Top 24 Hotels In Hillsborough, North Carolina 27278

Guests headed to Hillsborough will appreciate the sheltered accommodations at Microtel Inn & Suites by Wyndham Hillsborough, where rooms begin at $89.10, creating a clean and welcoming space perfect for rest. Join the Wyndham Rewards program during your stay at Microtel, earning points towards free nights and exclusive benefits.

Microtel Inn & Suites by Wyndham Hillsborough gives guests the perfect location to explore downtown Hillsborough, where the city’s most popular destinations are just minutes away. Enjoy Hillsborough in comfort and without the expense—lock in your stay today!

For an affordable and restful stay, Holiday Inn Express Hillsborough an IHG Hotel offers inviting accommodations with rates beginning at $154.00, creating a homely atmosphere near Hillsborough. Stay entertained with Holiday Inn Express's game room, featuring billiards, video games, and more for guest enjoyment.

With Hillsborough’s downtown area just minutes away, guests at Holiday Inn Express Hillsborough an IHG Hotel can easily explore the city’s best attractions while enjoying a peaceful stay. Enjoy the best of Hillsborough with a hotel that puts your comfort first—lock in your room now!

Guests bound for Hillsborough can relax at OYO Hotel Durham West Hills, where inviting rooms start at $51.99, creating a warm and welcoming environment ideal for unwinding. Experience enhanced comfort with rooms that offer added amenities, ensuring a relaxing and convenient stay at a great value.

From OYO Hotel Durham West Hills, guests can drive into downtown Hillsborough, where they can explore the city’s most popular spots before retreating to a peaceful stay. Stay worry-free in Hillsborough with a hotel that offers all the essentials at a great price—lock in now!

Enjoy elevated comfort at Hilton Durham near Duke University as you explore Hillsborough, where inviting rooms create a warm stay, with budget-friendly rates from $193.99. Savor the moment in Hilton's beautifully appointed public spaces, where architecture and art come together to create inspiring environments.

From Hilton Durham near Duke University, a brief drive takes guests into downtown Hillsborough, where they can explore the city’s top spots and return to a quieter stay afterward. Unwind in Hillsborough with a hotel that offers a perfect mix of relaxation and luxury—secure now!

Guests headed to Hillsborough can relax at SureStay Plus Hotel by Best Western Durham Medical Center, where budget-friendly rooms start at $68.99, creating a warm and inviting atmosphere ideal for unwinding. Celebrate your special events at Best Western, with catering and event planning services to ensure a memorable occasion.

Guests at SureStay Plus Hotel by Best Western Durham Medical Center will appreciate the calm atmosphere of the hotel, with downtown Hillsborough still accessible by car for a day of city exploration. Enjoy your Hillsborough trip with accommodations that add value and comfort—book today!

With affordable rooms beginning at $204.99, Hampton Inn & Suites Durham University Medical Center provides inviting accommodations for guests bound for Hillsborough, creating a clean, comfortable space. Experience the comfort of adjustable air conditioning in Hampton’s guest rooms, ensuring your personal comfort no matter the weather.

Hampton Inn & Suites Durham University Medical Center offers the ideal setting for guests seeking peace and quiet, with downtown Hillsborough only a short trip away for a day of exploring. Enjoy more of Hillsborough with a practical hotel designed for your convenience—reserve now!

Choose Home2 Suites by Hilton Durham University Medical Center for a comfortable stay near Hillsborough, where inviting rooms create a relaxing environment, with room rates starting at $190.99 per night. Stay entertained with Home2 Suites' Smart HDTVs in every suite, offering streaming capabilities and premium channels.

With a quick drive into downtown Hillsborough, guests at Home2 Suites by Hilton Durham University Medical Center can explore the city’s best spots while retreating to a quieter, more relaxing stay. Relax in Hillsborough with a hotel that takes your comfort seriously, without breaking the bank—lock in today!

Guests bound for Hillsborough can unwind in affordable comfort at Days Inn by Wyndham Durham / Near Duke University, with homely rooms starting at $78.99, creating a welcoming, relaxing space. Enjoy a vibrant stay at Days Inn, where we combine bright décor with exceptional service for a memorable experience.

