The best deals on hotels when visiting Hoffmeyer Crossroads in South Carolina.

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Top 24 Hotels In Hoffmeyer Crossroads, South Carolina 29501

Quality Inn&Suites Civic

150 Dunbarton Dr Florence, SC

Guests headed to Hoffmeyer Crossroads will find budget-friendly comfort at Quality Inn&Suites Civic, where relaxing rooms begin at $95.99, creating a welcoming atmosphere perfect for relaxation. Discover the convenience of Quality Inn's room service app, allowing you to order food and services directly from your smartphone.

Quality Inn&Suites Civic provides guests with an excellent base to explore Hoffmeyer Crossroads, where the downtown district is only minutes away. Stay smart and relaxed in Hoffmeyer Crossroads with value-driven amenities—book your room now!

  Call (855) 233-7850 to book with an agent.
  1.1 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$95.99

per night

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Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence, SC

Guests visiting Hoffmeyer Crossroads will find charming comfort at Days Inn by Wyndham Florence Near Civic Center, with rooms beginning at $78.99, creating a warm and inviting space ideal for rest. Stay refreshed with Days Inn's in-room refrigerators and microwaves, available in select rooms for your convenience.

Days Inn by Wyndham Florence Near Civic Center offers an excellent location for guests who want to be near downtown Hoffmeyer Crossroads, where the city’s most vibrant spots are within easy reach. Stay smart and relaxed in Hoffmeyer Crossroads with value-driven amenities—book your room now!

  Call (855) 233-0132 to book with an agent.
  1.1 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$78.99

per night

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Hampton Inn & Suites Florence Center

3000 West Radio Dr Florence, SC

For those bound for Hoffmeyer Crossroads, Hampton Inn & Suites Florence Center offers serene, budget-friendly accommodations with rates from $151.99, creating a comfortable space perfect for relaxation. Start your day energized with in-room coffee and tea facilities at Hampton, allowing you to brew your morning beverage just the way you like it.

At Hampton Inn & Suites Florence Center, you’re close enough to Hoffmeyer Crossroads’s center for a relaxed walk, but far enough to enjoy peace and quiet after a busy day. Embrace your Hoffmeyer Crossroads adventure with lodging that keeps comfort within reach—reserve today!

  Call (855) 236-8982 to book with an agent.
  1.1 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$151.99

per night

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SpringHill Suites by Marriott Florence

2670 Hospitality Blvd Florence, SC

Enjoy a comfortable stay at SpringHill Suites by Marriott Florence on your trip to Hoffmeyer Crossroads, where quality rooms provide a restful environment, with rates starting at $152.99. Refresh and rejuvenate in the thoughtfully designed bathrooms at SpringHill Suites, equipped with contemporary amenities.

SpringHill Suites by Marriott Florence provides guests with an excellent location for exploring Hoffmeyer Crossroads, where the downtown district’s most popular spots are just a short distance away. Enjoy a memorable Hoffmeyer Crossroads stay with a hotel that offers exceptional comfort and style—reserve now!

  Call (855) 235-6136 to book with an agent.
  1.3 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$152.99

per night

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Courtyard by Marriott Florence

2680 Hospitality Blvd Florence, SC

Relax in the tranquil surroundings of Courtyard by Marriott Florence when traveling to Hoffmeyer Crossroads, where quality rooms create an inviting atmosphere, with nightly rates from $149.99. Connect and collaborate in Courtyard's vibrant common areas, designed to encourage interaction and productivity among guests.

Guests at Courtyard by Marriott Florence are in a great position to explore Hoffmeyer Crossroads, with downtown just a short distance away and easily accessible on foot or by car. Plan your Hoffmeyer Crossroads visit with confidence, knowing your hotel offers unparalleled comfort—reserve now!

  Call (855) 239-4019 to book with an agent.
  1.3 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$149.99

per night

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Red Roof Inn Florence Civic Center

2690 David H McLeod Boulevard Florence, SC

Guests traveling to Hoffmeyer Crossroads will find affordable comfort at Red Roof Inn Florence Civic Center, where rooms begin at $69.00, providing a welcoming atmosphere ideal for a peaceful stay. Experience great value and clean accommodations at Red Roof Inn, where each stay is both affordable and enjoyable.

Red Roof Inn Florence Civic Center ensures that guests are always close to downtown Hoffmeyer Crossroads, where the city’s most exciting sights are just minutes away. Stay affordably and comfortably while visiting Hoffmeyer Crossroads—book your room now!

