The best deals on hotels when visiting Isom in Virginia.

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Top 24 Hotels In Isom, Virginia 24228

Sleep Inn & Suites

5625 Dickenson Hwy Clintwood, VA

With budget-friendly rooms from $103.99, Sleep Inn & Suites provides inviting comfort for travelers visiting Isom, creating a warm, welcoming space. Relax with Sleep Inn's plush bedding and soft linens, designed to ensure a restful night's sleep.

With downtown Isom just a short drive from Sleep Inn & Suites, guests can easily visit the city’s most iconic spots while staying in a quieter area. Find out how affordable and enjoyable your Isom visit can be—reserve your room now!

  Call (855) 234-2997 to book with an agent.
  2.7 miles from Isom, VA 24228

Starting at

$103.99

per night

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The Inn at Wise

110 East Main Street Wise, VA

Choose The Inn at Wise for a restful escape when traveling to Isom, where inviting rooms offer comfort and relaxation, with nightly rates from $98.99. Stay in rooms that redefine comfort with modern amenities and thoughtful design, ensuring a memorable visit.

For a relaxing stay, The Inn at Wise offers quiet surroundings while keeping downtown Isom accessible for a day of sightseeing. Discover how enjoyable Isom can be with accommodations that cater to your needs—secure now!

  Call (855) 233-0132 to book with an agent.
  15.9 miles from Isom, VA 24228

Starting at

$98.99

per night

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Best Western of Wise

124 Woodland Dr. SW Wise, VA

With affordable rooms beginning at $100.99, Best Western of Wise provides inviting accommodations for guests bound for Isom, creating a clean, comfortable space. Relax in Best Western’s mini-suites, offering a bit more space and privacy with a separate seating area.

Guests at Best Western of Wise will find a peaceful retreat, while downtown Isom remains easily accessible for sightseeing or city activities. Maximize your Isom experience with a hotel that prioritizes value and convenience—secure today!

  Call (855) 234-5074 to book with an agent.
  16.7 miles from Isom, VA 24228

Starting at

$100.99

per night

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Super 8 by Wyndham Norton VA

425 Wharton Way Ne Norton, VA

For an inviting, budget-friendly stay near Isom, Super 8 by Wyndham Norton VA offers comfortable rooms starting at $67.99, providing a clean, homely space ideal for relaxation. Enjoy great value without compromise at Super 8, offering budget-friendly rates alongside comfortable and clean accommodations.

For a quiet retreat, Super 8 by Wyndham Norton VA offers peaceful surroundings, with the convenience of downtown Isom remaining nearby for city access. Stay budget-wise while enjoying Isom in comfort—secure your hotel today!

  Call (855) 239-4019 to book with an agent.
  18.8 miles from Isom, VA 24228

Starting at

$67.99

per night

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Days Inn by Wyndham Norton

375 Wharton Ln Ne Norton, VA

With rooms starting at $79.99, Days Inn by Wyndham Norton provides affordable, inviting accommodations for guests traveling to Isom, creating a safe and welcoming space. Experience the joy of travel with Days Inn's family-friendly services, including accommodations that cater to the needs of younger guests.

Guests at Days Inn by Wyndham Norton can enjoy a quiet retreat, with downtown Isom still accessible for a day of sightseeing or city adventures. Lock in an affordable, welcoming stay for your Isom visit—reserve your room now!

  Call (855) 234-7135 to book with an agent.
  19.0 miles from Isom, VA 24228

Starting at

$79.99

per night

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Holiday Inn Express Hotel & Suites Pikeville an IHG Hotel

476 South Mayo Trail Pikeville, KY

With budget-friendly rooms beginning at $149.00, Holiday Inn Express Hotel & Suites Pikeville an IHG Hotel provides pleasant accommodations for travelers to Isom, creating a welcoming environment for rest. Kickstart your day with Holiday Inn Express's signature coffee, a perfect morning pick-me-up available in the lobby.

For a calm stay, Holiday Inn Express Hotel & Suites Pikeville an IHG Hotel offers a peaceful retreat, with the added bonus of downtown Isom being a smooth drive away. Set yourself up for an enjoyable Isom visit with budget-friendly accommodations—book today!