From Days Inn by Wyndham Durham / Near Duke University, the drive into downtown Hillsborough is simple, allowing guests to enjoy the city’s top spots while staying in a more relaxed environment. Stay affordably and comfortably while exploring the best of Hillsborough—lock in your room today!

Millennium Durham offers travelers to Hillsborough a welcoming option, with quality accommodations designed for relaxation, with rates starting from just $114.00 per night. Relax in accommodations that offer a variety of modern amenities, ensuring a comfortable and enjoyable stay.

From Millennium Durham, a simple drive brings guests into downtown Hillsborough, where they can explore the city’s attractions before returning to a peaceful stay. Step into an unforgettable Hillsborough experience with a hotel that delivers exceptional value—book today!

Stay at Courtyard Durham Near Duke University / Downtown when traveling to Hillsborough, where restful rooms provide relaxation and quality, with affordable nightly rates from $161.99. Taste the local culture with Courtyard's themed dinner nights, offering special menus that highlight regional cuisines and traditions.

With downtown Hillsborough a drive from Courtyard Durham Near Duke University / Downtown, guests can explore the city’s top spots while enjoying a more relaxed stay away from the bustle. Unwind in Hillsborough with a hotel that brings added convenience to your journey—reserve now!

Uncover inviting accommodations at AC Hotel Durham on your journey to Hillsborough, where comforting rooms provide relaxation, with affordable rates beginning at $284.99. Rely on AC Hotels for strategically placed USB ports and power outlets in every room, ensuring all your devices are fully charged.

From AC Hotel Durham, a simple drive brings guests into downtown Hillsborough, where they can explore the city’s attractions before returning to a peaceful stay. Discover how enjoyable Hillsborough can be with a hotel that offers everything you need—lock in today!

Guests bound for Hillsborough will find appealing comfort at Comfort Inn & Suites Durham near Duke University, with inviting rooms starting at $129.99, creating a warm and welcoming space perfect for relaxation. Stay refreshed with Comfort Inn's air-conditioned rooms, ensuring a comfortable environment no matter the weather.

At Comfort Inn & Suites Durham near Duke University, visitors can enjoy the relaxing surroundings of the hotel, while downtown Hillsborough is just a convenient drive away for easy exploration. Experience Hillsborough with peace of mind, knowing your hotel delivers value—secure now!

Relax in the comfortable ambiance of Residence Inn by Marriott Chapel Hill when traveling to Hillsborough, where restful accommodations offer relaxation, with room rates from $339.99. Reserve a room at Residence Inn and benefit from exceptional comfort and outstanding customer service during your stay.

Guests at Residence Inn by Marriott Chapel Hill will love how close they are to downtown Hillsborough, where a quick drive brings them to the city’s top destinations. Step into your Hillsborough travels with a hotel that makes your stay effortless—book today!

Unwind in the elegance of JB Duke Hotel as you travel to Hillsborough, where quality accommodations ensure a luxurious stay, with budget-friendly rates starting at $233.99. Enjoy the privilege of rooms that combine modern luxuries with timeless elegance, providing a lavish and comfortable stay.

At JB Duke Hotel, guests can enjoy the calm of being outside the city center, while downtown Hillsborough is still conveniently accessible by car. Discover the beauty of Hillsborough with a hotel that adds a touch of grandeur to your visit—secure now!

At Red Roof Inn Chapel Hill UNC, travelers to Hillsborough can enjoy inviting rooms with rates from $116.00, creating a warm and welcoming environment perfect for relaxation. Relax in the peaceful, well-appointed rooms at Red Roof Inn, designed to provide comfort and tranquility during your stay.

Guests staying at Red Roof Inn Chapel Hill UNC will appreciate the quiet surroundings, with downtown Hillsborough still accessible for a day of sightseeing and adventure. Make your Hillsborough adventure memorable and budget-wise—secure your hotel room now!

Step into elegance at Washington Duke Inn & Golf Club on your journey to Hillsborough, where tranquil rooms create a peaceful retreat, with inviting nightly rates starting at $272.99. Stay in luxurious surroundings that provide an escape from the ordinary, with rooms designed to offer every conceivable comfort.

Staying at Washington Duke Inn & Golf Club allows guests to retreat to a serene location, with downtown Hillsborough still within easy reach for a day’s adventures. Stay in Hillsborough with a hotel that offers the perfect blend of opulence and value—book today!

