The best deals on hotels when visiting Enterprise in Missouri.

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Top 24 Hotels In Enterprise, Missouri 63437

Simple Rewards Inn Shelbina

711 North Highway 15 Shelbina, MO

For an affordable and cushy stay, Simple Rewards Inn Shelbina offers inviting rooms with rates beginning at $91.99, creating a clean and comfortable environment ideal for relaxation near Enterprise. Enjoy a worry-free stay with rooms that provide standard amenities and a welcoming environment, perfect for a comfortable visit.

Guests staying at Simple Rewards Inn Shelbina will enjoy the calm atmosphere, while downtown Enterprise remains nearby for a day of exploration. Enjoy added perks at a cost-effective rate on your Enterprise adventure—secure today!

  Call (855) 234-7135 to book with an agent.
  12.4 miles from Enterprise, MO 63437

Starting at

$91.99

per night

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Travelier Motel

201 East Briggs Dr Macon, MO

For those headed to Enterprise, Travelier Motel offers budget-friendly comfort with rooms starting at $70.00, creating a clean, welcoming environment perfect for unwinding. Stay in accommodations that offer a pleasant step up in amenities, making your stay both comfortable and economical.

Relax in the quiet environment of Travelier Motel, where guests can enjoy peaceful surroundings and downtown Enterprise remains nearby. Discover the ideal way to visit Enterprise with a hotel that values your comfort—secure now!

  Call (855) 239-5277 to book with an agent.
  13.2 miles from Enterprise, MO 63437

Starting at

$70.00

per night

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Super 8 by Wyndham Macon

203 East Briggs Dr Macon, MO

With rooms beginning at $86.99, Super 8 by Wyndham Macon is a convenient choice for travelers to Enterprise, providing budget-conscious comfort in a warm, inviting setting. Depend on the uniform quality and service of Super 8, where you can expect the same high standards across all locations.

With a brief drive into downtown Enterprise, guests at Super 8 by Wyndham Macon can balance the excitement of the city with the peaceful atmosphere of their stay. Stay relaxed and enjoy more of Enterprise with budget-friendly comfort—reserve today!

  Call (855) 239-5277 to book with an agent.
  13.2 miles from Enterprise, MO 63437

Starting at

$86.99

per night

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Americas Best Value Inn & Suites Macon at Sunset Dr

28933 Sunset Drive Macon, MO

For those bound for Enterprise, Americas Best Value Inn & Suites Macon at Sunset Dr offers inviting, budget-friendly accommodations with rooms beginning at $76.99, creating a welcoming space for all guests. Benefit from Americas Best Value Inn's no-frills approach to lodging, focusing on essential amenities and services.

Relax in the quiet atmosphere of Americas Best Value Inn & Suites Macon at Sunset Dr, where peaceful surroundings and proximity to downtown Enterprise combine for a perfect stay. Enjoy Enterprise to the fullest with inviting, budget-friendly lodging—book now!

  Call (855) 234-7135 to book with an agent.
  14.5 miles from Enterprise, MO 63437

Starting at

$76.99

per night

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Comfort Inn & Suites Moberly

1801 West Outer Rd Moberly, MO

With budget-conscious rooms starting at $103.99, Comfort Inn & Suites Moberly is an ideal choice for travelers to Enterprise, creating a heartwarming, welcoming space perfect for rest. Count on the friendly and professional service at Comfort Inn to enhance your stay, with staff ready to meet your every need.

A relaxing drive takes guests from Comfort Inn & Suites Moberly into downtown Enterprise, offering a blend of city adventure and tranquil retreat. Choose a hotel that enhances your Enterprise experience with thoughtful amenities—book today!

  Call (855) 235-0725 to book with an agent.
  16.8 miles from Enterprise, MO 63437

Starting at

$103.99

per night

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Super 8 by Wyndham Moberly MO

300 East Highway 24 Moberly, MO

Guests visiting Enterprise can unwind in inviting comfort at Super 8 by Wyndham Moberly MO, with rooms beginning at $78.99, creating a clean and welcoming atmosphere ideal for relaxation. Rely on Super 8 for a convenient, comfortable, and cost-effective stay, making it an ideal choice for budget-conscious travelers.

Guests staying at Super 8 by Wyndham Moberly MO can unwind in peaceful surroundings, with downtown Enterprise still a manageable drive for a day of adventure. Enjoy an affordable Enterprise stay that prioritizes your comfort—book your room now!

