The best deals on hotels when visiting Laughlin in South Carolina.

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Top 24 Hotels In Laughlin, South Carolina 29571

Quality Inn Mullins Marion

2693 East Highway 76 Marion, SC

Guests traveling to Laughlin will find inviting accommodations at Quality Inn Mullins Marion, with rooms starting at $82.99, creating a clean and welcoming environment ideal for relaxation. Enjoy a seamless stay with Quality Inn's express services, including fast check-in and check-out to accommodate your schedule.

From Quality Inn Mullins Marion, the drive into downtown Laughlin offers guests the flexibility to explore the city’s highlights while retreating to a more relaxed environment afterward. Enjoy Laughlin adventures with a hotel that’s all about comfort and savings—lock in today!

  Call (855) 235-0725 to book with an agent.
  7.7 miles from Laughlin, SC 29571

Starting at

$82.99

per night

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Holiday Inn Express & Suites Latta an IHG Hotel

2513 CATTLE FARM ROAD Latta, SC

For a comfortable and budget-friendly experience, Holiday Inn Express & Suites Latta an IHG Hotel offers pleasant rooms with rates starting at $189.00, creating a warm environment perfect for rest. Stay hydrated with Holiday Inn Express's complimentary water stations, conveniently located throughout the hotel.

For those seeking tranquility, Holiday Inn Express & Suites Latta an IHG Hotel provides a serene retreat while keeping downtown Laughlin within reach for sightseeing. Stay comfortably and affordably in Laughlin with a hotel that delivers—secure your room now!

  Call (855) 233-7850 to book with an agent.
  10.5 miles from Laughlin, SC 29571

Starting at

$189.00

per night

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Best Western Executive Inn

1534 Highway 38 W Latta, SC

Guests bound for Laughlin can relax in pleasant comfort at Best Western Executive Inn, where rooms start at $111.99, creating a welcoming environment ideal for unwinding. Enjoy the cultural events hosted by Best Western, featuring local music, art, and entertainment to enrich your stay.

Guests at Best Western Executive Inn will find a peaceful escape, while downtown Laughlin remains just a short drive away for all their city adventures. Stay relaxed and on budget while exploring Laughlin with thoughtfully designed lodging—lock in today!

  Call (855) 233-7850 to book with an agent.
  10.9 miles from Laughlin, SC 29571

Starting at

$111.99

per night

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Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 an IHG Hotel

2101 Florence Harllee Blvd Florence, SC

For a relaxing stay near Laughlin, Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 an IHG Hotel offers quiet accommodations with rates beginning at $149.00, creating a warm, inviting atmosphere for rest. Relax in the spacious and airy design of Holiday Inn Express rooms, featuring ample natural light and a layout that maximizes comfort.

A quiet retreat at Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 an IHG Hotel provides rest and relaxation, with downtown Laughlin easily reachable for city adventures. Relax in Laughlin with well-appointed lodging at a wallet-friendly rate—reserve today!

  Call (855) 233-0132 to book with an agent.
  13.7 miles from Laughlin, SC 29571

Starting at

$149.00

per night

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Hyatt Place Florence Downtown

100 East Evans St. Florence Florence, SC

Relax in the comfortable surroundings of Hyatt Place Florence Downtown on your journey to Laughlin, where tucked away rooms offer quality and warmth, with nightly rates beginning at $179.00. Relax in the stylish ambiance of Hyatt Place's Bar, a perfect spot for evening relaxation with innovative cocktails and local craft beers.

Guests at Hyatt Place Florence Downtown will love the quiet atmosphere, with downtown Laughlin remaining nearby for easy access to sightseeing. Settle into Laughlin with a hotel that adds a touch of sophistication to your stay—lock in today!

  Call (855) 233-0132 to book with an agent.
  16.6 miles from Laughlin, SC 29571

Starting at

$179.00

per night

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Hotel Florence Tapestry Collection by Hilton

126 West Evans St Florence, SC

Stay at Hotel Florence Tapestry Collection by Hilton for a relaxing visit to Laughlin, where easygoing accommodations create a warm environment, with nightly rates beginning at an affordable $163.99. Stay active and energized with Tapestry Collection's fitness options, from gyms equipped with the latest gear to customized wellness programs.

