The best deals on hotels when visiting Lake City in Florida.

From game day to getaway, save even more on every hotel stay.

Save up to 70% when booking as a group. Select 9+ rooms to get started.

Top 24 Hotels In Lake City, Florida 32055

Days Inn by Wyndham Lake City I-75

3144 West US Highway 90 Lake City, FL

With rates starting at $101.92, Days Inn by Wyndham Lake City I-75 provides inviting comfort for travelers visiting Lake City, creating a clean, delightful space ideal for relaxation. Appreciate the vibrant yet soothing interior design of Days Inn, creating a welcoming atmosphere for relaxation and rejuvenation.

At Days Inn by Wyndham Lake City I-75, a quick drive brings guests into the lively downtown area of Lake City, making it easy to explore the city’s best offerings. Plan your Lake City adventure with comfort and affordability—reserve your hotel today!

  Call (855) 234-2997 to book with an agent.
  2.3 miles from Lake City, FL 32055

Starting at

$101.92

per night

Read Reviews View Amenities View All Rooms

La Quinta Inn & Suite by Wyndham Lake City

165NW CALI DRIVE Lake City, FL

Guests bound for Lake City can enjoy affordable comfort at La Quinta Inn & Suite by Wyndham Lake City, where warm rooms start at $123.99, creating a warm and inviting atmosphere for relaxation. Stay energized with the 24-hour coffee and tea service in La Quinta’s lobby, perfect for night owls or early risers.

With downtown Lake City just a brief drive from La Quinta Inn & Suite by Wyndham Lake City, guests can easily explore the city’s most iconic attractions while staying in a quieter setting. Relax and explore Lake City knowing your accommodations provide excellent value—book today!

  Call (855) 234-7135 to book with an agent.
  2.3 miles from Lake City, FL 32055

Starting at

$123.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn & Suites Lake City an IHG Hotel

213 South Commerce Dr Lake City, FL

Choose Holiday Inn & Suites Lake City an IHG Hotel for a comfortable stay on your trip to Lake City, where relaxing rooms create a peaceful atmosphere, with nightly rates starting at $142.49. Kickstart your day with Holiday Inn’s varied breakfast options, packed with delicious, healthy choices to fuel your adventures.

At Holiday Inn & Suites Lake City an IHG Hotel, a quick drive delivers guests into the heart of downtown Lake City, where the city’s most exciting attractions are always within easy reach. Plan your perfect Lake City getaway with accommodations that make relaxation a priority—secure now!

  Call (855) 233-0132 to book with an agent.
  2.4 miles from Lake City, FL 32055

Starting at

$142.49

per night

Read Reviews View Amenities View All Rooms

Knights Inn Lake City

339 South COMMERCE DR Lake City, FL

With rates beginning at $51.99, Knights Inn Lake City offers welcoming accommodations for guests visiting Lake City, creating a restful and peaceful environment for rest. Enjoy the spacious accommodations at Knights Inn, offering rooms that are larger than typical budget hotel rooms.

Guests staying at Knights Inn Lake City can enjoy easy access to downtown Lake City, where a brief drive takes them to the city’s top destinations. Make the most of your Lake City trip without breaking the bank—book your room now!

  Call (855) 234-2997 to book with an agent.
  2.4 miles from Lake City, FL 32055

Starting at

$51.99

per night

Read Reviews View Amenities View All Rooms

Rodeway Inn Lake City I-75

205 South Commerce Dr Lake City, FL

At Rodeway Inn Lake City I-75, guests visiting Lake City can unwind in inviting accommodations with rooms from $65.99, creating a warm and welcoming space perfect for rest. Stay in a room that balances comfort and practicality, providing dependable amenities for a pleasant visit.

With a brief drive into downtown Lake City, guests at Rodeway Inn Lake City I-75 can easily explore the city’s most iconic spots without staying in the center. Enjoy added perks at a cost-effective rate on your Lake City adventure—secure today!

  Call (855) 235-6136 to book with an agent.
  2.4 miles from Lake City, FL 32055

Starting at

$65.99

per night

Read Reviews View Amenities View All Rooms

Quality Inn Lake City

285 South Commerce Dr Lake City, FL

At Quality Inn Lake City, guests visiting Lake City will enjoy warm-hearted accommodations with rates starting at $93.99, creating a clean and welcoming environment. Trust in Quality Inn's dedication to cleanliness, providing a safe and welcoming environment for every guest.

Quality Inn Lake City is ideally situated for those wanting to visit downtown Lake City, where the city’s top attractions are just a short drive away. Enjoy your Lake City trip with accommodations that add value and comfort—book today!

