Top 24 Hotels In Mayesville, South Carolina 29104

At Mount Vernon Inn, guests visiting Mayesville can unwind in inviting accommodations with rooms from $57.99, creating a warm and welcoming space perfect for rest. Find comfort in rooms that are designed for affordability and practicality, offering the basics for a pleasant stay.

With a short drive into downtown Mayesville, guests at Mount Vernon Inn can balance city exploration with the hotel’s peaceful surroundings. Stay within budget while enjoying extra comfort on your Mayesville trip—book now!

Experience a welcoming environment at Hyatt Place Sumter / Downtown near Mayesville, where charming rooms offer comfort and quality, with inviting rates starting at just $146.00. Enjoy the innovative design of Hyatt Place's lobby, blending high-tech amenities with comfortable, stylish seating for a perfect gathering spot.

Guests staying at Hyatt Place Sumter / Downtown will appreciate the peaceful atmosphere, with downtown Mayesville still accessible for a day’s adventures in the city. Discover how great Mayesville can be with accommodations that go above and beyond—lock in today!

For a restful and affordable visit near Mayesville, Red Roof Inn Sumter offers hospitable accommodations with rooms starting at $79.99, creating a warm, welcoming environment. Appreciate the quiet and cleanliness of Red Roof Inn, where you can relax in comfort and wake up refreshed.

A peaceful stay awaits at Red Roof Inn Sumter, where tranquil surroundings combine with easy access to downtown Mayesville. Plan ahead and enjoy a cozy, budget-friendly stay for your Mayesville visit—reserve now!

With budget-friendly rooms from $84.99, Travelers Inn & Suites provides inviting comfort for travelers visiting Mayesville, creating a warm, welcoming space. Experience a stay that meets your essential needs, with rooms that are clean, comfortable, and conveniently located.

Escape to the quiet of Travelers Inn & Suites, where peaceful surroundings provide a restful stay and downtown Mayesville is still nearby. Take a break in Mayesville with a hotel that understands the value of your time and money—book today!

With rooms starting at $133.99, Hampton Inn Sumter provides inviting accommodations for travelers bound for Mayesville, creating a intimate-feeling and comfortable space perfect for rest. Navigate your destination with ease, thanks to Hampton's central locations, often just steps away from public transportation.

At Hampton Inn Sumter, visitors can enjoy the quiet environment, while knowing that downtown Mayesville is just a smooth drive away. Stay smart and relaxed in Mayesville with value-driven amenities—book your room now!

Guests traveling to Mayesville will find restorative comfort at Baymont by Wyndham Sumter, with budget-friendly rooms starting at $82.99, creating a warm and inviting space perfect for rest. Relax with a complimentary cup of coffee or tea in Baymont by Wyndham’s lobby, available throughout the day for all guests.

At Baymont by Wyndham Sumter, guests can enjoy a quiet environment, with downtown Mayesville still accessible for a day of exploration or adventure. Maximize your Mayesville travels with a cost-effective, comfortable hotel stay—reserve today!

At TownePlace Suites by Marriott Sumter, travelers to Mayesville will find budget-friendly rooms with rates beginning at $259.99, creating a welcoming, comforting space perfect for rest. Unwind at TownePlace Suites' outdoor spaces, including pools and BBQ areas at select locations, for relaxation and socializing.

The serene atmosphere at TownePlace Suites by Marriott Sumter provides a quiet retreat, with downtown Mayesville just a drive away for exploration and excitement. Stay in style and save while visiting Mayesville with accommodations that meet your needs—secure now!

At Holiday Inn Express Sumter an IHG Hotel, travelers to Mayesville will find inviting rooms with rates from $149.00, creating a warm, welcoming space perfect for relaxation. Stay fit while traveling with Holiday Inn Express's fitness centers, equipped with modern equipment for a productive workout.

