Top 24 Hotels In Florence, South Carolina 29505

Explore affordable comfort at Hyatt Place Florence Downtown as you journey to Florence, where intimate rooms and quality service await, with rates beginning at $179.00. Indulge in the convenience and taste of Hyatt Place's in-room dining options, delivering delicious meals directly to your door.

At Hyatt Place Florence Downtown, a quick drive brings guests into downtown Florence, where the city’s most popular attractions are easily accessible. Find your home away from home in Florence with a hotel that caters to your needs—reserve now!

Enjoy a peaceful atmosphere at Hotel Florence Tapestry Collection by Hilton as you journey to Florence, where restful accommodations provide comfort, with budget-friendly rates starting at $163.99. Relax with pet-friendly accommodations at select Tapestry Collection hotels, welcoming your furry companions to join the adventure.

With downtown Florence just a short drive away, guests at Hotel Florence Tapestry Collection by Hilton can explore the city’s most vibrant spots while staying in a quieter location. Discover how great Florence can be with accommodations that go above and beyond—lock in today!

With budget-friendly rooms from $179.99, Fairfield Inn & Suites by Marriott Florence I-20 provides inviting comfort for travelers visiting Florence, creating a warm, welcoming space. Explore the local area with ease, thanks to Fairfield's knowledgeable staff who are ready to provide recommendations and directions.

At Fairfield Inn & Suites by Marriott Florence I-20, a quick drive takes guests into the heart of downtown Florence, making it simple to experience the city’s most vibrant offerings. Stay smart and relaxed in Florence with a hotel that fits your budget perfectly—lock in today!

Guests bound for Florence can enjoy secure comfort at TownePlace Suites by Marriott Florence, where rooms start at $224.99, creating a welcoming environment ideal for relaxation. Every suite at TownePlace Suites features a fully equipped kitchen, making it easy to cook meals during your stay.

TownePlace Suites by Marriott Florence offers a great location for those wanting to visit Florence, where downtown is just a short drive away for convenient access to the city’s top spots. Enjoy Florence from a hotel that enhances your travel experience—lock in now!

With rates starting at $69.00, Red Roof Inn Florence Civic Center offers budget-friendly accommodations for travelers headed to Florence, creating a enveloping space ideal for relaxation. Find versatile lodging options at Red Roof Inn, accommodating everything from solo business trips to family vacations.

With downtown Florence only a short drive away, guests at Red Roof Inn Florence Civic Center can explore the city’s top attractions while enjoying a quieter setting. Enjoy added value and comfort on your Florence trip—book your stay now!

Choose Courtyard by Marriott Florence for your journey to Florence, where soft rooms offer a comfortable escape, with rates beginning at an inviting $149.99 per night. Choose Courtyard by Marriott for your next trip, where modern amenities and attentive service ensure a balanced and fulfilling travel experience.

From Courtyard by Marriott Florence, a brief drive brings guests into downtown Florence, where the city’s most iconic spots await exploration. Plan your Florence adventure with a hotel that keeps your comfort top of mind—reserve now!

For a relaxing and affordable stay, Hilton Garden Inn Florence offers budget-friendly rooms with rates from $125.99, creating a clean and comfortable environment for guests visiting Florence. Spend an evening relaxing in Hilton Garden Inn's outdoor patio areas, equipped with fire pits and comfortable seating for a perfect night under the stars.

With downtown Florence only a short drive from Hilton Garden Inn Florence, guests can visit the city’s top destinations while staying in a quieter location. Choose a hotel that takes your Florence experience to the next level—book now!

Stay comfortably at SpringHill Suites by Marriott Florence as you explore Florence, where inviting accommodations and comfortable rooms start from a welcoming $152.99 per night for added relaxation. Relax knowing SpringHill Suites places a high priority on cleanliness and safety, with enhanced measures for a worry-free stay.

