The best deals on hotels when visiting Edisto in South Carolina.

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Top 24 Hotels In Edisto, South Carolina 29115

Orangeburg Inn & Suites

1415 John C Calhoun Dr Orangeburg, SC

Guests headed to Edisto will enjoy the delightful accommodations at Orangeburg Inn & Suites, where rooms start at $60.99, creating a warm, welcoming environment perfect for rest. Enjoy practical comfort in rooms that offer essential amenities, making your stay both convenient and affordable.

At Orangeburg Inn & Suites, guests are never far from downtown Edisto, where a short drive brings them to the city’s most iconic destinations for exploration. Plan your Edisto visit wisely with budget-friendly, inviting accommodations—book now!

  Call (855) 236-8982 to book with an agent.
  1.9 miles from Edisto, SC 29115

Starting at

$60.99

per night

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Baymont by Wyndham Orangeburg North

3583 Saint Matthews Rd Orangeburg, SC

For those headed to Edisto, Baymont by Wyndham Orangeburg North offers budget-friendly comfort with rooms starting at $80.99, creating a clean, welcoming environment perfect for unwinding. Relax in Baymont by Wyndham’s indoor or outdoor pools, perfect for a refreshing swim or a leisurely day in the sun.

With a quick drive into downtown Edisto, guests at Baymont by Wyndham Orangeburg North can enjoy the best of both worlds: city exploration and a relaxing retreat. Make your Edisto journey relaxing and budget-smart with well-appointed lodging—secure today!

  Call (855) 235-6136 to book with an agent.
  6.6 miles from Edisto, SC 29115

Starting at

$80.99

per night

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Super 8 by Wyndham Orangeburg

3608 Saint Matthews Rd Orangeburg, SC

For a restful stay near Edisto, Super 8 by Wyndham Orangeburg offers affordable comfort with rooms beginning at $71.99, creating a clean, welcoming environment ideal for relaxation. Enjoy a peaceful night's sleep in Super 8's well-appointed rooms, designed for maximum comfort and relaxation.

With Edisto a drive away, guests at Super 8 by Wyndham Orangeburg can enjoy the peace and quiet of being slightly removed from the center while still having easy access to the city. Plan your Edisto trip with comfort and affordability in mind—secure your room today!

  Call (855) 233-7850 to book with an agent.
  6.7 miles from Edisto, SC 29115

Starting at

$71.99

per night

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Travelodge by Wyndham Orangeburg

3620 Saint Matthews Rd Orangeburg, SC

For a warm-hearted and budget-friendly stay, Travelodge by Wyndham Orangeburg offers affordable rooms with rates starting at $72.99, creating a welcoming environment ideal for guests visiting Edisto. Savor a moment of relaxation with Travelodge's in-room amenities, including coffee makers for a fresh morning start.

With downtown Edisto still accessible by car, guests at Travelodge by Wyndham Orangeburg can enjoy the city’s offerings while retreating to a more peaceful setting afterward. Enjoy added comfort and savings while exploring Edisto—lock in your stay now!

  Call (855) 234-7135 to book with an agent.
  6.7 miles from Edisto, SC 29115

Starting at

$72.99

per night

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Quality Inn & Suites

3671 Saint Matthews Rd Orangeburg, SC

Guests traveling to Edisto will find inviting accommodations at Quality Inn & Suites, where cozy-like rooms start at $104.99, creating a warm and welcoming space. Appreciate Quality Inn's commitment to accessibility, offering rooms and facilities designed for guests with disabilities.

From Quality Inn & Suites, a short drive delivers guests into downtown Edisto, where they can explore the city’s top spots before retreating to a serene stay. Make your Edisto adventure simple and enjoyable with inviting hotel options—lock in now!

  Call (855) 233-0132 to book with an agent.
  6.7 miles from Edisto, SC 29115

Starting at

$104.99

per night

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Hampton Inn & Suites Orangeburg

749 Citadel Road Orangeburg, SC

Guests traveling to Edisto will find mellifluous accommodations at Hampton Inn & Suites Orangeburg, with rooms starting at $158.99, creating a warm and welcoming atmosphere. Experience a personalized welcome with unique amenities in select Hampton rooms, including local snacks and drinks to greet you upon arrival.

From Hampton Inn & Suites Orangeburg, a convenient drive takes guests to downtown Edisto, where they can explore the city’s highlights before returning to a more peaceful retreat. Make the most of your Edisto travels with practical, inviting hotel options—lock in now!

