The best deals on hotels when visiting Issaquena in Mississippi.

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Top 24 Hotels In Issaquena, Mississippi 39054

Days Inn by Wyndham Tallulah

143 Highway 65 South Tallulah, LA

At just $132.99, Days Inn by Wyndham Tallulah near Issaquena provides neat, well-maintained accommodations for budget-conscious travelers seeking a relaxing and affordable stay. Relax in our well-appointed lobbies, perfect for casual meetings or simply enjoying a quiet moment with a complimentary newspaper.

Relax in the calm environment of Days Inn by Wyndham Tallulah, knowing that the many attractions of Issaquena are never far away. Choose a cost-effective Issaquena stay today and keep more in your travel fund!

  Call (855) 234-5074 to book with an agent.
  23.9 miles from Issaquena, Middle School 39054

Starting at

$132.99

per night

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Anchuca Historic Mansion & Inn

1010 1st East St. Vicksburg, MS

Relax in the inviting surroundings of Anchuca Historic Mansion & Inn as you journey to Issaquena, where quality rooms offer warmth and comfort, with room rates beginning at $240.99. Experience a stay that goes beyond the ordinary, with rooms equipped for comfort and convenience in a welcoming environment.

Escape to the peace and quiet of Anchuca Historic Mansion & Inn, where guests can unwind and still explore Issaquena whenever they choose. Take your Issaquena experience to new heights with thoughtfully appointed lodging—reserve now!

  Call (855) 234-5074 to book with an agent.
  29.4 miles from Issaquena, Middle School 39054

Starting at

$240.99

per night

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Halpino

1001 Locust St Vicksburg, MS

With rooms from $90.99, Halpino provides snug, budget-conscious comfort for travelers bound for Issaquena, creating a clean and welcoming environment. Experience lodging that understands the basics, with rooms that offer essential comforts and a welcoming environment.

Experience a refreshing stay at Halpino, with both spacious accommodations and convenient access to Issaquena. Stay comfortably while keeping expenses low on your Issaquena adventure—reserve today!

  Call (855) 233-0132 to book with an agent.
  29.6 miles from Issaquena, Middle School 39054

Starting at

$90.99

per night

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Mulberry a Wyndham Hotel

1310 Mulberry St Vicksburg, MS

Find a peaceful escape at Mulberry a Wyndham Hotel near Issaquena, where heartwarming rooms create a welcoming stay, with affordable rates starting at $127.99 per night. Experience a harmonious blend of comfort and functionality in our rooms, designed to enhance both leisure and business trips.

Enjoy a quiet stay at Mulberry a Wyndham Hotel, where guests can recharge and still visit Issaquena's lively attractions just a short drive away. Step into a world of comfort and convenience on your Issaquena adventure—book now!

  Call (855) 235-6136 to book with an agent.
  29.7 miles from Issaquena, Middle School 39054

Starting at

$127.99

per night

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Studio 6 Vicksburg MS Downtown

1313 Walnut Street Vicksburg, MS

At Studio 6 Vicksburg MS Downtown, travelers to Issaquena can find budget-conscious comfort with rooms beginning at $69.99, creating a appealing, comfortable environment for guests. Relax with the knowledge that Studio 6 places a high priority on cleanliness, with rigorous standards for every suite.

At Studio 6 Vicksburg MS Downtown, guests can unwind in spacious rooms while keeping the dynamic streets of Issaquena within reach. Stay comfortably and on budget while visiting Issaquena—lock in your stay today!

  Call (855) 233-7850 to book with an agent.
  29.7 miles from Issaquena, Middle School 39054

Starting at

$69.99

per night

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Home2 Suites by Hilton Vicksburg MS

40 Maxwell Dr. Vicksburg, MS

Enjoy a peaceful stay at Home2 Suites by Hilton Vicksburg MS as you visit Issaquena, where delightful accommodations create a welcoming ambiance, with nightly rates starting at $135.99. Enjoy peace of mind with state-of-the-art security systems, including surveillance cameras and secure key card access to all areas.

At Home2 Suites by Hilton Vicksburg MS, guests can recharge in peaceful surroundings and still have the option to explore the sights of Issaquena. Discover how relaxing Issaquena can be with a hotel that ensures your happiness—secure now!