  Call (855) 239-4019 to book with an agent.
  19.5 miles from Isom, VA 24228

Starting at

$149.00

per night

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Hampton Inn Norton Va

1051 Park Ave. Sw Norton, VA

Experience the inviting ambiance of Hampton Inn Norton Va on your visit to Isom, where soft accommodations create a warm stay, with rates starting at $114.99. Keep your workout routine on track in Hampton's fully equipped fitness center, designed to cater to all your fitness needs.

For a peaceful retreat, Hampton Inn Norton Va offers quiet surroundings, with the convenience of downtown Isom still being nearby. Stay in Isom with a hotel that brings comfort and convenience to your doorstep—secure now!

  Call (855) 234-2997 to book with an agent.
  19.9 miles from Isom, VA 24228

Starting at

$114.99

per night

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The Landmark Hotel

190 South Mayo Trail Pikeville, KY

Travelers exploring Isom will find a welcoming retreat at The Landmark Hotel, where inviting rooms provide comfort, with budget-friendly rates starting at $89.00. Relax in rooms that offer a lavish escape with plush bedding, elegant furnishings, and comprehensive in-room technology.

For a relaxing stay, The Landmark Hotel offers quiet surroundings, with downtown Isom still nearby for city exploration and adventure. Relax in Isom with a hotel that turns your trip into a sophisticated getaway—lock in today!

  Call (855) 236-8982 to book with an agent.
  20.0 miles from Isom, VA 24228

Starting at

$89.00

per night

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Hampton Inn Norton VA

1051 Park Ave. SW Norton, VA

For an inviting and comfortable stay near Isom, Hampton Inn Norton VA offers budget-friendly rooms with rates beginning at $129.00, creating a warm space. Join community events at Hampton, like evening socials that offer a relaxed setting for networking and relaxation.

For a relaxing stay, Hampton Inn Norton VA offers quiet surroundings, with downtown Isom still nearby for city exploration and adventure. Choose a hotel that brings comfort and affordability together in Isom—book now!

  Call (855) 234-7135 to book with an agent.
  20.0 miles from Isom, VA 24228

Starting at

$129.00

per night

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Hampton Inn Pikeville

831 Hambley Blvd Pikeville, KY

Guests traveling to Isom will appreciate the secure comfort at Hampton Inn Pikeville, where budget-friendly rooms start at $145.99, creating a warm and inviting space for rest. Start your day energized with in-room coffee and tea facilities at Hampton, allowing you to brew your morning beverage just the way you like it.

Surrounded by peace and quiet, Hampton Inn Pikeville lets you relax while keeping the thrills of Isom within reach. Treat yourself to a comfortable Isom getaway that won't strain your budget—lock in now!

  Call (855) 235-6136 to book with an agent.
  20.3 miles from Isom, VA 24228

Starting at

$145.99

per night

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Comfort Inn & Suites

22006 Riverside Dr Grundy, VA

At Comfort Inn & Suites, travelers bound for Isom can enjoy quiet accommodations with rooms starting at $141.99, creating a clean and comfortable space perfect for rest. Stay fit with Comfort Inn's gym facilities, where you can keep up with your fitness routine while on the road.

Discover a peaceful retreat at Comfort Inn & Suites, where quiet lodgings are paired with easy access to Isom's best attractions. Make Isom travel feel effortless with a cost-effective, welcoming hotel—book now!

  Call (855) 235-0725 to book with an agent.
  20.3 miles from Isom, VA 24228

Starting at

$141.99

per night

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Econo Lodge Inn & Suites

551 Highway 58 E Norton, VA

For a budget-friendly stay near Isom, Econo Lodge Inn & Suites offers relaxed accommodations with rates starting at $64.99, creating a clean and comfortable environment. Enjoy complimentary parking at Econo Lodge, adding another layer of value and convenience to your stay.

Enjoy a tranquil stay at Econo Lodge Inn & Suites, offering a peaceful environment with the excitement of Isom nearby for your enjoyment. Enjoy Isom adventures with a cozy, budget-friendly stay—secure your room today!