From SpringHill Suites by Marriott Florence, a quick drive brings guests into the heart of downtown Florence, making it easy to explore the city’s best offerings. Relax and rejuvenate in Florence with a hotel that offers well-rounded amenities—book today!

Find a tucked away getaway at Residence Inn Marriott Florence as you visit Florence, where inviting rooms offer comfort and quality, with rates starting from an accessible $214.99. Experience the convenience of in-suite dining at Residence Inn, with room service options that cater to your schedule.

At Residence Inn Marriott Florence, a quick drive delivers guests into the heart of downtown Florence, where the city’s top destinations are just minutes away. Discover how enjoyable Florence can be with accommodations that make every dollar count—book today!

For a reassuring and inviting stay, Comfort Inn & Suites offers budget-friendly accommodations with rates from $128.99, creating a warm and comfortable environment. Relax in Comfort Inn's tastefully decorated lobbies, offering a welcoming space to unwind or meet up with friends.

Comfort Inn & Suites is perfectly positioned for guests wanting to explore downtown Florence, where a brief drive brings them to the city’s best spots. Get ready for a Florence stay that’s as comfortable as it is affordable—reserve your room now!

At Hampton Inn & Suites Florence Center, guests bound for Florence can unwind in cozy-like accommodations with rooms starting at $151.99, creating a warm, welcoming atmosphere. Opt for enhanced comfort with upgraded bedding options available in select Hampton rooms, featuring premium linens for a luxurious sleep.

With downtown Florence just a brief drive from Hampton Inn & Suites Florence Center, guests can easily explore the city’s most iconic attractions while staying in a quieter setting. Rest easy in Florence with a hotel that offers all the essentials at a great rate—book now!

Experience the inviting atmosphere of Aloft Florence near Florence, where comfortable rooms offer quality and warmth, with budget-friendly rates starting at $154.99. Unwind in Aloft's ultra-comfortable rooms, featuring plush platform beds, walk-in showers, and urban-inspired decor.

With downtown Florence just a short drive from Aloft Florence, guests can enjoy the best of the city while staying in a quieter, more peaceful location. Choose a hotel in Florence that transforms your stay into a delightful experience—lock in today!

Relax in the welcoming atmosphere of Home2 Suites by Hilton Florence SC on your visit to Florence, where serene rooms provide comfort and quality, with room rates starting at $138.99 per night. Unwind in Home2 Suites' saline swimming pools, a chemical-free option for relaxation and recreation.

Guests staying at Home2 Suites by Hilton Florence SC are never far from the action, with downtown Florence only a brief drive away for easy exploration. Get ready for an extraordinary Florence visit with accommodations that enhance your trip—book today!

For a restful stay, Days Inn by Wyndham Florence Near Civic Center offers relaxing accommodations with rates from $77.99, creating a welcoming space ideal for travelers visiting Florence. Relax in Days Inn's modern lobbies, perfect spaces for reading, working, or planning your day's activities.

From Days Inn by Wyndham Florence Near Civic Center, a brief drive delivers guests to downtown Florence, where the city’s best attractions are easily reachable. Unlock the comfort you deserve on your Florence trip with affordable lodging—reserve now!

For a comfortable stay near Florence, Quality Inn&Suites Civic offers budget-conscious rooms with rates beginning at $95.99, creating a safe, inviting space for relaxation. Stay productive with Quality Inn's in-room workspaces, designed to accommodate the needs of business travelers.

From Quality Inn&Suites Civic, a brief drive delivers guests to downtown Florence, where the city’s most popular destinations await exploration. Stay comfortably in Florence and let the savings add to your adventure—book now!

With budget-friendly rooms beginning at $144.00, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel is a practical choice for travelers to Florence, creating a welcoming and comfortable space. Take advantage of Holiday Inn Express's signature Pancake Machine for a fun and easy breakfast experience.

With downtown Florence only a short drive away, guests at Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel can explore the city’s top destinations without staying in the busiest parts of town. Rest easy in Florence with a hotel that prioritizes your relaxation and budget—book today!