  Call (855) 233-7850 to book with an agent.
  30.3 miles from Issaquena, Middle School 39054

Starting at

$135.99

per night

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The Inn at Cedar Grove

2200 Oak St Vicksburg, MS

Embrace quality and warmth at The Inn at Cedar Grove on your trip to Issaquena, where inviting rooms provide relaxation, with rates from an affordable $141.99. Find a luxurious escape in rooms that provide comfort and elegance, equipped with all the amenities for a perfect stay.

Unwind in the serene setting of The Inn at Cedar Grove, while knowing Issaquena's lively streets are never too far away. Experience a Issaquena getaway that’s designed to provide pure relaxation—lock in your room today!

  Call (855) 235-0725 to book with an agent.
  30.3 miles from Issaquena, Middle School 39054

Starting at

$141.99

per night

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Quality Inn Vicksburg

3975 South Frontage Rd Vicksburg, MS

Guests headed to Issaquena will appreciate the restorative comfort at Quality Inn Vicksburg, where rooms start at $69.99, creating a clean, welcoming environment for relaxation. Travel without leaving your pets behind, thanks to Quality Inn's friendly pet policy, welcoming your furry companions.

Rest comfortably at Quality Inn Vicksburg, enjoying the balance between a calm retreat and easy access to Issaquena's highlights. Find the best way to enjoy Issaquena with accommodations that fit your needs—reserve now!

  Call (855) 234-7135 to book with an agent.
  30.4 miles from Issaquena, Middle School 39054

Starting at

$69.99

per night

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Hampton Inn & Suites Vicksburg

3330 Clay St Vicksburg, MS

With budget-friendly rooms starting at $122.99, Hampton Inn & Suites Vicksburg is ideal for guests bound for Issaquena, creating a clean and inviting space perfect for relaxation. Savor the convenience and taste of Hampton’s vending machines, stocked with a variety of snacks and beverages for quick refreshment.

Found just beyond the city, Hampton Inn & Suites Vicksburg offers a peaceful retreat that’s never too far from Issaquena's lively attractions. Relax and enjoy Issaquena with a welcoming hotel that fits your budget perfectly—secure today!

  Call (855) 239-5277 to book with an agent.
  30.4 miles from Issaquena, Middle School 39054

Starting at

$122.99

per night

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Courtyard Marriott Vicksburg

1 Underwood Dr Vicksburg, MS

Courtyard Marriott Vicksburg is a comforting option for travelers visiting Issaquena, with easygoing rooms that create a relaxing atmosphere, with rates beginning at an inviting $154.99 per night. Relax with the personalized service of Courtyard's guest experience managers, dedicated to making your stay as comfortable and enjoyable as possible.

Discover the tranquility of Courtyard Marriott Vicksburg, perfectly nestled for those who want to balance calm surroundings with city exploration. Relax in Issaquena with a hotel that provides everything you need for a seamless stay—lock in today!

  Call (855) 236-8982 to book with an agent.
  30.5 miles from Issaquena, Middle School 39054

Starting at

$154.99

per night

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Holiday Inn Express & Suites Vicksburg an IHG Hotel

4330 South Frontage Rd Vicksburg, MS

With rates beginning at $159.00, Holiday Inn Express & Suites Vicksburg an IHG Hotel is ideal for guests visiting Issaquena, offering quiet accommodations in a welcoming, clean environment. Indulge in the added convenience of Holiday Inn Express's express checkout service, allowing for a swift and easy departure process.

Rest comfortably at Holiday Inn Express & Suites Vicksburg an IHG Hotel, enjoying the balance between a calm retreat and easy access to Issaquena's highlights. Get the rest and comfort you deserve while exploring Issaquena—secure your hotel room now!

  Call (855) 236-8982 to book with an agent.
  30.5 miles from Issaquena, Middle School 39054

Starting at

$159.00

per night

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Comfort Suites Vicksburg

100 Berryman Rd Vicksburg, MS

Guests traveling to Issaquena will find inviting accommodations at Comfort Suites Vicksburg, with rooms starting at $124.99, creating a clean and welcoming environment ideal for relaxation. Experience Comfort Suites' allergy-friendly rooms, specifically designed to reduce allergens for sensitive guests.

Guests at Comfort Suites Vicksburg can experience the charm of a peaceful retreat while remaining close enough to explore Issaquena. Uncover the charm of Issaquena with a hotel that offers top-notch comfort for less—book today!

