The best deals on hotels when visiting Anniston in Missouri.

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Top 24 Hotels In Anniston, Missouri 63820

Quality Inn Charleston Sikeston

102 Drake St Charleston, MO

With budget-friendly rooms from $71.99, Quality Inn Charleston Sikeston is ideal for travelers visiting Anniston, creating a warm and inviting environment for relaxation. Appreciate the boutique atmosphere of Quality Inn's individually decorated rooms, each with unique design features and local flair.

With downtown Anniston still within reach, guests at Quality Inn Charleston Sikeston can enjoy the best of both worlds—easy city access and a more relaxed atmosphere. Unwind in Anniston with accommodations that blend affordability and relaxation—book today!

  Call (855) 235-0725 to book with an agent.
  5.9 miles from Anniston, MO 63820

Starting at

$71.99

per night

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Super 8 by Wyndham Charleston / Sikeston East MO

310 South Story St Charleston, MO

At Super 8 by Wyndham Charleston / Sikeston East MO, travelers bound for Anniston can enjoy budget-conscious comfort with rooms starting at $59.99, creating a warm, inviting environment for rest. Navigate with ease, as Super 8 often features locations that provide quick access to local highways and popular tourist spots.

At Super 8 by Wyndham Charleston / Sikeston East MO, guests can relax in a quieter environment, with downtown Anniston still within easy reach for a day of exploring. Stay affordably and experience added perks on your Anniston trip—reserve your room now!

  Call (855) 235-0725 to book with an agent.
  6.6 miles from Anniston, MO 63820

Starting at

$59.99

per night

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Eagle Inn Charleston

2811 East Marshall Street Charleston, MO

For those traveling to Anniston, Eagle Inn Charleston offers soft comfort with rooms beginning at $69.29, creating a clean and inviting atmosphere ideal for rest. Enjoy the essentials in well-maintained rooms that provide a comfortable and affordable environment for your visit.

Guests staying at Eagle Inn Charleston will appreciate the calm environment, with downtown Anniston still accessible by car for a day of city exploration. Make your Anniston trip enjoyable and economical—secure your hotel stay today!

  Call (855) 233-0132 to book with an agent.
  6.8 miles from Anniston, MO 63820

Starting at

$69.29

per night

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Days Inn&Suites by Wyndham Sikeston

220 South Interstate Dr Sikeston, MO

At Days Inn&Suites by Wyndham Sikeston, travelers to Anniston can enjoy inviting accommodations with rooms from $74.99, creating a clean and comfortable atmosphere perfect for unwinding. Relax with a peace of mind provided by our round-the-clock security measures, ensuring a safe environment for all guests.

Guests at Days Inn&Suites by Wyndham Sikeston will appreciate the calm environment, while the energy of downtown Anniston remains easily accessible. Choose comfort and affordability for your Anniston stay—book your room today!

  Call (855) 235-6136 to book with an agent.
  12.1 miles from Anniston, MO 63820

Starting at

$74.99

per night

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Country Yard Inn&Suite

110 South Interstate Drive Sikeston, MO

With rooms beginning at $55.99, Country Yard Inn&Suite offers budget-friendly accommodations for travelers bound for Anniston, creating a calm, comfortable space. Find comfort in rooms that provide dependable amenities, ensuring a pleasant stay at a great price.

At Country Yard Inn&Suite, guests can unwind in a calm environment while knowing that downtown Anniston remains within easy reach. Choose affordability and extra perks for your Anniston travels—book your hotel now!

  Call (855) 235-0725 to book with an agent.
  12.2 miles from Anniston, MO 63820

Starting at

$55.99

per night

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Best Western Plus Sikeston

120 South Interstate Drive Sikeston, MO

At Best Western Plus Sikeston, travelers bound for Anniston can enjoy restful accommodations with rooms starting at $92.99, creating a clean and comfortable space perfect for rest. Appreciate the 24-hour reception at Best Western Plus, where friendly staff are available to assist you at any time of day or night.

Enjoy the quiet surroundings at Best Western Plus Sikeston, where downtown Anniston remains accessible by car for a day of sightseeing and adventure. Take the guesswork out of your Anniston stay with a hotel that delivers on value—secure now!

