The best deals on hotels when visiting Louisville in Missouri.

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Top 24 Hotels In Louisville, Missouri 63334

Luxury Inn & Suites

107 King Dr Troy, MO

For a budget-friendly and relaxed stay, Luxury Inn & Suites offers inviting rooms with rates from $99.00, creating a warm and comfortable environment near Louisville. Enjoy a pleasant upgrade in comfort, with rooms equipped with additional amenities for a satisfying and economical visit.

Rest in the tranquility of Luxury Inn & Suites, with downtown Louisville still accessible by car for a day of sightseeing or adventure. Get ready for a Louisville visit with a hotel that makes relaxation effortless—lock in today!

  Call (855) 236-8982 to book with an agent.
  18.2 miles from Louisville, MO 63334

Starting at

$99.00

per night

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Motel 70

930 Tree Farm Road High Hill, MO

For an affordable stay near Louisville, Motel 70 offers inviting accommodations with rooms from $74.00, providing a clean, welcoming space ideal for rest. Find value in rooms that offer dependable comfort, ensuring a pleasant stay at a great price.

Discover the quiet charm of Motel 70, a relaxing retreat that’s never too far from the bustling streets of Louisville. Plan your Louisville adventure with ease and savings—secure your hotel today!

  Call (855) 235-6136 to book with an agent.
  24.9 miles from Louisville, MO 63334

Starting at

$74.00

per night

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Knights Inn New Florence

Booneslick Rd. 403 403 New Florence, MO

Guests bound for Louisville will find affordable comfort at Knights Inn New Florence, where rooms start at $89.99, providing a comforting, welcoming space perfect for rest. Experience the convenience of Knights Inn’s location, often easily accessible from major highways and roads.

Discover the tranquility of Knights Inn New Florence, where restful accommodations are perfectly balanced with proximity to Louisville. Book an inviting, budget-friendly hotel for your Louisville travels and relax—reserve now!

  Call (855) 239-4019 to book with an agent.
  25.7 miles from Louisville, MO 63334

Starting at

$89.99

per night

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Holiday Inn Express Warrenton an IHG Hotel

1008 North Highway 47 & Interstate 7 Warrenton, MO

For budget-savvy travelers headed to Louisville, Holiday Inn Express Warrenton an IHG Hotel offers warm-hearted comfort with rooms starting at $159.00, creating a clean, inviting environment. Relax with the peace of mind provided by Holiday Inn Express's enhanced cleaning measures, ensuring the highest standards of hygiene and safety.

At Holiday Inn Express Warrenton an IHG Hotel, guests can unwind in a serene setting, knowing that the lively atmosphere of Louisville is still accessible. Take advantage of Louisville travel with lodging that delivers exceptional value—book today!

  Call (855) 235-6136 to book with an agent.
  26.1 miles from Louisville, MO 63334

Starting at

$159.00

per night

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Extended Stay Warrenton Inn

220 Arlington Way Warrenton, MO

For an affordable stay near Louisville, Extended Stay Warrenton Inn offers inviting accommodations with rooms from $69.99, providing a clean, welcoming space ideal for rest. Stay healthy with Extended Stay America’s non-smoking rooms, ensuring a clean and fresh environment during your stay.

Stay at Extended Stay Warrenton Inn for the perfect blend of peaceful surroundings and quick access to the cultural offerings of Louisville. Enjoy Louisville adventures in a stress-free, affordable hotel—lock in your stay today!

  Call (855) 239-4019 to book with an agent.
  26.2 miles from Louisville, MO 63334

Starting at

$69.99

per night

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Baymont by Wyndham Warrenton

425 East Veterans Memorial Pkwy Warrenton, MO

At Baymont by Wyndham Warrenton, guests traveling to Louisville will find heartwarming accommodations with rooms from $74.99, creating a welcoming and relaxing atmosphere. Stay in touch with loved ones using Baymont by Wyndham’s free local calling, keeping you connected during your travels.

At Baymont by Wyndham Warrenton, guests can recharge in quiet surroundings while keeping Louisville's best attractions close enough to explore. Step into Louisville with a hotel that makes your visit enjoyable and cost-effective—book now!

