The best deals on hotels when visiting Mayo in Virginia.

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Top 24 Hotels In Mayo, Virginia 24598

Americas Best Value Inn & Suites South Boston

2050 Philpott Rd South Boston, VA

Guests visiting Mayo will find budget-friendly comfort at Americas Best Value Inn & Suites South Boston, where alluring rooms begin at $55.99, providing a warm and welcoming environment. Relax knowing Americas Best Value Inn provides essential toiletries, minimizing what you need to pack.

Guests staying at Americas Best Value Inn & Suites South Boston can appreciate the quieter surroundings, with downtown Mayo still easily accessible for sightseeing and city exploration. Lock in a welcoming hotel for your Mayo travels and enjoy the savings—book now!

  Call (855) 239-5277 to book with an agent.
  7.6 miles from Mayo, VA 24598

Starting at

$55.99

per night

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Super 8 by Wyndham South Boston VA

1040 Bill Tuck Hwy South Boston, VA

Guests bound for Mayo can unwind in affordable comfort at Super 8 by Wyndham South Boston VA, with relaxed rooms starting at $95.99, creating a welcoming, relaxing space. Gain insider tips from Super 8’s local staff, who are eager to share their knowledge on the best nearby attractions and eateries.

The peaceful surroundings at Super 8 by Wyndham South Boston VA offer guests a quiet retreat, while downtown Mayo remains a short drive away for all their sightseeing adventures. Choose a welcoming, budget-friendly hotel for your Mayo visit—book today!

  Call (855) 239-4019 to book with an agent.
  8.0 miles from Mayo, VA 24598

Starting at

$95.99

per night

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Clarion Pointe South Boston Danville East

1074 Bill Tuck Hwy South Boston, VA

Relax at Clarion Pointe South Boston Danville East on your journey to Mayo, where refined rooms offer quality and warmth, with inviting nightly rates beginning at $102.99. Stay in accommodations that provide the epitome of luxury and comfort, with rooms designed to offer an unparalleled experience.

From Clarion Pointe South Boston Danville East, a convenient drive into downtown Mayo allows guests to enjoy the city’s highlights while returning to a quiet, restful stay. Discover how extraordinary Mayo can be with a hotel that prioritizes your comfort—secure now!

  Call (855) 236-8982 to book with an agent.
  8.0 miles from Mayo, VA 24598

Starting at

$102.99

per night

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Fairfield Inn & Suites South Boston

1120 Bill Tuck Hwy South Boston, VA

For those visiting Mayo, Fairfield Inn & Suites South Boston offers serene accommodations with rates starting at $189.99, creating a clean, inviting space ideal for rest and comfort. Relax in Fairfield's modern lobbies, inviting spaces designed for guests to socialize, work, or enjoy a moment of quiet.

The tranquil environment at Fairfield Inn & Suites South Boston offers guests a peaceful stay, with downtown Mayo just a short drive away for easy access to the city. Enjoy the best of Mayo with a hotel that puts your comfort first—lock in your room now!

  Call (855) 233-0132 to book with an agent.
  8.0 miles from Mayo, VA 24598

Starting at

$189.99

per night

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Quality Inn South Boston Danville East

2001 Seymour Drive South Boston, VA

With budget-conscious rooms from $123.99, Quality Inn South Boston Danville East provides relaxing accommodations for guests bound for Mayo, creating a clean, comfortable space. Stay productive with Quality Inn's in-room workspaces, designed to accommodate the needs of business travelers.

The peaceful surroundings at Quality Inn South Boston Danville East make for a relaxing stay, while downtown Mayo remains accessible by car for a day of city adventures. Experience Mayo worry-free with a hotel that offers everything you need—book today!

  Call (855) 235-0725 to book with an agent.
  8.6 miles from Mayo, VA 24598

Starting at

$123.99

per night

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The Berry Hill Resort & Conference Center

3105 River Road South Boston, VA

Step into refined luxury at The Berry Hill Resort & Conference Center near Mayo, where quality rooms provide a serene atmosphere, with budget-friendly rates starting from $162.99. Stay in luxurious surroundings that provide an escape from the ordinary, with rooms designed to offer every conceivable comfort.

A short drive from The Berry Hill Resort & Conference Center takes guests into downtown Mayo, where they can experience the city’s highlights before retreating to a quiet stay. Plan your dream Mayo visit with a hotel that caters to your every need—reserve now!

