The best deals on hotels when visiting Lewis Crossroads in South Carolina.

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Top 24 Hotels In Lewis Crossroads, South Carolina 29550

The Landmark Inn

1301 South 4th Street Hartsville, SC

Guests traveling to Lewis Crossroads will appreciate the inviting comfort at The Landmark Inn, where budget-friendly rooms start at $85.00, creating a warm, welcoming environment. Stay in accommodations that deliver extra comfort and amenities, ensuring a satisfying and budget-friendly experience.

From The Landmark Inn, a simple drive delivers guests to downtown Lewis Crossroads, where they can enjoy the city’s top attractions before returning to tranquility. Relax and explore Lewis Crossroads knowing your accommodations provide excellent value—book today!

  Call (855) 233-0132 to book with an agent.
  5.4 miles from Lewis Crossroads, SC 29550

Starting at

$85.00

per night

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Raceway Inn

705 Washington St Darlington, SC

For a comfortable and inviting stay, Raceway Inn offers budget-friendly rooms with rates from $60.99, creating a inviting environment ideal for travelers bound for Lewis Crossroads. Find comfort in rooms that cater to budget-conscious travelers, offering essential amenities and a clean, safe environment.

At Raceway Inn, guests can enjoy the comfort of a quieter environment, while downtown Lewis Crossroads remains within reach for all their city adventures. Settle in and enjoy your Lewis Crossroads stay with amenities that make all the difference—reserve now!

  Call (855) 233-0132 to book with an agent.
  5.8 miles from Lewis Crossroads, SC 29550

Starting at

$60.99

per night

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Hampton Inn & Suites Hartsville

203 East Carolina Ave. Hartsville, SC

For a comfortable and budget-friendly stay, Hampton Inn & Suites Hartsville offers inviting rooms with rates beginning at $170.99, creating a intimate environment near Lewis Crossroads. Opt for enhanced comfort with upgraded bedding options available in select Hampton rooms, featuring premium linens for a luxurious sleep.

At Hampton Inn & Suites Hartsville, guests can unwind in a calm setting, while downtown Lewis Crossroads remains easily accessible for a day of sightseeing and adventure. Uncover the charm of Lewis Crossroads with a hotel that offers top-notch comfort for less—book today!

  Call (855) 233-7850 to book with an agent.
  6.6 miles from Lewis Crossroads, SC 29550

Starting at

$170.99

per night

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Fairfield Inn by Marriott Hartsville

200 South 4th St Hartsville, SC

At Fairfield Inn by Marriott Hartsville, travelers to Lewis Crossroads will find affordable comfort with rooms beginning at $169.99, creating a clean and welcoming environment for unwinding. Discover the friendly atmosphere of Fairfield's community dining events, where guests can enjoy themed dinners and local cuisine.

At Fairfield Inn by Marriott Hartsville, visitors can enjoy the calm atmosphere of the hotel, while downtown Lewis Crossroads remains easily accessible for a day of adventure. Choose a hotel in Lewis Crossroads that gives you more for your money—reserve your stay now!

  Call (855) 234-5074 to book with an agent.
  6.7 miles from Lewis Crossroads, SC 29550

Starting at

$169.99

per night

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Tru by Hilton Florence I-95

2140 West Lucas Street Florence, SC

With rates beginning at $138.99, Tru by Hilton Florence I-95 is a practical choice for guests visiting Lewis Crossroads, providing a enveloping and inviting space ideal for relaxation. Appreciate the vibrant and modern artwork throughout Tru by Hilton, reflecting the brand’s commitment to contemporary style and creativity.

For a peaceful experience, Tru by Hilton Florence I-95 offers a quiet retreat, while downtown Lewis Crossroads remains easily accessible by car. Make Lewis Crossroads travel feel effortless with a cost-effective, welcoming hotel—book now!

  Call (855) 239-5277 to book with an agent.
  11.3 miles from Lewis Crossroads, SC 29550

Starting at

$138.99

per night

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Microtel Inn & Suites by Wyndham Florence

1912 Enterprise Dr Florence, SC

For travelers visiting Lewis Crossroads, Microtel Inn & Suites by Wyndham Florence offers inviting accommodations with rooms starting at $77.99, creating a calm, welcoming space perfect for relaxation. Appreciate the streamlined design and functionality of Microtel's guest rooms, optimized for your comfort and convenience.

From Microtel Inn & Suites by Wyndham Florence, a scenic drive takes guests into downtown Lewis Crossroads, where they can explore the city's highlights before returning to the tranquility of the hotel. Plan your Lewis Crossroads getaway with a hotel that offers great value—lock in now!

