The best deals on hotels when visiting Clayton in South Carolina.

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Top 24 Hotels In Clayton, South Carolina 29015

Home2 Suites by Hilton Newberry

111 Landworks Avenue Newberry, SC

Stay comfortably at Home2 Suites by Hilton Newberry on your journey to Clayton, where intimate-feeling accommodations provide a relaxing stay, with room rates beginning at an affordable $268.00. Appreciate the community atmosphere at Home2 Suites, fostering connections through shared spaces and guest events.

Travelers seeking quiet surroundings will appreciate Home2 Suites by Hilton Newberry, offering a calm atmosphere with downtown Clayton still nearby. Stay in Clayton with a hotel that brings relaxation and affordability together—secure now!

  Call (855) 234-2997 to book with an agent.
  15.4 miles from Clayton, SC 29015

Starting at

$268.00

per night

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Americas Best Value Inn Winnsboro SC

1894 US Highway 321 Bypass South Winnsboro, SC

With rates beginning at $68.99, Americas Best Value Inn Winnsboro SC offers budget-conscious accommodations for those bound for Clayton, creating a soothing, comfortable environment. Relax in Americas Best Value Inn's outdoor areas, where you can enjoy fresh air and socialize in a pleasant setting.

Positioned just outside of Clayton, Americas Best Value Inn Winnsboro SC provides the perfect base for exploring the area while enjoying a peaceful retreat. Book a practical, inviting hotel for your Clayton adventure and save—secure now!

  Call (855) 235-0725 to book with an agent.
  21.2 miles from Clayton, SC 29015

Starting at

$68.99

per night

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Executive Inn Ridgeway I-77

70 Contractors Way Ridgeway, SC

With rates from $70.00, Executive Inn Ridgeway I-77 provides secure comfort for guests traveling to Clayton, creating a warm and welcoming environment ideal for rest. Stay in accommodations that offer a bit more luxury and convenience, making your visit enjoyable and budget-friendly.

Unwind at Executive Inn Ridgeway I-77, a peaceful retreat offering both relaxation and the convenience of Clayton just a short drive away. Unwind in Clayton with budget-friendly accommodations that don’t skimp on comfort—book now!

  Call (855) 234-2997 to book with an agent.
  26.7 miles from Clayton, SC 29015

Starting at

$70.00

per night

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Motel 6 Richburg SC

2912 Pkwy. Blvd Chester, SC

With rooms beginning at $68.99, Motel 6 Richburg SC provides budget-friendly accommodations for guests headed to Clayton, creating a enveloping and inviting space for rest. Take advantage of the efficient space-saving designs in Motel 6 rooms, where everything you need is cleverly arranged for ease and comfort.

Discover your ideal getaway at Motel 6 Richburg SC, where peaceful accommodations are paired with proximity to Clayton's top sights. Enjoy reliable, comfortable lodging that fits your budget in Clayton—secure now!

  Call (855) 236-8982 to book with an agent.
  28.0 miles from Clayton, SC 29015

Starting at

$68.99

per night

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Quality Inn & Suites

3041 Lancaster Hwy Richburg, SC

Guests traveling to Clayton will find inviting accommodations at Quality Inn & Suites, where pleasant rooms start at $96.99, creating a warm and welcoming space. Enjoy a seamless stay with Quality Inn's express services, including fast check-in and check-out to accommodate your schedule.

Escape to Quality Inn & Suites for a refreshing stay, where peaceful surroundings are paired with the convenience of Clayton's top spots. Enjoy an effortless Clayton adventure with budget-conscious, inviting lodging—book now!

  Call (855) 239-5277 to book with an agent.
  28.0 miles from Clayton, SC 29015

Starting at

$96.99

per night

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Baymont by Wyndham Richburg / Chester Area

3085 Lancaster Hwy Richburg, SC

For an affordable, restful visit, Baymont by Wyndham Richburg / Chester Area offers inviting rooms with rates starting at $93.00, creating a warm and welcoming atmosphere perfect for guests bound for Clayton. Relax in Baymont by Wyndham’s welcoming common areas, designed with comfort and convenience in mind.

At Baymont by Wyndham Richburg / Chester Area, you’ll find the ideal combination of calm surroundings and proximity to all that Clayton has to offer. Choose value and comfort for your Clayton travels—book your affordable stay now!