  Call (855) 233-0132 to book with an agent.
  9.4 miles from Mayo, VA 24598

Starting at

$162.99

per night

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Budget Inn Roxboro

1033 North Madison Blvd Roxboro, NC

Guests visiting Mayo can enjoy the affordable comfort at Budget Inn Roxboro, where intimate-feeling rooms start at $81.99, creating a warm and inviting environment. Stay in a room that simplifies your travel, offering essential conveniences and a comfortable setting at a great value.

Guests at Budget Inn Roxboro will appreciate the calming environment, with downtown Mayo still within reach for a day of city exploration. Stay affordably and comfortably on your Mayo adventure—lock in your hotel today!

  Call (855) 236-8982 to book with an agent.
  12.3 miles from Mayo, VA 24598

Starting at

$81.99

per night

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Quality Inn Roxboro South

906 Durham Road Roxboro, NC

With rates from $120.99, Quality Inn Roxboro South provides affordable comfort for guests bound for Mayo, creating a peaceful and welcoming atmosphere for relaxation. Travel without leaving your pets behind, thanks to Quality Inn's friendly pet policy, welcoming your furry companions.

Guests at Quality Inn Roxboro South will appreciate the calm retreat, with downtown Mayo remaining within easy reach for city exploration. Set yourself up for an enjoyable Mayo visit with budget-friendly accommodations—book today!

  Call (855) 234-5074 to book with an agent.
  14.4 miles from Mayo, VA 24598

Starting at

$120.99

per night

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Hampton Inn Roxboro

920 Durham Rd Roxboro, NC

For a relaxing stay near Mayo, Hampton Inn Roxboro offers enchanting accommodations with rates beginning at $160.99, creating a warm, inviting atmosphere for rest. Enjoy a unique stay at Hampton’s boutique properties, which offer a more personalized and intimate hotel experience.

At Hampton Inn Roxboro, the quiet atmosphere offers a restful stay, with the added convenience of downtown Mayo being nearby for sightseeing. Set your sights on Mayo with a hotel that makes every penny count—lock in today!

  Call (855) 233-7850 to book with an agent.
  14.4 miles from Mayo, VA 24598

Starting at

$160.99

per night

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Clarion Pointe on the lake Clarksville South Hill West

103 2nd St Clarksville, VA

At Clarion Pointe on the lake Clarksville South Hill West, travelers to Mayo will find budget-friendly rooms with rates starting at $149.99, creating a clean, welcoming environment perfect for rest. Enjoy accommodations that provide a more comfortable stay, with added amenities designed for both relaxation and convenience.

Rest in the quiet surroundings of Clarion Pointe on the lake Clarksville South Hill West, while downtown Mayo remains a comfortable drive away for city adventures. Make the most of your Mayo visit with a hotel that delivers exceptional value—reserve now!

  Call (855) 239-4019 to book with an agent.
  18.6 miles from Mayo, VA 24598

Starting at

$149.99

per night

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Quality Inn on the Lake Clarksville Boydton

101 Virginia Ave Clarksville, VA

At Quality Inn on the Lake Clarksville Boydton, travelers to Mayo can enjoy inviting accommodations with rates starting at $158.99, providing a welcoming, comfortable environment. Enjoy freshly brewed coffee in the lobby of Quality Inn, a welcome treat to energize your mornings or afternoons.

Guests staying at Quality Inn on the Lake Clarksville Boydton will appreciate the balance of easy city access and the calming retreat offered by the hotel. Enjoy a worry-free Mayo adventure with budget-conscious, well-equipped lodging—book today!

  Call (855) 233-7850 to book with an agent.
  18.7 miles from Mayo, VA 24598

Starting at

$158.99

per night

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Sleep Inn & Suites Danville Hwy 58

1483 South Boston Rd Danville, VA

For those traveling to Mayo, Sleep Inn & Suites Danville Hwy 58 offers affordable rooms with rates starting at $159.99, creating a clean, comfortable atmosphere ideal for rest. Appreciate the clean, streamlined design of Sleep Inn guest rooms, providing a clutter-free space for relaxation or work.

Step away from the hustle and bustle at Sleep Inn & Suites Danville Hwy 58, where restful lodgings are paired with the convenience of being close to Mayo. Find out how easy Mayo travel can be with a hotel that meets all your needs—secure now!

