Top 24 Hotels In Commerce, Missouri 63780

Relax in the comfy ambiance of Courtyard by Marriott Cape Girardeau Downtown as you journey to Commerce, where inviting rooms create a peaceful stay, with nightly rates starting at $149.99. Enjoy the efficiency of Courtyard's mobile room key, allowing you to access your room and other hotel areas with just your smartphone.

For travelers looking for peace, Courtyard by Marriott Cape Girardeau Downtown offers quiet surroundings while keeping downtown Commerce just a convenient drive away. Take your Commerce adventure to the next level with a hotel that offers more for less—lock in today!

With budget-friendly rooms beginning at $97.00, Candlewood Suites Cape Girardeau an IHG Hotel provides inviting comfort for travelers bound for Commerce, creating a warm and welcoming space. Reliable Wi-Fi at Candlewood Suites ensures you stay connected for all your online needs, from work to entertainment.

Relax at Candlewood Suites Cape Girardeau an IHG Hotel in peaceful surroundings, knowing that downtown Commerce is within easy reach for city exploration. Rest easy in Commerce with accommodations that deliver value and quality—secure your room today!

Uncover a refined escape at The Riverview as you explore Commerce, where soft rooms offer comfort and warmth, with inviting rates starting at just $117.99. Find your ideal luxury retreat in rooms that combine high-end amenities with impeccable service and style.

For travelers looking to balance relaxation with exploration, The Riverview offers tranquility while downtown Commerce is still close enough to visit. Get ready for a Commerce trip that’s equal parts elegance and affordability—lock in today!

Guests bound for Commerce can unwind at Fairfield Inn & Suites by Marriott Cape Girardeau, where inviting rooms start at $124.99, creating a warm and comfortable space ideal for relaxation. Stay energized with Fairfield’s power snack packs, available upon request to keep you fueled during your outings.

Travelers seeking peace and quiet will love Fairfield Inn & Suites by Marriott Cape Girardeau, offering a calm retreat with easy access to downtown Commerce. Make your Commerce experience stress-free with a hotel that offers unbeatable value—book today!

Guests bound for Commerce will appreciate the inviting accommodations at Rockwood Inn, where charming rooms start at $151.99, creating a warm, welcoming environment. Relax in accommodations that provide a comfortable environment, with everything you need for a worry-free visit.

Guests at Rockwood Inn will love the quiet atmosphere, with downtown Commerce remaining nearby for easy access to sightseeing. Enjoy Commerce from a hotel that balances comfort and cost savings—secure today!

With budget-friendly rooms beginning at $117.99, Hampton Inn Cape Girardeau I 55 East is a practical choice for travelers to Commerce, creating a welcoming and comfortable space. Celebrate your special events at select Hampton locations, offering versatile spaces for meetings, receptions, and gatherings.

Rest easy at Hampton Inn Cape Girardeau I 55 East, where guests can relax in serene surroundings with downtown Commerce within reach for sightseeing. Enjoy more of Commerce with a practical hotel designed for your convenience—reserve now!

For an inviting stay near Commerce, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel offers relaxing accommodations with rooms starting at $129.00, creating a clean and comfortable environment for rest. Discover the efficiency of Holiday Inn Express's self-service check-in kiosks, designed for quick arrivals and departures.

A relaxing stay awaits at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 an IHG Hotel, where serene surroundings provide a restful atmosphere and downtown Commerce remains accessible. Settle in and enjoy your Commerce stay with amenities that make all the difference—reserve now!

Guests traveling to Commerce will find friendly accommodations at Town House Inn Cape Giradreau, with rooms starting at $60.00, creating a warm and welcoming atmosphere. Find comfort and convenience in rooms that provide a cozy atmosphere with all the essential amenities for a pleasant stay.

At Town House Inn Cape Giradreau, guests can experience peaceful surroundings while having downtown Commerce within easy driving distance. Stay smart and relaxed in Commerce with a hotel that checks every box—book today!

At Quality Inn, guests bound for Commerce can enjoy inviting rooms with rates starting at $63.00, creating a clean and comfortable space ideal for relaxation. Indulge in a local culinary experience with Quality Inn's restaurant partnerships, offering guests a taste of regional specialties.

At Quality Inn, guests can unwind in peaceful surroundings, while downtown Commerce remains easily accessible for a day of sightseeing. Treat yourself to a seamless Commerce adventure with affordable, welcoming lodging—secure now!

For an affordable stay near Commerce, Quality Inn Cairo I-57 offers inviting rooms with rates starting at $80.99, creating a clean and welcoming space ideal for rest. Experience the vibrant social scene at Quality Inn's happy hour events, featuring local beverages and light snacks.

Guests at Quality Inn Cairo I-57 can unwind in a tranquil setting, with the added benefit of downtown Commerce being a convenient drive away. Explore Commerce effortlessly with a hotel that offers exceptional value—reserve now!

At La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau, travelers to Commerce will find calm, budget-friendly accommodations with rates from $76.99, creating a welcoming environment perfect for rest. Relax in the eco-friendly surroundings of La Quinta, where green practices are integrated into every aspect of the hotel’s operation.

Guests at La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau can unwind in a tranquil setting, while knowing that downtown Commerce is just a convenient drive away. Maximize your Commerce adventure with a hotel that offers unbeatable value—secure now!

With rates from $88.99, Comfort Suites Jackson Cape Girardeau provides inviting accommodations for guests bound for Commerce, creating a comfortable and comfortable atmosphere for relaxation. Take advantage of Comfort Suites' mobile app, providing a seamless way to manage your reservations and access hotel services.

For those seeking a blend of relaxation and city exploration, Comfort Suites Jackson Cape Girardeau offers tranquility with downtown Commerce a drive away. Enjoy Commerce without compromise with a hotel that delivers exceptional value—reserve now!

