Top 24 Hotels In Depew, New York 14043

Buffalo Airport Hotel provides a welcoming retreat for travelers to Depew, with heartwarming accommodations starting from an accessible $156.38 per night. Enjoy accommodations that offer a bit more luxury and convenience, with rooms that are equipped to enhance your experience.

With downtown Depew only a brief drive from Buffalo Airport Hotel, guests can explore the city’s top destinations while staying in a quieter area. Relax in style in Depew with a hotel that delivers on both luxury and value—reserve your room now!

At TownePlace Suites Buffalo Airport, travelers to Depew will find budget-friendly comfort with rooms beginning at $199.99, creating a clean and inviting environment. Enhanced cleaning protocols at TownePlace Suites ensure a safe and comfortable environment.

With downtown Depew only a short drive away, guests at TownePlace Suites Buffalo Airport can experience the city’s best sights while staying in a quieter, more relaxed area. Relax in Depew with lodging that offers comfort and cost savings—reserve your room today!

Stay affordably at Comfort Inn & Suites Buffalo Airport as you journey to Depew, where appealing rooms offer a peaceful escape, with room rates starting at just $188.99. Choose Comfort Inn for family travel, with accommodations and amenities designed to make stays comfortable for guests of all ages.

From Comfort Inn & Suites Buffalo Airport, a brief drive brings guests into downtown Depew, where the city’s most popular spots are easily accessible. Get ready for a Depew stay that’s as comfortable as it is memorable—lock in today!

For a calm stay, Fairfield Inn & Suites by Marriott Buffalo Airport offers inviting rooms with rates starting at $199.99, creating a warm, welcoming atmosphere perfect for travelers bound for Depew. Experience Fairfield’s dedication to a restful night's sleep with their menu of pillow choices, catering to various comfort preferences.

With downtown Depew just a short drive away, guests at Fairfield Inn & Suites by Marriott Buffalo Airport can easily visit the city’s most vibrant spots while staying in a more peaceful location. Enjoy stress-free Depew travel with accommodations designed for relaxation and savings—book today!

Unwind in the tranquil setting of The Delavan Hotel & Spa as you visit Depew, where quality rooms offer a peaceful retreat, with inviting rates beginning at $214.99. Enjoy rooms that are a testament to refined luxury, featuring sumptuous furnishings and comprehensive, state-of-the-art facilities.

At The Delavan Hotel & Spa, a quick drive takes guests into downtown Depew, where the city’s best attractions are just a few minutes away. Get the most out of your Depew travels with accommodations that offer the highest standard—book today!

Find a warm retreat at Aloft Buffalo Airport as you explore Depew, where quality rooms provide comfort and relaxation, with inviting nightly rates beginning at $189.99. Participate in Aloft's unique pop-up events, which bring local culture, fashion, and art directly to guests in an interactive setting.

With downtown Depew only a brief drive away, guests at Aloft Buffalo Airport can explore the city’s best attractions while enjoying a quieter stay. Relax in Depew with a hotel that makes your visit feel effortless and enjoyable—secure now!

Choose Courtyard Buffalo Airport for a peaceful escape near Depew, where inviting accommodations provide relaxation and warmth, with rates beginning at just $209.99. Benefit from the quiet comfort of Courtyard's soundproof rooms, ensuring that your rest and relaxation are undisturbed.

Guests staying at Courtyard Buffalo Airport are never far from the action, with downtown Depew only a brief drive away for easy exploration. Stay affordably in Depew with a hotel that makes quality and savings a priority—lock in today!

At Sleep Inn & Suites Buffalo Airport, travelers bound for Depew will find alluring rooms with rates beginning at $120.99, creating a warm and welcoming space ideal for relaxation. Discover Sleep Inn's commitment to sustainability, from energy-efficient lighting to water-conserving fixtures in every room.

At Sleep Inn & Suites Buffalo Airport, guests are close enough to downtown Depew for a quick drive to the city’s top attractions, while still enjoying a quieter setting. Embrace added comfort and convenience while exploring Depew—book your hotel now!