  Call (855) 235-6136 to book with an agent.
  30.5 miles from Issaquena, Middle School 39054

Starting at

$124.99

per night

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La Quinta Inn & Suites by Wyndham Vicksburg

4160 South Frontage Rd Vicksburg, MS

For an affordable stay near Issaquena, La Quinta Inn & Suites by Wyndham Vicksburg offers inviting rooms with rates starting at $88.99, creating a clean, comfortable atmosphere perfect for relaxation. Benefit from the peace of mind provided by La Quinta’s comprehensive fire safety and emergency preparedness systems.

Discover the tranquility of La Quinta Inn & Suites by Wyndham Vicksburg, where restful accommodations are perfectly balanced with proximity to Issaquena. Stay effortlessly in Issaquena with a hotel that ensures your stay is worry-free—reserve now!

  Call (855) 234-7135 to book with an agent.
  30.6 miles from Issaquena, Middle School 39054

Starting at

$88.99

per night

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Super 8 by Wyndham Tallulah LA

1604 NE Highway 65 S Tallulah, LA

For budget-conscious guests visiting Issaquena, Super 8 by Wyndham Tallulah LA offers charming rooms with rates starting at $122.99, creating a warm and welcoming environment perfect for relaxation. Stay in comfort with Super 8's air-conditioned rooms, a welcome feature during warmer months or in hotter climates.

Discover the ideal balance of serenity and access at Super 8 by Wyndham Tallulah LA, situated just a drive away from the action in Issaquena. Lock in enhanced comfort for your Issaquena adventure—reserve your hotel now!

  Call (855) 234-5074 to book with an agent.
  30.6 miles from Issaquena, Middle School 39054

Starting at

$122.99

per night

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Best Western Vicksburg

2445 North Frontage Rd Vicksburg, MS

At Best Western Vicksburg, travelers to Issaquena will find peaceful, budget-friendly accommodations with rates from $98.99, creating a welcoming environment perfect for rest. Explore the benefits of Best Western’s partnership programs, offering discounts and perks with airlines, car rentals, and more.

Offering a perfect retreat from the hustle and bustle, Best Western Vicksburg is an ideal base for exploring Issaquena. Discover Issaquena with a hotel that offers unbeatable comfort at a great value—lock in now!

  Call (855) 235-0725 to book with an agent.
  31.3 miles from Issaquena, Middle School 39054

Starting at

$98.99

per night

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Asam Hotel

4041 Washington St Vicksburg, MS

With budget-conscious rooms starting at $67.99, Asam Hotel provides affordable comfort for travelers bound for Issaquena, creating a delightful and relaxing atmosphere. Enjoy the convenience of rooms equipped with necessary comforts, providing a solid foundation for a budget-friendly journey.

Discover relaxation at Asam Hotel, where quiet comfort meets the convenience of being close to Issaquena's vibrant offerings. Book a practical, inviting hotel for your Issaquena adventure and save—secure now!

  Call (855) 233-0132 to book with an agent.
  31.7 miles from Issaquena, Middle School 39054

Starting at

$67.99

per night

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Travel Inn

1675 North Frontage Road Vicksburg, MS

Travel Inn offers budget-friendly comfort for travelers headed to Issaquena, with rooms starting at $76.50, creating a clean, inviting environment perfect for unwinding. Experience the convenience of rooms designed for the practical traveler, offering basic amenities and a comfortable environment.

Take time to relax at Travel Inn, where a calm setting is complemented by the convenience of being near Issaquena. Enjoy more of Issaquena for less with budget-friendly, inviting hotel rooms—book now!

  Call (855) 234-5074 to book with an agent.
  31.7 miles from Issaquena, Middle School 39054

Starting at

$76.50

per night

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Holiday Inn Vicksburg an IHG Hotel

115 Cypress Centre Blvd. Vicksburg, MS

Find a relaxing retreat at Holiday Inn Vicksburg an IHG Hotel near Issaquena, where comforting rooms create a welcoming stay, with inviting rates starting from a friendly $140.99. Experience the charm of Holiday Inn's lobby coffee shops, where you can enjoy your favorite brew or grab a quick bite.

Step into a quiet retreat at Holiday Inn Vicksburg an IHG Hotel, offering serene surroundings just a short drive from the buzz of Issaquena. Take advantage of well-appointed lodging that enhances your Issaquena adventure—reserve now!