  Call (855) 234-2997 to book with an agent.
  17.0 miles from Enterprise, MO 63437

Starting at

$78.99

per night

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FairBridge Inn Express Monroe City

3 Gateway Sq. Drive Monroe City, MO

With rooms starting at $100.99, FairBridge Inn Express Monroe City provides inviting accommodations for travelers to Enterprise, creating a warm, welcoming environment ideal for relaxation. Experience a stay that's both economical and satisfying, with rooms that provide necessary amenities for a comfortable visit.

Relax at FairBridge Inn Express Monroe City, where restful lodgings are matched with the convenience of having Enterprise's highlights nearby. Stay cozy and within budget on your Enterprise adventure—lock in your room today!

  Call (855) 239-4019 to book with an agent.
  28.7 miles from Enterprise, MO 63437

Starting at

$100.99

per night

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The Junction Inn

28804 MO 19 Perry, MO

With rates beginning at $74.99, The Junction Inn is an ideal option for travelers visiting Enterprise, offering tranquil rooms that provide a welcoming, comfortable experience. Experience reliable comfort in rooms that offer all the essentials, making your stay both pleasant and budget-friendly.

Whether for work or leisure, The Junction Inn offers a balance of tranquility and easy access to Enterprise's major attractions. Stay affordably and experience added perks on your Enterprise trip—reserve your room now!

  Call (855) 234-7135 to book with an agent.
  36.5 miles from Enterprise, MO 63437

Starting at

$74.99

per night

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Hotel Marceline

101 West Ira Street Marceline, MO

At Hotel Marceline, guests traveling to Enterprise will find inviting accommodations with rooms starting at $84.99, creating a warm and comfortable environment. Find practical and affordable lodging, with rooms that offer clean accommodations and the essentials for a pleasant stay.

Unwind in the calm environment of Hotel Marceline, where city attractions are just a quick drive away for your convenience. Unlock the comfort you deserve on your Enterprise trip with affordable lodging—reserve now!

  Call (855) 235-6136 to book with an agent.
  36.7 miles from Enterprise, MO 63437

Starting at

$84.99

per night

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Baymont by Wyndham Kirksville University Area

2702 South Franklin Kirksville, MO

Guests visiting Enterprise will find pleasant comfort at Baymont by Wyndham Kirksville University Area, with inviting rooms starting at $73.99, creating a welcoming atmosphere ideal for rest. Stay energized with Baymont by Wyndham’s breakfast options, which include healthy and hearty choices to start your day right.

At Baymont by Wyndham Kirksville University Area, guests can enjoy spacious comfort in a peaceful environment while keeping Enterprise close at hand for exploration. Enjoy an effortless Enterprise adventure with budget-conscious, inviting lodging—book now!

  Call (855) 235-6136 to book with an agent.
  39.6 miles from Enterprise, MO 63437

Starting at

$73.99

per night

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Best Western Teal Lake Inn

3602 South Clark St Mexico, MO

With rooms starting at $88.99, Best Western Teal Lake Inn provides budget-conscious accommodations for travelers bound for Enterprise, creating a warm and inviting space. Relax with confidence, knowing Best Western offers a 100% satisfaction guarantee to address any concerns during your stay.

Step into a quiet retreat at Best Western Teal Lake Inn, offering serene surroundings just a short drive from the buzz of Enterprise. Stay in Enterprise with a hotel that caters to your needs and budget—secure your room now!

  Call (855) 236-8982 to book with an agent.
  39.7 miles from Enterprise, MO 63437

Starting at

$88.99

per night

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Days Inn by Wyndham Kirksville

3805 South Baltimore St Kirksville, MO

For an affordable and harmonious stay, Days Inn by Wyndham Kirksville offers inviting rooms with rates beginning at $74.99, creating a clean and comfortable environment ideal for relaxation near Enterprise. Explore local culture and attractions with Days Inn as your base, conveniently located to help you discover the best of each destination.

At Days Inn by Wyndham Kirksville, guests can recharge in a quiet setting while keeping Enterprise's excitement within reach for daily adventures. Stay comfortably and save on your Enterprise adventure—lock in your room today!

