The best deals on hotels when visiting Matlacha in Florida.

From game day to getaway, save even more on every hotel stay.

Save up to 70% when booking as a group. Select 9+ rooms to get started.

Top 24 Hotels In Matlacha, Florida 33993

Anglers Inn

11282 Matlacha Avenue Matlacha, FL

Guests traveling to Matlacha will appreciate the reassuring comfort at Anglers Inn, where budget-friendly rooms start at $145.00, creating a warm and inviting space for rest. Stay in accommodations that offer a pleasant step up in amenities, making your stay both comfortable and economical.

Guests at Anglers Inn are never far from Matlacha’s key landmarks, with the downtown district just a short walk from the hotel. Take your Matlacha stay to the next level with affordable, well-equipped lodging—reserve now!

  Call (855) 236-8982 to book with an agent.
  0.2 miles from Matlacha, FL 33993

Starting at

$145.00

per night

Read Reviews View Amenities View All Rooms

The Westin Cape Coral Resort at Marina Village

5951 Silver King Blvd. Cape Coral, FL

With a blend of style and comfort, The Westin Cape Coral Resort at Marina Village near Matlacha provides refined accommodations, with inviting nightly rates beginning at an accessible $249.99. Indulge in the luxury of Westin's Gourmet Coffee Service, featuring premium blends for a perfect morning or afternoon pick-me-up.

Guests staying at The Westin Cape Coral Resort at Marina Village will enjoy the quiet atmosphere, while downtown Matlacha is still just a drive away for a day of sightseeing and adventure. Discover how exquisite Matlacha can be with accommodations that redefine elegance—secure now!

  Call (855) 236-8982 to book with an agent.
  7.7 miles from Matlacha, FL 33993

Starting at

$249.99

per night

Read Reviews View Amenities View All Rooms

Hampton Inn & Suites Cape Coral / Fort Myers Area FL

619 South 47th Terrace Cape Coral, FL

At Hampton Inn & Suites Cape Coral / Fort Myers Area FL, travelers to Matlacha will find inviting rooms with rates beginning at $138.99, creating a warm, comfortable space ideal for relaxation. Relish the availability of complimentary hot tea and coffee in the lobby, serving as a warm welcome throughout the day.

From Hampton Inn & Suites Cape Coral / Fort Myers Area FL, guests can drive into downtown Matlacha, where they can explore the city’s most popular spots before retreating to a peaceful stay. Take your Matlacha experience to the next level with cost-effective, well-equipped lodging—reserve now!

  Call (855) 239-4019 to book with an agent.
  8.3 miles from Matlacha, FL 33993

Starting at

$138.99

per night

Read Reviews View Amenities View All Rooms

OYO Waterfront Hotel Cape Coral / Fort Myers FL

3608 Del Prado Blvd. South Cape Coral, FL

For a restful stay, OYO Waterfront Hotel Cape Coral / Fort Myers FL offers inviting accommodations with rooms starting at $92.99, creating a clean, welcoming environment perfect for travelers. Stay in accommodations that are perfect for budget-conscious travelers, offering essential amenities and a friendly welcome.

With Matlacha a drive away, guests at OYO Waterfront Hotel Cape Coral / Fort Myers FL can enjoy the peace and quiet of being slightly removed from the center while still having easy access to the city. Find the ideal base for your Matlacha adventures with a hotel that adds value—lock in today!

  Call (855) 239-4019 to book with an agent.
  8.6 miles from Matlacha, FL 33993

Starting at

$92.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express Cape Coral Fort Myers Area an IHG Hotel

1538 Cape Coral Pkwy. E Cape Coral, FL

Guests traveling to Matlacha will find budget-conscious comfort at Holiday Inn Express Cape Coral Fort Myers Area an IHG Hotel, where pleasant rooms start at $127.65, creating a welcoming atmosphere. Relax with the convenience of in-room dining at Holiday Inn Express, featuring a selection of local and international dishes.