  Call (855) 235-6136 to book with an agent.
  1.3 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$69.00

per night

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Hilton Garden Inn Florence

2671 Hospitality Boulevard Florence, SC

Guests visiting Hoffmeyer Crossroads can enjoy affordable comfort at Hilton Garden Inn Florence, where charming rooms start at $125.99, creating a warm and inviting space ideal for unwinding. Choose Hilton Garden Inn for your next stay, where friendly service and comfortable accommodations await to make your visit memorable.

Hilton Garden Inn Florence gives guests the perfect mix of convenience and comfort, with downtown Hoffmeyer Crossroads just a short distance away. Discover how inviting and affordable your Hoffmeyer Crossroads trip can be—book your room today!

  Call (855) 235-6136 to book with an agent.
  1.4 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$125.99

per night

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Residence Inn Marriott Florence

2660 Hospitality Blvd Florence, SC

Unwind at Residence Inn Marriott Florence as you travel to Hoffmeyer Crossroads, where heartwarming accommodations offer a peaceful escape, with rates beginning at a welcoming $214.99 per night. Take a break in the cozy lounge areas at Residence Inn, ideal for casual meetings or relaxing with a book.

Residence Inn Marriott Florence provides guests with the perfect base to explore Hoffmeyer Crossroads, where the vibrant downtown area is just minutes away. Explore Hoffmeyer Crossroads worry-free with accommodations that ensure a smooth experience—book today!

  Call (855) 234-2997 to book with an agent.
  1.4 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$214.99

per night

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Homewood Suites by Hilton Florence

3450 West Radio Drive Florence, SC

Relax in the inviting comfort of Homewood Suites by Hilton Florence as you travel to Hoffmeyer Crossroads, where delightful rooms await at an affordable starting rate of $156.99 per night. Relax with in-suite massage services at Homewood Suites, a perfect indulgence during your extended stay.

Guests staying at Homewood Suites by Hilton Florence can easily reach downtown Hoffmeyer Crossroads, where the city’s most popular spots are always just a short journey from the hotel. Experience Hoffmeyer Crossroads with accommodations that make every moment memorable—book today!

  Call (855) 239-5277 to book with an agent.
  1.4 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$156.99

per night

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TownePlace Suites by Marriott Florence

2650 Hospitality Boulevard Florence, SC

For an affordable stay near Hoffmeyer Crossroads, TownePlace Suites by Marriott Florence offers inviting accommodations with rooms beginning at $204.99, creating a clean and comfortable space. Consider TownePlace Suites by Marriott for your next relocation or extended vacation, where you'll find all the comforts of home.

At TownePlace Suites by Marriott Florence, you’re never far from the excitement of downtown Hoffmeyer Crossroads, where the city’s most vibrant spots are just a short journey from the hotel. Plan your Hoffmeyer Crossroads visit with accommodations that make relaxation affordable—book today!

  Call (855) 234-2997 to book with an agent.
  1.5 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$204.99

per night

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Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel

3440 West Radio Dr Florence, SC

At Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel, travelers visiting Hoffmeyer Crossroads can enjoy inviting accommodations with rooms starting at $144.00, creating a warm, welcoming environment for rest. Appreciate the cleanliness and safety protocols at Holiday Inn Express, ensuring a worry-free and healthy stay for all guests.

Staying at Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel means guests are never far from downtown Hoffmeyer Crossroads, offering quick access to the city’s best sights and attractions. Experience a well-rounded Hoffmeyer Crossroads stay with amenities that keep you comfortable—reserve now!

  Call (855) 235-6136 to book with an agent.
  1.5 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$144.00

per night

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Staybridge Suites Florence Civic Center an IHG Hotel

150 Westpark Drive Florence, SC

Unwind in delightful surroundings at Staybridge Suites Florence Civic Center an IHG Hotel near Hoffmeyer Crossroads, where restful accommodations are designed with comfort in mind, with rates starting at $194.00 per night. Relax with Staybridge Suites' selection of pillows, offering various levels of firmness for your comfort.

Guests at Staybridge Suites Florence Civic Center an IHG Hotel can enjoy quick access to downtown Hoffmeyer Crossroads, making it easy to experience the city’s top sights while staying in a quieter area. Enjoy your Hoffmeyer Crossroads visit with a hotel that makes relaxation feel effortless—book today!