  Call (855) 233-0132 to book with an agent.
  26.2 miles from Louisville, MO 63334

Starting at

$74.99

per night

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Super 8 by Wyndham Warrenton

1429 North Service Rd. East I 70 Warrenton, MO

For an affordable stay near Louisville, Super 8 by Wyndham Warrenton offers budget-friendly comfort with rooms from $71.99, creating a clean and warm environment. Appreciate the swift and convenient express check-out service at Super 8, perfect for guests on a tight schedule.

Guests seeking both rest and exploration will love Super 8 by Wyndham Warrenton, where peaceful lodgings are matched with easy access to Louisville. Choose comfort and affordability for your Louisville stay—book your room today!

  Call (855) 235-0725 to book with an agent.
  26.4 miles from Louisville, MO 63334

Starting at

$71.99

per night

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Quality Inn

12 Highway W Foristell, MO

With rates from $107.99, Quality Inn provides affordable comfort for guests bound for Louisville, creating a comfy and welcoming atmosphere for relaxation. Indulge in a luxury experience with Quality Inn's suite upgrades, featuring additional space and premium amenities.

Enjoy the best of both comfort and convenience at Quality Inn, where the energy of Louisville is just a short drive away. Choose a Louisville hotel that keeps you comfortable and your budget intact—reserve now!

  Call (855) 233-7850 to book with an agent.
  28.9 miles from Louisville, MO 63334

Starting at

$107.99

per night

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The Junction Inn

28804 MO 19 Perry, MO

Guests traveling to Louisville will find The Junction Inn a welcoming option, with rates beginning at $74.99, creating a inviting and comfortable environment perfect for rest. Experience a welcoming stay in rooms that provide essential amenities and a comfortable setting, all at an economical price.

Guests will love the calming atmosphere at The Junction Inn, while Louisville's activities remain just a short trip away. Stay comfortably and keep your budget intact while visiting Louisville—book your room now!

  Call (855) 233-0132 to book with an agent.
  29.3 miles from Louisville, MO 63334

Starting at

$74.99

per night

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Fairfield Inn & Suites Wentzville

130 Crossroads South Drive Wentzville, MO

With rooms beginning at $159.99, Fairfield Inn & Suites Wentzville provides inviting accommodations for travelers bound for Louisville, creating a cozy-like, welcoming environment. Experience the local engagement of Fairfield, with hotel-led tours and activities that introduce you to the community's culture and history.

Explore the sights of Louisville from the peaceful base of Fairfield Inn & Suites Wentzville, where a quiet retreat awaits you after your adventures. Relax and explore Louisville with ease, thanks to a hotel that prioritizes your comfort—secure now!

  Call (855) 236-8982 to book with an agent.
  31.2 miles from Louisville, MO 63334

Starting at

$159.99

per night

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Holiday Inn Express & Suites Wentzville St. Louis West an IHG Hotel

1100 Lodora Drive Wentzville, MO

With budget-conscious rooms beginning at $169.00, Holiday Inn Express & Suites Wentzville St. Louis West an IHG Hotel is an ideal choice for travelers to Louisville, providing a warm and comfortable space for rest. Choose Holiday Inn Express for your next group event or meeting, with comfortable accommodations and great value for all attendees.

Stay at Holiday Inn Express & Suites Wentzville St. Louis West an IHG Hotel for a quiet escape, with the added benefit of having Louisville's lively offerings just minutes away. Get the most out of Louisville with lodging that makes your visit effortless—reserve now!

  Call (855) 239-5277 to book with an agent.
  31.9 miles from Louisville, MO 63334

Starting at

$169.00

per night

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Hampton Inn St. Louis Wentzville

150 Wentzville Bluffs Drive Wentzville, MO

Guests bound for Louisville can enjoy budget-friendly comfort at Hampton Inn St. Louis Wentzville, where reassuring rooms start at $147.99, creating a welcoming space perfect for relaxation. Engage with the community at Hampton’s evening socials in select locations, featuring light bites and the chance to meet fellow travelers.

Unwind at Hampton Inn St. Louis Wentzville, a peaceful retreat offering both relaxation and the convenience of Louisville just a short drive away. Get more out of your Louisville adventure with accommodations that save you money—secure now!