  Call (855) 235-6136 to book with an agent.
  28.0 miles from Clayton, SC 29015

Starting at

$93.00

per night

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Holiday Inn Express Richburg an IHG Hotel

3190 COMMERCE DRIVE Richburg, SC

With budget-friendly rooms beginning at $134.00, Holiday Inn Express Richburg an IHG Hotel is an ideal choice for guests traveling to Clayton, creating a warm, inviting space. Explore the local area with confidence, thanks to the insightful recommendations provided by Holiday Inn Express's knowledgeable staff.

At Holiday Inn Express Richburg an IHG Hotel, you’ll find restful accommodations and the convenience of being close to Clayton's most exciting destinations. Make your Clayton trip memorable with a hotel that offers more for less—secure your stay now!

  Call (855) 235-0725 to book with an agent.
  28.2 miles from Clayton, SC 29015

Starting at

$134.00

per night

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Days Inn by Wyndham Richburg

3217 Lancaster Hwy Richburg, SC

With affordable rooms beginning at $70.99, Days Inn by Wyndham Richburg provides budget-conscious accommodations for travelers headed to Clayton, creating a warm, welcoming environment. Explore the advantages of staying at Days Inn, where you can expect more than just a room but a fulfilling travel experience.

Situated outside the hustle of the city, Days Inn by Wyndham Richburg offers a quiet spot to relax while keeping Clayton's highlights nearby. Stay cozy and within budget on your Clayton adventure—lock in your room today!

  Call (855) 234-7135 to book with an agent.
  28.3 miles from Clayton, SC 29015

Starting at

$70.99

per night

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Hyatt Place Columbia / Harbison

1130 Kinley Road Irmo, SC

Relax at Hyatt Place Columbia / Harbison on your visit to Clayton, where restful accommodations provide quality and warmth, with affordable nightly rates starting at $399.00. Relax in Hyatt Place's family-friendly accommodations, which include essential amenities for travelers with children.

Whether for work or leisure, Hyatt Place Columbia / Harbison offers a balance of tranquility and easy access to Clayton's major attractions. Discover how great Clayton can be with accommodations that go above and beyond—lock in today!

  Call (855) 234-2997 to book with an agent.
  31.0 miles from Clayton, SC 29015

Starting at

$399.00

per night

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Extended Stay America Select Suites Columbia Northwest / Harbison

1170 Kinley Road Irmo, SC

Guests visiting Clayton can unwind at Extended Stay America Select Suites Columbia Northwest / Harbison, where comfortable accommodations start at $244.99, creating a welcoming and comfortable environment for rest. Experience the convenience of dining discounts provided by Extended Stay America, offering savings at nearby restaurants.

Find your ideal balance at Extended Stay America Select Suites Columbia Northwest / Harbison, where guests can experience the tranquility of the surroundings while Clayton stays close by. Stay worry-free in Clayton with a hotel that offers all the essentials at a great price—lock in now!

  Call (855) 234-2997 to book with an agent.
  31.1 miles from Clayton, SC 29015

Starting at

$244.99

per night

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Comfort Inn Blythewood North Columbia

436 McNulty St Blythewood, SC

Find a warm retreat at Comfort Inn Blythewood North Columbia as you travel to Clayton, with cozy-like accommodations crafted for comfort, with room rates starting at $151.99. Relax knowing Comfort Inn offers pet-friendly accommodations at select locations, welcoming your furry friends to join your travels.

At Comfort Inn Blythewood North Columbia, you’ll experience restful accommodations and the advantage of being close to Clayton for day trips and adventures. Enjoy every moment of your Clayton trip with accommodations that go the extra mile—lock in today!

  Call (855) 239-5277 to book with an agent.
  31.3 miles from Clayton, SC 29015

Starting at

$151.99

per night

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Home2 Suites by Hilton Blythewood SC

92 Creech Rd Blythewood, SC

Relax in the comfortable surroundings of Home2 Suites by Hilton Blythewood SC as you visit Clayton, where inviting rooms offer quality at an affordable starting rate of $222.99 per night. Relax in the comfort of a hotel that feels like a second home, with thoughtful amenities and a focus on creating a homey atmosphere.

Escape the urban buzz at Home2 Suites by Hilton Blythewood SC, offering peaceful lodgings just a short drive from the dynamic heart of Clayton. Enjoy the benefits of a Clayton hotel that combines elegance with savings—reserve now!

