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Top 24 Hotels In Charleston, Missouri 63834

Super 8 by Wyndham Charleston / Sikeston East MO

310 South Story St Charleston, MO

Guests bound for Charleston can enjoy affordable comfort at Super 8 by Wyndham Charleston / Sikeston East MO, with rooms beginning at $57.99, creating a tranquil and inviting atmosphere perfect for relaxation. Explore the area with Super 8's prime locations, offering easy access to local landmarks, parks, and shopping centers.

With downtown Charleston just a short trip away, guests at Super 8 by Wyndham Charleston / Sikeston East MO can easily explore the city’s best spots while staying in a quieter, more peaceful area. Plan your Charleston visit with budget-savvy, welcoming accommodations—book now!

  Call (855) 234-7135 to book with an agent.
  0.6 miles from Charleston, MO 63834

Starting at

$57.99

per night

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Quality Inn Charleston Sikeston

102 Drake St Charleston, MO

Guests traveling to Charleston will appreciate the inviting accommodations at Quality Inn Charleston Sikeston, with budget-friendly rooms starting at $66.99, creating a clean, comfortable atmosphere. Stay connected with Quality Inn's global news network access, keeping you informed with international and local news during your stay.

Guests at Quality Inn Charleston Sikeston will appreciate the proximity to downtown Charleston, making it easy to visit the city’s most exciting spots without the hassle of staying in the center. Plan your Charleston adventure with a hotel that’s as inviting as it is affordable—secure now!

  Call (855) 239-5277 to book with an agent.
  1.1 miles from Charleston, MO 63834

Starting at

$66.99

per night

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Eagle Inn Charleston

2811 East Marshall Street Charleston, MO

With rates from $69.29, Eagle Inn Charleston is a convenient choice for travelers to Charleston, creating a warm and comfortable space ideal for relaxation. Enjoy reliable comfort in rooms that provide everything you need for a worry-free visit at an economical price.

Eagle Inn Charleston offers a perfect blend of proximity and peace, giving guests easy access to downtown Charleston without being in the busiest parts of the city. Stay affordably and enjoy extra perks on your Charleston trip—reserve your room today!

  Call (855) 234-2997 to book with an agent.
  1.5 miles from Charleston, MO 63834

Starting at

$69.29

per night

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Country Yard Inn&Suite

110 South Interstate Drive Sikeston, MO

With rooms beginning at $54.99, Country Yard Inn&Suite offers inviting accommodations for travelers visiting Charleston, creating a comfortable and welcoming space for all guests. Find value in rooms that offer dependable comfort, ensuring a pleasant stay at a great price.

For a peaceful retreat, Country Yard Inn&Suite offers a quiet environment, with the added bonus of downtown Charleston being within a short drive. Plan your Charleston trip wisely with budget-friendly, cozy accommodations—book now!

  Call (855) 235-0725 to book with an agent.
  11.0 miles from Charleston, MO 63834

Starting at

$54.99

per night

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Days Inn&Suites by Wyndham Sikeston

220 South Interstate Dr Sikeston, MO

At Days Inn&Suites by Wyndham Sikeston, travelers visiting Charleston will find budget-conscious accommodations with rooms beginning at $64.99, creating a warm and inviting space. Appreciate the value of Days Inn's amenities, including in-room coffee makers and comfortable bedding, enhancing your stay.

At Days Inn&Suites by Wyndham Sikeston, the peaceful surroundings provide a restful stay, while downtown Charleston is just a convenient drive away. Stay smart and keep your Charleston trip within budget with a comfortable hotel—reserve now!

  Call (855) 235-0725 to book with an agent.
  11.0 miles from Charleston, MO 63834

Starting at

$64.99

per night

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Best Western Plus Sikeston

120 South Interstate Drive Sikeston, MO

Guests bound for Charleston can unwind at Best Western Plus Sikeston, where inviting rooms start at $76.99, creating a warm and welcoming space perfect for relaxation. Stay fit with the yoga mats provided in each room at Best Western Plus, encouraging a healthy lifestyle even while traveling.

For travelers seeking peace and proximity, Best Western Plus Sikeston provides the perfect blend of tranquility with downtown Charleston still nearby. Choose a hotel in Charleston that keeps both your comfort and wallet in mind—reserve now!

