Top 24 Hotels In Effingham, South Carolina 29541

Discover a relaxing stay at Hyatt Place Florence Downtown near Effingham, where inviting rooms provide warmth and quality, with room rates beginning at just $179.00 per night. Dine in or take away at Hyatt Place's dining options, offering everything from quick snacks to full meals depending on your schedule.

The relaxing setting of Hyatt Place Florence Downtown is perfect for guests who want to unwind, with downtown Effingham still within reach for easy city access. Make the most of your Effingham experience with a hotel that caters to your every need—reserve now!

With affordable rooms starting at $50.99, Super 8 by Wyndham Florence SC I-95 North / Hwy 76 provides budget-friendly comfort for travelers to Effingham, creating a welcoming environment for rest and ease. Earn points with every stay by joining Super 8’s Wyndham Rewards, where your loyalty is rewarded with exciting perks.

From Super 8 by Wyndham Florence SC I-95 North / Hwy 76, guests can easily drive into downtown Effingham, where they can explore the city’s highlights before returning to the calm of the hotel. Stay affordably and enjoy extra perks on your Effingham adventure—book now!

Stay affordably at Hotel Florence Tapestry Collection by Hilton on your journey to Effingham, where peaceful rooms create a peaceful escape, with budget-friendly rates beginning at $163.99. Explore local attractions with insights from Tapestry Collection's knowledgeable staff, enhancing your understanding of the area.

The peaceful setting of Hotel Florence Tapestry Collection by Hilton is perfect for unwinding, with downtown Effingham still within reach for easy access to the city’s highlights. Step into an inviting Effingham stay with a hotel that prioritizes your needs—book today!

Guests bound for Effingham can enjoy affordable comfort at Fairfield Inn & Suites by Marriott Florence I-20, with calm rooms starting at $179.99, creating a clean and inviting space for unwinding. Revel in the quiet comfort of Fairfield's rooms, designed to ensure a peaceful night's sleep with soundproofing and blackout curtains.

With Effingham still within easy reach by car, guests at Fairfield Inn & Suites by Marriott Florence I-20 can enjoy the best of the city while staying in a more peaceful location. Enjoy Effingham like never before with a hotel that’s practical and inviting—book today!

With rooms starting at $128.99, Comfort Inn & Suites provides budget-conscious accommodations for travelers bound for Effingham, creating a warm and inviting space. Opt for Comfort Inn, where you can expect a warm, inviting atmosphere and all the essentials for a memorable stay.

With downtown Effingham still within easy reach, guests at Comfort Inn & Suites can balance city adventures with the peaceful surroundings of the hotel. Plan your Effingham getaway with accommodations that make your stay seamless—reserve now!

Relax at Aloft Florence as you visit Effingham, where intimate-feeling rooms provide quality and warmth, with budget-friendly nightly rates starting at $154.99. Engage with the energetic vibe of Aloft's public spaces, designed for socializing, working, or just hanging out.

At Aloft Florence, guests can unwind in a peaceful environment, while downtown Effingham is still within easy reach for a day’s adventures. Enjoy a Effingham visit that’s as enjoyable as it is relaxing with exceptional lodging—reserve now!

For an affordable stay near Effingham, TownePlace Suites by Marriott Florence offers delightful rooms with rates from $204.99, creating a welcoming, comfortable atmosphere perfect for rest. Explore local attractions with ease, thanks to TownePlace Suites' convenient locations near popular sites and business districts.

Guests at TownePlace Suites by Marriott Florence will appreciate the tranquil atmosphere, with downtown Effingham just a drive away for easy access to the city’s top destinations. Uncover Effingham with a hotel that adds value to your adventure—reserve your stay now!

Experience tucked away accommodations at Home2 Suites by Hilton Florence SC when visiting Effingham, where quality meets comfort and value, with room rates starting from $138.99. Stay healthy with Home2 Suites' filtered water stations, available in gyms and public areas to keep you hydrated and refreshed.