  Call (855) 235-6136 to book with an agent.
  31.3 miles from Clayton, SC 29015

Starting at

$222.99

per night

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Days Inn by Wyndham Blythewood North Columbia

114 Blythewood Rd Blythewood, SC

For an affordable stay, Days Inn by Wyndham Blythewood North Columbia offers calm accommodations with rates beginning at $145.99, creating a clean, comfortable environment near Clayton. Enjoy essential in-room amenities such as coffee makers and cozy bedding, designed to make your stay as homely as possible.

Enjoy a peaceful stay at Days Inn by Wyndham Blythewood North Columbia, where guests can relax and still visit Clayton's lively streets whenever they choose. Stay affordably and comfortably on your Clayton getaway—reserve your room today!

  Call (855) 239-5277 to book with an agent.
  31.4 miles from Clayton, SC 29015

Starting at

$145.99

per night

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Holiday Inn Express Hotel & Suites Blythewood an IHG Hotel

120 Creech Road Blythewood, SC

Experience the warmth and relaxation offered at Holiday Inn Express Hotel & Suites Blythewood an IHG Hotel near Clayton, where inviting rooms start from a budget-friendly $214.00 per night. Savor the convenience of Holiday Inn Express's grab-and-go breakfast options, perfect for early risers or guests on the move.

Discover the perfect escape at Holiday Inn Express Hotel & Suites Blythewood an IHG Hotel, where the peaceful ambiance is matched by the convenience of Clayton's nearby attractions. Experience a hotel in Clayton that ensures you’re well taken care of—book your room today!

  Call (855) 234-7135 to book with an agent.
  31.4 miles from Clayton, SC 29015

Starting at

$214.00

per night

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Tru by Hilton Harbison Columbia

271 Columbiana Drive Columbia, SC

For an inviting and budget-conscious stay near Clayton, Tru by Hilton Harbison Columbia offers plush rooms with rates beginning at $285.99, creating a welcoming atmosphere for rest. Stay fit on the go with Tru by Hilton’s fitness center, equipped with the latest cardio and strength equipment.

Found just beyond the busy city center, Tru by Hilton Harbison Columbia provides a calm setting while keeping Clayton's top spots within easy reach. Take advantage of thoughtful amenities and affordable rates for your Clayton trip—book today!

  Call (855) 234-5074 to book with an agent.
  31.5 miles from Clayton, SC 29015

Starting at

$285.99

per night

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Quality Inn & Suites Columbia Harbison

350 Columbiana Dr Columbia, SC

At Quality Inn & Suites Columbia Harbison, travelers headed to Clayton will find inviting accommodations with rooms starting at $357.99, creating a clean and comfortable space. Take advantage of Quality Inn's pet-friendly policy, allowing you to bring your furry friends along on your travels.

Quality Inn & Suites Columbia Harbison offers a quiet getaway, with easy access to Clayton's most exciting destinations only a short drive away. Experience a well-rounded stay perfect for your Clayton travels—reserve today!

  Call (855) 236-8982 to book with an agent.
  31.5 miles from Clayton, SC 29015

Starting at

$357.99

per night

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MainStay Suites Columbia Harbison

350 Columbiana Drive Columbia, SC

At MainStay Suites Columbia Harbison, travelers to Clayton will find tucked away, budget-friendly rooms with rates starting at $329.99, creating a warm and inviting space for relaxation. Relax on MainStay Suites’ outdoor patios and balconies, offering a pleasant space to enjoy fresh air and relaxation.

Travelers will love the serene setting at MainStay Suites Columbia Harbison, where peaceful accommodations offer a relaxing stay near Clayton. Enjoy your Clayton adventure with a hotel that pairs quality and affordability—lock in today!

  Call (855) 236-8982 to book with an agent.
  31.5 miles from Clayton, SC 29015

Starting at

$329.99

per night

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Fairfield Inn by Marriott Columbia Northwest

320 Columbiana Dr Columbia, SC

For a budget-friendly and calm stay, Fairfield Inn by Marriott Columbia Northwest offers inviting rooms with rates from $379.99, creating a warm and comfortable environment near Clayton. Appreciate the spaciousness of Fairfield suites, offering separate areas to sleep, work, and relax for a home-like experience.

At Fairfield Inn by Marriott Columbia Northwest, guests can relax in peaceful surroundings while having quick access to Clayton's lively downtown. Get ready for a Clayton trip that’s as affordable as it is memorable—lock in today!

