The best deals on hotels when visiting Jefferson in South Carolina.

From game day to getaway, save even more on every hotel stay.

Save up to 70% when booking as a group. Select 9+ rooms to get started.

Top 24 Hotels In Jefferson, South Carolina 29718

Days Inn by Wyndham Monroe NC

1608 East Roosevelt Blvd. Monroe, NC

Guests headed to Jefferson will find affordable comfort at Days Inn by Wyndham Monroe NC, with restorative rooms starting at $73.99, creating a welcoming and comfortable space for rest. Count on attentive and caring service from the Days Inn team, who are dedicated to making your stay as enjoyable as possible.

Find your peaceful escape at Days Inn by Wyndham Monroe NC, offering quiet surroundings and easy access to the lively offerings of Jefferson. Make the most of your Jefferson trip with a budget-wise stay—book today!

  Call (855) 239-5277 to book with an agent.
  23.3 miles from Jefferson, SC 29718

Starting at

$73.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Monroe

350 Venus St Monroe, NC

For travelers headed to Jefferson, Super 8 by Wyndham Monroe offers soft, budget-friendly accommodations with rooms starting at $69.00, creating a warm, inviting space. Rely on Super 8 for a consistent and dependable lodging experience, no matter where your travels take you.

Guests at Super 8 by Wyndham Monroe will appreciate the quiet surroundings and convenient access to Jefferson's most popular spots. Plan your Jefferson getaway with ease and value-driven comfort—book today!

  Call (855) 239-5277 to book with an agent.
  23.7 miles from Jefferson, SC 29718

Starting at

$69.00

per night

Read Reviews View Amenities View All Rooms

Quality Inn Lancaster

114 Commerce Blvd Lancaster, SC

Guests visiting Jefferson can relax in soft comfort at Quality Inn Lancaster, where budget-friendly rooms start at $95.99, creating a warm, welcoming space. Explore the area with Quality Inn's bike rental service, a fun and eco-friendly way to tour the local sights.

Immerse yourself in the comfort of Quality Inn Lancaster, while Jefferson remains easily accessible for day trips or city explorations. Plan your Jefferson getaway with accommodations that make your stay seamless—reserve now!

  Call (855) 234-2997 to book with an agent.
  24.0 miles from Jefferson, SC 29718

Starting at

$95.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Lancaster

1201 Highway 9 Byp W Lancaster, SC

For a comforting stay near Jefferson, Super 8 by Wyndham Lancaster offers inviting accommodations with rooms beginning at $83.99, creating a warm and welcoming environment ideal for rest. Breathe easy in Super 8’s smoke-free rooms, promoting a clean and healthy environment for all guests.

At Super 8 by Wyndham Lancaster, guests can experience the balance of a quiet stay with the convenience of being close to Jefferson's attractions. Stay affordably and comfortably while visiting Jefferson—book your room now!

  Call (855) 234-5074 to book with an agent.
  24.1 miles from Jefferson, SC 29718

Starting at

$83.99

per night

Read Reviews View Amenities View All Rooms

Relax Inn Monroe

611 West Roosevelt Blvd Monroe, NC

For a comfortable and budget-friendly stay, Relax Inn Monroe offers delightful rooms with rates from $63.99, creating a welcoming, clean environment near Jefferson. Find a comfortable retreat in our rooms, where basic amenities and attentive service create a value-driven experience.

Stay at Relax Inn Monroe to enjoy a restful atmosphere and keep the fun of Jefferson close at hand for day trips and adventures. Enjoy added comfort and savings on your Jefferson trip—book your hotel stay now!

  Call (855) 234-7135 to book with an agent.
  24.8 miles from Jefferson, SC 29718

Starting at

$63.99

per night

Read Reviews View Amenities View All Rooms

Red Roof Inn & Suites Monroe NC

608 West Roosevelt Blvd. STE E Monroe, NC

With rates starting at $79.00, Red Roof Inn & Suites Monroe NC provides budget-conscious accommodations for guests visiting Jefferson, creating a appealing and inviting space for relaxation. Unwind with Red Roof Inn's expanded cable TV offerings, providing entertainment and relaxation after a day of travel or meetings.

Positioned just beyond the city, Red Roof Inn & Suites Monroe NC offers a peaceful retreat that’s never too far from Jefferson's lively attractions. Book your Jefferson stay and experience comfort without the expense—reserve today!