At Holiday Inn Express Cape Coral Fort Myers Area an IHG Hotel, visitors can enjoy the calm atmosphere of the hotel, while downtown Matlacha remains easily accessible for a day of adventure. Enjoy an exceptional Matlacha stay with added perks at a budget-friendly price—reserve today!

  Call (855) 233-7850 to book with an agent.
  9.1 miles from Matlacha, FL 33993

Starting at

$127.65

per night

Read Reviews View Amenities View All Rooms

Marriott Sanibel Harbour Resort & Spa

17260 Harbour Pointe Dr Fort Myers, FL

Those exploring Matlacha will appreciate the charm of Marriott Sanibel Harbour Resort & Spa, where inviting accommodations provide a refined stay, with rates starting at an accessible $189.99. Discover the joy of Marriott's baking classes, where guests can learn to make local pastries and desserts from expert chefs.

At Marriott Sanibel Harbour Resort & Spa, visitors can unwind in peaceful surroundings, knowing that downtown Matlacha is still within reach for a day of adventure. Stay in Matlacha with a hotel that turns your getaway into a lavish experience—lock in today!

  Call (855) 239-4019 to book with an agent.
  10.4 miles from Matlacha, FL 33993

Starting at

$189.99

per night

Read Reviews View Amenities View All Rooms

Tween Waters Island Resort & Spa

15951 Captiva Drive Captiva, FL

Unwind in the pleasant surroundings of Tween Waters Island Resort & Spa on your trip to Matlacha, with quality rooms starting at an affordable rate of $229.99 per night for added comfort. Experience a comfortable stay with upgraded amenities, ensuring a pleasant and satisfying travel experience.

Travelers can unwind in the peaceful atmosphere of Tween Waters Island Resort & Spa, while the attractions of downtown Matlacha are a quick drive away. Find your ideal Matlacha stay with a hotel that delivers luxury at a budget-friendly price—secure now!

  Call (855) 239-4019 to book with an agent.
  11.1 miles from Matlacha, FL 33993

Starting at

$229.99

per night

Read Reviews View Amenities View All Rooms

Residence Inn by Marriott Fort Myers Sanibel

20371 Summerlin Road Fort Myers, FL

Stay at Residence Inn by Marriott Fort Myers Sanibel for a relaxing visit to Matlacha, where cozy-like accommodations create a warm environment, with nightly rates beginning at an affordable $254.99. Explore the vibrant surroundings of Residence Inn locations, ideally situated near dining, shopping, and entertainment venues.

Enjoy a peaceful retreat at Residence Inn by Marriott Fort Myers Sanibel, where quiet surroundings allow guests to relax, with downtown Matlacha still within reach. Take advantage of a Matlacha hotel that elevates your travel experience—lock in today!

  Call (855) 239-5277 to book with an agent.
  11.3 miles from Matlacha, FL 33993

Starting at

$254.99

per night

Read Reviews View Amenities View All Rooms

Allure Suites

9200 College Pkwy Fort Myers, FL

Relax in the welcoming ambiance of Allure Suites as you explore Matlacha, where restful accommodations provide a warm environment, with rates starting at $89.99. Relax in rooms designed for comfort and convenience, featuring a variety of modern amenities to enhance your stay.

Unwind at Allure Suites in a quiet setting, where downtown Matlacha is still within easy reach for a day of adventure. Relax in style during your Matlacha travels with a hotel that makes luxury affordable—lock in today!

  Call (855) 233-7850 to book with an agent.
  11.3 miles from Matlacha, FL 33993

Starting at

$89.99

per night

Read Reviews View Amenities View All Rooms

La Quinta Inn & Suites by Wyndham Ft. Myers Sanibel Gateway

20091 Summerlin Road Fort Myers, FL

At La Quinta Inn & Suites by Wyndham Ft. Myers Sanibel Gateway, travelers to Matlacha will find inviting rooms with rates from $121.99, creating a warm, welcoming space perfect for relaxation. Appreciate the eco-friendly initiatives at La Quinta, aiming to reduce environmental impact through sustainable practices.

