Top 24 Hotels In Mayo, South Carolina 29368

With rooms starting at $127.99, Hampton Inn Spartanburg North I-85 offers inviting accommodations for travelers to Mayo, providing a welcoming space ideal for a relaxing stay. Appreciate the safety and security of Hampton’s 24-hour front desk service, providing peace of mind throughout your stay.

Stay at Hampton Inn Spartanburg North I-85 for a blend of relaxation and exploration, with quiet lodgings and close proximity to Mayo. Experience a well-rounded stay perfect for your Mayo travels—reserve today!

For an affordable stay near Mayo, Holiday Inn Express Hotel & Suites Spartanburg North an IHG Hotel offers inviting rooms with rates starting at $142.49, creating a clean and welcoming space ideal for rest. Delight in the brand's signature touches, including the welcoming scent and energizing design elements that greet you upon arrival.

For those looking to recharge, Holiday Inn Express Hotel & Suites Spartanburg North an IHG Hotel provides a serene setting without sacrificing proximity to Mayo. Experience a well-rounded stay perfect for your Mayo travels—reserve today!

At Red Roof Inn Spartanburg I-85, travelers to Mayo can find budget-conscious comfort with rooms beginning at $89.19, creating a cushy, comfortable environment for guests. Appreciate the modern touches in Red Roof Inn's renovated properties, offering a fresh and updated take on comfort.

At Red Roof Inn Spartanburg I-85, guests can appreciate the calm of being further from the city, with downtown Mayo still just a drive away for convenience. Make the most of Mayo with a comfortable, affordable hotel—book your room now!

For an affordable stay near Mayo, Best Western Plus Spartanburg offers warm-hearted rooms with rates from $113.99, creating a welcoming, comfortable atmosphere perfect for rest. Enjoy a morning workout in Best Western Plus’ well-equipped fitness centers, open early for your convenience.

Guests at Best Western Plus Spartanburg will appreciate the peaceful atmosphere, while downtown Mayo remains accessible by car for all their city adventures. Stay effortlessly in Mayo with accommodations that make relaxation simple—secure now!

For an affordable and inviting stay, Comfort Inn & Suites at I-85 offers snug rooms with rates beginning at $101.99, creating a clean and comfortable atmosphere near Mayo. Experience the convenience of Comfort Inn's express check-out service, allowing for a swift and hassle-free departure.

With downtown Mayo just a convenient drive away, guests at Comfort Inn & Suites at I-85 can explore the city’s top spots and return to the calm of the hotel. Take your Mayo experience to the next level with cost-effective, well-equipped lodging—reserve now!

Guests bound for Mayo will enjoy affordable comfort at Days Inn by Wyndham Spartanburg, where rooms start at $99.99, providing a clean, welcoming environment ideal for relaxation. Take comfort in knowing our rooms offer modern conveniences and amenities, ensuring a pleasant and hassle-free stay.

Guests at Days Inn by Wyndham Spartanburg can enjoy a more relaxed atmosphere, with the attractions of downtown Mayo still just a reasonable drive away. Enjoy Mayo in comfort and without the expense—lock in your stay today!

For an affordable and welcoming stay, Motel 6 Spartanburg Sc – Northwest / Business 85 offers budget-friendly rooms with rates from $74.99, creating a comfortable space perfect for guests bound for Mayo. Take advantage of the spacious parking at Motel 6, accommodating vehicles of all sizes, from motorcycles to RVs.

Guests staying at Motel 6 Spartanburg Sc – Northwest / Business 85 will appreciate the convenience of being close to downtown Mayo, while enjoying the peaceful retreat offered by the hotel. Stay comfortably and affordably while visiting Mayo—reserve your room now!

For those headed to Mayo, Hampton Inn Gaffney offers budget-friendly comfort with rooms starting at $137.99, creating a clean, welcoming environment perfect for unwinding. Enjoy the personal service of Hampton’s dedicated guest relations team, ready to assist with any needs or special requests.

At Hampton Inn Gaffney, guests can unwind in a peaceful setting, with downtown Mayo still just a convenient drive away for a day of adventure. Take your Mayo experience up a notch with well-appointed, wallet-friendly lodging—secure now!