Travelers will find a restful escape at Hotel Florence Tapestry Collection by Hilton, where peace meets proximity to downtown Laughlin for adventure. Step into your Laughlin adventure with a hotel that prioritizes comfort and convenience—reserve now!

  Call (855) 233-7850 to book with an agent.
  16.6 miles from Laughlin, SC 29571

Starting at

$163.99

per night

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Economy Inn

1223 Radford Blvd Dillon, SC

Guests traveling to Laughlin will enjoy the inviting accommodations at Economy Inn, with rooms beginning at $115.00, creating a clean and comfortable space for rest. Find comfort in rooms that deliver reliable amenities, ensuring a pleasant stay at a budget-friendly price.

For those seeking both relaxation and city access, Economy Inn provides tranquility while downtown Laughlin remains easily accessible. Book now and enjoy a practical, affordable Laughlin stay—reserve your room today!

  Call (855) 234-7135 to book with an agent.
  17.6 miles from Laughlin, SC 29571

Starting at

$115.00

per night

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Days Inn by Wyndham Dillon

823 Radford Blvd Dillon, SC

Guests bound for Laughlin will appreciate the budget-friendly comfort at Days Inn by Wyndham Dillon, with rooms starting at $77.99, creating a warm and welcoming atmosphere. Appreciate the convenience of on-site dining options, offering meals that cater to a variety of tastes and preferences.

From Days Inn by Wyndham Dillon, guests can enjoy the scenic route into downtown Laughlin, where they can explore the city’s highlights before returning to a serene stay. Stay comfortably and save more on your Laughlin travels—lock in today!

  Call (855) 235-6136 to book with an agent.
  17.8 miles from Laughlin, SC 29571

Starting at

$77.99

per night

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Red Roof Inn Dillon SC

810 Radford Boulevard Dillon, SC

With rooms starting at $83.49, Red Roof Inn Dillon SC is a practical option for guests bound for Laughlin, creating a secure and welcoming environment ideal for relaxation. Experience the brand's dedication to cleanliness, with enhanced cleaning protocols ensuring a safe and comfortable stay.

At Red Roof Inn Dillon SC, guests can relax in serene surroundings, with downtown Laughlin still a convenient drive away for a day of adventure. Enjoy enhanced comfort at a great price for your Laughlin travels—secure now!

  Call (855) 235-0725 to book with an agent.
  17.8 miles from Laughlin, SC 29571

Starting at

$83.49

per night

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Quality Inn & Suites

817 Radford Blvd Dillon, SC

Guests headed to Laughlin will appreciate the calm comfort at Quality Inn & Suites, where rooms start at $94.99, creating a clean, welcoming environment for relaxation. Indulge in quiet evenings with Quality Inn's in-room dining options, combining convenience with the comfort of your own space.

Relax in the tranquil environment at Quality Inn & Suites, with the excitement of downtown Laughlin still nearby for exploration. Plan your Laughlin getaway with a hotel that’s tailored for a perfect stay—secure now!

  Call (855) 239-5277 to book with an agent.
  17.8 miles from Laughlin, SC 29571

Starting at

$94.99

per night

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Baymont Inn & Suites Florence by Wyndham

1826 West Lucas Street Florence, SC

For budget-savvy travelers, Baymont Inn & Suites Florence by Wyndham offers inviting comfort with rates beginning at $43.99, creating a warm and inviting atmosphere perfect for relaxation. Savor a relaxing evening in Baymont by Wyndham’s comfortable guest rooms, equipped with premium cable TV and plush bedding.

Guests staying at Baymont Inn & Suites Florence by Wyndham can enjoy a quiet retreat, with downtown Laughlin just a short drive away for sightseeing or city adventures. Unlock the comfort you deserve on your Laughlin trip with affordable lodging—reserve now!

  Call (855) 233-7850 to book with an agent.
  18.3 miles from Laughlin, SC 29571

Starting at

$43.99

per night

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Best Western Inn

1808 West Lucas Street Florence, SC

With rates from $79.99, Best Western Inn is ideal for travelers bound for Laughlin, providing enveloping, budget-friendly accommodations perfect for relaxation. Stay energized with Best Western’s fitness programs, including guided runs and group exercise classes.

Relax at Best Western Inn, where peaceful surroundings create a restful stay, while downtown Laughlin remains a quick drive away for sightseeing. Find the perfect Laughlin escape with accommodations that don’t break the bank—lock in today!

