The best deals on hotels when visiting De Soto in Wisconsin.

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Top 24 Hotels In De Soto, Wisconsin 54624

Scenic Valley Motel

1608 Main St Lansing, IA

With budget-conscious rooms starting at $76.99, Scenic Valley Motel provides affordable comfort for guests visiting De Soto, creating a clean and harmonious environment for rest. Stay in rooms that emphasize both comfort and value, offering a straightforward experience that meets your travel needs.

Take a break from the busy city life at Scenic Valley Motel, a quiet escape that's still connected to the heart of De Soto. Make your De Soto experience both enjoyable and economical—lock in your stay today!

  Call (855) 235-0725 to book with an agent.
  5.1 miles from DE Soto, WI 54624

Starting at

$76.99

per night

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Sportsmen Motel

2753 Iowa 76 Dorchester, IA

Guests bound for De Soto will appreciate the budget-friendly comfort at Sportsmen Motel, with rooms starting at $71.99, creating a warm and welcoming atmosphere. Enjoy the convenience of rooms equipped with necessary comforts, providing a solid foundation for a budget-friendly journey.

Guests staying at Sportsmen Motel will enjoy the calm environment, while knowing downtown De Soto is a short drive away. Enjoy De Soto to the fullest with budget-wise, inviting hotel rooms—book now!

  Call (855) 234-5074 to book with an agent.
  14.8 miles from DE Soto, WI 54624

Starting at

$71.99

per night

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Boarders Inn & Suites by Cobblestone Hotels – Waukon

407 Rossville Rd Waukon, IA

Embrace relaxation at Boarders Inn & Suites by Cobblestone Hotels – Waukon on your trip to De Soto, where inviting rooms offer comfort, with budget-friendly rates beginning at $89.99. Experience the ultimate in comfort and luxury, with rooms that are meticulously designed to meet your every need.

For those looking to unwind, Boarders Inn & Suites by Cobblestone Hotels – Waukon provides a restful retreat while keeping downtown De Soto close enough for exploration. Experience a De Soto visit that’s both relaxing and inspiring with refined accommodations—lock in today!

  Call (855) 236-8982 to book with an agent.
  17.9 miles from DE Soto, WI 54624

Starting at

$89.99

per night

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AmericInn by Wyndham Viroqua

1325 North Main St Viroqua, WI

At AmericInn by Wyndham Viroqua, guests bound for De Soto will enjoy budget-friendly comfort with rooms starting at $88.99, creating a warm and welcoming atmosphere. Relax with a book or catch up on emails in AmericInn by Wyndham’s quiet and comfortable lobby areas.

With a relaxing drive into downtown De Soto, guests at AmericInn by Wyndham Viroqua can explore the city’s best spots while retreating to the peace and quiet of their stay. Plan your De Soto travels with a hotel that’s designed for comfort and savings—secure now!

  Call (855) 239-5277 to book with an agent.
  18.5 miles from DE Soto, WI 54624

Starting at

$88.99

per night

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Welch Motel

3643 Mormon Coulee Rd. La Crosse, WI

For an affordable and welcoming stay near De Soto, Welch Motel offers budget-friendly rooms with rates from $49.99, creating a clean and comfortable atmosphere. Enjoy a functional stay, where rooms provide the essentials for comfort and convenience, without any unnecessary extras.

Find your retreat at Welch Motel, where calm surroundings are paired with easy connections to the vibrant offerings of De Soto. Treat yourself to a De Soto stay that blends convenience with budget-friendly rates—book now!

  Call (855) 235-0725 to book with an agent.
  24.2 miles from DE Soto, WI 54624

Starting at

$49.99

per night

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Adriatic

3438 Mormon Coulee Rd La Crosse, WI

Guests traveling to De Soto will enjoy the affordable comfort at Adriatic, where rooms start at $52.99, creating a warm, inviting atmosphere for relaxation. Stay in a room that balances comfort and practicality, providing dependable amenities for a pleasant visit.

Discover a calming atmosphere at Adriatic, where you can enjoy peaceful surroundings while keeping De Soto easily within reach. Plan your De Soto experience with a practical, budget-conscious hotel—book now!