At Comfort Inn University Durham Chapel Hill, travelers to Hillsborough will find affordable comfort with rooms beginning at $156.99, creating a clean and welcoming environment for unwinding. Choose from a variety of room types, tailored to suit solo travelers, couples, and families alike.

The calm and quiet of Comfort Inn University Durham Chapel Hill is complemented by its proximity to downtown Hillsborough, just a drive away for easy access to the city’s attractions. Stay comfortably in Hillsborough without sacrificing quality or savings—lock in your hotel today!

Experience a welcoming stay at The Lodge at Duke Medical Center when visiting Hillsborough, where pleasant rooms create a relaxing retreat, with nightly rates starting at $139.99. Experience a stay that goes beyond the ordinary, with rooms equipped for comfort and convenience in a welcoming environment.

Guests staying at The Lodge at Duke Medical Center can enjoy easy access to downtown Hillsborough, where they can explore the city’s most popular destinations while enjoying a quieter stay. Discover the best way to unwind in Hillsborough with well-appointed, budget-friendly lodging—secure now!

With rates starting at $106.99, University Inn Durham next to Duke University Medical Center provides budget-conscious accommodations for guests visiting Hillsborough, creating a appealing and inviting space for relaxation. Enjoy a stay that focuses on providing the essentials, with rooms that are equipped for comfort and practicality.

Guests staying at University Inn Durham next to Duke University Medical Center can appreciate the quieter surroundings, with downtown Hillsborough still easily accessible for sightseeing and city exploration. Enjoy added value and comfort on your Hillsborough trip—book your stay now!

Find a relaxing retreat at Homewood Suites by Hilton Durham Chapel Hill / I-40 as you travel to Hillsborough, where easygoing rooms offer restful accommodations, with nightly rates beginning at $275.99. Enjoy seasonal activities at Homewood Suites, from summer pool parties to winter holiday events, enhancing your stay year-round.

At Homewood Suites by Hilton Durham Chapel Hill / I-40, guests can appreciate the balance of being far enough for quiet, while still close enough to downtown Hillsborough for a day of sightseeing. Experience Hillsborough like never before with well-appointed, budget-savvy accommodations—book today!

Guests headed to Hillsborough can relax at La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill, where budget-friendly rooms start at $345.99, creating a warm and inviting atmosphere ideal for unwinding. Enjoy a smooth check-in experience at La Quinta by Wyndham, where friendly staff are ready to greet you with a smile.

Unwind in the calm surroundings of La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill, where relaxation meets easy access to the vibrant energy of Hillsborough. Find the perfect Hillsborough escape with accommodations that don’t break the bank—lock in today!

At Red Roof Inn Durham Duke Univ Medical Center, guests traveling to Hillsborough can enjoy affordable rooms starting at $74.99, providing a friendly, inviting environment ideal for relaxation. Take advantage of the great outdoors at select Red Roof Inn locations, offering guests spaces to unwind in nature.

Enjoy tranquility at Red Roof Inn Durham Duke Univ Medical Center, where the calm surroundings provide a peaceful retreat while downtown Hillsborough remains nearby. Book a practical, inviting hotel for your Hillsborough experience and enjoy more—secure now!

For a welcoming stay near Hillsborough, Holiday Inn Express Durham an IHG Hotel offers appealing, budget-friendly rooms with rates starting at $174.00, creating a comfortable environment. Appreciate the attentive and personalized service at Holiday Inn Express, where staff are committed to ensuring your needs are met.

Guests staying at Holiday Inn Express Durham an IHG Hotel can enjoy a restful escape while still being close enough to downtown Hillsborough for sightseeing. Explore Hillsborough effortlessly with a hotel that offers exceptional value—reserve now!

At Extended Stay America Suites Durham University, travelers to Hillsborough will find budget-friendly rooms with rates beginning at $85.99, creating a welcoming and comfortable environment. Stay connected with Extended Stay America’s multiple device charging stations in each suite, keeping all your electronics powered up.

At Extended Stay America Suites Durham University, guests can enjoy the quiet environment, with downtown Hillsborough remaining nearby for all their city adventures. Enjoy Hillsborough to the fullest with accommodations that won’t strain your wallet—reserve today!