  Call (855) 235-6136 to book with an agent.
  6.7 miles from Edisto, SC 29115

Starting at

$158.99

per night

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Comfort Inn & Suites

746 Citadel Rd Orangeburg, SC

At Comfort Inn & Suites, travelers visiting Edisto can enjoy mellifluous accommodations with rooms from $137.99, creating a warm, inviting space perfect for relaxation. Experience the blend of comfort and value at Comfort Inn by Choice Hotels, a trusted choice for travelers seeking affordable accommodations.

Guests staying at Comfort Inn & Suites will appreciate the quiet atmosphere, while downtown Edisto remains accessible by car for easy city exploration. Enjoy an exceptional Edisto stay with added perks at a budget-friendly price—reserve today!

  Call (855) 234-2997 to book with an agent.
  6.8 miles from Edisto, SC 29115

Starting at

$137.99

per night

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Fairfield Inn by Marriott Orangeburg

663 Citadel Road Orangeburg, SC

At Fairfield Inn by Marriott Orangeburg, guests bound for Edisto can unwind in plush accommodations with rooms starting at $164.99, creating a warm, welcoming atmosphere. Take a refreshing break in Fairfield’s tea lounges, offering a selection of herbal and traditional teas throughout the day.

The calm atmosphere at Fairfield Inn by Marriott Orangeburg makes for a restful stay, with downtown Edisto just a drive away for easy access to the city’s highlights. Step into Edisto with confidence, knowing your hotel delivers more for less—reserve now!

  Call (855) 234-7135 to book with an agent.
  6.8 miles from Edisto, SC 29115

Starting at

$164.99

per night

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Days Inn by Wyndham Orangeburg

3691 Saint Matthews Rd Orangeburg, SC

For a gentle stay near Edisto, Days Inn by Wyndham Orangeburg offers inviting accommodations with rooms starting at $69.99, creating a welcoming space perfect for relaxation. Experience the convenience and affordability of Days Inn, making it an ideal choice for budget-conscious travelers.

Guests at Days Inn by Wyndham Orangeburg will appreciate the calm atmosphere of the hotel, with downtown Edisto still accessible by car for a day of city exploration. Plan your Edisto getaway with a welcoming, budget-friendly hotel—book today!

  Call (855) 235-0725 to book with an agent.
  6.8 miles from Edisto, SC 29115

Starting at

$69.99

per night

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Tru by Hilton Orangeburg

739 Citadel Road Orangeburg, SC

At Tru by Hilton Orangeburg, travelers visiting Edisto can unwind in comforting comfort with rooms beginning at $154.99, creating a warm and welcoming environment. Stay refreshed with the ice machines conveniently located on each floor at Tru by Hilton, perfect for cooling down your beverages.

With downtown Edisto still within easy reach, guests at Tru by Hilton Orangeburg can balance city adventures with the peaceful surroundings of the hotel. Plan your Edisto adventure with extra comfort at a price you’ll love—book today!

  Call (855) 235-6136 to book with an agent.
  6.8 miles from Edisto, SC 29115

Starting at

$154.99

per night

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Sleep Inn Orangeburg

3689 Saint Matthews Rd Orangeburg, SC

With budget-friendly rooms from $124.99, Sleep Inn Orangeburg provides hospitable accommodations for travelers bound for Edisto, creating a warm, welcoming space. Unwind in Sleep Inn’s spacious accommodations, where thoughtful design maximizes both comfort and functionality for guests.

Guests staying at Sleep Inn Orangeburg will appreciate the quiet surroundings, with downtown Edisto still accessible for a day of sightseeing and adventure. Choose a Edisto hotel that keeps you comfortable and your budget intact—reserve now!

  Call (855) 239-5277 to book with an agent.
  6.9 miles from Edisto, SC 29115

Starting at

$124.99

per night

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Holiday Inn Express & Suites Orangeburg

118 Sleep Inn Road Orangeburg, SC

For an inviting and budget-conscious stay near Edisto, Holiday Inn Express & Suites Orangeburg offers easygoing rooms with rates beginning at $141.99, creating a welcoming atmosphere for rest. Relax in the contemporary comfort of Holiday Inn Express's lobby areas, featuring sleek furnishings and inviting spaces for guests to gather.