  Call (855) 233-7850 to book with an agent.
  24.3 miles from DE Soto, WI 54624

Starting at

$52.99

per night

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Country Inn & Suites by Radisson Prairie du Chien WI

1801 Cabela's Lane Prairie Du Chien, WI

Experience the warmth and relaxation offered at Country Inn & Suites by Radisson Prairie du Chien WI near De Soto, where inviting rooms start from a budget-friendly $78.99 per night. Relax in the cozy ambiance of Country Inn & Suites’ indoor heated pool, a year-round leisure option for all guests.

Find a peaceful hideaway at Country Inn & Suites by Radisson Prairie du Chien WI, where you can unwind after exploring the bustling streets of De Soto. Plan a seamless De Soto stay with accommodations that put your comfort first—book today!

  Call (855) 233-0132 to book with an agent.
  24.5 miles from DE Soto, WI 54624

Starting at

$78.99

per night

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Gundersen Hotel & Suites

1520 Clinic Court La Crosse, WI

At Gundersen Hotel & Suites, guests bound for De Soto will find cozy-like comfort with rooms starting at $149.99, creating a warm, inviting environment perfect for rest. Stay in accommodations that deliver a richer experience with added amenities, ensuring a satisfying and budget-friendly visit.

Relax at Gundersen Hotel & Suites, where restful lodgings are matched with the convenience of having De Soto's highlights nearby. Find a hotel in De Soto that checks all the boxes for a great stay—book today!

  Call (855) 233-0132 to book with an agent.
  25.6 miles from DE Soto, WI 54624

Starting at

$149.99

per night

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Waterfront Hotel

113 South Main St Prairie Du Chien, WI

Relax at Waterfront Hotel as you explore De Soto, where quality rooms provide a peaceful stay, with budget-friendly nightly rates from $143.10. Find comfort in rooms that are designed with attention to detail, offering enhanced amenities for a superior stay.

Escape to Waterfront Hotel, where the peaceful atmosphere provides a break from the hustle, yet De Soto remains easily reachable. Relax and unwind in De Soto with a hotel that provides superior comfort and convenience—book today!

  Call (855) 235-6136 to book with an agent.
  26.1 miles from DE Soto, WI 54624

Starting at

$143.10

per night

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Fairfield Inn & Suites by Marriott La Crosse Downtown

434 3rd St. South La Crosse, WI

For a welcoming and budget-friendly stay, Fairfield Inn & Suites by Marriott La Crosse Downtown offers inviting rooms with rates from $169.99, creating a welcoming space ideal for travelers bound for De Soto. Relax with Fairfield's nightly guest receptions, offering complimentary snacks and a chance to meet other travelers.

Guests at Fairfield Inn & Suites by Marriott La Crosse Downtown will appreciate the calm surroundings, with De Soto's vibrant offerings only a short drive away. Treat yourself to a seamless De Soto adventure with affordable, welcoming lodging—secure now!

  Call (855) 233-7850 to book with an agent.
  26.4 miles from DE Soto, WI 54624

Starting at

$169.99

per night

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Cobblestone Inn & Suites Marquette / Prairie du Chien

100 North Street Marquette, IA

Guests visiting De Soto can unwind at Cobblestone Inn & Suites Marquette / Prairie du Chien, where welcoming accommodations start at $106.99, creating a welcoming and comfortable environment for rest. Find a cozy and affordable stay in rooms that provide a comfortable sleeping environment and basic conveniences.

Recharge in the comfort of Cobblestone Inn & Suites Marquette / Prairie du Chien, where guests can unwind in peace while keeping De Soto within reach for exploration. Make your De Soto experience exceptional with a hotel that keeps costs down—lock in today!

  Call (855) 236-8982 to book with an agent.
  26.5 miles from DE Soto, WI 54624

Starting at

$106.99

per night

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Courtyard by Marriott La Crosse

500 Front St. S La Crosse, WI

Explore a warm retreat at Courtyard by Marriott La Crosse near De Soto, where inviting accommodations offer quality and relaxation, with nightly rates starting from $159.99. Indulge in the convenience of room service at Courtyard, offering a range of tasty meals delivered directly to your room.

Guests seeking both rest and excitement will love Courtyard by Marriott La Crosse, where peaceful lodgings are paired with proximity to De Soto. Find unmatched comfort and style for your De Soto travels—book your hotel room today!

