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Top 24 Hotels In Lake City, South Carolina 29560

The Inn at the Crossroads

128 West Main Street Lake City, SC

At The Inn at the Crossroads, guests traveling to Lake City can enjoy affordable rooms starting at $169.99, providing a alluring, inviting environment ideal for relaxation. Experience a comfortable stay with rooms that provide practical comfort, ensuring a pleasant visit at a great price.

The Inn at the Crossroads provides a convenient location for travelers who want to explore Lake City, with the city center’s most popular destinations just a short stroll away. Enjoy Lake City adventures without the expense—book your inviting, cost-effective stay now!

  Call (855) 233-0132 to book with an agent.
  0.4 miles from Lake City, SC 29560

Starting at

$169.99

per night

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Days Inn by Wyndham Lake City

170 South Ron Mcnair Blvd Lake City, SC

For travelers headed to Lake City, Days Inn by Wyndham Lake City provides inviting accommodations with rooms starting at $137.99, creating a warm and comfortable environment. Navigate your trip with ease, thanks to Days Inn's central locations and accessibility to public transportation.

At Days Inn by Wyndham Lake City, you’re never far from Lake City’s most exciting attractions, where the downtown area’s top spots are just minutes away. Lock in an affordable hotel with extra comfort for your Lake City trip—reserve now!

  Call (855) 233-7850 to book with an agent.
  0.6 miles from Lake City, SC 29560

Starting at

$137.99

per night

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Quality Inn & Suites

202 North Ron Mcnair Blvd Lake City, SC

Guests visiting Lake City will find harmonious comfort at Quality Inn & Suites, with inviting rooms starting at $134.99, creating a welcoming atmosphere ideal for rest. Indulge in a culinary treat with Quality Inn's themed dinner nights, featuring dishes from around the world.

With easy access to downtown Lake City, guests at Quality Inn & Suites can enjoy the city’s top spots while retreating to a peaceful setting at the end of the day. Relax in Lake City at a hotel that knows how to make your stay special—lock in today!

  Call (855) 236-8982 to book with an agent.
  0.8 miles from Lake City, SC 29560

Starting at

$134.99

per night

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Security Inn & suites

319 Sumter St Lake City, SC

Guests bound for Lake City will find restorative accommodations at Security Inn & suites, with rooms starting at $123.99, creating a warm and inviting atmosphere perfect for a peaceful stay. Enjoy standard amenities in rooms designed to offer a worry-free stay, ensuring a pleasant visit at a great price.

Security Inn & suites provides guests with a convenient location, where Lake City’s bustling downtown is just a short walk or ride from the hotel. Book a practical and comfortable stay for your Lake City travels—secure today!

  Call (855) 234-7135 to book with an agent.
  0.9 miles from Lake City, SC 29560

Starting at

$123.99

per night

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Quality Inn Kingstree

1610 North Longstreet St Kingstree, SC

With budget-friendly rooms beginning at $79.99, Quality Inn Kingstree provides inviting comfort for travelers bound for Lake City, creating a warm and welcoming space. Stay productive with Quality Inn's business centers, complete with computers, printers, and high-speed internet access.

For a restful stay, Quality Inn Kingstree offers quiet surroundings with the convenience of downtown Lake City still being within easy reach. Experience Lake City the way you deserve with budget-savvy, comfortable lodging—book now!

  Call (855) 233-0132 to book with an agent.
  13.4 miles from Lake City, SC 29560

Starting at

$79.99

per night

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Bellas Boutique Hotel

111 North Main St Hemingway, SC

With affordable rooms beginning at $65.99, Bellas Boutique Hotel provides budget-conscious accommodations for travelers headed to Lake City, creating a warm, welcoming environment. Relax in well-maintained accommodations that offer the essentials for a comfortable and affordable stay.

For a restful stay, Bellas Boutique Hotel offers quiet surroundings with downtown Lake City remaining nearby for easy access to city attractions. Enjoy Lake City with a hotel that keeps your comfort and budget in mind—reserve today!