Guests at La Quinta Inn & Suites by Wyndham Ft. Myers Sanibel Gateway will appreciate the quiet atmosphere, with the convenience of downtown Matlacha just a drive away. Find your comfort zone in Matlacha with a hotel that delivers great value—reserve now!

  Call (855) 236-8982 to book with an agent.
  11.4 miles from Matlacha, FL 33993

Starting at

$121.99

per night

Read Reviews View Amenities View All Rooms

Travelodge by Wyndham Fort Myers North

13353 North Cleveland Ave North Fort Myers, FL

For travelers headed to Matlacha, Travelodge by Wyndham Fort Myers North offers inviting rooms with rates beginning at $59.99, creating a clean, comfortable environment perfect for rest. Benefit from the cleanliness and safety protocols at Travelodge, ensuring a worry-free and secure stay.

From Travelodge by Wyndham Fort Myers North, a scenic drive takes guests into downtown Matlacha, offering a balance of relaxation and easy access to the city's top spots. Book an inviting hotel that won’t strain your budget for your Matlacha trip—secure today!

  Call (855) 233-0132 to book with an agent.
  11.6 miles from Matlacha, FL 33993

Starting at

$59.99

per night

Read Reviews View Amenities View All Rooms

Econo Lodge North

13301 North Cleveland Ave North Fort Myers, FL

At Econo Lodge North, travelers to Matlacha can enjoy peaceful, affordable rooms with rates starting at $84.99, creating a warm and welcoming space ideal for relaxation. Experience the practicality and convenience of vending machines at Econo Lodge, perfect for grabbing a quick snack or drink.

Guests at Econo Lodge North can enjoy a quiet retreat, with downtown Matlacha still accessible for a day of sightseeing or city adventures. Plan ahead and enjoy extra comfort at budget rates in Matlacha—book today!

  Call (855) 239-5277 to book with an agent.
  11.7 miles from Matlacha, FL 33993

Starting at

$84.99

per night

Read Reviews View Amenities View All Rooms

Best Western Fort Myers Waterfront

13021 North Cleveland Ave North Fort Myers, FL

Unwind at Best Western Fort Myers Waterfront as you explore Matlacha, where restful rooms offer relaxation and comfort, with affordable rates starting at $111.99 per night. Appreciate the modern amenities provided by Best Western, from in-room coffee makers to state-of-the-art entertainment systems.

Guests at Best Western Fort Myers Waterfront will appreciate the calm environment, with the excitement of downtown Matlacha just a short drive away. Enjoy a Matlacha visit that’s as effortless as it is enjoyable with welcoming accommodations—book today!

  Call (855) 239-5277 to book with an agent.
  11.8 miles from Matlacha, FL 33993

Starting at

$111.99

per night

Read Reviews View Amenities View All Rooms

Riverview Inn

13020 North Cleveland Avenue North Fort Myers, FL

With affordable rooms starting at $89.99, Riverview Inn provides a welcoming option for guests bound for Matlacha, creating a warm and inviting atmosphere. Stay in rooms that deliver reliable comfort and convenience, making your stay both enjoyable and affordable.

For travelers looking to balance relaxation with exploration, Riverview Inn offers tranquility while downtown Matlacha is still close enough to visit. Stay affordably and enjoy extra perks on your Matlacha adventure—reserve your room now!

  Call (855) 233-7850 to book with an agent.
  11.8 miles from Matlacha, FL 33993

Starting at

$89.99

per night

Read Reviews View Amenities View All Rooms

Hampton Inn Fort Myers Downtown

2151 Johnson Street Fort Myers, FL

Relax in style at Hampton Inn Fort Myers Downtown as you explore Matlacha, where calm rooms provide a peaceful retreat, with nightly rates beginning at an accessible $143.99. Depend on meticulous housekeeping at Hampton, where daily service ensures your room remains clean and comfortable throughout your stay.