With Edisto just a drive away, guests at Holiday Inn Express & Suites Orangeburg can experience the city’s highlights while staying in a more peaceful, relaxed environment. Discover a welcoming, cost-effective hotel perfect for your Edisto getaway—secure today!

  Call (855) 234-5074 to book with an agent.
  6.9 miles from Edisto, SC 29115

Starting at

$141.99

per night

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SpringHill Suites by Marriott Orangeburg

675 Citadel Rd Orangeburg, SC

With rooms beginning at $149.99, SpringHill Suites by Marriott Orangeburg provides affordable comfort for travelers to Edisto, creating a warm and welcoming space perfect for relaxation. SpringHill Suites accommodates a variety of travelers, from solo adventurers to families and business professionals.

At SpringHill Suites by Marriott Orangeburg, visitors can unwind in the peaceful surroundings of the hotel, while downtown Edisto remains within easy reach for exploration. Choose a hotel that makes your Edisto trip both practical and enjoyable—secure your stay today!

  Call (855) 239-4019 to book with an agent.
  7.0 miles from Edisto, SC 29115

Starting at

$149.99

per night

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Days Inn by Wyndham Orangeburg South

3402 Five Chop Rd Orangeburg, SC

Guests bound for Edisto can relax at Days Inn by Wyndham Orangeburg South, where budget-friendly rooms start at $74.99, creating a warm and comfortable space ideal for unwinding. Explore vibrant neighborhoods with convenient access to dining and shopping, thanks to our strategically located properties.

From Days Inn by Wyndham Orangeburg South, a scenic drive takes guests into downtown Edisto, offering a balance of relaxation and easy access to the city's top spots. Book an inviting hotel that won’t break the bank for your Edisto visit—secure today!

  Call (855) 235-0725 to book with an agent.
  10.2 miles from Edisto, SC 29115

Starting at

$74.99

per night

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Peach Tree Inn

111 Conners Dr St. George, SC

At Peach Tree Inn, travelers to Edisto will find gentle rooms with rates starting at $60.99, creating a clean, welcoming space perfect for a relaxing stay. Stay in rooms that elevate your travel experience with extra comforts and a welcoming atmosphere at an affordable price.

Discover the ideal balance of serenity and access at Peach Tree Inn, positioned just a drive away from the action in Edisto. Relax and explore Edisto with ease, thanks to a hotel that prioritizes your comfort—secure now!

  Call (855) 239-5277 to book with an agent.
  23.9 miles from Edisto, SC 29115

Starting at

$60.99

per night

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Comfort Inn & Suites Santee

221 Britain St Santee, SC

With rates beginning at $108.99, Comfort Inn & Suites Santee provides budget-friendly comfort for guests bound for Edisto, creating a charming and inviting environment. Stay informed with Comfort Inn's local event and activity recommendations, helping you make the most of your visit.

Find your peaceful escape at Comfort Inn & Suites Santee, offering quiet surroundings and easy access to the lively offerings of Edisto. Choose a hotel that adds value to your Edisto journey—lock in your room now!

  Call (855) 234-7135 to book with an agent.
  24.4 miles from Edisto, SC 29115

Starting at

$108.99

per night

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Holiday Inn Santee an IHG Hotel

139 Bradford Blvd Santee, SC

Holiday Inn Santee an IHG Hotel provides a friendly retreat for travelers to Edisto, where quality accommodations offer warmth and relaxation, with nightly rates starting at $134.00. Explore your surroundings with Holiday Inn’s bike rental service, a fun and green way to discover local sights.

Found just outside of Edisto, Holiday Inn Santee an IHG Hotel provides the ideal base for exploring the area and returning to peaceful lodgings. Uncover Edisto lodging that turns your trip into an unforgettable experience—secure now!

  Call (855) 234-5074 to book with an agent.
  24.5 miles from Edisto, SC 29115

Starting at

$134.00

per night

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Baymont by Wyndham Santee

249 Britain Street Santee, SC

For budget-savvy travelers, Baymont by Wyndham Santee offers safe comfort with rates beginning at $77.99, creating a warm and inviting atmosphere perfect for relaxation. Benefit from Baymont by Wyndham’s 24-hour reception, where friendly staff are available to help with any request, any time.

Enjoy a relaxing stay at Baymont by Wyndham Santee, where a quiet environment allows you to unwind with the option to visit Edisto at your leisure. Choose a Edisto hotel that turns your trip into a seamless, budget-friendly experience—reserve now!

