Top 24 Hotels In Big Pine Key, Florida 33043

Guests traveling to Big Pine Key will find relaxed comfort at Parmers Resort, where rooms start at $134.99, providing a warm, welcoming environment perfect for relaxation. Find added comfort in accommodations that offer more amenities, creating a better experience at a great price.

At Parmers Resort, a quick drive brings guests into the lively downtown area of Big Pine Key, making it easy to explore the city’s best offerings. Get ready for a comfortable Big Pine Key adventure with cost-effective, inviting accommodations—lock in now!

Step into a realm of unparalleled sophistication at Isla Bella Beach Resort & Spa near Big Pine Key, where lavish rooms create a one-of-a-kind retreat, with rates from $264.99. Enjoy a stay that reflects meticulous craftsmanship, with rooms featuring detailed woodwork, luxurious textiles, and serene garden views.

Guests at Isla Bella Beach Resort & Spa can unwind in a tranquil setting, with the added benefit of downtown Big Pine Key being a convenient drive away. Awaken to a paradise of refinement in Big Pine Key with a hotel that caters to your dreams—book today!

Enjoy a peaceful stay at Captain Pips Marina & Hideaway on your journey to Big Pine Key, where inviting rooms provide comfort, with affordable rates beginning at $99.99 per night. Experience the best of both worlds with rooms that offer modern conveniences and traditional comfort.

A peaceful retreat awaits at Captain Pips Marina & Hideaway, while the excitement of downtown Big Pine Key is just a convenient drive away for exploration. Enjoy the best of Big Pine Key with a hotel that delivers quality service at a great price—reserve now!

Those exploring Big Pine Key will enjoy the refined luxury of Faro Blanco Resort & Yacht Club Marathon Curio by Hilton, where quality rooms promise rest and style, with affordable rates from $151.99. Indulge in the tranquility of Hilton's soundproof rooms, ensuring a peaceful and undisturbed rest no matter the location.

For those seeking tranquility, Faro Blanco Resort & Yacht Club Marathon Curio by Hilton provides a peaceful setting, while keeping downtown Big Pine Key easily accessible by car. Discover a Big Pine Key hotel that combines world-class amenities with a warm welcome—secure now!

Unwind at Courtyard by Marriott Faro Blanco Resort when traveling to Big Pine Key, where warm rooms provide a comfortable retreat, with inviting rates starting at $169.99 per night. Enjoy the casual atmosphere of Courtyard's afternoon social hour, featuring light refreshments in a relaxed, communal setting.

At Courtyard by Marriott Faro Blanco Resort, visitors can enjoy peaceful surroundings, knowing downtown Big Pine Key is still close enough for a day of sightseeing. Unwind in Big Pine Key with a hotel that offers a seamless blend of quality and savings—secure now!

Discover upscale refinement at Tranquility Bay Beachfront Hotel&Resort near Big Pine Key, where quality rooms create a luxurious setting, with budget-friendly rates starting at just $279.99. Relax in the lap of luxury, where rooms are designed to provide an indulgent experience with every modern convenience.

For those looking to unwind, Tranquility Bay Beachfront Hotel&Resort offers a quiet retreat, while the convenience of downtown Big Pine Key is within reach. Enjoy a Big Pine Key retreat that promises to impress from the moment you arrive—reserve your room now!

Experience quality and relaxation at Banana Bay Resort & Marina on your journey to Big Pine Key, where inviting rooms provide comfort, with nightly rates starting from $100.99. Experience a stay that combines the comforts of home with the conveniences of modern amenities, making your visit enjoyable.

For those looking to unwind, Banana Bay Resort & Marina offers a quiet retreat, while the convenience of downtown Big Pine Key is within reach. Take the hassle out of your Big Pine Key travels with a hotel that does it all—book today!

Relax in style at Aqua Lodges at 47th Street Gulfside as you visit Big Pine Key, where comfortable rooms create a charming retreat, with budget-friendly rates starting at $134.99. Enjoy a stay that prioritizes your comfort, with rooms equipped with thoughtful amenities to enhance your experience.