  Call (855) 233-0132 to book with an agent.
  11.0 miles from Charleston, MO 63834

Starting at

$76.99

per night

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Travel Inn & Suites Sikeston / Miner (i-55 Exit 67)

100 Matthews Lane Sikeston, MO

Guests bound for Charleston will find easygoing comfort at Travel Inn & Suites Sikeston / Miner (i-55 Exit 67), with inviting rooms starting at $62.99, creating a warm and welcoming space perfect for relaxation. Find efficiency and comfort in rooms that are designed with the budget traveler in mind, offering basic amenities and a clean setting.

For a calm stay, Travel Inn & Suites Sikeston / Miner (i-55 Exit 67) offers a peaceful retreat, with the added bonus of downtown Charleston being a smooth drive away. Make Charleston travel effortless and affordable with inviting accommodations—secure today!

  Call (855) 233-0132 to book with an agent.
  11.3 miles from Charleston, MO 63834

Starting at

$62.99

per night

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Comfort Inn & Suites Sikeston I-55

109 Matthews Ln Sikeston, MO

For a restful stay near Charleston, Comfort Inn & Suites Sikeston I-55 offers delightful accommodations with rooms from $87.99, creating a clean and comfortable environment perfect for relaxation. Appreciate the bright and clean atmosphere of Comfort Inn's properties, where guest comfort and satisfaction are the focus.

At Comfort Inn & Suites Sikeston I-55, visitors can find relaxation in peaceful surroundings, with downtown Charleston still accessible for a day of sightseeing. Make your Charleston travels stress-free and comfortable with well-rounded accommodations—book today!

  Call (855) 234-7135 to book with an agent.
  11.3 miles from Charleston, MO 63834

Starting at

$87.99

per night

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Quality Inn Cairo I-57

13201 Kessler Road Cairo, IL

With rates beginning at $80.99, Quality Inn Cairo I-57 is a smart choice for travelers to Charleston, creating a calm space perfect for rest and relaxation. Relax with confidence, knowing that Quality Inn prioritizes your safety and well-being with comprehensive cleaning protocols.

At Quality Inn Cairo I-57, guests can unwind in calm surroundings, while downtown Charleston is still nearby for a day of sightseeing. Enjoy your Charleston adventure with accommodations designed for relaxation—book now!

  Call (855) 235-0725 to book with an agent.
  11.4 miles from Charleston, MO 63834

Starting at

$80.99

per night

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Super 8 by Wyndham Sikeston / Miner Area

2609 East Malone Ave Sikeston, MO

With rates beginning at $60.00, Super 8 by Wyndham Sikeston / Miner Area is a convenient choice for travelers to Charleston, offering budget-friendly accommodations in a welcoming setting. Relax knowing Super 8 focuses on the essentials, providing straightforward amenities that matter most to travelers.

Travelers seeking quiet surroundings will appreciate Super 8 by Wyndham Sikeston / Miner Area, offering a calm atmosphere with downtown Charleston still nearby. Enjoy a practical, budget-conscious stay with perks in Charleston—book now!

  Call (855) 234-2997 to book with an agent.
  11.5 miles from Charleston, MO 63834

Starting at

$60.00

per night

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Hampton Inn Sikeston

1240 Commerce Drive Sikeston, MO

For a restful stay, Hampton Inn Sikeston offers tucked away accommodations with rates from $112.99, creating a welcoming space ideal for travelers visiting Charleston. Kickstart your day with Hampton's complimentary hot breakfast, a hearty and healthy way to start your morning.

Unwind at Hampton Inn Sikeston in a quiet setting, where downtown Charleston is still within easy reach for a day of adventure. Savor your Charleston experience with accommodations designed for relaxation—book today!

  Call (855) 233-0132 to book with an agent.
  14.2 miles from Charleston, MO 63834

Starting at

$112.99

per night

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Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel

115 Hospitality Dr Sikeston, MO

With affordable rooms from $129.00, Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel provides inviting comfort for guests bound for Charleston, creating a peaceful, welcoming environment ideal for relaxation. Enjoy the privacy of separate sleeping and living areas in the suites at Holiday Inn Express, ideal for business and leisure travelers.