  Call (855) 234-7135 to book with an agent.
  12.2 miles from Anniston, MO 63820

Starting at

$92.99

per night

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Travel Inn & Suites Sikeston / Miner (i-55 Exit 67)

100 Matthews Lane Sikeston, MO

With rates beginning at $68.99, Travel Inn & Suites Sikeston / Miner (i-55 Exit 67) is an ideal choice for budget-savvy travelers to Anniston, creating a warm and inviting space. Find a cozy and affordable stay in rooms that provide a comfortable sleeping environment and basic conveniences.

Guests staying at Travel Inn & Suites Sikeston / Miner (i-55 Exit 67) can enjoy a quiet retreat, with downtown Anniston still within reach for all their city adventures. Enjoy a seamless Anniston experience with lodging that doesn’t compromise on comfort—book now!

  Call (855) 236-8982 to book with an agent.
  12.4 miles from Anniston, MO 63820

Starting at

$68.99

per night

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Comfort Inn & Suites Sikeston I-55

109 Matthews Ln Sikeston, MO

With rooms beginning at $106.99, Comfort Inn & Suites Sikeston I-55 provides budget-friendly comfort for travelers bound for Anniston, creating a intimate and welcoming atmosphere. Navigate your travels with ease, thanks to local recommendations and insights from Comfort Inn's knowledgeable staff.

Escape the rush of downtown Anniston and retreat to the calm at Comfort Inn & Suites Sikeston I-55, where tranquility and easy access combine for the perfect stay. Choose a hotel that enhances your Anniston experience with thoughtful amenities—book today!

  Call (855) 233-7850 to book with an agent.
  12.5 miles from Anniston, MO 63820

Starting at

$106.99

per night

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Super 8 by Wyndham Sikeston / Miner Area

2609 East Malone Ave Sikeston, MO

Guests bound for Anniston will find budget-conscious comfort at Super 8 by Wyndham Sikeston / Miner Area, with warm-hearted rooms starting at $60.99, creating a clean, inviting environment for relaxation. Discover the ease of travel with Super 8's prime locations, conveniently close to major roads and local attractions.

Guests at Super 8 by Wyndham Sikeston / Miner Area can enjoy quiet surroundings, with the added convenience of downtown Anniston being just a drive away. Lock in a cozy, affordable stay perfect for your Anniston adventure—reserve now!

  Call (855) 239-5277 to book with an agent.
  12.6 miles from Anniston, MO 63820

Starting at

$60.99

per night

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Hampton Inn Sikeston

1240 Commerce Drive Sikeston, MO

Guests traveling to Anniston will find affordable comfort at Hampton Inn Sikeston, where gentle rooms start at $126.99, creating a warm, inviting space ideal for unwinding. Adjust your room’s climate to your preference with Hampton’s individual air conditioning units, ensuring comfort in any weather.

At Hampton Inn Sikeston, the quiet surroundings create a peaceful retreat, while the excitement of downtown Anniston is just a drive away. Relax and unwind in Anniston with a hotel that prioritizes your comfort—book your room today!

  Call (855) 235-0725 to book with an agent.
  14.2 miles from Anniston, MO 63820

Starting at

$126.99

per night

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Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel

115 Hospitality Dr Sikeston, MO

With affordable rooms from $144.00, Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel provides inviting comfort for travelers to Anniston, creating a clean, welcoming space perfect for relaxation. Refresh and recharge in Holiday Inn Express's stylish and functional bathrooms, equipped with powerful showers and quality toiletries.

Enjoy the quiet surroundings at Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel, where downtown Anniston remains accessible by car for a day of sightseeing and adventure. Choose a hotel that complements your Anniston plans with ease and affordability—secure now!

  Call (855) 234-5074 to book with an agent.
  14.3 miles from Anniston, MO 63820

Starting at

$144.00

per night

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Quality Inn Cairo I-57

13201 Kessler Road Cairo, IL

For an affordable stay near Anniston, Quality Inn Cairo I-57 offers inviting rooms with rates starting at $80.99, creating a clean and welcoming space ideal for rest. Enjoy a seamless stay with Quality Inn's express services, including fast check-in and check-out to accommodate your schedule.