  Call (855) 234-5074 to book with an agent.
  26.5 miles from DE Soto, WI 54624

Starting at

$159.99

per night

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Home2 Suites by Hilton La Crosse

210 Jay Street La Crosse, WI

Find comfort and convenience at Home2 Suites by Hilton La Crosse near De Soto, with restful rooms offering a mellifluous ambiance for travelers, with rates beginning at $148.99. Keep up with your fitness goals at Spin2 Cycle, where you can work out while running laundry, a multitasking fitness center.

At Home2 Suites by Hilton La Crosse, guests can recharge in peaceful surroundings and still have the option to explore the sights of De Soto. Get the relaxation you deserve during your De Soto trip with inviting accommodations—book today!

  Call (855) 235-6136 to book with an agent.
  26.6 miles from DE Soto, WI 54624

Starting at

$148.99

per night

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Radisson Hotel La Crosse

200 Harborview Plaza La Crosse, WI

Experience quality and relaxation at Radisson Hotel La Crosse near De Soto, where inviting rooms create a welcoming escape, with affordable rates starting at $122.20. Refresh in Radisson's swimming pools, whether you prefer an invigorating morning swim or a leisurely afternoon by the water.

Settle into spacious comfort at Radisson Hotel La Crosse, where you can enjoy a quiet atmosphere and still take a quick trip into De Soto. Take advantage of an elegant De Soto stay with a hotel that makes guest service a priority—book today!

  Call (855) 233-0132 to book with an agent.
  26.7 miles from DE Soto, WI 54624

Starting at

$122.20

per night

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Trickling Waters Retreat

516 5th St. Court Marquette, IA

Unwind in the inviting atmosphere of Trickling Waters Retreat near De Soto, where welcoming rooms provide comfort and quality, with budget-friendly rates from $79.00. Stay in rooms that are designed to provide more than just the basics, with added features that make your stay special.

Step away from the fast pace of life and enjoy the serene atmosphere of Trickling Waters Retreat, with De Soto always close enough for a visit. Make every moment of your De Soto trip feel special with top-tier amenities—book today!

  Call (855) 234-5074 to book with an agent.
  26.7 miles from DE Soto, WI 54624

Starting at

$79.00

per night

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The Charmant Hotel

101 State St. La Crosse, WI

Explore upscale surroundings at The Charmant Hotel near De Soto, where quality rooms provide a relaxing retreat, with budget-friendly rates beginning at $189.99. Relax in the lap of luxury, where rooms are designed to provide an indulgent experience with every modern convenience.

At The Charmant Hotel, you’ll find the ideal base for rest and relaxation, with the vibrant life of De Soto nearby for exploration. Relax in De Soto with accommodations that transform comfort into a luxury experience—lock in today!

  Call (855) 233-0132 to book with an agent.
  26.8 miles from DE Soto, WI 54624

Starting at

$189.99

per night

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Hampton Inn & Suites La Crosse Downtown

511 3rd St. N. La Crosse, WI

With affordable rooms beginning at $141.99, Hampton Inn & Suites La Crosse Downtown provides budget-conscious comfort for guests bound for De Soto, creating a welcoming atmosphere. Earn points with Hilton Honors when you stay at Hampton, and enjoy exclusive benefits that make travel more rewarding.

Experience a calm retreat at Hampton Inn & Suites La Crosse Downtown, situated just a drive away from the vibrant offerings of De Soto. Step into De Soto with confidence, knowing your hotel delivers more for less—reserve now!

  Call (855) 239-4019 to book with an agent.
  27.0 miles from DE Soto, WI 54624

Starting at

$141.99

per night

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GrandStay Hotel & Suites

525 Front St. North La Crosse, WI

For a relaxing and budget-conscious stay near De Soto, GrandStay Hotel & Suites offers inviting accommodations with rooms starting at $109.00, creating a warm space for rest. Stay in accommodations that cater to your comfort with additional features, ensuring a pleasant and affordable visit.

At GrandStay Hotel & Suites, you’ll find the ideal base for rest and relaxation, with the vibrant life of De Soto nearby for exploration. Revel in added perks and comfort for your De Soto stay without breaking the bank—lock in today!