  Call (855) 235-6136 to book with an agent.
  11.3 miles from Lewis Crossroads, SC 29550

Starting at

$77.99

per night

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Sleep Inn Florence North

1833 Florence Park Dr Florence, SC

Guests visiting Lewis Crossroads will appreciate the inviting comfort at Sleep Inn Florence North, where intimate rooms begin at $73.99, creating a warm, welcoming atmosphere. Appreciate the stylish and spacious bathrooms at Sleep Inn, equipped with modern fixtures and bright lighting to start your day right.

For a restful getaway, Sleep Inn Florence North offers calm surroundings, while downtown Lewis Crossroads remains accessible for a day of sightseeing. Treat yourself to an affordable, inviting hotel experience in Lewis Crossroads—book today!

  Call (855) 235-6136 to book with an agent.
  11.4 miles from Lewis Crossroads, SC 29550

Starting at

$73.99

per night

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Days Inn by Wyndham Florence / I-95 North

2111 West Lucas St. / I 95 Florence, SC

At Days Inn by Wyndham Florence / I-95 North, guests traveling to Lewis Crossroads can unwind in budget-conscious accommodations with rooms beginning at $68.99, creating a warm and inviting space. Enjoy essential in-room amenities such as coffee makers and cozy bedding, designed to make your stay as homely as possible.

The serene setting at Days Inn by Wyndham Florence / I-95 North makes for a peaceful stay, with downtown Lewis Crossroads still close enough for guests to explore the city. Enjoy more of Lewis Crossroads with budget-friendly, inviting accommodations—book now!

  Call (855) 236-8982 to book with an agent.
  11.4 miles from Lewis Crossroads, SC 29550

Starting at

$68.99

per night

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Comfort Suites Florence I-95

2120 West Lucas Street Florence, SC

Guests visiting Lewis Crossroads can enjoy inviting accommodations at Comfort Suites Florence I-95, where budget-friendly rooms start at $141.99, creating a welcoming space. Plan your city tour with help from Comfort Suites' on-site tour desk, offering tickets and information about local attractions.

Escape the hustle of downtown Lewis Crossroads and unwind at Comfort Suites Florence I-95, where the city remains within easy reach for a day of adventure. Discover how great your Lewis Crossroads stay can be with thoughtful, cost-effective amenities—secure now!

  Call (855) 236-8982 to book with an agent.
  11.4 miles from Lewis Crossroads, SC 29550

Starting at

$141.99

per night

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Hampton Inn & Suites Florence North I-95

1735 Stokes Road Florence, SC

For an affordable stay near Lewis Crossroads, Hampton Inn & Suites Florence North I-95 offers inviting rooms with rates starting at $134.99, creating a clean, comfortable atmosphere perfect for relaxation. Savor the quality of Hampton’s premium coffee selection, featuring top-tier brands and specialty blends to kickstart your morning.

Rest in the serene surroundings of Hampton Inn & Suites Florence North I-95, knowing that downtown Lewis Crossroads is still within reach for easy city access. Find the comfort you need at a price you’ll love during your Lewis Crossroads adventure—secure now!

  Call (855) 233-0132 to book with an agent.
  11.5 miles from Lewis Crossroads, SC 29550

Starting at

$134.99

per night

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La Quinta Inn & Suites by Wyndham Florence

2123 West Lucas St Florence, SC

Guests headed to Lewis Crossroads can unwind in affordable comfort at La Quinta Inn & Suites by Wyndham Florence, where restorative rooms start at $118.99, creating a clean, welcoming atmosphere. Discover local attractions with ease, thanks to La Quinta's knowledgeable staff ready to provide recommendations and directions.

For a serene stay, La Quinta Inn & Suites by Wyndham Florence offers quiet surroundings, while downtown Lewis Crossroads remains close enough for easy access. Discover the best value for your Lewis Crossroads stay with a hotel that won’t disappoint—reserve now!

  Call (855) 235-6136 to book with an agent.
  11.6 miles from Lewis Crossroads, SC 29550

Starting at

$118.99

per night

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Howard Johnson by Wyndham Florence

2038 West Lucas Street Florence, SC

For budget-conscious guests visiting Lewis Crossroads, Howard Johnson by Wyndham Florence offers plush accommodations with rates starting at $79.99, creating a warm and welcoming environment. Learn about our sustainability efforts, which aim to minimize environmental impact while maintaining comfort and convenience.

For guests seeking both tranquility and city access, Howard Johnson by Wyndham Florence offers the best of both worlds, with downtown Lewis Crossroads within reach. Experience Lewis Crossroads with added comfort and savings—reserve your hotel today!