  Call (855) 239-5277 to book with an agent.
  20.9 miles from Isom, VA 24228

Starting at

$64.99

per night

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Western Front Hotel

3025 4th Ave. St. Paul, VA

With rooms beginning at $119.00, Western Front Hotel is a practical choice for travelers visiting Isom, creating a delightful and comfortable space ideal for rest. Enjoy a superior stay experience with rooms that provide added amenities and comfort at a budget-friendly price.

Unwind at Western Front Hotel, where a calm atmosphere makes it easy to enjoy Isom whenever you wish. Get ready for a memorable Isom trip with lodging that puts you first—secure now!

  Call (855) 233-0132 to book with an agent.
  21.2 miles from Isom, VA 24228

Starting at

$119.00

per night

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Brookshire Inn & Suites

123 Alexandra Drive Pikeville, KY

At Brookshire Inn & Suites, travelers visiting Isom can enjoy inviting accommodations with rooms starting at $135.00, creating a warm, welcoming environment for rest. Stay in accommodations that cater to your comfort with additional features, ensuring a pleasant and affordable visit.

Find your peaceful escape at Brookshire Inn & Suites, where quiet surroundings and quick access to Isom come together seamlessly. Take the guesswork out of Isom travel with a hotel that delivers on value—lock in today!

  Call (855) 236-8982 to book with an agent.
  22.1 miles from Isom, VA 24228

Starting at

$135.00

per night

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Quality Inn & Suites

4609 Aerial Way Big Stone Gap, VA

With affordable rooms from $98.99, Quality Inn & Suites is ideal for travelers visiting Isom, creating a comfortable and welcoming atmosphere perfect for relaxation. Enjoy freshly brewed coffee in the lobby of Quality Inn, a welcome treat to energize your mornings or afternoons.

Discover a calming atmosphere at Quality Inn & Suites, where you can enjoy peaceful surroundings while keeping Isom easily within reach. Settle into Isom with a hotel that makes your stay memorable and cost-effective—lock in now!

  Call (855) 234-7135 to book with an agent.
  27.8 miles from Isom, VA 24228

Starting at

$98.99

per night

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Super 8 by Wyndham Lebanon

71 Townview Dr Lebanon, VA

With budget-friendly rooms beginning at $62.99, Super 8 by Wyndham Lebanon is ideal for travelers visiting Isom, providing a warm and inviting atmosphere for a restful stay. Welcome warmth and efficiency at Super 8, where every aspect of your stay is designed with your satisfaction in mind.

Discover peace and relaxation at Super 8 by Wyndham Lebanon, where a serene retreat is balanced with close proximity to Isom. Make your Isom experience enjoyable without the high cost—reserve today!

  Call (855) 234-7135 to book with an agent.
  29.8 miles from Isom, VA 24228

Starting at

$62.99

per night

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Holiday Inn Express & Suites Lebanon an IHG Hotel

228 Regional Park Road Lebanon, VA

With rates beginning at $139.00, Holiday Inn Express & Suites Lebanon an IHG Hotel is a smart choice for travelers to Isom, creating a serene space perfect for rest and relaxation. Experience the convenience of Holiday Inn Express's mobile app, offering digital room keys and streamlined service requests.

Unwind in style at Holiday Inn Express & Suites Lebanon an IHG Hotel, where comfort and accessibility to Isom come together to create a refreshing stay. Enjoy peace of mind on your Isom trip with accommodations designed for relaxation—book today!

  Call (855) 234-2997 to book with an agent.
  30.0 miles from Isom, VA 24228

Starting at

$139.00

per night

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Super 8 by Wyndham Prestonsburg

80 Shoppers Path Prestonsburg, KY

Guests traveling to Isom can unwind at Super 8 by Wyndham Prestonsburg, where budget-friendly rooms begin at $68.99, creating a welcoming and comfortable atmosphere. Receive attentive and caring service at Super 8, where the staff are committed to making your stay as comfortable as possible.

Perfect for quiet nights and adventurous days, Super 8 by Wyndham Prestonsburg is your gateway to relaxation and Isom's lively streets. Experience Isom with comfort and budget-savvy rates—lock in your stay today!