  Call (855) 234-5074 to book with an agent.
  2.4 miles from Lake City, FL 32055

Starting at

$93.99

per night

Read Reviews View Amenities View All Rooms

Best Western Plus Lake City

350 South Florida Gateway Dr Lake City, FL

With rooms beginning at $113.99, Best Western Plus Lake City provides affordable comfort for travelers to Lake City, creating a warm and welcoming space perfect for relaxation. Relax with a cocktail or a cup of fine coffee in the elegantly designed sitting areas at Best Western Plus.

Guests staying at Best Western Plus Lake City will appreciate the short drive to downtown Lake City, where the city’s top attractions are always within easy reach. Make Lake City travel simple with a hotel that provides convenience and savings—reserve now!

  Call (855) 233-0132 to book with an agent.
  2.6 miles from Lake City, FL 32055

Starting at

$113.99

per night

Read Reviews View Amenities View All Rooms

Home2 Suites by Hilton Lake City

414 Southwest Florida Gateway Boulevard Lake City, FL

Home2 Suites by Hilton Lake City offers travelers to Lake City a delightful option, with quality accommodations designed for relaxation, with rates starting from just $198.09 per night. Engage with Home2 Suites' community boards, offering local insights, guest recommendations, and staff picks of local attractions.

Guests staying at Home2 Suites by Hilton Lake City are never far from the action, with downtown Lake City only a brief drive away for easy exploration. Relax in a Lake City hotel that turns your trip into a delightful experience—lock in today!

  Call (855) 239-5277 to book with an agent.
  2.6 miles from Lake City, FL 32055

Starting at

$198.09

per night

Read Reviews View Amenities View All Rooms

Hampton Inn & Suites Lake City

450 South Florida Gateway Drive Lake City, FL

At Hampton Inn & Suites Lake City, guests bound for Lake City can enjoy affordable accommodations with rooms beginning at $181.99, creating a warm, inviting atmosphere for relaxation. Experience the vibrant energy of Hampton’s redesigned lobbies, serving as dynamic spaces for work, socializing, or simply relaxing.

At Hampton Inn & Suites Lake City, guests can easily access downtown Lake City, where the city’s most vibrant spots are just a short drive away. Treat yourself to a relaxing Lake City getaway without the high cost—secure your room now!

  Call (855) 235-0725 to book with an agent.
  2.6 miles from Lake City, FL 32055

Starting at

$181.99

per night

Read Reviews View Amenities View All Rooms

Econo Lodge Lake City North

178 South Florida Gateway Dr Lake City, FL

For an affordable and restful stay, Econo Lodge Lake City North offers budget-friendly rooms with rates starting at $90.99, creating a clean and comfortable space near Lake City. Rely on Econo Lodge for clean, comfortable rooms and convenient amenities, making it an excellent choice for budget-savvy travelers.

At Econo Lodge Lake City North, a quick drive brings guests into the lively downtown area of Lake City, making it easy to explore the city’s best offerings. Plan your Lake City visit with budget-wise lodging that delivers comfort—book today!

  Call (855) 233-0132 to book with an agent.
  2.7 miles from Lake City, FL 32055

Starting at

$90.99

per night

Read Reviews View Amenities View All Rooms

Fairfield Inn & Suites Lake City

538 South Corporate Dr Lake City, FL

With budget-conscious rooms from $174.99, Fairfield Inn & Suites Lake City provides homely accommodations for guests bound for Lake City, creating a clean, comfortable space. Discover the charm of Fairfield's signature amenities, including Paul Mitchell® bath products for a touch of luxury.

From Fairfield Inn & Suites Lake City, guests can quickly reach downtown Lake City, where the city’s most popular destinations are just minutes away. Take advantage of Lake City travel with lodging that delivers exceptional value—book today!

  Call (855) 234-5074 to book with an agent.
  2.7 miles from Lake City, FL 32055

Starting at

$174.99

per night

Read Reviews View Amenities View All Rooms

Tru by Hilton Lake City

284 North Centurion Court Lake City, FL

At Tru by Hilton Lake City, guests visiting Lake City can enjoy inviting accommodations with rates beginning at $162.99, creating a soft and welcoming space. Experience the fresh, vibrant atmosphere at Tru by Hilton, where smart design and forward-thinking amenities meet to create a memorable stay.

From Tru by Hilton Lake City, guests can quickly reach downtown Lake City, where the city’s best spots are always within easy reach. Rest easy during your Lake City adventure with accommodations that make sense—lock in today!