  Call (855) 233-7850 to book with an agent.
  11.6 miles from Lewis Crossroads, SC 29550

Starting at

$79.99

per night

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Country Inn & Suites by Radisson Florence SC

1739 Mandeville Rd Florence, SC

With rates starting at $150.99, Country Inn & Suites by Radisson Florence SC is ideal for guests bound for Lewis Crossroads, providing sheltered accommodations in a warm, inviting setting. Appreciate the family-friendly atmosphere at Country Inn & Suites, with accommodations and services designed to make everyone feel welcome.

For a relaxing getaway, Country Inn & Suites by Radisson Florence SC provides calm surroundings while keeping downtown Lewis Crossroads within easy reach for exploration. Rest easy in Lewis Crossroads with a hotel that prioritizes your relaxation and budget—book today!

  Call (855) 234-5074 to book with an agent.
  11.6 miles from Lewis Crossroads, SC 29550

Starting at

$150.99

per night

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Park Inn by Radisson Florence SC

1729 Mandeville Road Florence, SC

For a comfortable stay, Park Inn by Radisson Florence SC offers budget-friendly rooms with rates beginning at $128.99, creating a clean and inviting space ideal for relaxation. Benefit from Radisson's business centers, providing all the tools and services necessary for the modern professional on the move.

Travelers can unwind in the peaceful atmosphere of Park Inn by Radisson Florence SC, while the attractions of downtown Lewis Crossroads are a quick drive away. Choose a hotel that brings comfort and affordability together in Lewis Crossroads—book now!

  Call (855) 234-2997 to book with an agent.
  11.7 miles from Lewis Crossroads, SC 29550

Starting at

$128.99

per night

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Motel 6 Florence SC

2004 West Lucas St Florence, SC

At Motel 6 Florence SC, travelers bound for Lewis Crossroads can unwind in budget-friendly rooms with rates beginning at $54.99, creating a tucked away, inviting atmosphere. Navigate the local area with recommendations from Motel 6's friendly staff, who are always ready to help you discover nearby gems.

Relax in the peaceful surroundings of Motel 6 Florence SC, with downtown Lewis Crossroads remaining within reach for a day of city adventure. Make your Lewis Crossroads experience enjoyable and budget-friendly—lock in now!

  Call (855) 239-4019 to book with an agent.
  11.8 miles from Lewis Crossroads, SC 29550

Starting at

$54.99

per night

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Econo Lodge

1916 West Lucas St Florence, SC

For guests traveling to Lewis Crossroads, Econo Lodge provides affordable comfort with rooms beginning at $56.99, creating a warm and inviting atmosphere perfect for rest. Trust in Econo Lodge for a reliable stay, where essential amenities and comfortable accommodations ensure a pleasant visit.

Relax in the serene surroundings of Econo Lodge, with the excitement of downtown Lewis Crossroads still a convenient drive away. Make the most of your Lewis Crossroads travels with affordable, welcoming accommodations—book now!

  Call (855) 239-5277 to book with an agent.
  11.9 miles from Lewis Crossroads, SC 29550

Starting at

$56.99

per night

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Suburban Studios Florence I-95

1914 West Lucas St Florence, SC

Guests bound for Lewis Crossroads can unwind at Suburban Studios Florence I-95, where budget-friendly rooms start at $56.99, providing a warm and comfortable space ideal for a restful stay. Find a comfortable base for your travels in rooms that offer essential amenities and straightforward service.

For a restful stay, Suburban Studios Florence I-95 offers quiet surroundings with the convenience of downtown Lewis Crossroads still being within easy reach. Stay affordably and enjoy extra amenities on your Lewis Crossroads trip—lock in now!

  Call (855) 233-0132 to book with an agent.
  11.9 miles from Lewis Crossroads, SC 29550

Starting at

$56.99

per night

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Homewood Suites by Hilton Florence

3450 West Radio Drive Florence, SC

Enjoy a homely retreat at Homewood Suites by Hilton Florence as you travel to Lewis Crossroads, where welcoming rooms provide comfort and value, with affordable rates starting at $156.99 per night. Relax with in-suite massage services at Homewood Suites, a perfect indulgence during your extended stay.

For a peaceful retreat, Homewood Suites by Hilton Florence offers quiet surroundings, with the added convenience of downtown Lewis Crossroads being nearby. Find out how stress-free Lewis Crossroads travel can be with thoughtfully designed accommodations—book today!