Relax in the homely ambiance of Homewood Suites by Hilton Florence as you journey to Florence, where quality rooms offer comfort, with budget-friendly rates from $156.99. Relax with the convenience of Homewood Suites' in-room dining service, offering delicious meals delivered directly to your door.

From Homewood Suites by Hilton Florence, a brief drive delivers guests to downtown Florence, where the city’s most popular attractions are easily reachable. Enjoy a Florence stay where your comfort is always the top priority—book your accommodations today!

At Best Western Inn, guests traveling to Florence will find delightful, budget-friendly rooms starting at $79.99, creating a clean and welcoming environment for relaxation. Take a relaxing stroll through Best Western's garden courtyards, beautifully maintained as peaceful retreats from the bustling city.

With downtown Florence just a short drive from Best Western Inn, guests can easily explore the city’s most popular sights while returning to a quieter setting. Take the guesswork out of Florence travel with a hotel that delivers on value—lock in today!

Find restful accommodations at Staybridge Suites Florence Civic Center an IHG Hotel on your journey to Florence, where heartwarming rooms offer relaxation, with nightly rates beginning at an accessible $191.96. Explore Staybridge Suites by IHG, a brand that combines the comforts of home with the conveniences of hotel living for a unique stay experience.

Staybridge Suites Florence Civic Center an IHG Hotel provides the ideal base for those wanting to explore Florence, where the downtown area is always just a short drive from the hotel. Uncover a Florence hotel that offers unmatched service and modern amenities—lock in today!

At Baymont Inn & Suites Florence by Wyndham, travelers to Florence can unwind in inviting rooms with rates starting at $43.99, providing a clean and comfortable space ideal for relaxation. Start your day energized with Baymont by Wyndham’s fitness options, including gyms and in some locations, outdoor exercise areas.

At Baymont Inn & Suites Florence by Wyndham, guests can take advantage of the short drive to downtown Florence, where they can explore the city’s vibrant offerings with ease. Find your ideal Florence hotel with amenities that make your visit extra special—lock in today!

At Super 8 by Wyndham Florence, guests traveling to Florence can enjoy affordable rooms starting at $68.99, providing a warm-hearted, inviting environment ideal for relaxation. Stay refreshed with Super 8's available laundry facilities, a convenient option for travelers on extended trips.

Guests staying at Super 8 by Wyndham Florence will love the convenience of being close to downtown Florence, where the city’s most popular destinations are just a short drive away. Enjoy Florence without the high cost—reserve a cozy, affordable room now!

With rates starting at $56.99, Suburban Studios Florence I-95 is a practical choice for travelers visiting Florence, providing a warm and inviting atmosphere for rest. Stay in a room that balances comfort and practicality, providing dependable amenities for a pleasant visit.

From Suburban Studios Florence I-95, a short drive takes guests right into the bustling downtown area of Florence, offering easy access to the city’s best offerings. Stay affordably and comfortably while visiting Florence—reserve your room today!

For budget-conscious guests visiting Florence, Econo Lodge offers easygoing accommodations with rates starting at $56.99, creating a warm and welcoming environment. Find Econo Lodge locations conveniently near major thoroughfares, ideal for road trippers and those looking to explore the surrounding area.

Econo Lodge offers an ideal location for guests wanting to explore Florence, where a short drive delivers them to the city’s most popular destinations. Plan ahead and enjoy a cozy, budget-friendly stay for your Florence visit—reserve now!

For a welcoming stay near Florence, Clarion Inn & Suites offers intimate-feeling, budget-friendly rooms with rates starting at $47.99, creating a comfortable environment. Experience the convenience of onsite laundry facilities at Clarion Inn, ideal for long stays or when you need fresh clothes in a hurry.

At Clarion Inn & Suites, guests can easily access downtown Florence, where the city’s top attractions are always within easy reach by car. Make your Florence trip stress-free and comfortable with a budget-friendly hotel—lock in now!