Guests traveling to Commerce will enjoy the affordable comfort at Regency Inn, where rooms start at $94.99, creating a warm, inviting atmosphere for relaxation. Find comfort and convenience in rooms that deliver essential amenities, perfect for travelers looking for reliability and value.

Travelers can relax in the calm environment of Regency Inn, while knowing downtown Commerce remains within easy driving distance. Stay affordably and comfortably while visiting Commerce—reserve your room today!

At Super 8 by Wyndham Charleston / Sikeston East MO, guests bound for Commerce can enjoy inviting accommodations with rooms starting at $58.99, providing a warm and comfortable environment for relaxation. Rely on Super 8 for a consistent and dependable lodging experience, no matter where your travels take you.

At Super 8 by Wyndham Charleston / Sikeston East MO, guests can relax in peaceful surroundings, with downtown Commerce just a comfortable drive away for city exploration. Book now and enjoy a practical, affordable Commerce stay—reserve your room today!

With rates beginning at $69.29, Eagle Inn Charleston provides affordable comfort for guests bound for Commerce, creating a welcoming, friendly environment perfect for rest. Find value in rooms that offer the essentials for a comfortable visit, making your stay both enjoyable and economical.

Enjoy a relaxing stay at Eagle Inn Charleston, where calm surroundings offer a peaceful retreat and downtown Commerce is just a short drive away. Stay affordably and experience the best of Commerce with ease—reserve your room today!

With rooms starting at $67.99, Quality Inn Charleston Sikeston offers inviting accommodations for travelers to Commerce, providing a welcoming space ideal for a relaxing stay. Stay active with Quality Inn's recreational facilities, including tennis courts and basketball courts at select locations.

Travelers seeking both peace and proximity will find Quality Inn Charleston Sikeston ideal, with downtown Commerce still within reach for exploration. Choose a Commerce hotel that keeps you comfortable and your budget intact—reserve now!

For a comfortable stay near Commerce, Country Yard Inn&Suite offers budget-conscious accommodations with rates from $51.99, creating a warm and inviting atmosphere. Experience a comfortable stay with rooms that offer the basics for a worry-free visit at a great price.

Guests at Country Yard Inn&Suite can unwind in a tranquil setting, with the attractions of downtown Commerce still within easy reach by car. Plan a practical, budget-friendly stay for your Commerce travels—book today!

For those traveling to Commerce, Best Western Plus Sikeston offers affordable rooms with rates starting at $88.99, creating a clean, comfortable atmosphere ideal for rest. Take advantage of the 24-hour business centers at Best Western Plus, fully equipped for your connectivity and productivity needs.

At Best Western Plus Sikeston, guests can enjoy the quiet surroundings, with downtown Commerce just a short drive away for city adventures. Discover the best way to enjoy Commerce with cost-effective, practical accommodations—secure now!

For an affordable and comfortable stay, Travel Inn & Suites Sikeston / Miner (i-55 Exit 67) offers inviting rooms with rates starting at $62.99, creating a clean, welcoming environment near Commerce. Enjoy a functional stay, where rooms provide the essentials for comfort and convenience, without any unnecessary extras.

Unwind in the peaceful environment at Travel Inn & Suites Sikeston / Miner (i-55 Exit 67), where the calm atmosphere is complemented by easy access to downtown Commerce. Choose a hotel in Commerce that keeps both your comfort and wallet in mind—reserve now!

Guests visiting Commerce will appreciate the serene comfort at Days Inn&Suites by Wyndham Sikeston, where budget-friendly rooms start at $64.99, creating a warm and inviting space. Discover the convenience of Days Inn's 24-hour business centers, providing the tools you need to stay productive.

For a restful stay, Days Inn&Suites by Wyndham Sikeston offers serene surroundings with downtown Commerce still close enough for easy access. Book a reliable, affordable hotel for your Commerce trip and enjoy added savings!

With rates beginning at $54.99, Town House Inn is a smart choice for travelers to Commerce, creating a delightful space perfect for rest and relaxation. Find an enhanced stay experience in accommodations that offer extra amenities and comfort at a great value.

For a quiet stay, Town House Inn offers serene surroundings with the convenience of downtown Commerce still a short drive away. Discover the joy of Commerce with a hotel that pairs convenience with affordability—lock in today!

Guests bound for Commerce can enjoy pleasant comfort at Comfort Inn & Suites Sikeston I-55, where rooms start at $106.99, creating a welcoming environment ideal for relaxation. Benefit from Comfort Inn's 100 percent Satisfaction Guarantee, reflecting the brand's commitment to guest satisfaction.

At Comfort Inn & Suites Sikeston I-55, visitors can unwind in a more serene environment, knowing that downtown Commerce is still within reach for a day of sightseeing. Discover how great Commerce can be with accommodations that keep you comfortable—secure now!

For a intimate, affordable stay, Super 8 by Wyndham Sikeston / Miner Area offers budget-friendly comfort with rooms from $59.99, creating a clean and welcoming space perfect for guests. Enjoy the simplicity and efficiency of Super 8's check-in and check-out process, designed to get you on your way quickly.

For a restful stay, Super 8 by Wyndham Sikeston / Miner Area offers quiet surroundings with the convenience of downtown Commerce still being within easy reach. Stay affordably and comfortably on your Commerce getaway—lock in your hotel room today!

At Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel, travelers visiting Commerce will find inviting accommodations with rooms from $159.00, creating a warm and welcoming space ideal for rest. Experience the convenience of Holiday Inn Express's mobile app, offering digital room keys and streamlined service requests.

Find your calm retreat at Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel, a peaceful stay with the advantage of being close to Commerce whenever you're ready to explore. Elevate your Commerce travels with budget-conscious, well-equipped lodging—lock in today!