At Home2 Suites by Hilton Florence SC, guests can recharge in quiet surroundings while keeping Effingham's best attractions close enough to explore. Get ready for a Effingham adventure with a hotel that adds value to your travels—book today!

Enjoy the peaceful ambiance of Residence Inn Marriott Florence on your trip to Effingham, where inviting rooms provide a relaxing escape, with budget-friendly rates from $214.99. Stay active with Residence Inn's recreational facilities, including fitness centers and sports courts, during your extended stay.

Relax and unwind at Residence Inn Marriott Florence, where spacious accommodations provide a peaceful environment while keeping Effingham close by. Unwind in Effingham with a hotel that combines elegance and budget-friendly rates—lock in today!

With rooms beginning at $125.99, Hilton Garden Inn Florence provides inviting accommodations for guests bound for Effingham, creating a welcoming, comfortable environment. Stay refreshed with a dip in Hilton Garden Inn's indoor or outdoor pool, an inviting space to relax or exercise.

Escape to Hilton Garden Inn Florence for a quiet retreat, where guests can relax in comfort while keeping Effingham's attractions nearby. Stay affordably and rest well in Effingham with a hotel that understands your needs—secure now!

For budget-savvy travelers to Effingham, Red Roof Inn Florence Civic Center provides inviting accommodations with rooms from $69.00, creating a intimate-feeling, comfortable space perfect for rest. Receive friendly and efficient service at Red Roof Inn, where guest satisfaction is a top priority.

The calm environment at Red Roof Inn Florence Civic Center creates a peaceful escape, with downtown Effingham close enough for all your adventures. Plan your Effingham trip wisely with budget-friendly, cozy accommodations—book now!

Experience a welcoming stay at Courtyard by Marriott Florence when visiting Effingham, where appealing rooms create a relaxing retreat, with nightly rates starting at $149.99. Customize your space with Courtyard's modular furniture in guest rooms, allowing you to adapt your environment to suit your needs and preferences.

From Courtyard by Marriott Florence, a brief drive brings guests into downtown Effingham, where they can explore the city’s top spots and return to the peace and quiet of their stay. Rest and recharge in Effingham at a hotel that offers a seamless blend of quality and affordability—lock in today!

Stay at SpringHill Suites by Marriott Florence for a restful visit to Effingham, where inviting accommodations create a welcoming environment, with affordable rates starting at just $152.99. Take advantage of SpringHill Suites' guest laundry facilities, providing an easy solution for longer stays.

Guests seeking tranquility can find it at SpringHill Suites by Marriott Florence, with downtown Effingham still close enough for a day of city adventures. Enjoy a well-deserved Effingham getaway with accommodations that exceed expectations—secure now!

Unwind in the cushy ambiance of Homewood Suites by Hilton Florence near Effingham, where inviting rooms provide quality and value, with nightly rates starting at $156.99. Start your day with Homewood Suites' complimentary hot breakfast, offering a variety of delicious options to fuel your morning.

From Homewood Suites by Hilton Florence, a relaxing drive brings guests into downtown Effingham, where they can explore the city’s attractions and return to the tranquility of the hotel. Get ready to enjoy Effingham with accommodations that offer both quality and value—lock in today!

For a restful stay near Effingham, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel offers budget-friendly accommodations with rooms starting at $144.00, creating a plush, welcoming atmosphere. Rely on the helpful staff at Holiday Inn Express, always ready to assist with recommendations, directions, and any other needs.

Unwind in the quiet atmosphere at Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel, knowing that downtown Effingham remains close enough for a day of adventure. Get ready for a Effingham adventure that’s both enjoyable and cost-effective—book today!

Encounter a warm retreat at Staybridge Suites Florence Civic Center an IHG Hotel near Effingham, where inviting rooms provide quality and relaxation, with nightly rates starting from just $194.00. Relish in the comfort and privacy of Staybridge Suites' suites, offering a peaceful retreat from the hustle and bustle of travel.

Travelers can unwind in the peaceful atmosphere of Staybridge Suites Florence Civic Center an IHG Hotel, while the attractions of downtown Effingham are a quick drive away. Relax and recharge in Effingham with accommodations that keep you feeling your best—reserve now!