Guests traveling to Mayo will find inviting accommodations at Holiday Inn Express Gaffney an IHG Hotel, where tucked away rooms start at $124.00, creating a welcoming space ideal for relaxation. Enjoy peace of mind with Holiday Inn Express's express check-out service, streamlining your departure for a quick and easy exit.

From Holiday Inn Express Gaffney an IHG Hotel, the drive into downtown Mayo is straightforward, allowing guests to explore the city’s top destinations while returning to a peaceful setting afterward. Make your Mayo travels both enjoyable and budget-friendly with inviting lodging—book today!

At Red Roof Inn Gaffney, travelers to Mayo can enjoy sheltered accommodations with rates starting at $66.49, creating a clean and welcoming space perfect for unwinding. Select Red Roof Inn for a reliable, budget-friendly option that ensures you'll have more to spend on your adventures and less on your stay.

Guests at Red Roof Inn Gaffney can enjoy the serenity of being further from the city, while downtown Mayo remains within reach for a day of exploration. Enjoy the best of Mayo with a budget-friendly hotel that delivers on value—book now!

For an inviting and budget-friendly stay near Mayo, Best Western Spartanburg Northwest offers easygoing rooms with rates beginning at $96.99, creating a clean, welcoming space. Book your stay at Best Western, where you're guaranteed a mix of warm hospitality, comfortable rooms, and reliable service.

At Best Western Spartanburg Northwest, guests can relax in a peaceful environment, with downtown Mayo just a drive away for easy access to the city’s top destinations. Enjoy your Mayo getaway with peace of mind and budget-friendly amenities—reserve now!

For a budget-friendly and heartwarming stay, Holiday Inn Spartanburg Northwest an IHG Hotel offers inviting rooms with rates from $159.00, creating a warm and comfortable environment near Mayo. Dine conveniently on-site at Holiday Inn, where you’ll find menus suitable for children and various dietary preferences.

Guests at Holiday Inn Spartanburg Northwest an IHG Hotel will appreciate the balance of city access and a quieter, more peaceful environment, with downtown Mayo still within reach. Experience a stress-free Mayo visit with accommodations that enhance your stay—reserve today!

Those visiting Mayo will find Spartanburg Marriott a refined retreat, where inviting accommodations start at affordable rates from $289.99 per night. Indulge in the luxury of Marriott's rooftop hot tubs, offering panoramic views while you soak and unwind.

Unwind in the peaceful surroundings of Spartanburg Marriott, where you can relax in comfort and still explore Mayo at your leisure. Get ready for a Mayo escape filled with upscale amenities and superior comfort—lock in today!

Guests visiting Mayo will find cozy-like comfort at Quality Inn Gaffney I-85, where budget-friendly rooms start at $82.99, creating a warm and inviting space perfect for relaxation. Relax in Quality Inn's spacious suites, equipped with comfortable seating areas and ample room to spread out.

Travelers staying at Quality Inn Gaffney I-85 will appreciate the quiet atmosphere, with downtown Mayo close enough for sightseeing. Enjoy your Mayo getaway with peace of mind and budget-friendly amenities—reserve now!

Embrace comfort and charm at AC Hotel by Marriott Spartanburg near Mayo, where relaxing accommodations create a warm ambiance, with rates starting at an accessible $349.99. Indulge in a unique evening ritual at AC Hotels, where guests gather to enjoy a taste of European culture through specialty drinks.

For those seeking both relaxation and proximity, AC Hotel by Marriott Spartanburg offers a quiet retreat with downtown Mayo nearby. Take advantage of a Mayo hotel that offers the perfect blend of comfort and sophistication—reserve now!

With rooms starting at $83.99, Baymont by Wyndham Gaffney provides budget-conscious comfort for travelers visiting Mayo, creating a comforting, inviting space for relaxation. Stay refreshed with complimentary coffee and tea available 24/7 in the lobby of Baymont by Wyndham.