  Call (855) 233-0132 to book with an agent.
  19.2 miles from Lake City, SC 29560

Starting at

$65.99

per night

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Super 8 by Wyndham Florence SC I-95 North / Hwy 76

3783A West Palmetto Street Florence, SC

Guests visiting Lake City will appreciate the warm-hearted comfort at Super 8 by Wyndham Florence SC I-95 North / Hwy 76, where budget-friendly rooms start at $50.99, creating a warm and inviting space. Indulge in Super 8’s varied breakfast options, designed to offer a satisfying start to your day with both hot and cold items.

Find a peaceful hideaway at Super 8 by Wyndham Florence SC I-95 North / Hwy 76, where you can unwind after exploring the bustling streets of Lake City. Book a practical, inviting hotel for your Lake City adventure and save—secure now!

  Call (855) 239-4019 to book with an agent.
  21.1 miles from Lake City, SC 29560

Starting at

$50.99

per night

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Aloft Florence

820 WOODY JONES BOULEVARD Florence, SC

Stay affordably at Aloft Florence on your visit to Lake City, where inviting accommodations create a warm environment, with room rates starting at $154.99. Experience the personalized service of Aloft's dedicated hosts, ensuring your stay is tailored to your needs and preferences.

At Aloft Florence, you’ll find the ideal base for rest and relaxation, with the vibrant life of Lake City nearby for exploration. Stay in Lake City with a hotel that brings relaxation and affordability together—secure now!

  Call (855) 234-7135 to book with an agent.
  22.4 miles from Lake City, SC 29560

Starting at

$154.99

per night

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Fairfield Inn & Suites by Marriott Florence I-20

501 Woody Jones Boulevard Florence, SC

Guests traveling to Lake City will find Fairfield Inn & Suites by Marriott Florence I-20 a tucked away, budget-friendly option, with rooms beginning at $179.99, creating a welcoming atmosphere perfect for rest. Experience the convenience and taste of Fairfield's 24/7 market, stocked with a selection of snacks, beverages, and quick meals.

Find your ideal retreat at Fairfield Inn & Suites by Marriott Florence I-20, a calming spot that’s just a short drive away from the vibrant streets of Lake City. Step into a welcoming Lake City stay that delivers on both comfort and savings—lock in today!

  Call (855) 235-6136 to book with an agent.
  22.4 miles from Lake City, SC 29560

Starting at

$179.99

per night

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Comfort Inn & Suites

527 Woody Jones Blvd Florence, SC

At Comfort Inn & Suites, guests traveling to Lake City can enjoy budget-friendly rooms starting at $128.99, creating a warm and welcoming space perfect for unwinding. Trust in Comfort Inn for a straightforward and satisfying stay, with no hidden fees and a focus on your overall well-being.

At Comfort Inn & Suites, guests can enjoy both relaxation and proximity to Lake City, offering the perfect combination for a balanced stay. Experience Lake City the way you deserve with budget-savvy, comfortable lodging—book now!

  Call (855) 234-7135 to book with an agent.
  22.4 miles from Lake City, SC 29560

Starting at

$128.99

per night

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Home2 Suites by Hilton Florence SC

900 Woody Jones Blvd Florence, SC

Discover a relaxing stay at Home2 Suites by Hilton Florence SC near Lake City, with comfortable rooms offering restful accommodations, with rates starting at $138.99 per night. Stay healthy with Home2 Suites' filtered water stations, available in gyms and public areas to keep you hydrated and refreshed.

Step into comfort at Home2 Suites by Hilton Florence SC, a peaceful retreat where guests can relax and still venture into Lake City for excitement. Enjoy a Lake City adventure with a hotel that’s committed to your satisfaction—book today!

  Call (855) 233-0132 to book with an agent.
  22.4 miles from Lake City, SC 29560

Starting at

$138.99

per night

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Homewood Suites by Hilton Florence

3450 West Radio Drive Florence, SC

Homewood Suites by Hilton Florence offers a relaxing option for travelers visiting Lake City, with comfortable accommodations starting at a welcoming $156.99 per night. Enjoy the luxury of heated bathroom floors in select suites at Homewood Suites, adding comfort to your morning routine.

Positioned just outside Lake City, Homewood Suites by Hilton Florence ensures guests can recharge while keeping urban adventures close by. Enjoy exceptional value and superior comfort during your Lake City visit—lock in today!