  Call (855) 234-7135 to book with an agent.
  2.7 miles from Lake City, FL 32055

Starting at

$162.99

per night

Read Reviews View Amenities View All Rooms

Baymont by Wyndham Lake City

3598 West Us Highway 90 Lake City, FL

Guests bound for Lake City can enjoy inviting comfort at Baymont by Wyndham Lake City, where soothing rooms begin at $73.99, creating a warm and welcoming space ideal for relaxation. Relax in Baymont by Wyndham’s hot tubs, available at select locations for a soothing soak after a busy day.

Baymont by Wyndham Lake City offers a perfect location for those wanting to explore Lake City, with the downtown area just a quick drive away for easy access. Experience Lake City in style with a hotel that makes value a priority—lock in today!

  Call (855) 235-0725 to book with an agent.
  2.8 miles from Lake City, FL 32055

Starting at

$73.99

per night

Read Reviews View Amenities View All Rooms

Comfort Suites Lake City

3690 West Us Highway 90 Lake City, FL

Guests traveling to Lake City will find sheltered comfort at Comfort Suites Lake City, with budget-friendly rooms starting at $141.99, creating a warm and inviting space perfect for rest. Enjoy a touch of luxury with Comfort Suites' bathrobe and slipper service, available in select suites for your comfort.

With downtown Lake City only a short drive away, guests at Comfort Suites Lake City can easily explore the city’s best sights while staying in a more peaceful location. Make every day in Lake City a pleasure with a hotel that goes above and beyond—secure now!

  Call (855) 233-7850 to book with an agent.
  2.8 miles from Lake City, FL 32055

Starting at

$141.99

per night

Read Reviews View Amenities View All Rooms

Gateway Inn

3783 West US Highway 90 Lake City, FL

Guests headed to Lake City will appreciate the safe comfort at Gateway Inn, where rooms start at $61.99, creating a clean, welcoming environment for relaxation. Experience practical accommodations, where rooms are designed with the essentials for a comfortable and convenient stay.

Guests staying at Gateway Inn are never far from downtown Lake City, where a quick drive delivers them to the city’s most exciting spots. Plan your Lake City visit with a hotel that keeps you comfortable and on budget—book today!

  Call (855) 235-0725 to book with an agent.
  2.9 miles from Lake City, FL 32055

Starting at

$61.99

per night

Read Reviews View Amenities View All Rooms

Americas Best Value Inn Lake City

3835 West US Highway 90 Lake City, FL

With rates starting at $67.99, Americas Best Value Inn Lake City provides budget-friendly accommodations for guests visiting Lake City, creating a sheltered environment ideal for relaxation. Welcome to Americas Best Value Inn, where great value meets comfort and convenience for travelers on a budget.

At Americas Best Value Inn Lake City, guests are only a short drive from downtown Lake City, where the city’s most iconic spots are easily reachable by car. Enjoy an affordable Lake City experience with extra perks—book your hotel now!

  Call (855) 233-0132 to book with an agent.
  2.9 miles from Lake City, FL 32055

Starting at

$67.99

per night

Read Reviews View Amenities View All Rooms

Days Inn by Wyndham Lake City I-10

3430 North Us Highway 441 Lake City, FL

For budget-conscious guests visiting Lake City, Days Inn by Wyndham Lake City I-10 offers mellifluous accommodations with rates starting at $77.99, creating a warm and welcoming environment. Find peace and comfort in our thoughtfully designed rooms, crafted to enhance relaxation and provide a restful sleep.

With downtown Lake City just a short drive away, guests at Days Inn by Wyndham Lake City I-10 can easily visit the city’s most vibrant spots while staying in a more peaceful location. Plan your Lake City visit with a comfortable and budget-friendly hotel—secure today!

  Call (855) 234-5074 to book with an agent.
  3.3 miles from Lake City, FL 32055

Starting at

$77.99

per night

Read Reviews View Amenities View All Rooms

Quality Inn White Springs Suwanee

3119 County Rd. 136 Live Oak, FL

For a welcoming and budget-friendly stay, Quality Inn White Springs Suwanee offers inviting rooms with rates from $88.40, creating a restorative space ideal for travelers bound for Lake City. Experience the charm and hospitality of Quality Inn's staff, dedicated to making your stay pleasant and memorable.

A calm retreat awaits at Quality Inn White Springs Suwanee, where guests can rest and still reach downtown Lake City with ease. Experience Lake City with ease by booking a hotel that makes value a priority—lock in now!