  Call (855) 233-7850 to book with an agent.
  18.4 miles from Laughlin, SC 29571

Starting at

$79.99

per night

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Super 8 by Wyndham Florence

1832 1 / 2 Lucas St. I95 Exit 164 Florence, SC

With budget-friendly rooms starting at $68.99, Super 8 by Wyndham Florence is a convenient option for travelers to Laughlin, creating a warm-hearted and inviting space perfect for rest. Enjoy great value without compromise at Super 8, offering budget-friendly rates alongside comfortable and clean accommodations.

Experience a serene retreat at Super 8 by Wyndham Florence, where quiet surroundings offer relaxation and downtown Laughlin is just a drive away. Stay relaxed and enjoy added comfort on your Laughlin trip—book your room today!

  Call (855) 234-5074 to book with an agent.
  18.4 miles from Laughlin, SC 29571

Starting at

$68.99

per night

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Clarion Inn & Suites

1819 West Lucas Street Florence, SC

With budget-friendly rooms starting at $47.99, Clarion Inn & Suites provides inviting accommodations for travelers to Laughlin, creating a restful environment. Appreciate the attentive, friendly service from the staff at Clarion Inn, dedicated to making your stay as enjoyable as possible.

At Clarion Inn & Suites, guests can experience peaceful surroundings while having downtown Laughlin within easy driving distance. Take the guesswork out of Laughlin travel with a hotel that delivers on value—lock in today!

  Call (855) 235-0725 to book with an agent.
  18.4 miles from Laughlin, SC 29571

Starting at

$47.99

per night

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MainStay Suites

1819 West Lucas St. Building B Florence, SC

For budget-conscious travelers to Laughlin, MainStay Suites offers charming accommodations with rates from $56.99, creating a clean and comfortable space. Unwind in MainStay Suites’ inviting public spaces, designed for relaxation and social interaction among guests.

At MainStay Suites, guests can unwind in a calm setting, while downtown Laughlin remains easily accessible for sightseeing or city activities. Find the perfect base for your Laughlin adventure with lodging that fits your budget—secure now!

  Call (855) 235-0725 to book with an agent.
  18.4 miles from Laughlin, SC 29571

Starting at

$56.99

per night

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Econo Lodge

1916 West Lucas St Florence, SC

For an affordable and restful stay, Econo Lodge offers inviting accommodations with rooms starting at $56.99, creating a warm, welcoming space ideal for relaxation. Settle into the well-kept rooms at Econo Lodge, where cleanliness and comfort are always prioritized for a pleasant stay.

Unwind in the serene surroundings of Econo Lodge, where guests can enjoy rest while downtown Laughlin is still within reach. Stay comfortably and keep your budget intact while visiting Laughlin—book your room now!

  Call (855) 239-5277 to book with an agent.
  18.6 miles from Laughlin, SC 29571

Starting at

$56.99

per night

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Suburban Studios Florence I-95

1914 West Lucas St Florence, SC

Guests bound for Laughlin will find budget-conscious comfort at Suburban Studios Florence I-95, where tucked away rooms start at $56.99, creating a warm and welcoming environment. Relax in accommodations that provide a solid foundation for your travel needs, offering comfort and value without the frills.

For those seeking quiet, Suburban Studios Florence I-95 offers a serene retreat while keeping downtown Laughlin easily accessible for city exploration. Make your Laughlin experience enjoyable without the high cost—reserve today!

  Call (855) 235-0725 to book with an agent.
  18.6 miles from Laughlin, SC 29571

Starting at

$56.99

per night

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Motel 6 Florence SC

2004 West Lucas St Florence, SC

With affordable rooms from $54.99, Motel 6 Florence SC provides friendly comfort for travelers bound for Laughlin, creating a warm, inviting environment perfect for rest. Take a break and relax outside your room, with select Motel 6 locations offering picnic areas or courtyards.

Guests staying at Motel 6 Florence SC will enjoy the balance of easy city access and the peaceful retreat offered by the hotel. Book a welcoming, cost-effective hotel for your Laughlin trip and save big—secure now!

  Call (855) 236-8982 to book with an agent.
  18.7 miles from Laughlin, SC 29571

Starting at

$54.99

per night

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Tru by Hilton Florence I-95

2140 West Lucas Street Florence, SC

With budget-friendly rooms starting at $138.99, Tru by Hilton Florence I-95 provides inviting accommodations for travelers to Laughlin, creating a secure environment. Enjoy the lively energy of Tru by Hilton’s public spaces, featuring fun and engaging amenities like pool tables and board games.