With downtown Matlacha a scenic drive away, guests at Hampton Inn Fort Myers Downtown can balance city adventures with the relaxing atmosphere of the hotel. Find unmatched comfort and style for your Matlacha travels—book your hotel room today!

  Call (855) 234-5074 to book with an agent.
  12.3 miles from Matlacha, FL 33993

Starting at

$143.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Fort Myers Downtown Area an IHG Hotel

2431 Cleveland Ave Fort Myers, FL

Encounter a warm atmosphere at Holiday Inn Fort Myers Downtown Area an IHG Hotel as you travel to Matlacha, with comfy accommodations that start at $135.99 per night, providing a relaxing retreat. Discover the convenience of Holiday Inn's mobile app, offering features like digital check-in, room selection, and hotel information.

Rest in the tranquility of Holiday Inn Fort Myers Downtown Area an IHG Hotel, with downtown Matlacha still accessible by car for a day of sightseeing or adventure. Relax and recharge in Matlacha with accommodations that keep you feeling your best—reserve now!

  Call (855) 236-8982 to book with an agent.
  12.4 miles from Matlacha, FL 33993

Starting at

$135.99

per night

Read Reviews View Amenities View All Rooms

Luminary Hotel & Co. Autograph Collection

2200 Edwards Drive Fort Myers, FL

Those visiting Matlacha will appreciate the charm of Luminary Hotel & Co. Autograph Collection, where delightful rooms provide luxury and warmth, with nightly rates starting at just $269.99. Engage with the stories and legends that animate Autograph Collection Hotels, adding depth and texture to your travel experiences.

Travelers seeking both relaxation and proximity will find Luminary Hotel & Co. Autograph Collection ideal, with downtown Matlacha still close enough for sightseeing. Enjoy a Matlacha getaway that’s all about indulgence and comfort—reserve your accommodations now!

  Call (855) 239-4019 to book with an agent.
  12.4 miles from Matlacha, FL 33993

Starting at

$269.99

per night

Read Reviews View Amenities View All Rooms

The Banyan Hotel Fort Myers Tapestry Collection by Hilton

1520 Broadway Fort Myers, FL

Step into comfort at The Banyan Hotel Fort Myers Tapestry Collection by Hilton on your trip to Matlacha, where quality rooms create a warm stay, with affordable rates starting at just $185.99. Enjoy the personalized approach of Tapestry Collection staff, who strive to make your stay memorable through attentive service.

For a quiet retreat, The Banyan Hotel Fort Myers Tapestry Collection by Hilton offers peaceful surroundings, with the convenience of downtown Matlacha remaining nearby for city access. Get the most out of Matlacha with a hotel that creates a memorable experience from start to finish—book today!

  Call (855) 233-0132 to book with an agent.
  12.5 miles from Matlacha, FL 33993

Starting at

$185.99

per night

Read Reviews View Amenities View All Rooms

Hampton Inn & Suites Fort Myers Beach / Sanibel Gateway

11281 Summerlin Sq. Dr Fort Myers Beach, FL

Enjoy the peaceful ambiance of Hampton Inn & Suites Fort Myers Beach / Sanibel Gateway on your trip to Matlacha, where inviting rooms provide a relaxing escape, with budget-friendly rates from $139.99. Get insider tips from Hampton's friendly staff, who are always ready to share their local knowledge to enhance your stay.

For a calm and comfortable stay, Hampton Inn & Suites Fort Myers Beach / Sanibel Gateway offers peaceful surroundings while downtown Matlacha remains within easy reach by car. Find the ideal base for your Matlacha travels with a hotel that delivers excellence—reserve now!

  Call (855) 234-7135 to book with an agent.
  12.6 miles from Matlacha, FL 33993

Starting at

$139.99

per night

Read Reviews View Amenities View All Rooms

Rodeway Inn

4760 South Cleveland Ave Fort Myers, FL

With rates beginning at $80.99, Rodeway Inn is a practical option for travelers visiting Matlacha, providing a relaxing space perfect for unwinding. Experience a stay that exceeds your expectations for value, with rooms providing all the necessary amenities without the fuss.