  Call (855) 234-5074 to book with an agent.
  31.6 miles from Clayton, SC 29015

Starting at

$379.99

per night

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Comfort Suites Columbia at Harbison

750 Saturn Pkwy Columbia, SC

For budget-conscious travelers visiting Clayton, Comfort Suites Columbia at Harbison offers inviting accommodations with rates beginning at $373.99, creating a clean and comfortable space. Enjoy a personal touch with Comfort Suites' custom concierge services, catering to your unique needs and preferences.

Guests will appreciate the quiet environment at Comfort Suites Columbia at Harbison, where restful accommodations are never too far from Clayton's activities. Unwind after exploring Clayton with a hotel that keeps both comfort and savings in mind—secure now!

  Call (855) 234-2997 to book with an agent.
  32.3 miles from Clayton, SC 29015

Starting at

$373.99

per night

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Hampton Inn Columbia I-26 / Harbison Blvd.

101 Woodcross Dr Columbia, SC

For an affordable stay near Clayton, Hampton Inn Columbia I-26 / Harbison Blvd. Offers welcoming rooms with rates from $314.99, creating a welcoming, comfortable atmosphere perfect for rest. Relax in the vibrant atmosphere of Hampton’s pool areas, where comfortable lounging and refreshing swims await under the sun or stars.

Unwind in the serene setting of Hampton Inn Columbia I-26 / Harbison Blvd., while knowing Clayton's lively streets are never too far away. Enjoy stress-free Clayton travel with accommodations designed for relaxation and savings—book today!

  Call (855) 235-6136 to book with an agent.
  32.4 miles from Clayton, SC 29015

Starting at

$314.99

per night

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Super 8 by Wyndham Harbison / Parkridge Hospital

411 Piney Grove Rd Columbia, SC

With rooms starting at $179.99, Super 8 by Wyndham Harbison / Parkridge Hospital provides inviting accommodations for travelers to Clayton, creating a warm, welcoming environment ideal for relaxation. Find great value without compromise at Super 8, offering affordable rates while maintaining strict standards for quality and cleanliness.

At Super 8 by Wyndham Harbison / Parkridge Hospital, you'll find a peaceful retreat with the added benefit of being close to Clayton for exploration. Enjoy enhanced comfort at a great price for your Clayton travels—secure now!

  Call (855) 234-7135 to book with an agent.
  33.0 miles from Clayton, SC 29015

Starting at

$179.99

per night

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Suburban Studios Columbia Harbison

499 Piney Grove Rd. Building B Columbia, SC

With affordable rooms starting at $123.20, Suburban Studios Columbia Harbison provides budget-conscious comfort for guests visiting Clayton, creating a welcoming and relaxing space. Experience reliable comfort in rooms that offer standard amenities, ensuring a pleasant and budget-conscious stay.

Relax at Suburban Studios Columbia Harbison, where guests can unwind in a tranquil setting while still being close to the excitement of Clayton. Lock in a welcoming, cost-conscious stay for your Clayton visit—reserve today!

  Call (855) 234-5074 to book with an agent.
  33.0 miles from Clayton, SC 29015

Starting at

$123.20

per night

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Landsford Inn

5721 Lancaster Highway Fort Lawn, SC

At Landsford Inn, guests traveling to Clayton will find relaxed, budget-friendly rooms starting at $99.99, creating a clean and welcoming environment for relaxation. Relax in accommodations that offer a clean and welcoming environment, perfect for rest after a day of exploring or business.

Discover your ideal getaway at Landsford Inn, where peaceful accommodations are paired with proximity to Clayton's top sights. Get ready for a Clayton stay that’s as comfortable as it is affordable—reserve your room now!

  Call (855) 234-2997 to book with an agent.
  33.2 miles from Clayton, SC 29015

Starting at

$99.99

per night

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Hampton Inn & Suites Columbia Killian Road

1310 Roberts Branch Pkwy Columbia, SC

Guests visiting Clayton will appreciate the inviting comfort at Hampton Inn & Suites Columbia Killian Road, where intimate rooms begin at $238.99, creating a warm, welcoming atmosphere. Ride around town with Hampton’s bike rental service, a fun and eco-friendly way to explore local sights and sounds.

At Hampton Inn & Suites Columbia Killian Road, you can enjoy the balance of a quiet stay while keeping Clayton just a short drive away. Unwind in Clayton with accommodations that blend affordability and relaxation—book today!

  Call (855) 233-7850 to book with an agent.
  35.6 miles from Clayton, SC 29015

Starting at

$238.99

per night

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