A short, scenic drive takes guests from Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel into downtown Charleston, where they can explore and return to the calm of their stay. Revel in added perks and comfort for your Charleston stay without breaking the bank—lock in today!

  Call (855) 239-5277 to book with an agent.
  14.2 miles from Charleston, MO 63834

Starting at

$129.00

per night

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La Center Motel

474 West Kentucky Dr La Center, KY

For an affordable and restful stay, La Center Motel offers budget-friendly rooms with rates starting at $65.99, creating a clean and comfortable space near Charleston. Stay in a room that offers practical comfort and essential amenities, ensuring a pleasant and affordable visit.

Relax in the calm environment of La Center Motel, knowing that the many attractions of Charleston are never far away. Plan your Charleston getaway smartly with budget-savvy lodging—reserve your room today!

  Call (855) 239-5277 to book with an agent.
  22.3 miles from Charleston, MO 63834

Starting at

$65.99

per night

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Regency Inn

128 CHEEKWOOD LN Ullin, IL

At Regency Inn, guests bound for Charleston will find affordable accommodations with rates starting at $94.99, creating a clean and welcoming environment perfect for rest. Relax in accommodations that provide a welcoming environment, with everything you need for a comfortable and affordable visit.

Enjoy the peaceful environment at Regency Inn, perfect for those seeking relaxation while having quick access to Charleston. Enjoy more of Charleston with comfortable, cost-saving accommodations—book now!

  Call (855) 236-8982 to book with an agent.
  26.2 miles from Charleston, MO 63834

Starting at

$94.99

per night

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Courtyard by Marriott Cape Girardeau Downtown

400 Broadway St. Cape Girardeau, MO

Find comfort at Courtyard by Marriott Cape Girardeau Downtown when traveling to Charleston, where warm rooms create a peaceful environment, with affordable rates beginning at $149.99 per night. Embrace Courtyard's green initiatives, which include water-saving fixtures and recycling programs, reflecting a dedication to environmental sustainability.

Guests at Courtyard by Marriott Cape Girardeau Downtown can enjoy the serene surroundings while knowing the best of Charleston is just a drive away. Unwind after exploring Charleston with a hotel that’s dedicated to your comfort—lock in today!

  Call (855) 236-8982 to book with an agent.
  28.7 miles from Charleston, MO 63834

Starting at

$149.99

per night

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Candlewood Suites Cape Girardeau an IHG Hotel

485 South Mount Auburn Rd Cape Girardeau, MO

At Candlewood Suites Cape Girardeau an IHG Hotel, travelers to Charleston will find budget-friendly rooms with rates starting at $101.92, creating a clean, welcoming environment perfect for rest. Candlewood Suites offers a Weekly Housekeeping service, balancing thorough cleaning with your need for privacy.

At Candlewood Suites Cape Girardeau an IHG Hotel, guests are treated to restful accommodations with the advantage of being close to Charleston's top destinations. Make your Charleston travels both enjoyable and budget-friendly with inviting lodging—book today!

  Call (855) 233-7850 to book with an agent.
  28.8 miles from Charleston, MO 63834

Starting at

$101.92

per night

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Fairfield Inn & Suites by Marriott Cape Girardeau

433 CAPE WEST CROSSINGS Cape Girardeau, MO

At Fairfield Inn & Suites by Marriott Cape Girardeau, guests visiting Charleston can enjoy inviting accommodations with rates beginning at $124.99, creating a alluring and welcoming space. Appreciate the quiet hours at Fairfield, ensuring that every guest can enjoy undisturbed rest no matter the time of day.

Whether you're here for business or pleasure, Fairfield Inn & Suites by Marriott Cape Girardeau provides a peaceful setting that keeps Charleston within easy reach. Make the most of your Charleston visit with a hotel that delivers exceptional value—reserve now!

  Call (855) 234-2997 to book with an agent.
  28.9 miles from Charleston, MO 63834

Starting at

$124.99

per night

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The Riverview

777 Main St Cape Girardeau, MO

Find warmth and comfort at The Riverview as you travel to Charleston, where safe accommodations offer quality, with nightly rates beginning at just $107.99. Find a delightful mix of comfort and luxury in rooms that offer advanced amenities and refined design.

