Top 24 Hotels In Isola, Mississippi 38754

At Americas Best Value Inn Indianola, travelers visiting Isola can unwind in inviting comfort with rooms starting at $55.99, creating a clean and welcoming environment. Enjoy the convenience and security of on-site parking at Americas Best Value Inn, enhancing your ease of travel.

For guests seeking both tranquility and city access, Americas Best Value Inn Indianola offers the best of both worlds, with downtown Isola within reach. Get ready for a Isola stay that’s as comfortable as it is affordable—reserve your room now!

With budget-friendly rooms from $66.99, Quality Inn provides inviting accommodations for guests visiting Isola, creating a quiet and welcoming atmosphere. Explore local dining and entertainment options with Quality Inn's prime locations, offering easy access to the best of each destination.

At Quality Inn, guests can relax in serene surroundings, with downtown Isola still a convenient drive away for a day of adventure. Plan your Isola trip with a hotel that guarantees comfort and affordability—reserve today!

Guests bound for Isola can enjoy affordable comfort at Super 8 by Wyndham Indianola, with rooms starting at $79.99, providing a welcoming and relaxing environment. Bring your pets along for the journey with Super 8's friendly pet policy, ensuring no family member is left behind.

For a peaceful retreat, Super 8 by Wyndham Indianola offers calm surroundings with the added bonus of downtown Isola still being nearby. Book now for a value-packed, comfortable stay while visiting Isola—secure today!

With rates starting at $155.99, Holiday Inn Express&Suites Greenville an IHG Hotel is ideal for guests traveling to Isola, providing safe accommodations in a warm and inviting environment. Discover the convenience of Holiday Inn Express locations, perfectly positioned for easy access to local business centers and leisure attractions.

Find a restful haven at Holiday Inn Express&Suites Greenville an IHG Hotel, where the quiet setting ensures a calm stay with Isola's attractions nearby. Enjoy an exceptional Isola stay with added perks at a budget-friendly price—reserve today!

For budget-savvy travelers to Isola, Econo Lodge Greenville provides inviting accommodations with rooms starting at $63.00, creating a intimate-feeling, comfortable space ideal for rest. Stay assured with enhanced cleaning measures at Econo Lodge, focusing on thorough sanitization for your health and safety.

Discover the tranquility of Econo Lodge Greenville, where guests can unwind while keeping the sights of Isola within easy reach. Enjoy added value and comfort on your Isola trip—book your stay now!

Guests visiting Isola will find affordable comfort at Americas Best Value Inn & Suites Greenville, where hospitable rooms begin at $52.99, creating a welcoming atmosphere ideal for a peaceful stay. Enjoy straightforward amenities at Americas Best Value Inn, designed to make your stay smooth and stress-free.

Take advantage of the peaceful atmosphere at Americas Best Value Inn & Suites Greenville, while staying close to Isola for dining, entertainment, and more. Make your Isola trip memorable and cost-effective—secure your room now!

Guests visiting Isola will find Days Inn by Wyndham Greenville MS a reassuring, budget-friendly option, with rates starting at $67.99, creating a clean and inviting environment. Relax in our well-appointed lobbies, perfect for casual meetings or simply enjoying a quiet moment with a complimentary newspaper.

Experience the tranquility of Days Inn by Wyndham Greenville MS, where a peaceful stay is complemented by the nearby attractions of Isola. Enjoy more of Isola for less with practical, cost-saving lodging—secure your stay today!

At Tru by Hilton Greenville, travelers to Isola will find calm rooms with rates starting at $175.99, creating a clean, welcoming space perfect for a relaxing stay. Stay connected with free high-speed Wi-Fi throughout Tru by Hilton, perfect for streaming, browsing, and staying in touch.

Unwind in comfort at Tru by Hilton Greenville, providing a serene getaway that remains conveniently connected to Isola. Get the most out of Isola with lodging that makes your visit effortless—reserve now!

Guests headed to Isola will find enchanting comfort at SureStay Plus Hotel by Best Western Greenwood, where inviting rooms start at $106.99, creating a welcoming environment ideal for relaxation. Rely on Best Western's 24-hour reception, ensuring help and hospitality are always available, day or night.

At SureStay Plus Hotel by Best Western Greenwood, guests can unwind in spacious surroundings while still being close to the vibrant life of Isola. Plan your Isola trip with confidence, knowing your hotel delivers comfort and value—lock in today!

At Comfort Suites Greenwood, guests visiting Isola can enjoy inviting accommodations with rates beginning at $169.00, creating a cozy-like and welcoming space. Savor the moment with Comfort Suites' premium coffee and tea selection, available in your suite for a refreshing morning or evening beverage.

Stay at Comfort Suites Greenwood for the perfect blend of peaceful surroundings and quick access to the cultural offerings of Isola. Discover the ideal way to visit Isola with a hotel that values your comfort—secure now!

Guests bound for Isola will appreciate the cushy comfort at Holiday Inn Express & Suites Greenwood an IHG Hotel, with budget-friendly rooms beginning at $179.99, creating a warm and inviting space. Benefit from Holiday Inn Express's strategic partnerships, offering guests discounts and access to local attractions and services.

Relax and recharge at Holiday Inn Express & Suites Greenwood an IHG Hotel, where a calm atmosphere ensures restful nights with Isola's vibrant streets nearby. Get the most out of your Isola stay with a hotel that’s all about value—lock in today!

With rooms starting at $150.99, Hampton Inn Greenwood provides inviting comfort for guests bound for Isola, creating a serene, welcoming environment perfect for unwinding. Experience the local culture with Hampton's carefully curated local guides, offering insider tips on the best dining, shopping, and attractions.