  Call (855) 233-0132 to book with an agent.
  32.2 miles from Louisville, MO 63334

Starting at

$147.99

per night

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TownePlace Suites by Marriott Wentzville

20 Cliff View Drive Wentzville, MO

Stay at TownePlace Suites by Marriott Wentzville on your trip to Louisville, where comfortable accommodations create a restful escape, with inviting rates starting from just $179.99. Modern fitness centers at TownePlace Suites help you maintain your workout routine while on the road.

At TownePlace Suites by Marriott Wentzville, guests can enjoy the best of both worlds—peaceful surroundings with the vibrant energy of Louisville never far away. Discover a Louisville stay that combines elegance and affordability—book your hotel room today!

  Call (855) 236-8982 to book with an agent.
  32.2 miles from Louisville, MO 63334

Starting at

$179.99

per night

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Economy Inn Wentzville

1390 Continental Dr Wentzville, MO

With rooms starting at $67.99, Economy Inn Wentzville provides affordable comfort for guests visiting Louisville, creating a quiet, inviting space ideal for relaxation and rest. Enjoy practical comfort in rooms that offer essential amenities, making your stay both convenient and affordable.

Unwind in comfort at Economy Inn Wentzville, where guests can rest in quiet surroundings and still enjoy the convenience of Louisville. Make the most of your Louisville trip with inviting and affordable lodging—reserve today!

  Call (855) 235-0725 to book with an agent.
  32.6 miles from Louisville, MO 63334

Starting at

$67.99

per night

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Rodeway Inn

1238 West Washington St Pittsfield, IL

With affordable rooms starting at $76.99, Rodeway Inn offers inviting accommodations for travelers bound for Louisville, creating a welcoming space ideal for unwinding. Experience the convenience of rooms designed for the practical traveler, offering basic amenities and a comfortable environment.

Relax at Rodeway Inn, where spacious rooms and proximity to Louisville create an inviting atmosphere for guests. Choose a cost-effective, welcoming hotel for your Louisville visit—book now!

  Call (855) 236-8982 to book with an agent.
  33.5 miles from Louisville, MO 63334

Starting at

$76.99

per night

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Monroe Street Suites

221 South Monroe St Pittsfield, IL

At Monroe Street Suites, travelers visiting Louisville can enjoy inviting accommodations with rooms starting at $103.50, creating a warm, welcoming environment for rest. Enjoy a richer travel experience in rooms that offer additional amenities and comforts, making your stay more enjoyable and affordable.

Enjoy a quiet stay at Monroe Street Suites, perfectly positioned for those wanting both relaxation and proximity to Louisville. Choose a Louisville hotel that keeps you comfortable and your budget intact—reserve now!

  Call (855) 234-7135 to book with an agent.
  34.2 miles from Louisville, MO 63334

Starting at

$103.50

per night

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William Watson Hotel

105 East Washington Street Pittsfield, IL

Enjoy a restful stay at William Watson Hotel on your trip to Louisville, where comfortable accommodations provide relaxation, with room rates beginning at $139.99 per night. Experience a comfortable stay with upgraded amenities, ensuring a pleasant and satisfying travel experience.

Explore the sights of Louisville from the peaceful base of William Watson Hotel, where a quiet retreat awaits you after your adventures. Experience Louisville with accommodations that make every moment memorable—book today!

  Call (855) 239-4019 to book with an agent.
  34.3 miles from Louisville, MO 63334

Starting at

$139.99

per night

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Howard Johnson by Wyndham Hannibal

4141B MARKET ST Hannibal, MO

For an inviting stay, Howard Johnson by Wyndham Hannibal offers delightful rooms with rates starting at $70.00, creating a warm and welcoming space near Louisville. Discover the playful spirit of Howard Johnson through its vibrant design and cheerful service, making each stay memorable.

Find your tranquil retreat at Howard Johnson by Wyndham Hannibal, offering restful accommodations with the convenience of Louisville nearby. Make the most of your Louisville experience with extra perks at an affordable price—book now!