A quiet retreat at Holiday Inn Express Sumter an IHG Hotel provides rest and relaxation, with downtown Mayesville easily reachable for city adventures. Take advantage of a Mayesville hotel that makes your visit seamless and budget-friendly—reserve now!

For a welcoming stay near Mayesville, Candlewood Suites Sumter an IHG Hotel offers mellifluous, budget-friendly rooms with rates starting at $165.99, creating a comfortable environment. Take a break and relax in Candlewood Suites' communal lounges, where you can meet other guests or simply enjoy a quiet moment.

Guests at Candlewood Suites Sumter an IHG Hotel will enjoy a calm atmosphere, while downtown Mayesville is just a convenient drive away for a day of adventure. Find your ideal blend of comfort and affordability for your Mayesville stay—book today!

With rooms starting at $129.99, Comfort Suites Sumter provides budget-friendly comfort for travelers bound for Mayesville, creating a clean, welcoming environment. Stay eco-conscious with Comfort Suites' reusable room amenities, including glass water bottles and ceramic coffee cups to minimize waste.

At Comfort Suites Sumter, travelers can enjoy a calm retreat while downtown Mayesville remains within easy reach for a day of sightseeing. Rest easy in Mayesville knowing your hotel prioritizes both relaxation and affordability—lock in today!

Guests visiting Mayesville will find inviting comfort at Sleep Inn Sumter, where enchanting rooms start at $98.99, creating a welcoming space perfect for relaxation. Relax in Sleep Inn's signature showers, featuring a contemporary design and refreshing bath amenities for a spa-like experience.

For a quiet retreat, Sleep Inn Sumter offers peaceful surroundings, with downtown Mayesville still within reach for a day of city exploration. Plan your Mayesville visit with a hotel that offers comfort without compromise—secure today!

At Tru by Hilton Sumter, guests bound for Mayesville can enjoy warm accommodations with rates starting at $131.99, creating a clean, inviting space perfect for relaxation. Enjoy the creative and healthy meal options at Tru by Hilton, catering to diverse dietary preferences and nutritional needs.

Guests can enjoy the quiet of Tru by Hilton Sumter, while downtown Mayesville remains a short drive away for all their sightseeing needs. Make every moment in Mayesville memorable with a hotel that fits your budget—reserve today!

For a comfortable and inviting stay, SpringHill Suites Sumter offers budget-conscious rooms with rates starting at $179.99, creating a clean, welcoming space near Mayesville. Stay refreshed with SpringHill Suites' complimentary tea and coffee, available in your suite and throughout the hotel.

For a relaxing getaway, SpringHill Suites Sumter provides calm surroundings while keeping downtown Mayesville within easy reach for exploration. Discover how great your Mayesville stay can be with thoughtful, cost-effective amenities—secure now!

Guests traveling to Mayesville will find inviting comfort at Americas Best Value Inn Bishopville, with budget-friendly rooms starting at $103.99, creating a warm and welcoming environment perfect for rest. Experience valuable complimentary services like breakfast and Wi-Fi, enhancing your stay without added costs.

Travelers seeking a peaceful getaway will love Americas Best Value Inn Bishopville, with its serene surroundings and easy access to downtown Mayesville. Enjoy Mayesville stress-free with a cozy, cost-effective hotel—lock in your room today!

Guests headed to Mayesville will appreciate the serene accommodations at Red Roof Inn Bishopville, where rooms begin at $84.99, creating a clean and welcoming space perfect for rest. Enjoy the simplicity of Red Roof Inn's offerings, where the focus is on providing a great stay without unnecessary extras.

At Red Roof Inn Bishopville, guests can enjoy the calm atmosphere, while downtown Mayesville is still nearby for a day of city exploration. Enjoy an affordable stay that offers comfort and convenience—secure today!

With rooms starting at $90.99, Super 8 by Wyndham Manning offers budget-friendly accommodations for guests visiting Mayesville, creating a friendly space ideal for a relaxing stay. Seek local guidance and recommendations from Super 8's front desk, enhancing your exploration and enjoyment of the area.