For travelers looking for peace, Quality Inn Cairo I-57 offers quiet surroundings while keeping downtown Anniston just a convenient drive away. Stay affordably and rest well in Anniston with a hotel that understands your needs—secure now!

  Call (855) 236-8982 to book with an agent.
  16.6 miles from Anniston, MO 63820

Starting at

$80.99

per night

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La Center Motel

474 West Kentucky Dr La Center, KY

With affordable rooms starting at $65.99, La Center Motel provides budget-conscious comfort for guests visiting Anniston, creating a welcoming and relaxing space. Experience a comfortable stay with rooms that provide practical amenities, making your visit both enjoyable and economical.

At La Center Motel, the peaceful atmosphere offers guests a restful stay while keeping the attractions of Anniston close by. Stay budget-wise while enjoying Anniston in comfort—secure your hotel today!

  Call (855) 235-0725 to book with an agent.
  25.7 miles from Anniston, MO 63820

Starting at

$65.99

per night

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Travel Inn

301 Route Ad Marston, MO

For an inviting and affordable stay, Travel Inn offers budget-friendly rooms with rates starting at $57.91, creating a clean and comfortable space. Experience a stay that meets your essential needs, with rooms that are clean, comfortable, and conveniently equipped.

Step into the calm of Travel Inn, where quiet rooms are paired with the excitement of Anniston just a short drive away. Embrace a worry-free Anniston adventure with practical, inviting lodging—reserve your room now!

  Call (855) 235-0725 to book with an agent.
  26.3 miles from Anniston, MO 63820

Starting at

$57.91

per night

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Holiday Inn Express & Suites Union City an IHG Hotel

810 BREAM BOULEVARD Union City, TN

With budget-friendly rooms beginning at $125.00, Holiday Inn Express & Suites Union City an IHG Hotel is ideal for guests traveling to Anniston, creating a comfortable, welcoming space for rest. Appreciate the modern touches at Holiday Inn Express, including keyless entry and motion-sensor lighting in guest rooms.

Guests at Holiday Inn Express & Suites Union City an IHG Hotel will appreciate the calm surroundings, with Anniston's vibrant offerings only a short drive away. Enjoy Anniston without compromise with a hotel that delivers exceptional value—reserve now!

  Call (855) 235-0725 to book with an agent.
  30.1 miles from Anniston, MO 63820

Starting at

$125.00

per night

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Sleep Inn

1111 BLue Heron Lane Union City, TN

For a sheltered and affordable stay near Anniston, Sleep Inn offers comfortable accommodations with rates beginning at $98.99, providing a warm environment. Experience Sleep Inn's warm hospitality and attentive service, making you feel welcome from check-in to check-out.

Escape the urban buzz at Sleep Inn, offering peaceful lodgings just a short drive from the dynamic heart of Anniston. Discover a welcoming, cost-effective hotel perfect for your Anniston getaway—secure today!

  Call (855) 234-7135 to book with an agent.
  30.3 miles from Anniston, MO 63820

Starting at

$98.99

per night

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MainStay Suites

1111 Blue Heron Lane Building B Union City, TN

Guests traveling to Anniston will find comfy accommodations at MainStay Suites, where rooms begin at $106.99, creating a warm, inviting environment ideal for relaxation. Enjoy the social vibe of MainStay Suites’ weekly manager’s reception, featuring complimentary beverages and a chance to socialize.

Find calm and convenience at MainStay Suites, offering a tranquil setting and quick access to Anniston's popular attractions. Get ready for a comfortable Anniston adventure with cost-effective, inviting accommodations—lock in now!

  Call (855) 233-7850 to book with an agent.
  31.4 miles from Anniston, MO 63820

Starting at

$106.99

per night

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Hospitality House Union City US 51

1221 West Reelfoot Ave Union City, TN

Guests bound for Anniston will enjoy budget-conscious accommodations at Hospitality House Union City US 51, with rooms starting at $60.71, creating a welcoming space. Experience a more satisfying visit in accommodations that offer additional amenities and enhanced comfort.

Travelers will love the serene setting at Hospitality House Union City US 51, where peaceful accommodations offer a relaxing stay near Anniston. Get ready for a Anniston adventure with accommodations that keep your budget intact—book today!