Choose Hilton Garden Inn Buffalo Airport for your journey to Depew, where delightful rooms provide a welcoming experience, with inviting rates beginning at $190.99 per night. Unwind at the end of the day with Hilton Garden Inn's in-room entertainment options, including HDTVs and premium channels.

At Hilton Garden Inn Buffalo Airport, a quick drive delivers guests into the heart of downtown Depew, making it easy to explore the city’s best offerings. Take advantage of a Depew hotel that elevates your travel experience—lock in today!

At Hampton Inn & Suites Buffalo Airport, travelers to Depew will find delightful, budget-friendly rooms with rates starting at $135.99, creating a warm and inviting space for relaxation. Find cozy comfort in Hampton’s plush seating available in guest rooms, creating a perfect spot for reading or relaxing.

Guests staying at Hampton Inn & Suites Buffalo Airport can quickly reach downtown Depew with a brief drive, where the city’s most exciting attractions are just minutes away. Maximize your Depew adventure with inviting, well-appointed lodging—secure your room now!

At Holiday Inn Express Hotel & Suites Buffalo Airport an IHG Hotel, guests traveling to Depew will find inviting accommodations with rooms starting at $159.00, creating a snug, welcoming environment perfect for rest. Discover the value of staying at Holiday Inn Express, where essential services and amenities are included without extra charges.

From Holiday Inn Express Hotel & Suites Buffalo Airport an IHG Hotel, a brief drive brings guests right into downtown Depew, where the city’s most iconic sights are easily accessible. Make your Depew visit memorable and stress-free with inviting amenities—lock in today!

Relax in the comfort of Homewood Suites by Hilton Buffalo Airport near Depew, where quality accommodations create a intimate-feeling experience, with budget-friendly rates from $186.99. Enjoy a touch of luxury with Homewood Suites' designer toiletries and plush towels, adding comfort to your daily routine.

At Homewood Suites by Hilton Buffalo Airport, a brief drive brings guests into downtown Depew, making it easy to explore the city’s vibrant offerings while returning to a quieter retreat. Find the perfect blend of comfort and affordability for your Depew adventure—book today!

At Extended Stay America Suites Buffalo Airport, guests bound for Depew can enjoy inviting accommodations with rates starting at $199.99, creating a warm and welcoming environment. Stay engaged with Extended Stay America’s organized activities, including fitness classes and local outings.

Guests at Extended Stay America Suites Buffalo Airport can enjoy the convenience of being just a short drive from downtown Depew, making it easy to explore the city’s top destinations. Make your Depew experience exceptional with a hotel that keeps costs down—lock in today!

For a reassuring, budget-friendly stay, Baymont by Wyndham Buffalo offers inviting rooms with rates from $126.98, creating a clean and comfortable atmosphere near Depew. Experience the comfort of Baymont by Wyndham’s air-conditioned rooms, ensuring a cool and comfortable environment.

From Baymont by Wyndham Buffalo, a quick drive brings guests right into the heart of downtown Depew, perfect for exploring the city’s vibrant spots. Maximize your Depew adventure with well-rounded, cost-effective accommodations—secure now!

Those traveling to Depew will find Garden Place Hotel a charming choice, where refined rooms offer comfort, with nightly rates starting at an affordable $138.55. Relax in accommodations that blend sophisticated design with ultimate comfort, creating a uniquely luxurious experience.

At Garden Place Hotel, guests can quickly drive into downtown Depew, where the city’s most vibrant spots are within easy reach. Step into a Depew hotel where guest satisfaction is always top of mind—secure your room now!

For a relaxed and inviting stay, La Quinta Inn by Wyndham Buffalo Airport offers budget-friendly accommodations with rates from $144.40, creating a warm and comfortable environment. Enjoy a smooth check-in experience at La Quinta by Wyndham, where friendly staff are ready to greet you with a smile.

La Quinta Inn by Wyndham Buffalo Airport offers the perfect location for those wanting to visit downtown Depew, where a brief drive brings them to the city’s best spots. Maximize your Depew travels with a cost-effective, comfortable hotel stay—reserve today!