  Call (855) 233-0132 to book with an agent.
  24.5 miles from Edisto, SC 29115

Starting at

$77.99

per night

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Quality Inn & Suites

8929 Old Number Six Highway Santee, SC

At Quality Inn & Suites, travelers visiting Edisto can enjoy inviting comfort with rooms beginning at $66.99, creating a clean and welcoming environment for relaxation. Relax with Quality Inn's thoughtful in-room amenities, including microwaves, refrigerators, and coffee makers in select rooms.

Relax at Quality Inn & Suites, where a calm environment contrasts with the exciting attractions of Edisto just a short drive away. Experience Edisto in style and on budget with accommodations tailored for you—lock in today!

  Call (855) 236-8982 to book with an agent.
  24.5 miles from Edisto, SC 29115

Starting at

$66.99

per night

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Tru by Hilton Santee

263 Britain St. & 273 Britain St. Santee, SC

At Tru by Hilton Santee, travelers bound for Edisto will find budget-friendly comfort with rooms starting at $118.99, creating a warm-hearted, inviting environment for unwinding. Relax with the pet-friendly policies at Tru by Hilton, welcoming your furry companions for a small additional fee.

At Tru by Hilton Santee, guests can experience the balance of a quiet stay with the convenience of being close to Edisto's attractions. Make every moment in Edisto count with a hotel that offers more for less—reserve your room now!

  Call (855) 234-5074 to book with an agent.
  24.5 miles from Edisto, SC 29115

Starting at

$118.99

per night

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Red Roof Inn Santee

9091 Old Highway 6 Santee, SC

With rates beginning at $68.99, Red Roof Inn Santee is an ideal option for travelers visiting Edisto, offering restorative rooms that provide a welcoming, comfortable experience. Feel welcomed by Red Roof Inn’s pet-friendly accommodations, where your pets can stay by your side throughout your visit.

Discover a quiet escape at Red Roof Inn Santee, where the bustle of Edisto is close enough to explore at your leisure. Enjoy a stress-free Edisto trip with cozy, budget-wise lodging—reserve today!

  Call (855) 233-0132 to book with an agent.
  24.5 miles from Edisto, SC 29115

Starting at

$68.99

per night

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Best Western Plus Santee Inn

I 95 Exit 98 Santee, SC

For an affordable and comfortable stay near Edisto, Best Western Plus Santee Inn offers hospitable accommodations with rooms beginning at $105.99, creating a welcoming environment. Relax in the dedicated meditation and quiet rooms available at Best Western Plus, offering a space for reflection and relaxation.

Take a break from the city noise at Best Western Plus Santee Inn, offering restful accommodations and quick access to Edisto's best spots. Take advantage of a Edisto hotel that combines quality with cost-effective rates—secure now!

  Call (855) 235-6136 to book with an agent.
  24.9 miles from Edisto, SC 29115

Starting at

$105.99

per night

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Hampton Inn Santee I-95

9060 Old Number Six Hwy Santee, SC

For a restful stay, Hampton Inn Santee I-95 offers appealing accommodations with rates from $137.99, creating a welcoming space ideal for travelers visiting Edisto. Stay productive with Hampton's convenient business centers, equipped with computers, printers, and everything you need to stay on task.

Enjoy a quiet stay at Hampton Inn Santee I-95, with spacious accommodations that offer both comfort and proximity to Edisto. Embrace the best of Edisto with a welcoming, cost-effective hotel—book your stay today!

  Call (855) 239-4019 to book with an agent.
  24.9 miles from Edisto, SC 29115

Starting at

$137.99

per night

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Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy Santee, SC

At Fairfield Inn & Suites by Marriott Santee, guests bound for Edisto can unwind in restful comfort with rooms starting at $149.99, creating a clean, inviting space ideal for relaxation. Stay connected with Fairfield's complimentary Wi-Fi, ensuring you can work or browse with ease from anywhere in the hotel.

Discover a peaceful retreat at Fairfield Inn & Suites by Marriott Santee, where quiet lodgings are paired with easy access to Edisto's best attractions. Discover how great your Edisto stay can be with thoughtful, cost-effective amenities—secure now!

  Call (855) 239-4019 to book with an agent.
  24.9 miles from Edisto, SC 29115

Starting at

$149.99

per night

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