  Call (855) 235-6136 to book with an agent.
  1.5 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$194.00

per night

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Home2 Suites by Hilton Florence SC

900 Woody Jones Blvd Florence, SC

Enjoy quality accommodations at Home2 Suites by Hilton Florence SC on your trip to Hoffmeyer Crossroads, where restful rooms offer comfort, with nightly rates starting from a friendly $138.99. Relax with the added security of Home2 Suites' 24-hour staff and electronic key access to suites and hotel facilities.

From Home2 Suites by Hilton Florence SC, a short drive brings guests into the heart of downtown Hoffmeyer Crossroads, where the city’s most popular spots await discovery. Unwind in Hoffmeyer Crossroads with a hotel that brings added convenience to your journey—reserve now!

  Call (855) 234-2997 to book with an agent.
  1.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$138.99

per night

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Fairfield Inn & Suites by Marriott Florence I-20

501 Woody Jones Boulevard Florence, SC

With budget-friendly rooms beginning at $179.99, Fairfield Inn & Suites by Marriott Florence I-20 provides inviting accommodations for travelers visiting Hoffmeyer Crossroads, creating a heartwarming, welcoming environment. Discover the convenience of Fairfield's express check-in and check-out, making your travel experience smoother and more efficient.

Fairfield Inn & Suites by Marriott Florence I-20 offers a convenient location for those looking to visit downtown Hoffmeyer Crossroads, where the city’s best sights are just a brief drive away. Enjoy your Hoffmeyer Crossroads adventure with a hotel that’s all about great value—lock in today!

  Call (855) 233-7850 to book with an agent.
  1.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$179.99

per night

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Comfort Inn & Suites

527 Woody Jones Blvd Florence, SC

With rooms starting at $128.99, Comfort Inn & Suites provides budget-conscious accommodations for travelers visiting Hoffmeyer Crossroads, creating a clean and tucked away space. Join the Choice Privileges® rewards program during your stay at Comfort Inn, earning points towards free nights and other rewards.

From Comfort Inn & Suites, a short drive delivers guests to the heart of downtown Hoffmeyer Crossroads, where the city’s best attractions await. Find the perfect place to rest and refresh while visiting Hoffmeyer Crossroads—secure now!

  Call (855) 236-8982 to book with an agent.
  1.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$128.99

per night

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Aloft Florence

820 WOODY JONES BOULEVARD Florence, SC

Explore tranquil accommodations at Aloft Florence on your journey to Hoffmeyer Crossroads, where restful rooms create a welcoming environment, with rates beginning at $154.99. Maintain your fitness routine in the well-appointed Re:charge℠ gym at Aloft, featuring the latest equipment and a vibrant setting for your workouts.

Guests at Aloft Florence are only a short drive from downtown Hoffmeyer Crossroads, making it simple to enjoy the city’s top attractions while staying in a quieter area. Relax in style in Hoffmeyer Crossroads with a hotel that delivers on both luxury and value—reserve your room now!

  Call (855) 234-2997 to book with an agent.
  1.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$154.99

per night

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Park Inn by Radisson Florence SC

1729 Mandeville Road Florence, SC

With rates beginning at $128.99, Park Inn by Radisson Florence SC is an ideal choice for travelers visiting Hoffmeyer Crossroads, creating a delightful and welcoming space for relaxation. Relax with Radisson's pillow menu, allowing you to choose the perfect pillow for a personalized sleeping experience.

At Park Inn by Radisson Florence SC, a quick drive brings guests into downtown Hoffmeyer Crossroads, making it easy to explore the city’s best sights and return to a quieter stay. Take the guesswork out of your Hoffmeyer Crossroads stay with a hotel that delivers on value—secure now!

  Call (855) 235-6136 to book with an agent.
  2.5 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$128.99

per night

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Howard Johnson by Wyndham Florence

2038 West Lucas Street Florence, SC

Guests traveling to Hoffmeyer Crossroads will find Howard Johnson by Wyndham Florence a budget-friendly choice, with comfortable rooms starting at $79.99, creating a warm and relaxing environment. Experience the warmth and community of Howard Johnson, where guests are encouraged to connect, share stories, and create new friendships.

From Howard Johnson by Wyndham Florence, a short drive brings guests into the heart of downtown Hoffmeyer Crossroads, where the city’s most exciting spots are within easy reach. Make your Hoffmeyer Crossroads experience cost-effective and relaxing—secure your stay now!