  Call (855) 236-8982 to book with an agent.
  24.8 miles from Jefferson, SC 29718

Starting at

$79.00

per night

Read Reviews View Amenities View All Rooms

Fairfield Inn by Marriott Hartsville

200 South 4th St Hartsville, SC

At Fairfield Inn by Marriott Hartsville, travelers visiting Jefferson can enjoy inviting comfort with rooms beginning at $169.99, creating a warm and welcoming atmosphere ideal for rest. Indulge in Fairfield’s bakery corner, featuring fresh pastries and breads baked daily on the premises.

Guests will appreciate the calm environment at Fairfield Inn by Marriott Hartsville, where restful lodgings are paired with quick access to Jefferson. Choose a hotel in Jefferson that keeps both your comfort and wallet in mind—reserve now!

  Call (855) 236-8982 to book with an agent.
  26.1 miles from Jefferson, SC 29718

Starting at

$169.99

per night

Read Reviews View Amenities View All Rooms

Hampton Inn & Suites Hartsville

203 East Carolina Ave. Hartsville, SC

With budget-conscious rooms from $170.99, Hampton Inn & Suites Hartsville provides relaxed accommodations for guests bound for Jefferson, creating a clean, comfortable space. Discover local flavors and sights with recommendations from Hampton's friendly staff, always ready to share their favorite local tips.

Escape to Hampton Inn & Suites Hartsville for a peaceful retreat, where guests can unwind and still explore Jefferson with ease. Find peace of mind during your Jefferson adventure with lodging that prioritizes comfort—book today!

  Call (855) 234-5074 to book with an agent.
  26.2 miles from Jefferson, SC 29718

Starting at

$170.99

per night

Read Reviews View Amenities View All Rooms

Quality Inn Cheraw

885 Chesterfield Hwy Cheraw, SC

For a relaxing stay, Quality Inn Cheraw offers intimate rooms with rates starting at $98.99, creating a clean, welcoming space ideal for guests traveling to Jefferson. Stay connected with complimentary high-speed Wi-Fi at Quality Inn, perfect for checking emails or streaming your favorite shows.

At Quality Inn Cheraw, guests are treated to a peaceful environment with the added bonus of being close to the energy of Jefferson. Experience Jefferson in style and on budget with accommodations tailored for you—lock in today!

  Call (855) 235-0725 to book with an agent.
  26.4 miles from Jefferson, SC 29718

Starting at

$98.99

per night

Read Reviews View Amenities View All Rooms

Best Western Inn & Suites Monroe

2316 Hanover Drive Monroe, NC

With budget-friendly rooms starting at $119.99, Best Western Inn & Suites Monroe provides inviting accommodations for travelers to Jefferson, creating a safe environment. Relax in the privacy of Best Western’s adults-only areas, designed for guests looking for a quieter, more mature atmosphere.

Guests seeking tranquility will love Best Western Inn & Suites Monroe, a peaceful retreat that offers quick access to Jefferson for easy exploration. Make every moment in Jefferson memorable with a hotel that fits your budget—reserve today!

  Call (855) 235-0725 to book with an agent.
  26.7 miles from Jefferson, SC 29718

Starting at

$119.99

per night

Read Reviews View Amenities View All Rooms

Quality Inn&Suites Monroe

2351 West Roosevelt Blvd Monroe, NC

For a relaxing stay, Quality Inn&Suites Monroe offers relaxing rooms with rates starting at $75.99, creating a clean, welcoming space ideal for guests traveling to Jefferson. Experience the charm and hospitality of Quality Inn's staff, dedicated to making your stay pleasant and memorable.

Discover the best of both worlds at Quality Inn&Suites Monroe, where spacious rooms provide comfort and Jefferson remains nearby for exploration. Make every moment in Jefferson count with a hotel that offers more for less—reserve your room now!

  Call (855) 234-2997 to book with an agent.
  26.7 miles from Jefferson, SC 29718

Starting at

$75.99

per night

Read Reviews View Amenities View All Rooms

Fairfield Inn & Suites by Marriott Charlotte Monroe

1825 WILLIAMS RD. Monroe, NC

Guests bound for Jefferson will find inviting accommodations at Fairfield Inn & Suites by Marriott Charlotte Monroe, where rooms start at $159.99, creating a warm and inviting environment ideal for relaxation. Engage with local culture and community through Fairfield's thoughtful recommendations on area attractions and dining.

Relax in the calm environment of Fairfield Inn & Suites by Marriott Charlotte Monroe, knowing that the many attractions of Jefferson are never far away. Step into an unforgettable Jefferson adventure with lodging that offers more for less—lock in today!