Stay at The Riverview to enjoy the best of both worlds—quiet, restful accommodations with Charleston never far from reach. Discover how enjoyable Charleston can be with a hotel that offers luxury at every turn—secure now!

  Call (855) 234-7135 to book with an agent.
  29.1 miles from Charleston, MO 63834

Starting at

$107.99

per night

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Hampton Inn Cape Girardeau I 55 East

207 South Mt. Auburn Rd Cape Girardeau, MO

At Hampton Inn Cape Girardeau I 55 East, guests bound for Charleston will find intimate-feeling accommodations with rates beginning at $113.99, creating a warm and welcoming environment. Enjoy a seamless travel experience with Hampton's efficient online check-in process, saving you time upon arrival.

Offering a perfect retreat from the hustle and bustle, Hampton Inn Cape Girardeau I 55 East is an ideal base for exploring Charleston. Discover how easy Charleston travel can be with a hotel that adds value to your stay—reserve today!

  Call (855) 239-4019 to book with an agent.
  29.2 miles from Charleston, MO 63834

Starting at

$113.99

per night

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Rockwood Inn

603 Henderson Ave Cape Girardeau, MO

At Rockwood Inn, travelers bound for Charleston will find heartwarming, affordable rooms starting at $151.99, creating a clean, comfortable space perfect for relaxation. Stay in rooms that cater to practical travel needs, offering basic comforts and a straightforward experience.

At Rockwood Inn, you’ll be able to relax in a peaceful environment while keeping the sights of Charleston easily accessible. Choose value-driven comfort for your Charleston travels and enjoy more—lock in now!

  Call (855) 233-7850 to book with an agent.
  29.4 miles from Charleston, MO 63834

Starting at

$151.99

per night

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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel

3253 William Street Cape Girardeau, MO

With budget-conscious rooms starting at $124.00, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel is a practical option for travelers to Charleston, providing a welcoming space ideal for relaxation. Refresh and recharge in Holiday Inn Express's stylish and functional bathrooms, equipped with powerful showers and quality toiletries.

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel, you’ll find a restful atmosphere that keeps the excitement of Charleston within easy reach. Stay relaxed and on budget while exploring Charleston with thoughtfully designed lodging—lock in today!

  Call (855) 239-4019 to book with an agent.
  29.6 miles from Charleston, MO 63834

Starting at

$124.00

per night

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Town House Inn Cape Giradreau

505 North Kingshighway Street Cape Girardeau, MO

Guests bound for Charleston can enjoy budget-friendly comfort at Town House Inn Cape Giradreau, where friendly rooms start at $55.00, creating a welcoming space perfect for relaxation. Stay in accommodations that deliver extra comfort and amenities, ensuring a satisfying and budget-friendly experience.

Escape to Town House Inn Cape Giradreau for a quiet retreat, where guests can relax in comfort while keeping Charleston's attractions nearby. Make your Charleston adventure exceptional without breaking the bank—secure your room today!

  Call (855) 239-4019 to book with an agent.
  29.9 miles from Charleston, MO 63834

Starting at

$55.00

per night

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Travel Inn

301 Route Ad Marston, MO

At Travel Inn, travelers bound for Charleston will find budget-friendly rooms with rates starting at $60.96, creating a sheltered and welcoming environment perfect for relaxation. Enjoy a stay that offers more comfort and amenities, providing a pleasant and affordable travel experience.

At Travel Inn, you can enjoy the balance of a quiet stay while keeping Charleston just a short drive away. Get the most out of Charleston with lodging that makes your visit effortless—reserve now!

  Call (855) 234-7135 to book with an agent.
  31.5 miles from Charleston, MO 63834

Starting at

$60.96

per night

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Quality Inn

2011 North Kingshighway Cape Girardeau, MO

Guests bound for Charleston will find inviting comfort at Quality Inn, where budget-friendly rooms start at $61.00, creating a clean and welcoming environment. Take advantage of Quality Inn's technology hubs, offering guests access to the latest gadgets and tech support.

Guests seeking a peaceful stay will love Quality Inn, where calm surroundings are complemented by proximity to Charleston. Make your Charleston adventure both relaxing and affordable with top-notch amenities—book today!

  Call (855) 233-7850 to book with an agent.
  31.9 miles from Charleston, MO 63834

Starting at

$61.00

per night

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