  Call (855) 235-0725 to book with an agent.
  22.5 miles from Lake City, SC 29560

Starting at

$156.99

per night

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TownePlace Suites by Marriott Florence

2650 Hospitality Boulevard Florence, SC

With budget-conscious rooms starting at $204.99, TownePlace Suites by Marriott Florence is an ideal choice for travelers to Lake City, creating a homely, welcoming space perfect for rest. Navigate your destination confidently with recommendations and assistance from TownePlace Suites' knowledgeable staff.

Find your peaceful getaway at TownePlace Suites by Marriott Florence, where you can unwind in quiet comfort while Lake City's attractions are never far away. Enjoy a seamless Lake City experience with amenities designed for your convenience—reserve now!

  Call (855) 239-4019 to book with an agent.
  22.5 miles from Lake City, SC 29560

Starting at

$204.99

per night

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Hyatt Place Florence Downtown

100 East Evans St. Florence Florence, SC

Relax at Hyatt Place Florence Downtown on your journey to Lake City, where comforting accommodations create a peaceful escape, with inviting nightly rates starting from $179.00. Forget something? Hyatt Place's Odds & Ends service has you covered with essential travel items and more, available for purchase or borrow.

At Hyatt Place Florence Downtown, guests can enjoy both peaceful surroundings and the ease of exploring Lake City whenever they wish. Stay affordably in Lake City with a hotel that makes quality and savings a priority—lock in today!

  Call (855) 239-5277 to book with an agent.
  22.5 miles from Lake City, SC 29560

Starting at

$179.00

per night

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Residence Inn Marriott Florence

2660 Hospitality Blvd Florence, SC

Find a welcoming atmosphere at Residence Inn Marriott Florence on your journey to Lake City, where alluring rooms offer quality and comfort, with rates starting at $214.99. Take advantage of the free grocery delivery service at Residence Inn, simplifying your meal preparations during your stay.

Relax and recharge at Residence Inn Marriott Florence, offering a quiet setting that ensures restful nights with Lake City's attractions nearby. Choose a Lake City hotel that transforms your visit with well-rounded, inviting amenities—lock in today!

  Call (855) 234-5074 to book with an agent.
  22.5 miles from Lake City, SC 29560

Starting at

$214.99

per night

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Hilton Garden Inn Florence

2671 Hospitality Boulevard Florence, SC

With budget-conscious rooms from $125.99, Hilton Garden Inn Florence provides warm accommodations for guests bound for Lake City, creating a clean, comfortable space. Relax and refresh in Hilton Garden Inn's Swimming Pool, the perfect place to start your morning with a swim or unwind at the end of the day.

Relax in the quiet comfort of Hilton Garden Inn Florence, while keeping Lake City's attractions within easy reach whenever you desire. Enjoy your Lake City adventure with lodging that makes every penny worth it—secure your room now!

  Call (855) 233-0132 to book with an agent.
  22.6 miles from Lake City, SC 29560

Starting at

$125.99

per night

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Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel

3440 West Radio Dr Florence, SC

With rooms starting at $144.00, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel provides budget-friendly comfort for travelers bound for Lake City, creating a clean, welcoming environment. Stay connected with Holiday Inn Express's business centers, offering printing, faxing, and scanning services.

Guests seeking calm surroundings will enjoy Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel, a peaceful haven with easy access to Lake City's top destinations. Rest easy in Lake City with a hotel that prioritizes your relaxation and budget—book today!

  Call (855) 234-2997 to book with an agent.
  22.6 miles from Lake City, SC 29560

Starting at

$144.00

per night

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Staybridge Suites Florence Civic Center an IHG Hotel

150 Westpark Drive Florence, SC

Find a warm retreat at Staybridge Suites Florence Civic Center an IHG Hotel on your journey to Lake City, where inviting rooms create a welcoming environment, with nightly rates from $194.00. Find solace in Staybridge Suites' outdoor seating areas, offering a calm space to enjoy a cup of coffee or a good book.

Find your ideal getaway at Staybridge Suites Florence Civic Center an IHG Hotel, where calm surroundings and the convenience of Lake City come together seamlessly. Take your Lake City adventure to new heights with a hotel that provides exceptional service—secure now!