  Call (855) 235-0725 to book with an agent.
  31.5 miles from Anniston, MO 63820

Starting at

$60.71

per night

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Quality Inn Union City US 51

2201 West Reelfoot Ave Union City, TN

With budget-friendly rooms beginning at $88.99, Quality Inn Union City US 51 is a practical choice for travelers to Anniston, creating a welcoming and comfortable space. Explore your destination with insider tips from Quality Inn's friendly staff, ready to point you to local attractions and eateries.

Take a break from the city noise at Quality Inn Union City US 51, offering restful accommodations and quick access to Anniston's best spots. Discover how stress-free Anniston can be with well-appointed, affordable lodging—book today!

  Call (855) 239-5277 to book with an agent.
  31.9 miles from Anniston, MO 63820

Starting at

$88.99

per night

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Hampton Inn Union City

2121 West REELFOOT AVE Union City, TN

At Hampton Inn Union City, travelers to Anniston will find budget-friendly rooms with rates beginning at $115.99, creating a welcoming, peaceful space perfect for rest. Kickstart your day with Hampton's complimentary hot breakfast, a hearty and healthy way to start your morning.

At Hampton Inn Union City, enjoy the peaceful environment and easy access to Anniston that make it an ideal destination for travelers. Discover a hotel that elevates your Anniston adventure while staying budget-friendly—reserve now!

  Call (855) 234-7135 to book with an agent.
  31.9 miles from Anniston, MO 63820

Starting at

$115.99

per night

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Regency Inn

128 CHEEKWOOD LN Ullin, IL

At Regency Inn, travelers bound for Anniston can unwind in budget-friendly rooms with rates beginning at $94.99, creating a serene, inviting atmosphere. Enjoy reliable comfort in rooms that provide everything you need for a worry-free visit at an economical price.

Unwind in the serene setting of Regency Inn, while knowing Anniston's lively streets are never too far away. Make your Anniston experience enjoyable without the high cost—reserve today!

  Call (855) 234-2997 to book with an agent.
  32.2 miles from Anniston, MO 63820

Starting at

$94.99

per night

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The Meadows Hotel

101 Commercial Avenue Fulton, KY

Those exploring Anniston will appreciate the warmth of The Meadows Hotel, where inviting accommodations create a peaceful escape, with rates from $139.99. Enjoy a premium stay with rooms that boast advanced technological amenities and elegant furnishings.

Discover your peaceful sanctuary at The Meadows Hotel, where the calm of your stay is enhanced by the proximity to Anniston's top spots. Discover how indulgent Anniston can be with a hotel that provides the ultimate experience—secure now!

  Call (855) 233-0132 to book with an agent.
  33.4 miles from Anniston, MO 63820

Starting at

$139.99

per night

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New Orleans Inn Portageville

600 US 61 Portageville, MO

At New Orleans Inn Portageville, travelers to Anniston will find budget-friendly rooms with rates beginning at $72.99, creating a welcoming, plush space perfect for rest. Relax in a functional space that offers a clean and comfortable setting, perfect for a short stay or a business trip.

Unwind in the comfort of New Orleans Inn Portageville, a peaceful escape where you can keep Anniston's energy within easy reach. Relax in Anniston with accommodations that make your stay unforgettable—secure now!

  Call (855) 236-8982 to book with an agent.
  34.0 miles from Anniston, MO 63820

Starting at

$72.99

per night

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Candlewood Suites Cape Girardeau an IHG Hotel

485 South Mount Auburn Rd Cape Girardeau, MO

For a welcoming and restful stay, Candlewood Suites Cape Girardeau an IHG Hotel offers inviting accommodations with rooms from $113.00, creating a restorative space ideal for travelers visiting Anniston. Unwind in the privacy of Candlewood Suites' suites, featuring separate living and sleeping areas for your comfort and convenience.

At Candlewood Suites Cape Girardeau an IHG Hotel, the quiet charm of the location is paired with the convenience of being near Anniston's vibrant offerings. Take advantage of Anniston travel with lodging that delivers exceptional value—book today!

  Call (855) 233-0132 to book with an agent.
  34.8 miles from Anniston, MO 63820

Starting at

$113.00

per night

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