  Call (855) 239-5277 to book with an agent.
  36.8 miles from Isom, VA 24228

Starting at

$68.99

per night

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Comfort Suites Prestonsburg West

51 Hal Rogers Dr Prestonsburg, KY

Guests bound for Isom will appreciate the inviting accommodations at Comfort Suites Prestonsburg West, where tucked away rooms start at $119.99, creating a welcoming space for rest. Embrace the ample space and comfort offered by Comfort Suites, where every suite feels like a second home.

At Comfort Suites Prestonsburg West, you’ll find a restful atmosphere that keeps the excitement of Isom within easy reach. Step into Isom with a hotel that makes your visit enjoyable and cost-effective—book now!

  Call (855) 235-0725 to book with an agent.
  37.2 miles from Isom, VA 24228

Starting at

$119.99

per night

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Quality Inn & Suites

85 Hal Rogers Drive Prestonsburg, KY

For a harmonious, budget-friendly stay, Quality Inn & Suites offers inviting rooms with rates from $75.99, creating a clean and comfortable atmosphere near Isom. Experience swift and smooth check-ins and check-outs at Quality Inn, designed for your convenience.

At Quality Inn & Suites, spacious accommodations and a peaceful setting make it a perfect choice for guests visiting Isom. Make your Isom journey relaxing and budget-smart with well-appointed lodging—secure today!

  Call (855) 233-0132 to book with an agent.
  37.2 miles from Isom, VA 24228

Starting at

$75.99

per night

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Travel Inn Duffield

382 Duff Patt Hwy Duffield, VA

For a restful and affordable stay, Travel Inn Duffield offers inviting rooms with rates starting at $69.99, creating a enchanting and comfortable space ideal for travelers bound for Isom. Experience dependable comfort in rooms that offer standard amenities, ensuring a pleasant and budget-conscious stay.

Experience a refreshing stay at Travel Inn Duffield, with both spacious accommodations and convenient access to Isom. Stay affordably and enjoy Isom with added value and ease—reserve now!

  Call (855) 239-4019 to book with an agent.
  37.6 miles from Isom, VA 24228

Starting at

$69.99

per night

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Super 8 by Wyndham Richlands / Claypool Hill Area

12367 Gov G C Peery Hwy Pounding Mill, VA

Guests traveling to Isom will find Super 8 by Wyndham Richlands / Claypool Hill Area a safe and budget-friendly option, with rooms starting at $72.99, creating a warm and welcoming environment for relaxation. Count on Super 8's dedicated staff to ensure your stay is enjoyable, with a friendly and helpful approach to guest service.

Find your perfect getaway at Super 8 by Wyndham Richlands / Claypool Hill Area, where relaxation meets the convenience of having Isom nearby. Stay affordably and comfortably on your Isom adventure—reserve today!

  Call (855) 239-4019 to book with an agent.
  40.3 miles from Isom, VA 24228

Starting at

$72.99

per night

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Fox Run Resort

1274 Left Fork Bens Crk Wharncliffe, WV

For an affordable stay near Isom, Fox Run Resort offers alluring accommodations with rooms beginning at $150.99, creating a warm and welcoming atmosphere perfect for rest. Experience reliable comfort in rooms that offer standard amenities, ensuring a pleasant and budget-conscious stay.

At Fox Run Resort, you'll find a peaceful retreat with the added benefit of being close to Isom for exploration. Stay comfortably and save on your Isom adventure—lock in your room today!

  Call (855) 239-4019 to book with an agent.
  40.4 miles from Isom, VA 24228

Starting at

$150.99

per night

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Holiday Inn Express & Suites Claypool Hill (Richlands Area) an IHG Hotel

180 Clay Dr Pounding Mill, VA

With rates beginning at $159.00, Holiday Inn Express & Suites Claypool Hill (Richlands Area) an IHG Hotel provides budget-conscious accommodations for travelers visiting Isom, creating a serene space ideal for rest. Experience the convenience of Holiday Inn Express's pre-arrival requests, letting you customize your room settings before you arrive.

Step into comfort at Holiday Inn Express & Suites Claypool Hill (Richlands Area) an IHG Hotel, where guests can relax and still reach the cultural and entertainment hotspots of Isom. Find your ideal Isom hotel with amenities that make your visit extra special—lock in today!

  Call (855) 233-7850 to book with an agent.
  40.6 miles from Isom, VA 24228

Starting at

$159.00

per night

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