Guests traveling to Depew will enjoy the comfortable accommodations at Hospitality Inn Buffalo Airport, with rooms beginning at $110.00, creating a warm, inviting space perfect for rest. Relax in accommodations that balance comfort and convenience, offering everything you need for a worry-free stay.

At Hospitality Inn Buffalo Airport, guests are just a short drive away from downtown Depew, offering quick access to the city’s most popular attractions. Choose a welcoming, budget-friendly hotel for your Depew visit—book today!

For guests visiting Depew, Red Roof Inn Buffalo Niagara Airport offers budget-friendly comfort with rooms starting at $113.99, creating a clean and inviting atmosphere for relaxation. Choose Red Roof Inn for its combination of comfort, convenience, and value, ensuring a satisfying stay for all types of travelers.

With downtown Depew only a brief drive away, guests at Red Roof Inn Buffalo Niagara Airport can easily explore the city’s top attractions while staying in a quieter location. Stay comfortably and save more while enjoying Depew—lock in your hotel now!

Relax in style at Home2 Suites by Hilton Williamsville Buffalo Airport as you visit Depew, where comfortable rooms create a welcoming retreat, with budget-friendly rates starting at $164.99. Appreciate the convenience of Home2 Suites' Spin2 Cycle, where you can work out while running a load of laundry.

With downtown Depew only a short drive from Home2 Suites by Hilton Williamsville Buffalo Airport, guests can visit the city’s most vibrant spots while staying in a more peaceful location. Discover the perfect Depew retreat with accommodations that exceed expectations—lock in today!

At Tru by Hilton Williamsville Buffalo Airport, guests visiting Depew will find inviting comfort with rooms starting at $177.99, creating a clean and welcoming environment ideal for rest. Experience the eco-friendly initiatives at Tru by Hilton, from energy-efficient lighting to water-saving fixtures.

Tru by Hilton Williamsville Buffalo Airport is ideally positioned for travelers who want to be close to downtown Depew, where the city’s most vibrant spots are just a short drive away. Stay worry-free in Depew with a hotel that offers all the essentials at a great price—lock in now!

Unwind at Eva Hotel Buffalo Airport Best Western Signature Collection when traveling to Depew, where inviting rooms create a enveloping environment, with affordable nightly rates from $151.99. Experience Best Western’s attention to detail, from impeccably maintained facilities to personalized guest services.

From Eva Hotel Buffalo Airport Best Western Signature Collection, guests can easily access downtown Depew by car, making it simple to visit the city’s best attractions while returning to a more tranquil setting. Enjoy every aspect of your Depew trip with a hotel that delivers on quality—secure now!

At Motel 6 Buffalo NY Airport Williamsville, travelers to Depew will find inviting accommodations with rooms starting at $109.99, creating a harmonious and welcoming space ideal for relaxation. Benefit from the convenience of locations situated near major highways and popular attractions, making Motel 6 a smart choice for road trippers.

From Motel 6 Buffalo NY Airport Williamsville, a quick drive brings guests right into the heart of downtown Depew, perfect for exploring the city’s vibrant spots. Choose an inviting, affordable hotel for your Depew trip—secure your stay now!

Guests traveling to Depew will appreciate the inviting comfort at Best Western Buffalo Inn & Suites, where comforting rooms start at $154.00, creating a welcoming space for rest. Savor the moment in Best Western's outdoor spaces, from gardens to patios, offering a serene setting to unwind.

Guests at Best Western Buffalo Inn & Suites can enjoy the convenience of a short drive into downtown Depew, making it easy to explore the city’s best sights and return to a quieter retreat. Discover how great Depew can be with accommodations that keep you comfortable—secure now!

Guests traveling to Depew will find budget-friendly comfort at Tru by Hilton Williamsville Buffalo Airport, with inviting rooms starting at $178.95, creating a relaxed and welcoming space. Enjoy the lively energy of Tru by Hilton’s public spaces, featuring fun and engaging amenities like pool tables and board games.

Tru by Hilton Williamsville Buffalo Airport offers a convenient location for those looking to visit downtown Depew, where the city’s top spots are just a quick drive away. Stay comfortably and affordably while soaking in the best of Depew—reserve now!