  Call (855) 236-8982 to book with an agent.
  27.0 miles from DE Soto, WI 54624

Starting at

$109.00

per night

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Hatchery Riverside Hotel & Event Venue

410 East Veterans Memorial Dr La Crosse, WI

At Hatchery Riverside Hotel & Event Venue, guests visiting De Soto can enjoy restful, affordable rooms starting at $213.99, creating a clean and inviting environment for a peaceful stay. Enjoy a stay that's designed for the practical traveler, with rooms that offer necessary comforts and a welcoming atmosphere.

Relax and recharge at Hatchery Riverside Hotel & Event Venue, where restful accommodations are paired with easy access to De Soto's downtown fun. Make your De Soto experience enjoyable without the high cost—reserve today!

  Call (855) 234-5074 to book with an agent.
  27.1 miles from DE Soto, WI 54624

Starting at

$213.99

per night

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Candlewood Suites La Crosse N an IHG Hotel

50 Copeland Ave La Crosse, WI

With rates beginning at $174.00, Candlewood Suites La Crosse N an IHG Hotel is an ideal choice for travelers visiting De Soto, creating a enveloping and welcoming space for relaxation. The 24-hour front desk at Candlewood Suites ensures that assistance is just a call away, anytime.

Find your ideal balance at Candlewood Suites La Crosse N an IHG Hotel, where guests can experience the tranquility of the surroundings while De Soto stays close by. Plan your De Soto travels with a hotel that’s designed for comfort and savings—secure now!

  Call (855) 234-2997 to book with an agent.
  27.4 miles from DE Soto, WI 54624

Starting at

$174.00

per night

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Microtel Inn & Suites by Wyndham Prairie du Chien

1833 South Marquette Road Prairie Du Chien, WI

With rooms starting at $83.99, Microtel Inn & Suites by Wyndham Prairie du Chien provides inviting comfort for guests bound for De Soto, creating a welcoming, welcoming environment perfect for unwinding. Choose Microtel for a refreshing and streamlined lodging experience, where comfort and convenience come together beautifully.

At Microtel Inn & Suites by Wyndham Prairie du Chien, guests can rest in a peaceful setting while keeping De Soto's best attractions within easy reach. Enjoy your De Soto adventure with accommodations designed for relaxation—book now!

  Call (855) 236-8982 to book with an agent.
  27.7 miles from DE Soto, WI 54624

Starting at

$83.99

per night

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Rodeway Inn

614 Monitor Street La Crosse, WI

For budget-savvy travelers visiting De Soto, Rodeway Inn offers inviting rooms with rates starting at $47.99, creating a intimate-feeling, comfortable environment ideal for rest. Experience practical comfort in a setting that focuses on providing essential amenities at an affordable price.

Discover the convenience of Rodeway Inn, a peaceful location with De Soto's attractions accessible whenever you're ready to explore. Enjoy De Soto adventures in comfort without breaking the bank—secure your stay today!

  Call (855) 234-5074 to book with an agent.
  27.7 miles from DE Soto, WI 54624

Starting at

$47.99

per night

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Windsor Place Inn

1936 Marquette Rd. South Prairie Du Chien, WI

At Windsor Place Inn, travelers to De Soto will find soft accommodations with rates beginning at $69.99, creating a warm, inviting space perfect for relaxation. Experience practical comfort in a setting that focuses on value and essential amenities, ideal for economical travels.

At Windsor Place Inn, guests can experience a relaxing stay while enjoying easy access to De Soto’s exciting attractions. Stay comfortably and spend less while exploring De Soto—book your room now!

  Call (855) 235-6136 to book with an agent.
  27.8 miles from DE Soto, WI 54624

Starting at

$69.99

per night

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Quality Inn & Suites

37268 US Highway 18 Prairie Du Chien, WI

At Quality Inn & Suites, travelers to De Soto will find budget-friendly rooms with rates starting at $73.99, creating a clean, welcoming environment perfect for rest. Appreciate the peace of mind provided by Quality Inn's emergency response plans, ensuring your safety throughout your stay.

Enjoy the calm atmosphere of Quality Inn & Suites, where a relaxing stay is paired with convenient access to De Soto. Plan your De Soto visit with a hotel that offers comfort without compromise—secure today!

  Call (855) 234-7135 to book with an agent.
  27.8 miles from DE Soto, WI 54624

Starting at

$73.99

per night

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