your travel experience with additional amenities, ensuring a comfortable and budget-friendly stay.

Unwind at Hospitality House Union City US 51, where a calm atmosphere makes it easy to enjoy Samos whenever you wish. Find the perfect Samos escape with accommodations that don’t break the bank—lock in today!

  Call (855) 234-5074 to book with an agent.
  33.2 miles from Samos, MO 63834

Starting at

$65.99

per night

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Candlewood Suites Cape Girardeau an IHG Hotel

485 South Mount Auburn Rd Cape Girardeau, MO

For a serene and inviting stay, Candlewood Suites Cape Girardeau an IHG Hotel offers budget-friendly accommodations with rates from $117.00, creating a warm and comfortable environment. Candlewood Suites is more than just a place to stay; it's a lifestyle choice for comfortable and efficient extended living.

Relax at Candlewood Suites Cape Girardeau an IHG Hotel, where restful nights are paired with quick access to Samos for adventure during the day. Take your Samos trip to the next level with well-thought-out, budget-friendly lodging—lock in today!

  Call (855) 234-5074 to book with an agent.
  33.3 miles from Samos, MO 63834

Starting at

$117.00

per night

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Fairfield Inn & Suites by Marriott Cape Girardeau

433 CAPE WEST CROSSINGS Cape Girardeau, MO

For those bound for Samos, Fairfield Inn & Suites by Marriott Cape Girardeau offers tucked away comfort with rooms starting at $144.99, creating a clean, comfortable space perfect for unwinding. Appreciate the convenience of Fairfield's express check-in service for elite members, offering an expedited start to your stay.

Enjoy a tranquil stay at Fairfield Inn & Suites by Marriott Cape Girardeau, and venture into Samos whenever you're ready for more excitement. Make Samos travel a breeze with a hotel that blends comfort and savings—secure now!

  Call (855) 236-8982 to book with an agent.
  33.4 miles from Samos, MO 63834

Starting at

$144.99

per night

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The Riverview

777 Main St Cape Girardeau, MO

A warm stay awaits at The Riverview as you visit Samos, where inviting rooms provide relaxation and comfort, with rates beginning at $137.99. Find a blend of luxury and functionality in rooms that offer a superior level of amenities and sophisticated design.

For a tranquil experience, The Riverview offers spacious accommodations with Samos only a short journey away. Take in the elegance of Samos with a hotel that sets the standard for sophistication—secure now!

  Call (855) 235-0725 to book with an agent.
  33.5 miles from Samos, MO 63834

Starting at

$137.99

per night

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Country Hearth Inn & Suites Union City

2009 West Reelfoot Avenue Union City, TN

With affordable rooms beginning at $62.99, Country Hearth Inn & Suites Union City is a practical choice for guests visiting Samos, creating a clean and inviting space ideal for rest. Experience practical accommodations, where rooms are designed with the essentials for a comfortable and convenient stay.

Stay at Country Hearth Inn & Suites Union City to enjoy both peace and convenience, with quiet rooms just a short drive from Samos's lively attractions. Experience Samos with peace of mind, knowing your hotel offers great savings—book now!

  Call (855) 234-7135 to book with an agent.
  33.5 miles from Samos, MO 63834

Starting at

$62.99

per night

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