  Call (855) 236-8982 to book with an agent.
  39.7 miles from Enterprise, MO 63437

Starting at

$74.99

per night

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Holiday Inn Express & Suites Kirksville University Area an IHG Hotel

2523 South Franklin St. Kirksville, MO

At Holiday Inn Express & Suites Kirksville University Area an IHG Hotel, travelers visiting Enterprise will find inviting accommodations with rooms from $149.00, creating a warm and welcoming space ideal for rest. Savor the moment at Holiday Inn Express's coffee stations, serving freshly brewed coffee throughout the day for a quick pick-me-up.

At Holiday Inn Express & Suites Kirksville University Area an IHG Hotel, the inviting atmosphere ensures relaxation, with downtown Enterprise always within an easy drive. Make your Enterprise travels enjoyable and worry-free with well-appointed, budget-friendly lodging—secure now!

  Call (855) 235-6136 to book with an agent.
  39.8 miles from Enterprise, MO 63437

Starting at

$149.00

per night

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Days Inn by Wyndham Mexico

2902 South Clark Mexico, MO

With rooms starting at $89.99, Days Inn by Wyndham Mexico is a practical choice for travelers headed to Enterprise, providing a clean, inviting space for relaxation. Begin each morning with our delicious and complimentary breakfast buffet, full of both hot and cold options to suit every taste.

Find your peaceful getaway at Days Inn by Wyndham Mexico, where you can unwind in quiet comfort while Enterprise's attractions are never far away. Enjoy reliable, comfortable lodging that fits your budget in Enterprise—secure now!

  Call (855) 239-5277 to book with an agent.
  39.9 miles from Enterprise, MO 63437

Starting at

$89.99

per night

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Amerihost Inn & Suites Mexico

900 Vance Rd Mexico, MO

With rooms starting at $60.99, Amerihost Inn & Suites Mexico provides budget-conscious accommodations for travelers visiting Enterprise, creating a clean and pleasant space. Stay in rooms that offer the basics for a comfortable stay, with efficient service and a focus on guest satisfaction.

At Amerihost Inn & Suites Mexico, you’ll find the ideal base for rest and relaxation, with the vibrant life of Enterprise nearby for exploration. Treat yourself to an affordable, inviting hotel experience in Enterprise—book today!

  Call (855) 234-7135 to book with an agent.
  41.6 miles from Enterprise, MO 63437

Starting at

$60.99

per night

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Quality Inn Kirksville

2209 North Baltimore St Kirksville, MO

For an affordable and welcoming stay near Enterprise, Quality Inn Kirksville offers budget-friendly rooms with rates from $80.99, creating a clean and comfortable atmosphere. Feel the warmth of Quality Inn's hospitality, with staff committed to providing a memorable and comfortable stay.

Stay at Quality Inn Kirksville for a restful experience, where the peaceful ambiance is complemented by the proximity to Enterprise's highlights. Stay comfortably in Enterprise without sacrificing quality or savings—lock in your hotel today!

  Call (855) 236-8982 to book with an agent.
  42.7 miles from Enterprise, MO 63437

Starting at

$80.99

per night

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Sleep Inn & Suites

105 Lakeside Dr Hannibal, MO

With rates beginning at $115.99, Sleep Inn & Suites is ideal for guests visiting Enterprise, offering calm accommodations in a welcoming, clean environment. Appreciate Sleep Inn's eco-friendly initiatives, aiming to reduce environmental impact through sustainable practices.

Unwind in comfort at Sleep Inn & Suites, where guests are treated to peaceful surroundings with Enterprise's highlights just a short trip away. Plan your Enterprise visit with confidence, knowing your hotel has everything you need—lock in today!

  Call (855) 233-7850 to book with an agent.
  43.7 miles from Enterprise, MO 63437

Starting at

$115.99

per night

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Best Western Brookfield

28622 Highway 11 Brookfield, MO

For travelers headed to Enterprise, Best Western Brookfield offers inviting rooms with rates starting at $138.99, creating a clean and welcoming environment perfect for relaxation. Celebrate your special events at Best Western, with catering and event planning services to ensure a memorable occasion.

Discover the quiet charm of Best Western Brookfield, a restful escape found just a short drive from the excitement of Enterprise. Unwind in Enterprise with a hotel that caters to your needs and budget—secure your stay today!