  Call (855) 236-8982 to book with an agent.
  22.6 miles from Lake City, SC 29560

Starting at

$194.00

per night

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Red Roof Inn Florence Civic Center

2690 David H McLeod Boulevard Florence, SC

For a comfortable and budget-friendly stay, Red Roof Inn Florence Civic Center offers relaxed rooms with rates from $69.00, creating a welcoming, clean environment near Lake City. Stay connected throughout your travels with Red Roof Inn’s complimentary high-speed Wi-Fi, perfect for both business and leisure guests.

Guests at Red Roof Inn Florence Civic Center can experience the charm of a peaceful retreat while remaining close enough to explore Lake City. Enjoy Lake City with a hotel that keeps your comfort and budget in mind—reserve today!

  Call (855) 235-0725 to book with an agent.
  22.7 miles from Lake City, SC 29560

Starting at

$69.00

per night

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Courtyard by Marriott Florence

2680 Hospitality Blvd Florence, SC

Enjoy the sheltered ambiance of Courtyard by Marriott Florence when traveling to Lake City, where inviting rooms offer relaxation, with rates beginning at just $149.99 per night. Hydrate healthily with Courtyard's infused water stations, offering refreshing, flavored water options throughout the hotel.

Unwind in comfort at Courtyard by Marriott Florence, where guests can rest in quiet surroundings and still enjoy the convenience of Lake City. Relax in a Lake City hotel that turns your trip into a delightful experience—lock in today!

  Call (855) 234-5074 to book with an agent.
  22.7 miles from Lake City, SC 29560

Starting at

$149.99

per night

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SpringHill Suites by Marriott Florence

2670 Hospitality Blvd Florence, SC

Stay at SpringHill Suites by Marriott Florence for a restful visit to Lake City, where quiet accommodations create a welcoming environment, with affordable rates starting at just $152.99. Appreciate the versatility of SpringHill Suites' accommodations, suitable for solo travelers, couples, families, and business guests alike.

At SpringHill Suites by Marriott Florence, enjoy a calming escape, perfect for those looking to explore Lake City without staying in the middle of the action. Step into Lake City with a hotel that makes every detail of your stay seamless—reserve your room now!

  Call (855) 234-2997 to book with an agent.
  22.7 miles from Lake City, SC 29560

Starting at

$152.99

per night

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Hotel Florence Tapestry Collection by Hilton

126 West Evans St Florence, SC

Experience a delightful retreat at Hotel Florence Tapestry Collection by Hilton as you explore Lake City, where restful accommodations await at a starting rate of $163.99 per night. Engage with nature on the trails and paths surrounding Tapestry Collection hotels, perfect for morning runs or leisurely walks.

At Hotel Florence Tapestry Collection by Hilton, guests can experience a relaxing stay while enjoying easy access to Lake City’s exciting attractions. Choose a hotel in Lake City that brings your travel experience to life—reserve your stay now!

  Call (855) 234-5074 to book with an agent.
  22.8 miles from Lake City, SC 29560

Starting at

$163.99

per night

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Hampton Inn & Suites Florence Center

3000 West Radio Dr Florence, SC

At Hampton Inn & Suites Florence Center, travelers headed to Lake City will find inviting accommodations with rooms starting at $151.99, creating a clean and comfortable space. Rely on the consistent quality and service that Hampton by Hilton offers, where you can expect the same high standards at any location.

At Hampton Inn & Suites Florence Center, guests can recharge in peaceful surroundings and still have the option to explore the sights of Lake City. Uncover value-driven comfort that makes Lake City travel easy—book your stay today!

  Call (855) 234-7135 to book with an agent.
  22.8 miles from Lake City, SC 29560

Starting at

$151.99

per night

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Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence, SC

With rates beginning at $78.99, Days Inn by Wyndham Florence Near Civic Center is an ideal choice for budget-savvy travelers to Lake City, creating a warm and inviting space. Refresh and recharge in Days Inn's clean, well-maintained guest rooms, focusing on your comfort and satisfaction.

Stay at Days Inn by Wyndham Florence Near Civic Center for a blend of relaxation and exploration, with calm lodgings close to Lake City for easy day trips. Maximize your Lake City adventure with thoughtfully designed, affordable lodging—secure your room now!

  Call (855) 235-6136 to book with an agent.
  22.9 miles from Lake City, SC 29560

Starting at

$78.99

per night

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