Travelers seeking a quiet escape can find it at Super 8 by Wyndham Manning, with easy access to downtown Mayesville for a balanced stay of rest and exploration. Make your Mayesville trip enjoyable and cost-effective—reserve your hotel room now!

At Hampton Inn Manning, travelers to Mayesville can enjoy inviting comfort with rooms beginning at $152.99, creating a welcoming environment ideal for a restful stay. Dive into the local scene with Hampton's specially curated area guides, packed with recommendations for dining, shopping, and entertainment.

Guests staying at Hampton Inn Manning will love the calm surroundings, with downtown Mayesville still accessible for all their city exploration needs. Rest well in Mayesville with accommodations that make relaxation affordable—lock in today!

For a budget-friendly stay near Mayesville, Days Inn by Wyndham Manning offers soft accommodations with rates starting at $69.99, creating a clean and comfortable environment. Relax with the added comfort of Days Inn's plush pillows and premium bedding, ensuring a good night's sleep.

At Days Inn by Wyndham Manning, guests can unwind in peaceful surroundings, while downtown Mayesville remains easily accessible for a day of exploration. Plan your Mayesville adventure with comfort and affordability in mind—book now!

For an affordable, restful stay, Quality Inn Manning I-95 offers budget-friendly rooms with rates from $94.95, creating a clean and welcoming environment ideal for travelers. Enjoy the convenience of Quality Inn's 24-hour front desk, where friendly staff are available to assist you at any time.

Guests staying at Quality Inn Manning I-95 can unwind in a peaceful retreat, with downtown Mayesville still close enough for a day of city exploration. Relax in a hotel that makes your Mayesville adventure feel special and stress-free—reserve now!

Guests traveling to Mayesville will appreciate the inviting accommodations at SureStay Hotel by Best Western Manning, where hospitable rooms start at $114.99, creating a warm, welcoming environment. Take advantage of Best Western’s bicycle rental services, a great way to explore the local area and stay active.

Guests can unwind at SureStay Hotel by Best Western Manning in peaceful surroundings, while downtown Mayesville remains easily accessible by car. Make Mayesville feel like home with well-equipped, cost-friendly accommodations—secure now!

With rates beginning at $107.99, Baymont by Wyndham Manning provides budget-friendly accommodations for travelers headed to Mayesville, creating a welcoming space ideal for relaxation. Enjoy a night in with Baymont by Wyndham’s in-room movie rental service, offering a wide selection of films for all ages.

Relax in the tranquil surroundings of Baymont by Wyndham Manning, where the calm environment makes for a peaceful stay and downtown Mayesville is still within reach. Get ready for an unforgettable Mayesville visit with thoughtfully designed, budget-friendly lodging—lock in today!

At Super 8 by Wyndham Florence SC I-95 North / Hwy 76, travelers to Mayesville can enjoy friendly, affordable rooms with rates starting at $50.99, creating a warm and welcoming space ideal for relaxation. Depend on the uniform quality and service of Super 8, where you can expect the same high standards across all locations.

Guests seeking both rest and exploration will love Super 8 by Wyndham Florence SC I-95 North / Hwy 76, where peaceful lodgings are matched with easy access to Mayesville. Enjoy practical savings and added comfort on your Mayesville trip—reserve now!

Homewood Suites by Hilton Florence offers a peaceful escape for travelers visiting Mayesville, with warm-hearted accommodations crafted for relaxation, with nightly rates beginning at $156.99. Experience the privacy and convenience of Homewood Suites' separate bedroom and living areas, ideal for families and business travelers.

At Homewood Suites by Hilton Florence, travelers will find a relaxing retreat, with Mayesville offering nearby opportunities for fun and adventure. Plan a relaxing Mayesville getaway with accommodations that prioritize your needs—book today!