For an affordable and comfortable stay, Hampton Inn & Suites Florence Center offers inviting rooms with rates starting at $151.99, creating a clean, welcoming environment for guests. Experience the comfort of adjustable air conditioning in Hampton’s guest rooms, ensuring your personal comfort no matter the weather.

Guests can relax at Hampton Inn & Suites Florence Center, where a peaceful atmosphere complements the convenience of nearby downtown Effingham. Enjoy an effortless Effingham adventure with budget-conscious, inviting lodging—book now!

At Days Inn by Wyndham Florence Near Civic Center, guests visiting Effingham will find inviting rooms with rates starting at $78.99, providing a clean and welcoming space perfect for relaxation. Enjoy the unique charm and character of each Days Inn location, reflecting the local culture and community.

Guests can enjoy the tranquility of Days Inn by Wyndham Florence Near Civic Center, while keeping downtown Effingham within reach for a day of sightseeing or adventure. Take advantage of thoughtful amenities and affordable rates for your Effingham trip—book today!

Guests visiting Effingham will find pleasant comfort at Quality Inn&Suites Civic, where budget-friendly rooms start at $95.99, creating a warm and inviting space perfect for relaxation. Benefit from Quality Inn's complimentary shuttle service, providing convenient transportation to nearby airports and attractions.

For travelers looking to relax, Quality Inn&Suites Civic offers quiet surroundings while keeping downtown Effingham within easy driving distance. Rest well in Effingham with accommodations that make relaxation affordable—lock in today!

At Baymont Inn & Suites Florence by Wyndham, travelers bound for Effingham will find inviting comfort with rooms beginning at $43.99, creating a clean and welcoming space perfect for relaxation. Start your day energized with Baymont by Wyndham’s fitness options, including gyms and in some locations, outdoor exercise areas.

For a serene getaway, Baymont Inn & Suites Florence by Wyndham provides the perfect setting, while keeping downtown Effingham within easy driving distance. Enjoy your Effingham getaway with peace of mind and budget-friendly amenities—reserve now!

For a comfortable and budget-friendly stay, Best Western Inn offers inviting rooms with rates beginning at $79.99, creating a gentle environment near Effingham. Enjoy the perks of Best Western's VIP programs, providing exclusive services and amenities to frequent travelers.

A stay at Best Western Inn offers calm surroundings and easy access to downtown Effingham, ensuring guests can enjoy both relaxation and exploration. Make your Effingham trip memorable with a hotel that offers more for less—secure your stay now!

At Super 8 by Wyndham Florence, guests bound for Effingham can enjoy sheltered, budget-friendly accommodations starting at $68.99, creating a warm and inviting space perfect for rest. Enjoy updates and modern touches in Super 8’s rooms, ensuring each guest enjoys contemporary comfort and style.

Escape to Super 8 by Wyndham Florence for a peaceful retreat, with the excitement of downtown Effingham still accessible for exploration. Enjoy enhanced comfort at a great price for your Effingham travels—secure now!

At Suburban Studios Florence I-95, travelers bound for Effingham will find delightful rooms starting at $56.99, creating a welcoming, comfortable environment perfect for a peaceful stay. Enjoy the essentials in rooms that deliver reliable amenities, ensuring a comfortable stay at a great price.

For a more peaceful stay, Suburban Studios Florence I-95 offers a calm atmosphere, with downtown Effingham just a convenient drive away. Make your Effingham adventure both comfortable and affordable—book now!

Guests traveling to Effingham will find Econo Lodge a easygoing, budget-conscious choice, with rooms beginning at $56.99, creating a welcoming environment ideal for relaxation. Look forward to a welcoming atmosphere at Econo Lodge, where the goal is to make every guest feel at home.

Guests staying at Econo Lodge will enjoy the quiet retreat, with downtown Effingham still nearby for all their city adventures. Stay smart and comfortable while keeping costs low on your Effingham visit—reserve now!