  Call (855) 233-7850 to book with an agent.
  2.5 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$79.99

per night

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Hampton Inn & Suites Florence North I-95

1735 Stokes Road Florence, SC

With rooms starting at $134.99, Hampton Inn & Suites Florence North I-95 provides budget-conscious comfort for travelers visiting Hoffmeyer Crossroads, creating a calm, inviting space for relaxation. Catch up on work or plan your day in Hampton's comfortable lobby workstations, complete with charging stations and complimentary printing.

Staying at Hampton Inn & Suites Florence North I-95 ensures that guests are always close to downtown Hoffmeyer Crossroads, where a quick drive brings them right into the heart of the action. Enjoy the convenience of a well-located, affordable hotel while visiting Hoffmeyer Crossroads—book today!

  Call (855) 235-0725 to book with an agent.
  2.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$134.99

per night

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Country Inn & Suites by Radisson Florence SC

1739 Mandeville Rd Florence, SC

Guests bound for Hoffmeyer Crossroads can enjoy relaxing comfort at Country Inn & Suites by Radisson Florence SC, where rooms start at $150.99, creating a welcoming environment ideal for relaxation. Stay cozy by the fire in select Country Inn & Suites locations, offering a warm and inviting atmosphere during colder months.

From Country Inn & Suites by Radisson Florence SC, a short drive delivers guests into the heart of downtown Hoffmeyer Crossroads, where the city’s most exciting destinations are easily accessible. Enjoy Hoffmeyer Crossroads from a hotel that enhances your travel experience—lock in now!

  Call (855) 236-8982 to book with an agent.
  2.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$150.99

per night

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Motel 6 Florence SC

2004 West Lucas St Florence, SC

Guests visiting Hoffmeyer Crossroads will find budget-conscious comfort at Motel 6 Florence SC, with rooms beginning at $54.99, creating a warm and welcoming space for relaxation. Step into a world of practical accommodations at Motel 6, where no-frills lodging meets all your basic needs without complexity.

At Motel 6 Florence SC, guests are always close enough to downtown Hoffmeyer Crossroads for a quick drive, making it simple to explore the city’s top spots. Plan ahead and make your Hoffmeyer Crossroads stay enjoyable and affordable—lock in today!

  Call (855) 239-5277 to book with an agent.
  2.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$54.99

per night

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Tru by Hilton Florence I-95

2140 West Lucas Street Florence, SC

At Tru by Hilton Florence I-95, travelers to Hoffmeyer Crossroads can enjoy inviting accommodations with rates starting at $138.99, providing a welcoming, comfortable environment. Relax with the blackout curtains in each room at Tru by Hilton, ensuring darkness and privacy for a good night’s sleep.

From Tru by Hilton Florence I-95, a short drive delivers guests into downtown Hoffmeyer Crossroads, where the city’s top destinations await exploration. Step into a welcoming Hoffmeyer Crossroads stay with accommodations that blend comfort and affordability—reserve now!

  Call (855) 233-7850 to book with an agent.
  2.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$138.99

per night

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Comfort Suites Florence I-95

2120 West Lucas Street Florence, SC

For budget-savvy travelers, Comfort Suites Florence I-95 offers friendly comfort with rates beginning at $141.99, creating a warm and inviting atmosphere perfect for relaxation. Discover the fresh appeal of Comfort Suites' newly renovated properties, where contemporary design meets classic comfort.

At Comfort Suites Florence I-95, guests can enjoy the convenience of a brief drive into downtown Hoffmeyer Crossroads, making it simple to visit the city’s most popular destinations. Discover a hotel that makes your Hoffmeyer Crossroads adventure stress-free and enjoyable—reserve today!

  Call (855) 233-7850 to book with an agent.
  2.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$141.99

per night

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Suburban Studios Florence I-95

1914 West Lucas St Florence, SC

With rooms starting at $56.99, Suburban Studios Florence I-95 offers inviting accommodations for guests bound for Hoffmeyer Crossroads, creating a clean, sheltered atmosphere for unwinding. Find comfort in rooms that deliver reliable amenities, ensuring a pleasant stay at a budget-friendly price.

From Suburban Studios Florence I-95, guests can quickly reach downtown Hoffmeyer Crossroads by car, where the city’s most iconic attractions are always nearby. Choose a cost-effective, welcoming hotel for your Hoffmeyer Crossroads visit—book now!

  Call (855) 236-8982 to book with an agent.
  2.6 miles from Hoffmeyer Crossroads, SC 29501

Starting at

$56.99

per night

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