  Call (855) 234-7135 to book with an agent.
  26.9 miles from Jefferson, SC 29718

Starting at

$159.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express Hotel & Suites Monroe an IHG Hotel

2505 West Roosevelt Boulevard Monroe, NC

At Holiday Inn Express Hotel & Suites Monroe an IHG Hotel, guests bound for Jefferson will find restorative comfort with rooms starting at $147.00, creating a warm, inviting environment perfect for rest. Relax with the convenience of Holiday Inn Express's poolside service, offering refreshments and snacks while you swim or sunbathe.

Get the restful experience you crave at Holiday Inn Express Hotel & Suites Monroe an IHG Hotel, just a short distance from the exciting venues and activities of Jefferson. Enjoy the convenience of a well-located, affordable hotel while visiting Jefferson—book today!

  Call (855) 234-5074 to book with an agent.
  27.0 miles from Jefferson, SC 29718

Starting at

$147.00

per night

Read Reviews View Amenities View All Rooms

Hampton Inn Charlotte / Monroe

2368 Roland Dr Monroe, NC

With rooms starting at $137.99, Hampton Inn Charlotte / Monroe provides budget-conscious accommodations for travelers bound for Jefferson, creating a warm and inviting space. Rest easy on the clean and fresh Hampton beds®, designed to provide a deep, restful sleep with plush duvets and fluffy pillows.

Escape to Hampton Inn Charlotte / Monroe for a refreshing stay, where peaceful surroundings are paired with the convenience of Jefferson's top spots. Stay smart and relaxed in Jefferson with a hotel that checks every box—book today!

  Call (855) 239-4019 to book with an agent.
  27.2 miles from Jefferson, SC 29718

Starting at

$137.99

per night

Read Reviews View Amenities View All Rooms

The Landmark Inn

1301 South 4th Street Hartsville, SC

Guests traveling to Jefferson will find soft accommodations at The Landmark Inn, with rooms starting at $85.00, creating a warm and welcoming atmosphere. Experience a more enjoyable visit with enhanced amenities in rooms designed for comfort and affordability.

Find your sanctuary at The Landmark Inn, a restful escape that’s ideally positioned for visiting Jefferson whenever you choose. Treat yourself to a well-appointed, affordable hotel while exploring Jefferson—reserve today!

  Call (855) 235-6136 to book with an agent.
  27.7 miles from Jefferson, SC 29718

Starting at

$85.00

per night

Read Reviews View Amenities View All Rooms

Econo Lodge Cheraw Market Street

820 Market St Cheraw, SC

With budget-friendly rooms starting at $89.99, Econo Lodge Cheraw Market Street provides practical accommodations for travelers bound for Jefferson, creating a warm and inviting atmosphere. Wake up to complimentary coffee provided by Econo Lodge, a perfect way to start your day refreshed and ready to go.

Discover your serene retreat at Econo Lodge Cheraw Market Street, perfectly situated for guests seeking quiet comfort near Jefferson. Stay relaxed and enjoy budget-friendly lodging for your Jefferson visit—lock in now!

  Call (855) 235-6136 to book with an agent.
  27.9 miles from Jefferson, SC 29718

Starting at

$89.99

per night

Read Reviews View Amenities View All Rooms

Americas Best Value Inn Wadesboro

209 East Caswell St Wadesboro, NC

For travelers headed to Jefferson, Americas Best Value Inn Wadesboro provides inviting accommodations with rooms starting at $76.99, creating a warm and comfortable environment. Join the Value Club loyalty program and enjoy discounts, rewards, and free stays, adding even more value to your travels.

Experience the tranquility of Americas Best Value Inn Wadesboro, where guests can enjoy a restful stay while still being close to the attractions of Jefferson. Stay smart and save on your Jefferson travels with cost-effective accommodations—secure today!

  Call (855) 233-0132 to book with an agent.
  28.1 miles from Jefferson, SC 29718

Starting at

$76.99

per night

Read Reviews View Amenities View All Rooms

Baymont by Wyndham Cheraw

710 Market St Cheraw, SC

With rooms starting at $84.99, Baymont by Wyndham Cheraw provides affordable accommodations for travelers visiting Jefferson, creating a easygoing and comfortable atmosphere. Enjoy the simplicity and value of Baymont by Wyndham, offering comfortable accommodations without unnecessary frills.

Guests at Baymont by Wyndham Cheraw will appreciate the calm surroundings, with Jefferson's vibrant offerings only a short drive away. Stay in Jefferson with a hotel that caters to your needs and budget—secure your room now!