Guests at Aqua Lodges at 47th Street Gulfside will enjoy the calm atmosphere, while the convenience of downtown Big Pine Key remains just a short drive away. Get the most out of Big Pine Key with a hotel that enhances your travel experience—secure now!

Encounter hospitable accommodations at Skipjack Resort & Marina on your journey to Big Pine Key, where restful rooms create a welcoming environment, with rates beginning at $169.88. Experience thoughtful amenities and a comfortable setting, designed to make your stay both enjoyable and memorable.

For travelers seeking peace, Skipjack Resort & Marina offers a calm retreat with the convenience of downtown Big Pine Key still nearby. Stay comfortably in Big Pine Key with a hotel that offers all the perks you desire—book today!

Guests bound for Big Pine Key will appreciate the restorative comfort at Kingsail Resort, where budget-friendly rooms start at $101.99, creating a warm and welcoming atmosphere. Enjoy reliable comfort in rooms that provide everything you need for a worry-free visit at an economical price.

Relax in the quiet of Kingsail Resort, with the vibrant heart of downtown Big Pine Key still easily accessible by car for sightseeing. Enjoy Big Pine Key with an inviting hotel that balances comfort and savings—book now!

Guests visiting Big Pine Key can relax at Coconut Cay Resort & Marina, where affordable rooms begin at $132.99, creating a warm and welcoming environment ideal for relaxation. Relax in rooms that prioritize practical comfort and affordability, ensuring a pleasant and economical stay.

At Coconut Cay Resort & Marina, guests can unwind in quiet surroundings, while the energy of downtown Big Pine Key is just a drive away. Make your Big Pine Key trip enjoyable and cost-effective—reserve your hotel room now!

With rooms from $309.92, Siesta Motel offers budget-conscious accommodations for travelers headed to Big Pine Key, creating a intimate-feeling, comfortable environment for all guests. Experience a comfortable stay with rooms that offer the basics for a worry-free visit at a great price.

At Siesta Motel, visitors can unwind in peaceful surroundings, while downtown Big Pine Key remains a convenient drive away for a day of city adventures. Enjoy reliable, budget-friendly accommodations for your Big Pine Key travels—book now!

Unwind at Seascape Resort & Marina near Big Pine Key, where inviting rooms offer warmth and comfort, with budget-friendly nightly rates starting from just $251.99. Find comfort and convenience in our rooms, equipped with all the necessities for a stress-free and enjoyable stay.

Guests staying at Seascape Resort & Marina will appreciate the peaceful setting, with downtown Big Pine Key nearby for all their city adventures. Uncover Big Pine Key lodging that turns your trip into an unforgettable experience—secure now!

For those traveling to Big Pine Key, Bonefish Bay Motel offers affordable rooms with rates starting at $116.99, creating a clean, comfortable atmosphere ideal for rest. Enjoy a comfortable and welcoming environment in rooms that provide additional amenities for a relaxing visit.

With its perfect location, Bonefish Bay Motel offers guests the opportunity to experience both relaxation and city life near Big Pine Key. Experience Big Pine Key without overspending with a hotel that enhances your visit—lock in now!

With rates beginning at $149.99, Fairfield Inn & Suites by Marriott Marathon Florida Keys is ideal for guests visiting Big Pine Key, offering delightful accommodations in a welcoming, clean environment. Take a refreshing break in Fairfield’s tea lounges, offering a selection of herbal and traditional teas throughout the day.

Discover the balance of relaxation and adventure at Fairfield Inn & Suites by Marriott Marathon Florida Keys, where a peaceful stay is matched with proximity to Big Pine Key. Enjoy your Big Pine Key adventure with lodging that makes every penny worth it—secure your room now!

Guests visiting Big Pine Key can enjoy inviting accommodations at Hampton Inn Marathon Florida Keys, where budget-friendly rooms start at $136.99, creating a welcoming space. Explore with ease, knowing that Hampton by Hilton hotels are conveniently located near top local attractions and business centers.

Unwind in the comfort of Hampton Inn Marathon Florida Keys, where the restful ambiance ensures a peaceful stay with Big Pine Key always close by. Relax in Big Pine Key with accommodations that make your stay unforgettable—secure now!