  Call (855) 236-8982 to book with an agent.
  13.0 miles from Lake City, FL 32055

Starting at

$88.40

per night

Read Reviews View Amenities View All Rooms

Econo Lodge Live Oak

6811 North Us 129 & I 10 Live Oak, FL

With rates starting at $88.00, Econo Lodge Live Oak is a practical choice for travelers visiting Lake City, providing a warm and inviting atmosphere for rest. Settle into the well-kept rooms at Econo Lodge, where cleanliness and comfort are always prioritized for a pleasant stay.

Relax and recharge at Econo Lodge Live Oak, a peaceful spot where you can rest comfortably and still explore Lake City's attractions. Stay relaxed and enjoy more of Lake City with budget-friendly comfort—reserve today!

  Call (855) 234-2997 to book with an agent.
  21.2 miles from Lake City, FL 32055

Starting at

$88.00

per night

Read Reviews View Amenities View All Rooms

Quality Inn & Suites Live Oak I-10 Exit 283

6819 Us Highway 129 Live Oak, FL

Guests headed to Lake City can enjoy affordable comfort at Quality Inn & Suites Live Oak I-10 Exit 283, with rooms starting at $114.99, providing a enchanting space perfect for relaxation. Relax with Quality Inn's evening turndown service, preparing your room each night for a comfortable and restful sleep.

Escape the everyday rush at Quality Inn & Suites Live Oak I-10 Exit 283, where calm surroundings make for a refreshing stay with Lake City just a drive away. Take comfort in knowing your Lake City stay is both cozy and budget-friendly—reserve today!

  Call (855) 233-0132 to book with an agent.
  21.2 miles from Lake City, FL 32055

Starting at

$114.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express & Suites Alachua Gainesville Area an IHG Hotel

16367 North 167TH BLVD Alachua, FL

Travelers to Lake City will find Holiday Inn Express & Suites Alachua Gainesville Area an IHG Hotel a charming retreat, where inviting rooms provide warmth, with nightly rates starting at just $168.99. Stay energized with the 24-hour coffee and tea services available in the lobby at Holiday Inn Express.

Situated outside the urban sprawl, Holiday Inn Express & Suites Alachua Gainesville Area an IHG Hotel offers you peace and quiet with the convenience of Lake City's attractions nearby. Uncover the elegance of Lake City with accommodations that redefine quality—book today!

  Call (855) 233-0132 to book with an agent.
  27.6 miles from Lake City, FL 32055

Starting at

$168.99

per night

Read Reviews View Amenities View All Rooms

Hampton Inn & Suites Alachua I-75

15930 Northwest 163rd Lane Alachua, FL

With budget-friendly rooms starting at $128.99, Hampton Inn & Suites Alachua I-75 provides inviting accommodations for travelers to Lake City, creating a serene environment. Stay energized with Hampton’s fitness facilities, featuring the latest equipment for cardio and strength training.

Escape to Hampton Inn & Suites Alachua I-75 for a relaxing stay, with the added benefit of being close to the exciting venues in Lake City. Find a hotel in Lake City that checks all the boxes for a great stay—book today!

  Call (855) 236-8982 to book with an agent.
  27.8 miles from Lake City, FL 32055

Starting at

$128.99

per night

Read Reviews View Amenities View All Rooms

Americas Best Value Inn Alachua

16100 North US Highway 441 Alachua, FL

At Americas Best Value Inn Alachua, travelers bound for Lake City can relax in inviting accommodations with rooms from $67.99, creating a intimate-feeling and comfortable atmosphere. Experience the value of Americas Best Value Inn's complimentary services, including breakfast and Wi-Fi, enhancing your stay.

Guests at Americas Best Value Inn Alachua will love the restful environment, paired with the ease of reaching Lake City's bustling attractions. Enjoy Lake City with a hotel that makes affordability a top priority—book your room today!

  Call (855) 234-5074 to book with an agent.
  27.9 miles from Lake City, FL 32055

Starting at

$67.99

per night

Read Reviews View Amenities View All Rooms

Royal Inn

16305 North 162nd Lane Alachua, FL

For a restful and affordable stay, Royal Inn offers inviting rooms with rates starting at $78.99, creating a soothing and comfortable space ideal for travelers bound for Lake City. Relax in accommodations that offer a comfortable environment, making your stay both pleasant and affordable.

Find your serene getaway at Royal Inn, where the calm of your stay is paired with the convenience of Lake City's top sights. Book your Lake City visit today and enjoy cost-effective comfort—reserve now!

  Call (855) 235-0725 to book with an agent.
  27.9 miles from Lake City, FL 32055

Starting at

$78.99

per night

Read Reviews View Amenities View All Rooms