For a calm escape, Baymont by Wyndham Gaffney provides quiet surroundings with the convenience of downtown Mayo being close enough for exploration. Stay worry-free in Mayo with a hotel that offers all the essentials at a great price—lock in now!

Guests visiting Mayo will find budget-conscious comfort at Super 8 by Wyndham Gaffney, with rooms starting at $87.99, creating a clean and welcoming environment ideal for rest. Rest in freshly updated rooms at Super 8, where renovations and modern amenities contribute to a pleasant and restful environment.

For a calm and comfortable stay, Super 8 by Wyndham Gaffney offers peaceful surroundings while downtown Mayo remains within easy reach by car. Enjoy Mayo without breaking the bank—lock in your cost-effective hotel stay today!

Guests bound for Mayo will appreciate the sheltered accommodations at Rodeway Inn Expo Center, with rates beginning at $79.99, creating a clean and welcoming space for relaxation. Experience rooms that are built for the budget-conscious traveler, offering essential amenities without unnecessary luxury.

Guests at Rodeway Inn Expo Center will find a peaceful escape, while downtown Mayo remains easily accessible for a day of sightseeing. Enjoy reliable comfort for your Mayo adventure—book your affordable room now!

Guests bound for Mayo can unwind at Quality Inn, where budget-friendly rooms start at $100.99, providing a warm and comfortable space ideal for a restful stay. Rest assured with Quality Inn's 100 percent satisfaction guarantee, promising a stay that meets or exceeds your expectations.

At Quality Inn, visitors can unwind in peaceful surroundings, while the excitement of downtown Mayo is still within driving distance. Make the most of your Mayo travels with comfortable, cost-saving lodging—book now!

With rooms beginning at $114.99, Days Inn by Wyndham Spartanburg Waccamaw provides affordable accommodations for guests headed to Mayo, creating a charming and comfortable space perfect for relaxation. Discover the sunny side of service at Days Inn, where the staff's friendly and attentive service brightens your day.

For those seeking both relaxation and proximity, Days Inn by Wyndham Spartanburg Waccamaw offers a quiet retreat with downtown Mayo nearby. Plan a practical, budget-friendly stay for your Mayo travels—book today!

For those headed to Mayo, Red Roof Inn Spartanburg – I-26 offers delightful, affordable accommodations with rates starting at $93.99, creating a warm and welcoming space. Appreciate Red Roof Inn's pet-friendly rooms, allowing you to travel without worrying about leaving your pets behind.

Guests at Red Roof Inn Spartanburg – I-26 can enjoy a serene escape, with downtown Mayo remaining accessible for city exploration. Book a welcoming hotel that fits your budget and enjoy Mayo stress-free—reserve now!

Choose Residence Inn by Marriott Spartanburg for your next journey to Mayo, where tucked away accommodations provide a peaceful stay, with nightly rates beginning at an affordable $129.99. Experience the convenience of Residence Inn's on-site facilities, including laundry services, fitness centers, and business amenities.

Travelers staying at Residence Inn by Marriott Spartanburg will appreciate the quiet atmosphere, with downtown Mayo close enough for sightseeing. Enjoy a seamless Mayo visit with a hotel that ensures your trip is stress-free—reserve now!

Stay comfortably at Four Points by Sheraton Spartanburg near Mayo, where restful accommodations create a plush environment, with room rates starting at $194.99. Discover the blend of modern and traditional in Sheraton’s architecture, reflecting the brand’s global footprint and local influence.

Guests at Four Points by Sheraton Spartanburg will appreciate the calm environment, while the energy of downtown Mayo remains easily accessible. Take advantage of well-appointed lodging that enhances your Mayo adventure—reserve now!

For budget-conscious travelers to Mayo, Comfort Suites at WestGate Mall offers enchanting accommodations with rates from $120.99, creating a clean and comfortable space. Stay cool and comfortable with individually controlled air conditioning in every room at Comfort Suites.

From Comfort Suites at WestGate Mall, a brief drive takes guests into downtown Mayo, where they can enjoy the city’s highlights and return to the tranquility of their stay. Make your Mayo visit memorable and stress-free with inviting amenities—lock in today!