  Call (855) 239-4019 to book with an agent.
  31.8 miles from Issaquena, Middle School 39054

Starting at

$140.99

per night

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Econo Lodge Yazoo City

1600 Jerry Clower Blvd Yazoo City, MS

Guests traveling to Issaquena will appreciate the budget-friendly comfort at Econo Lodge Yazoo City, where sheltered rooms start at $75.99, creating a clean, inviting space. Unwind in the simply designed yet comfortable rooms at Econo Lodge, tailored for a stress-free and convenient stay.

Discover the perfect escape at Econo Lodge Yazoo City, where the peaceful ambiance is matched by the convenience of Issaquena's nearby attractions. Make your Issaquena visit both cozy and cost-effective—secure your hotel room now!

  Call (855) 235-6136 to book with an agent.
  31.9 miles from Issaquena, Middle School 39054

Starting at

$75.99

per night

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Days Inn by Wyndham Yazoo City

1801 Jerry Clower Blvd Yazoo City, MS

With rooms starting at $104.99, Days Inn by Wyndham Yazoo City is a comfortable choice for guests visiting Issaquena, creating a warm and inviting space ideal for a peaceful stay. Enjoy family-oriented services, including spacious rooms and entertainment options that cater to guests of all ages.

Enjoy a refreshing stay at Days Inn by Wyndham Yazoo City, where the comfort of spacious rooms is matched by easy access to Issaquena. Make your Issaquena visit both cozy and cost-effective—secure your hotel room now!

  Call (855) 234-2997 to book with an agent.
  31.9 miles from Issaquena, Middle School 39054

Starting at

$104.99

per night

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Hampton Inn Yazoo City

2161 Grand Ave Yazoo City, MS

Guests headed to Issaquena will find budget-friendly comfort at Hampton Inn Yazoo City, where easygoing rooms begin at $128.99, creating a welcoming atmosphere perfect for relaxation. Make use of Hampton’s luggage storage services, offering a secure place to store your bags pre-check-in or post-check-out.

Discover your peaceful sanctuary at Hampton Inn Yazoo City, where the calm of your stay is enhanced by the proximity to Issaquena's top spots. Settle into Issaquena with a hotel that prioritizes your relaxation and budget—secure now!

  Call (855) 236-8982 to book with an agent.
  32.0 miles from Issaquena, Middle School 39054

Starting at

$128.99

per night

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Rodeway Inn Vicksburg

2 Pemberton Pl Vicksburg, MS

For a welcoming stay near Issaquena, Rodeway Inn Vicksburg offers snug accommodations with rates from $59.99, creating a clean and comfortable environment perfect for rest. Enjoy reliable comfort in rooms that provide everything you need for a worry-free visit at an economical price.

Stay at Rodeway Inn Vicksburg to enjoy a blend of relaxation and excitement, with Issaquena never far from your tranquil retreat. Stay comfortably and affordably while discovering Issaquena—lock in your hotel room today!

  Call (855) 236-8982 to book with an agent.
  32.0 miles from Issaquena, Middle School 39054

Starting at

$59.99

per night

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Candlewood Suites Vicksburg an IHG Hotel

1296 South Frontage Road Vicksburg, MS

For an affordable stay, Candlewood Suites Vicksburg an IHG Hotel offers budget-conscious accommodations with rooms beginning at $134.00, creating a clean, welcoming space near Issaquena. Competitive rates at Candlewood Suites ensure you receive great value for spacious and well-appointed accommodations.

At Candlewood Suites Vicksburg an IHG Hotel, you can experience the charm of a quiet stay with easy access to Issaquena's most popular attractions. Relax and explore Issaquena with a hotel that keeps your expenses low and spirits high—reserve now!

  Call (855) 234-5074 to book with an agent.
  32.0 miles from Issaquena, Middle School 39054

Starting at

$134.00

per night

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Best Western Gateway Inn

286 Wyeth Dr Yazoo City, MS

Guests bound for Issaquena will find enchanting accommodations at Best Western Gateway Inn, where rooms start at $119.99, creating a warm and inviting environment ideal for relaxation. Enjoy the taste of fresh, locally sourced produce at Best Western’s on-site restaurants, committed to sustainable dining.

At Best Western Gateway Inn, guests can enjoy the best of both worlds—peaceful surroundings with the vibrant energy of Issaquena never far away. Enjoy well-rounded amenities and budget-friendly rates for your Issaquena trip—reserve now!

  Call (855) 234-2997 to book with an agent.
  32.0 miles from Issaquena, Middle School 39054

Starting at

$119.99

per night

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