At Rodeway Inn, travelers can unwind in calm surroundings, with the convenience of downtown Matlacha still within easy reach. Stay comfortably and on budget while exploring Matlacha—secure your hotel room today!

  Call (855) 233-0132 to book with an agent.
  12.6 miles from Matlacha, FL 33993

Starting at

$80.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express & Suites Ft. Myers Beach Sanibel Gateway an IHG Hotel

11171 Summerlin Sq. Drive Fort Myers Beach, FL

At Holiday Inn Express & Suites Ft. Myers Beach Sanibel Gateway an IHG Hotel, travelers to Matlacha will find inviting rooms with rates beginning at $142.99, creating a warm, comfortable space ideal for relaxation. Appreciate the design of Holiday Inn Express's energy-efficient buildings, part of the brand's commitment to environmental stewardship.

At Holiday Inn Express & Suites Ft. Myers Beach Sanibel Gateway an IHG Hotel, visitors can unwind in peaceful surroundings, while downtown Matlacha remains a convenient drive away for a day of city adventures. Make every day in Matlacha a pleasure with a hotel that goes above and beyond—secure now!

  Call (855) 239-5277 to book with an agent.
  12.6 miles from Matlacha, FL 33993

Starting at

$142.99

per night

Read Reviews View Amenities View All Rooms

Howard Johnson by Wyndham Ft. Myers FL

4811 South Cleveland Ave Fort Myers, FL

Guests bound for Matlacha will find budget-conscious comfort at Howard Johnson by Wyndham Ft. Myers FL, where calm rooms start at $77.99, creating a warm and welcoming environment. Experience updated comfort in our renovated properties, where contemporary amenities meet Howard Johnson’s classic hospitality.

Guests at Howard Johnson by Wyndham Ft. Myers FL can unwind in a tranquil setting, with the added benefit of downtown Matlacha being a convenient drive away. Lock in a cozy, affordable stay perfect for your Matlacha adventure—reserve now!

  Call (855) 233-7850 to book with an agent.
  12.6 miles from Matlacha, FL 33993

Starting at

$77.99

per night

Read Reviews View Amenities View All Rooms

Baymont by Wyndham Fort Myers Central

4850 South Cleveland Ave Fort Myers, FL

At Baymont by Wyndham Fort Myers Central, guests bound for Matlacha will find welcoming comfort with rooms starting at $73.99, creating a warm and inviting environment perfect for relaxation. Enjoy the variety of dining options near Baymont by Wyndham locations, offering convenient access to local flavors and cuisines.

Relax in the quiet environment of Baymont by Wyndham Fort Myers Central, where guests can enjoy peaceful surroundings and downtown Matlacha remains nearby. Experience Matlacha at its best with a hotel that ensures comfort without the high cost—reserve now!

  Call (855) 234-7135 to book with an agent.
  12.6 miles from Matlacha, FL 33993

Starting at

$73.99

per night

Read Reviews View Amenities View All Rooms

Latitude 26 Waterfront Resort & Marina

17863 San Carlos Blvd Fort Myers Beach, FL

Uncover the comfort of Latitude 26 Waterfront Resort & Marina as you journey to Matlacha, where cushy accommodations offer quality and warmth, with inviting rates starting at $129.99. Relax in accommodations that provide a blend of style and practicality, with amenities that cater to your every need.

For those looking for relaxation, Latitude 26 Waterfront Resort & Marina provides peaceful surroundings with downtown Matlacha still accessible for sightseeing. Enjoy the perks of a hotel that makes your Matlacha visit as relaxing as possible—lock in today!

  Call (855) 233-0132 to book with an agent.
  12.8 miles from Matlacha, FL 33993

Starting at

$129.99

per night

Read Reviews View Amenities View All Rooms