  Call (855) 234-2997 to book with an agent.
  35.6 miles from Louisville, MO 63334

Starting at

$70.00

per night

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Comfort Inn & Suites Hannibal

4000 Market St Hannibal, MO

Guests traveling to Louisville will appreciate the cozy-like accommodations at Comfort Inn & Suites Hannibal, with rooms starting at $112.99, creating a welcoming atmosphere. Keep up with your fitness routine in Comfort Inn's well-equipped fitness centers, maintaining your health and wellness while traveling.

Discover the balance of relaxation and adventure at Comfort Inn & Suites Hannibal, where a peaceful stay is matched with proximity to Louisville. Step into Louisville and discover a hotel that enhances your visit with added perks—secure now!

  Call (855) 236-8982 to book with an agent.
  35.7 miles from Louisville, MO 63334

Starting at

$112.99

per night

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Baymont by Wyndham Hannibal

4141 Market St Hannibal, MO

At Baymont by Wyndham Hannibal, guests bound for Louisville can enjoy inviting rooms with rates starting at $75.00, creating a clean and comfortable space ideal for relaxation. Stay productive with Baymont by Wyndham’s business centers, fully equipped with all the essentials for working on the road.

Stay at Baymont by Wyndham Hannibal for a blend of relaxation and exploration, with quiet lodgings and close proximity to Louisville. Treat yourself to a Louisville adventure where comfort and affordability go hand in hand—reserve now!

  Call (855) 233-7850 to book with an agent.
  35.7 miles from Louisville, MO 63334

Starting at

$75.00

per night

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Days Inn by Wyndham Hannibal

4070 Market St Hannibal, MO

With rooms starting at $68.00, Days Inn by Wyndham Hannibal provides affordable accommodations for travelers bound for Louisville, creating a warm and welcoming atmosphere for relaxation. Experience the friendly and vibrant atmosphere at Days Inn, making each stay pleasant and full of positive interactions.

Escape the city bustle at Days Inn by Wyndham Hannibal, where a relaxing atmosphere awaits and Louisville remains within a short drive. Make your Louisville adventure memorable and wallet-friendly—lock in your hotel room today!

  Call (855) 234-5074 to book with an agent.
  35.7 miles from Louisville, MO 63334

Starting at

$68.00

per night

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Motel 6 Hannibal MO

123 Huckleberry Heights Dr Hannibal, MO

With rates beginning at $64.99, Motel 6 Hannibal MO is a practical choice for guests visiting Louisville, creating a clean and welcoming space perfect for unwinding. Check in and check out swiftly at Motel 6, designed to get you on your way without hassle.

Guests will appreciate the serenity of Motel 6 Hannibal MO and its close proximity to all that Louisville has to offer. Enjoy added perks at a great rate for your Louisville trip—book your hotel room now!

  Call (855) 233-7850 to book with an agent.
  36.3 miles from Louisville, MO 63334

Starting at

$64.99

per night

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Super 8 by Wyndham Hannibal

120 Huckleberry Heights Dr Hannibal, MO

With budget-friendly rooms starting at $65.99, Super 8 by Wyndham Hannibal is a practical choice for travelers bound for Louisville, creating a secure and inviting space perfect for relaxation. Gain insider tips from Super 8’s local staff, who are eager to share their knowledge on the best nearby attractions and eateries.

Discover peace at Super 8 by Wyndham Hannibal, where guests can enjoy quiet rooms and still explore Louisville at their leisure. Stay budget-wise and relaxed on your Louisville visit—secure your hotel room today!

  Call (855) 239-5277 to book with an agent.
  36.3 miles from Louisville, MO 63334

Starting at

$65.99

per night

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Super 8 by Wyndham OFallon MO / St. Louis Area

987 West Terra Ln O'Fallon, MO

With rates starting at $85.00, Super 8 by Wyndham OFallon MO / St. Louis Area provides budget-conscious comfort for travelers to Louisville, creating a clean and welcoming space ideal for relaxation. Enjoy competitive rates at Super 8, ensuring you receive great value during your travels without sacrificing quality or comfort.

Discover your serene getaway at Super 8 by Wyndham OFallon MO / St. Louis Area, where the peaceful atmosphere lets you recharge while keeping Louisville nearby. Enjoy a stress-free, budget-conscious Louisville stay with added comfort—book today!

  Call (855) 239-4019 to book with an agent.
  36.4 miles from Louisville, MO 63334

Starting at

$85.00

per night

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