  Call (855) 234-7135 to book with an agent.
  12.0 miles from Lewis Crossroads, SC 29550

Starting at

$156.99

per night

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Quality Inn&Suites Civic

150 Dunbarton Dr Florence, SC

With budget-conscious rooms starting at $95.99, Quality Inn&Suites Civic is a practical option for travelers to Lewis Crossroads, providing a welcoming space ideal for relaxation. Stay energized with Quality Inn's complimentary coffee stations, available 24/7 in the lobby for a quick pick-me-up.

For a restful stay, Quality Inn&Suites Civic provides peaceful surroundings, with downtown Lewis Crossroads still a comfortable drive away. Maximize your time in Lewis Crossroads with lodging that keeps your comfort top of mind—lock in today!

  Call (855) 239-5277 to book with an agent.
  12.0 miles from Lewis Crossroads, SC 29550

Starting at

$95.99

per night

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Baymont Inn & Suites Florence by Wyndham

1826 West Lucas Street Florence, SC

Guests bound for Lewis Crossroads can enjoy affordable comfort at Baymont Inn & Suites Florence by Wyndham, where warm rooms start at $43.99, creating a warm and inviting atmosphere for relaxation. Experience a sense of community at Baymont by Wyndham, where the lobby serves as a gathering space for guests to meet and mingle.

The tranquil setting at Baymont Inn & Suites Florence by Wyndham offers a relaxing stay, with downtown Lewis Crossroads still accessible for a day of exploration. Get ready to enjoy Lewis Crossroads with accommodations that balance cost and comfort—lock in today!

  Call (855) 233-7850 to book with an agent.
  12.0 miles from Lewis Crossroads, SC 29550

Starting at

$43.99

per night

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MainStay Suites

1819 West Lucas St. Building B Florence, SC

For a comfortable and inviting stay, MainStay Suites offers inviting rooms with rates beginning at $56.99, creating a clean and comfortable space near Lewis Crossroads. Appreciate the peace of mind with secure parking facilities at MainStay Suites, ensuring your vehicle is safe during your stay.

For those looking to unwind after a day in downtown Lewis Crossroads, MainStay Suites offers a calm retreat that’s just a comfortable drive away. Rest assured knowing your Lewis Crossroads trip will be cozy and budget-conscious—book your room today!

  Call (855) 234-5074 to book with an agent.
  12.0 miles from Lewis Crossroads, SC 29550

Starting at

$56.99

per night

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Clarion Inn & Suites

1819 West Lucas Street Florence, SC

At Clarion Inn & Suites, guests bound for Lewis Crossroads can enjoy affordable accommodations with rooms beginning at $47.99, creating a warm, inviting atmosphere for relaxation. Experience the convenience of onsite laundry facilities at Clarion Inn, ideal for long stays or when you need fresh clothes in a hurry.

With downtown Lewis Crossroads just a drive away, Clarion Inn & Suites offers the perfect place to relax after a day of exploration. Make every moment in Lewis Crossroads memorable with a hotel that fits your budget—reserve today!

  Call (855) 234-2997 to book with an agent.
  12.0 miles from Lewis Crossroads, SC 29550

Starting at

$47.99

per night

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Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence, SC

Guests visiting Lewis Crossroads will appreciate the homely comfort at Days Inn by Wyndham Florence Near Civic Center, where rooms begin at $78.99, creating a welcoming and inviting environment. Appreciate the added value of Days Inn's amenities, including on-site laundry facilities at select locations for guest convenience.

For travelers seeking peace and quiet, Days Inn by Wyndham Florence Near Civic Center provides a serene retreat with downtown Lewis Crossroads still nearby for exploration. Find the perfect Lewis Crossroads escape with accommodations that don’t break the bank—lock in today!

  Call (855) 235-6136 to book with an agent.
  12.0 miles from Lewis Crossroads, SC 29550

Starting at

$78.99

per night

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Super 8 by Wyndham Florence

1832 1 / 2 Lucas St. I95 Exit 164 Florence, SC

For guests headed to Lewis Crossroads, Super 8 by Wyndham Florence provides inviting accommodations with rooms starting at $68.99, creating a warm and welcoming atmosphere for relaxation. Retire to Super 8’s cozy rooms after a day of activities, where you’ll find all the essentials for winding down and recharging.

From Super 8 by Wyndham Florence, a brief drive into downtown Lewis Crossroads allows guests to enjoy the best of both worlds—city exploration and a peaceful retreat afterward. Choose a cost-effective, welcoming hotel for your Lewis Crossroads visit—book now!

  Call (855) 236-8982 to book with an agent.
  12.1 miles from Lewis Crossroads, SC 29550

Starting at

$68.99

per night

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