At Tru by Hilton Florence I-95, the peaceful surroundings provide a restful stay, while downtown Laughlin is just a convenient drive away. Make the most of your Laughlin experience with cozy, cost-effective hotel options—book now!

  Call (855) 235-0725 to book with an agent.
  18.8 miles from Laughlin, SC 29571

Starting at

$138.99

per night

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Country Inn & Suites by Radisson Florence SC

1739 Mandeville Rd Florence, SC

For those headed to Laughlin, Country Inn & Suites by Radisson Florence SC offers budget-friendly comfort with rooms starting at $150.99, creating a clean, welcoming environment perfect for unwinding. Stay active with recreational options at Country Inn & Suites, including basketball courts and mini-golf at select locations.

The tranquil setting at Country Inn & Suites by Radisson Florence SC offers a relaxing stay, with downtown Laughlin still accessible for a day of exploration. Discover how great Laughlin can be with accommodations that keep you comfortable—secure now!

  Call (855) 239-5277 to book with an agent.
  18.8 miles from Laughlin, SC 29571

Starting at

$150.99

per night

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Park Inn by Radisson Florence SC

1729 Mandeville Road Florence, SC

At Park Inn by Radisson Florence SC, travelers to Laughlin will find inviting rooms with rates beginning at $128.99, creating a warm, comfortable space ideal for relaxation. Discover the flavors of Radisson's farm-to-table dining, where locally sourced ingredients are transformed into exquisite meals.

A relaxing drive takes guests from Park Inn by Radisson Florence SC into downtown Laughlin, offering a blend of city adventure and tranquil retreat. Rest and recharge in Laughlin with accommodations that make every moment memorable—lock in today!

  Call (855) 239-4019 to book with an agent.
  18.9 miles from Laughlin, SC 29571

Starting at

$128.99

per night

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Howard Johnson by Wyndham Florence

2038 West Lucas Street Florence, SC

With affordable rooms from $79.99, Howard Johnson by Wyndham Florence provides inviting accommodations for guests bound for Laughlin, creating a warm and welcoming environment for relaxation. Appreciate the convenience of on-site dining at select Howard Johnson locations, serving delicious meals and snacks.

Enjoy a peaceful retreat at Howard Johnson by Wyndham Florence, where the calm environment is perfectly balanced with the convenience of downtown Laughlin nearby. Enjoy Laughlin with a hotel that makes affordability a top priority—book your room today!

  Call (855) 234-2997 to book with an agent.
  18.9 miles from Laughlin, SC 29571

Starting at

$79.99

per night

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La Quinta Inn & Suites by Wyndham Florence

2123 West Lucas St Florence, SC

Guests bound for Laughlin will appreciate the tucked away accommodations at La Quinta Inn & Suites by Wyndham Florence, where rooms start at $118.99, creating a welcoming atmosphere for unwinding. Enjoy a smooth check-in experience at La Quinta by Wyndham, where friendly staff are ready to greet you with a smile.

For a quiet retreat, La Quinta Inn & Suites by Wyndham Florence offers peaceful surroundings, with downtown Laughlin still within reach for a day of city exploration. Find your happy place in Laughlin with accommodations that cater to your needs and budget—secure now!

  Call (855) 235-6136 to book with an agent.
  18.9 miles from Laughlin, SC 29571

Starting at

$118.99

per night

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Days Inn by Wyndham Florence / I-95 North

2111 West Lucas St. / I 95 Florence, SC

Guests visiting Laughlin will find budget-friendly comfort at Days Inn by Wyndham Florence / I-95 North, where inviting rooms begin at $68.99, creating a clean, inviting environment perfect for rest. Take comfort in knowing our rooms offer modern conveniences and amenities, ensuring a pleasant and hassle-free stay.

Unwind at Days Inn by Wyndham Florence / I-95 North, where peaceful surroundings set the tone for a restful stay, and downtown Laughlin remains a short drive away. Stay budget-savvy and relaxed on your Laughlin adventure—lock in your hotel today!

  Call (855) 239-4019 to book with an agent.
  18.9 miles from Laughlin, SC 29571

Starting at

$68.99

per night

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