At Hampton Inn Greenwood, you’ll find the perfect escape from city life, with Isola's bustling attractions always just a short drive away. Step into a welcoming Isola stay that delivers on both comfort and savings—lock in today!

For guests headed to Isola, Americas Best Value Inn & Suites Greenwood offers soothing accommodations with rooms starting at $62.99, creating a warm and inviting space perfect for relaxation. Take advantage of the value-packed amenities at Americas Best Value Inn, including in-room microwaves and refrigerators in select rooms.

Escape to the comfort of Americas Best Value Inn & Suites Greenwood, a tranquil spot where guests can relax and still explore Isola with ease. Plan ahead and stay affordably while exploring Isola—reserve your hotel now!

At Motel 6 Greenwood MS, travelers to Isola can enjoy budget-friendly rooms starting at $67.99, providing a clean and welcoming environment perfect for a relaxing stay. Relax knowing Motel 6 is committed to eco-friendly practices, working to reduce its environmental impact.

Stay at Motel 6 Greenwood MS to experience a quiet atmosphere, where restful nights are balanced by the option to explore Isola. Enjoy Isola with a hotel that keeps you comfortable without the extra cost—reserve today!

For a budget-conscious and inviting stay near Isola, The Skylight offers gentle rooms with rates starting at $136.00, creating a clean and welcoming space ideal for relaxation. Relax in a space that provides all the essentials for a satisfying stay, emphasizing both comfort and value.

Travelers will love the serene setting at The Skylight, where peaceful accommodations offer a relaxing stay near Isola. Stay comfortably and keep your budget intact while visiting Isola—book your room now!

At Rodeway Inn, travelers bound for Isola will find serene, affordable rooms starting at $66.99, creating a clean, comfortable space perfect for relaxation. Relax in a practical space that offers basic comforts and a clean environment, making your stay both pleasant and affordable.

Guests will enjoy the calm surroundings at Rodeway Inn, with the vibrant streets of Isola never too far for exploration. Book now and enjoy extra comfort on your Isola adventure without the high cost!

For budget-savvy travelers headed to Isola, Hampton Inn Yazoo City offers intimate-feeling comfort with rooms starting at $128.99, creating a clean, inviting environment. Relax in Hampton's thoughtfully designed guest rooms, offering the cozy Hampton bed, work desk, and modern amenities for a restful stay.

Settle into comfort at Hampton Inn Yazoo City, where guests can recharge in a serene setting with the energy of Isola a short drive away. Stay affordably in Isola with a hotel that enhances your travel experience—reserve now!

For a comforting and budget-friendly stay, Econo Lodge Yazoo City offers comfortable rooms with rates from $75.99, creating a clean, welcoming environment near Isola. Choose Econo Lodge for its focus on providing essential services and amenities at a price that’s hard to beat.

At Econo Lodge Yazoo City, guests can experience a relaxing stay while enjoying easy access to Isola’s exciting attractions. Plan your Isola trip with savings and extra comfort—reserve your room now!

With budget-friendly rooms starting at $104.99, Days Inn by Wyndham Yazoo City is a practical choice for travelers bound for Isola, creating a inviting and inviting space perfect for relaxation. Depend on Days Inn for consistent comfort and service, offering an affordable stay without compromising on quality.

Discover a refreshing retreat at Days Inn by Wyndham Yazoo City, nestled at a comfortable distance from the energy and attractions of Isola. Stay relaxed and enjoy added comfort on your Isola trip—book your room today!

At Best Western Gateway Inn, travelers bound for Isola will find budget-friendly comfort with rooms starting at $119.99, creating a comforting, inviting environment for unwinding. Enjoy the eco-conscious approach of Best Western, utilizing solar panels and energy-efficient technologies at select properties.

Relax in the comfort of Best Western Gateway Inn, where a calm environment is perfectly balanced with quick access to Isola's activities. Make Isola travel simple with a hotel that provides convenience and savings—reserve now!

At Ruleville Inn by OYO, guests bound for Isola will find plush comfort with rooms starting at $47.99, creating a warm, inviting environment perfect for rest. Find value in accommodations that offer a bit more comfort and convenience, ensuring a pleasant and economical stay.

Recharge at Ruleville Inn by OYO, where a quiet stay is complemented by the convenience of Isola nearby for daily adventures. Make every moment in Isola count with a hotel that offers more for less—secure today!

With quality and comfort, Cotton House Cleveland a Tribute Portfolio Hotel is a refined choice near Isola, where inviting rooms offer relaxation, with nightly rates beginning at $229.99. Witness the seamless melding of historical elements with modern flair at each Tribute Portfolio hotel, enriching your travel experience.

Relax at Cotton House Cleveland a Tribute Portfolio Hotel, where peaceful accommodations make for a refreshing stay and Isola's attractions are always nearby. Discover the beauty of Isola with a hotel that offers an elevated travel experience—secure now!

Choose Lyric Hotel West End Ascend Hotel Collection for your trip to Isola, where inviting rooms provide a welcoming experience, with affordable nightly rates starting at $156.55. Experience a comfortable retreat in rooms that provide modern amenities and a relaxing atmosphere.

At Lyric Hotel West End Ascend Hotel Collection, you’ll find restful accommodations and the convenience of being close to Isola's most exciting destinations. Step into a world of comfort and savings on your Isola adventure—secure your room now!

Guests traveling to Isola will appreciate the inviting comfort at Quality Inn, where budget-friendly rooms start at $89.99, creating a warm, welcoming environment. Step into Quality Inn, where value meets comfort, ensuring a satisfying stay for every guest.

Relax at Quality Inn, where guests can unwind in comfort and venture into Isola at their leisure. Settle into Isola with a hotel that balances convenience and cost savings—lock in now!