  Call (855) 236-8982 to book with an agent.
  28.1 miles from Jefferson, SC 29718

Starting at

$84.99

per night

Read Reviews View Amenities View All Rooms

Springhill Suites by Marriott Cheraw

201 Front Street Cheraw, SC

Explore a relaxing stay at Springhill Suites by Marriott Cheraw near Jefferson, where inviting rooms provide warmth and quality, with room rates beginning at just $169.99 per night. Benefit from SpringHill Suites' meeting spaces, perfect for small gatherings, presentations, or collaborative work sessions.

At Springhill Suites by Marriott Cheraw, guests can unwind in spacious rooms while keeping the dynamic streets of Jefferson within reach. Discover the ideal way to explore Jefferson with accommodations that meet your needs—secure now!

  Call (855) 239-5277 to book with an agent.
  28.8 miles from Jefferson, SC 29718

Starting at

$169.99

per night

Read Reviews View Amenities View All Rooms

Landsford Inn

5721 Lancaster Highway Fort Lawn, SC

For budget-conscious travelers headed to Jefferson, Landsford Inn offers relaxing rooms with rates from $99.99, creating a clean and welcoming atmosphere. Enjoy a stay that offers basic amenities and straightforward comfort, perfect for travelers on a budget or in transit.

Enjoy a peaceful stay at Landsford Inn, where guests can relax and still visit Jefferson's lively streets whenever they choose. Make your Jefferson trip stress-free and comfortable with a budget-friendly hotel—lock in now!

  Call (855) 235-6136 to book with an agent.
  29.1 miles from Jefferson, SC 29718

Starting at

$99.99

per night

Read Reviews View Amenities View All Rooms

Colony Inn

2020 DeKalb Street Camden, SC

For an affordable and restful stay near Jefferson, Colony Inn offers budget-friendly accommodations with rooms starting at $74.99, creating a welcoming space. Relax in rooms that provide a perfect blend of comfort and convenience, designed to enhance your travel experience without stretching your budget.

Relax at Colony Inn, a peaceful haven where guests can rest in comfort and still visit Jefferson with ease. Enjoy peace of mind and comfort on your Jefferson trip without the high cost—reserve today!

  Call (855) 234-5074 to book with an agent.
  31.1 miles from Jefferson, SC 29718

Starting at

$74.99

per night

Read Reviews View Amenities View All Rooms

Red Roof Inn Bishopville

1135 Sumter Hwy Bishopville, SC

At Red Roof Inn Bishopville, travelers to Jefferson can enjoy charming, affordable rooms with rates starting at $84.99, creating a warm and welcoming space ideal for relaxation. Rest in Red Roof Inn's thoughtfully designed rooms, where comfort and simplicity create the ideal setting for relaxation.

Stay at Red Roof Inn Bishopville for a quiet and restful experience, while keeping the lively streets of Jefferson close for your adventures. Enjoy Jefferson adventures in comfort without breaking the bank—secure your stay today!

  Call (855) 233-7850 to book with an agent.
  31.3 miles from Jefferson, SC 29718

Starting at

$84.99

per night

Read Reviews View Amenities View All Rooms

Hampton Inn Camden

122 Wall Street Camden, SC

With budget-friendly rooms from $180.99, Hampton Inn Camden provides inviting comfort for travelers visiting Jefferson, creating a warm, welcoming space. Enjoy the practicality of Hampton's on-site parking options, accommodating guests who are traveling with their own vehicles.

At Hampton Inn Camden, you’ll find the balance between relaxation and proximity to Jefferson, making it an ideal base for exploration. Plan your Jefferson getaway with a hotel that knows how to make you feel at home—reserve today!

  Call (855) 235-0725 to book with an agent.
  31.7 miles from Jefferson, SC 29718

Starting at

$180.99

per night

Read Reviews View Amenities View All Rooms

Comfort Inn & Suites

220 Wall St Camden, SC

At Comfort Inn & Suites, guests bound for Jefferson will find pleasant comfort with rooms starting at $150.99, creating a warm, inviting environment perfect for rest. Appreciate the security of Comfort Inn's properties, offering a safe and secure environment for all guests.

Step away from the noise and recharge at Comfort Inn & Suites, where a calm atmosphere is paired with easy access to Jefferson. Make the most of your Jefferson travels with practical, inviting hotel options—lock in now!

  Call (855) 234-5074 to book with an agent.
  32.0 miles from Jefferson, SC 29718

Starting at

$150.99

per night

Read Reviews View Amenities View All Rooms