Enjoy the peaceful surroundings of Glunz Ocean Beach Hotel & Resort near Big Pine Key, where quality rooms create a restful escape, with budget-friendly rates starting from $169.99. Experience a higher standard of comfort in rooms equipped with modern amenities, designed for both relaxation and efficiency.

Rest easy at Glunz Ocean Beach Hotel & Resort, a peaceful spot just outside Big Pine Key, perfect for unwinding after a day of exploration. Make your Big Pine Key adventure memorable with top-notch amenities and budget-friendly rates—book now!

With rooms from $86.99, Floating Sea Cove Resort & Marina provides friendly accommodations for travelers bound for Big Pine Key, creating an inviting and comfortable space for unwinding. Relax in accommodations that provide practical comfort, making your stay both convenient and economical.

Find your escape at Floating Sea Cove Resort & Marina, offering the perfect blend of calm and proximity to the attractions of Big Pine Key. Stay relaxed and enjoy added comfort on your Big Pine Key trip—book your room today!

Those visiting Big Pine Key will explore an elegant escape at Oceans Edge Key West Resort Hotel & Marina, where quality accommodations guarantee a seamless experience, with nightly rates from $179.99. Find a sumptuous retreat in rooms that blend opulent decor with high-tech amenities, designed for a luxurious stay.

Take time to relax at Oceans Edge Key West Resort Hotel & Marina, where a calm setting is complemented by the convenience of being near Big Pine Key. Unwind in Big Pine Key at a hotel where every detail is thoughtfully curated—lock in today!

Step into comfort redefined at The Perry Hotel & Marina Key West as you explore Big Pine Key, where refined accommodations promise a serene escape, with rates beginning at $156.99. Experience a new standard in luxury, with rooms that are thoughtfully designed to provide an exceptional level of comfort.

Discover a quiet escape at The Perry Hotel & Marina Key West, where the bustle of Big Pine Key is close enough to explore at your leisure. Enjoy every part of your Big Pine Key visit with a hotel that knows how to make you feel at home—lock in today!

At Aqua Lodges at Hurricane Hole Marina, travelers visiting Big Pine Key can enjoy snug, affordable rooms starting at $116.99, creating a comfortable, inviting environment ideal for relaxation. Stay in a room that provides a comfortable foundation for your travel plans, with necessary amenities and economical rates.

Take advantage of spacious rooms and a tranquil atmosphere at Aqua Lodges at Hurricane Hole Marina, while still being close enough to enjoy Big Pine Key. Stay smart and enjoy comfort on your Big Pine Key visit without overspending—secure now!

Relax in the elevated ambiance of Hyatt Vacation Club at Beach House Key West near Big Pine Key, where inviting rooms offer warmth and comfort, with rates starting from an accessible $267.99. Relax in accommodations that cater to discerning guests, providing luxurious amenities and attentive service.

Enjoy a restful stay at Hyatt Vacation Club at Beach House Key West, where calm lodgings provide a peaceful atmosphere close to Big Pine Key's offerings. Step into a Big Pine Key adventure where every moment is luxurious and enjoyable—book today!

Encounter a welcoming retreat at Beachside Resort & Residences on your visit to Big Pine Key, where refined accommodations provide relaxation, with nightly rates starting from $167.99. Relax in an environment where comfort meets luxury, featuring premium bedding and a serene atmosphere.

Find your peaceful getaway at Beachside Resort & Residences, a restful haven where guests can unwind and still visit Big Pine Key's lively offerings. Discover Big Pine Key with accommodations that provide unmatched comfort and convenience—secure now!

With a welcoming ambiance, Hilton Garden Inn Key West / The Keys Collection near Big Pine Key offers a refined experience for travelers, with inviting rooms available from a budget-friendly $146.99. Wake up to premium coffee options at Hilton Garden Inn, from freshly brewed morning picks to specialty espresso drinks.

Enjoy the serene atmosphere of Hilton Garden Inn Key West / The Keys Collection, providing the ideal base for travelers wanting to experience Big Pine Key at their own pace. Stay in Big Pine Key with a hotel that combines world-class service and unbeatable rates—book today!