  Call (855) 233-7850 to book with an agent.
  44.0 miles from Enterprise, MO 63437

Starting at

$138.99

per night

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Quality Inn & Suites Hannibal

120 Lindsey Drive Hannibal, MO

Guests bound for Enterprise can enjoy budget-friendly comfort at Quality Inn & Suites Hannibal, where soft rooms start at $93.99, creating a welcoming space perfect for relaxation. Choose Quality Inn for your next travel destination, where you'll find excellent value, comfort, and a satisfying stay.

Stay at Quality Inn & Suites Hannibal for a peaceful retreat, while keeping the exciting opportunities in Enterprise close at hand. Enjoy your Enterprise visit with a hotel that combines convenience and value perfectly—lock in today!

  Call (855) 233-7850 to book with an agent.
  44.1 miles from Enterprise, MO 63437

Starting at

$93.99

per night

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Howard Johnson by Wyndham Hannibal

4141B MARKET ST Hannibal, MO

For those visiting Enterprise, Howard Johnson by Wyndham Hannibal offers budget-friendly accommodations with rooms from $64.99, creating a comfortable, inviting atmosphere. Appreciate all-inclusive rates that cover all the essentials, from breakfast to Wi-Fi, ensuring a great stay without additional charges.

Stay at Howard Johnson by Wyndham Hannibal for a restful experience, where the calm setting ensures relaxation with Enterprise's attractions nearby. Enjoy the beauty of Enterprise with a hotel that keeps your budget intact—book today!

  Call (855) 234-7135 to book with an agent.
  45.5 miles from Enterprise, MO 63437

Starting at

$64.99

per night

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Days Inn by Wyndham Hannibal

4070 Market St Hannibal, MO

For guests bound for Enterprise, Days Inn by Wyndham Hannibal offers quiet rooms with rates starting at $61.20, creating a clean, welcoming environment ideal for relaxation. Keep up with your fitness in our on-site gyms, featuring modern equipment and a supportive environment.

Recharge at Days Inn by Wyndham Hannibal, where a quiet stay is complemented by the convenience of Enterprise nearby for daily adventures. Enjoy more of Enterprise for less with budget-friendly, inviting hotel rooms—book now!

  Call (855) 234-5074 to book with an agent.
  45.5 miles from Enterprise, MO 63437

Starting at

$61.20

per night

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Baymont by Wyndham Hannibal

4141 Market St Hannibal, MO

For a comfortable and inviting stay, Baymont by Wyndham Hannibal offers delightful rooms with rates beginning at $66.99, creating a clean and comfortable space near Enterprise. Enjoy a night in with Baymont by Wyndham’s in-room movie rentals, offering a selection of the latest releases.

Stay at Baymont by Wyndham Hannibal for a peaceful escape, with the bonus of being close to Enterprise's lively streets for daily adventures. Experience Enterprise without overspending with a hotel that enhances your visit—lock in now!

  Call (855) 236-8982 to book with an agent.
  45.5 miles from Enterprise, MO 63437

Starting at

$66.99

per night

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Comfort Inn & Suites Hannibal

4000 Market St Hannibal, MO

With rates beginning at $95.99, Comfort Inn & Suites Hannibal provides inviting accommodations for travelers visiting Enterprise, creating a charming, welcoming space for relaxation. Benefit from valuable local knowledge, with staff recommendations on dining, shopping, and entertainment options.

Enjoy the best of both worlds at Comfort Inn & Suites Hannibal, where guests can relax in peace while keeping Enterprise close enough for exploration. Relax and enjoy Enterprise with a hotel that keeps comfort affordable—lock in now!

  Call (855) 234-2997 to book with an agent.
  45.6 miles from Enterprise, MO 63437

Starting at

$95.99

per night

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Super 8 by Wyndham Hannibal

120 Huckleberry Heights Dr Hannibal, MO

With budget-friendly rooms starting at $67.99, Super 8 by Wyndham Hannibal is a practical choice for travelers bound for Enterprise, creating a warm-hearted and inviting space perfect for relaxation. Find Super 8 locations conveniently close to everything from scenic highways to vibrant city centers, enhancing your travel plans.

At Super 8 by Wyndham Hannibal, guests are welcomed into a peaceful environment while keeping the sights of Enterprise just a drive away. Plan ahead for an affordable and relaxing Enterprise stay—book your hotel room today!

  Call (855) 239-5277 to book with an agent.
  46.4 miles from Enterprise, MO 63437

Starting at

$67.99

per night

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