  Call (855) 233-0132 to book with an agent.
  25.1 miles from Mayo, VA 24598

Starting at

$159.99

per night

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Days Inn&Suites by Wyndham Oxford

913 Martin Luther King Jr Ave Oxford, NC

For a restful stay near Mayo, Days Inn&Suites by Wyndham Oxford offers secure accommodations with rooms from $85.99, creating a clean and comfortable environment perfect for relaxation. Enjoy the simplicity and efficiency of Days Inn's check-in and check-out process, designed to get you on your way quickly.

Step into the peaceful surroundings of Days Inn&Suites by Wyndham Oxford, a quiet retreat that’s never too far from Mayo's best activities. Stay worry-free in Mayo with a hotel that makes affordability feel luxurious—book today!

  Call (855) 233-0132 to book with an agent.
  25.3 miles from Mayo, VA 24598

Starting at

$85.99

per night

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Comfort Inn & Suites Oxford South

1000 Martin Luther King Jr. Ave Oxford, NC

For an affordable and comfortable stay, Comfort Inn & Suites Oxford South offers inviting rooms with rates starting at $103.99, creating a clean, welcoming environment near Mayo. Rest easy knowing our enhanced cleaning protocols are in place to ensure a safe and comfortable environment for all guests.

Unwind in the tranquil surroundings of Comfort Inn & Suites Oxford South, where a restful stay is paired with convenient access to Mayo. Take advantage of a Mayo hotel that makes your visit seamless and budget-friendly—reserve now!

  Call (855) 234-5074 to book with an agent.
  25.5 miles from Mayo, VA 24598

Starting at

$103.99

per night

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Best Western Windsor Inn & Suites

1292 South Boston Rd Danville, VA

With rooms starting at $103.99, Best Western Windsor Inn & Suites provides affordable accommodations for travelers visiting Mayo, creating a comforting and comfortable atmosphere. Enjoy a seamless travel experience with Best Western’s transportation services, offering airport shuttles and area transfers.

Step into the calm of Best Western Windsor Inn & Suites, where restful lodgings are paired with proximity to Mayo's vibrant streets. Plan your Mayo trip with ease, knowing your hotel offers comfort at a great rate—book now!

  Call (855) 239-5277 to book with an agent.
  25.6 miles from Mayo, VA 24598

Starting at

$103.99

per night

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The Bee Hotel Danville

420 Patton St Danville, VA

At The Bee Hotel Danville, guests bound for Mayo can enjoy inviting accommodations with rates starting at $268.99, creating a warm and welcoming environment. Relax in accommodations that go beyond the essentials, providing additional amenities for a more satisfying visit.

At The Bee Hotel Danville, you can enjoy the best of both worlds—quiet nights and quick trips into Mayo's bustling center. Rest easy in Mayo with a hotel that prioritizes your relaxation and budget—book today!

  Call (855) 233-7850 to book with an agent.
  28.2 miles from Mayo, VA 24598

Starting at

$268.99

per night

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Red Carpet Inn & Suites

1390 Piney Forest Road Danville, VA

Guests traveling to Mayo will find comforting accommodations at Red Carpet Inn & Suites, with rooms starting at $76.99, creating a warm and inviting environment ideal for relaxation. Experience reliable comfort in well-appointed rooms that offer the basics for a pleasant and budget-friendly stay.

Unwind in the peaceful surroundings of Red Carpet Inn & Suites, where you can relax in comfort and still explore Mayo at your leisure. Enjoy Mayo with a hotel that keeps you comfortable without the extra cost—reserve today!

  Call (855) 236-8982 to book with an agent.
  28.7 miles from Mayo, VA 24598

Starting at

$76.99

per night

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The Holbrook Hotel

990 Main St Danville, VA

For a comfortable stay, The Holbrook Hotel offers inviting rooms with rates beginning at $177.99, creating a warm and inviting space ideal for travelers visiting Mayo. Relax in accommodations that go beyond the essentials, providing additional amenities for a more satisfying visit.

Relax in the calm environment of The Holbrook Hotel, knowing that the many attractions of Mayo are never far away. Take advantage of inviting accommodations perfect for your Mayo visit—reserve now!

  Call (855) 233-7850 to book with an agent.
  28.7 miles from Mayo, VA 24598

Starting at

$177.99

per night

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Hampton Inn Danville VA

1098 Riverside Dr. Danville, VA

At Hampton Inn Danville VA, travelers to Mayo will find inviting rooms with rates beginning at $264.99, creating a warm, comfortable space ideal for relaxation. Discover local flavors and sights with recommendations from Hampton's friendly staff, always ready to share their favorite local tips.

At Hampton Inn Danville VA, you’ll find the perfect escape from city life, with Mayo's bustling attractions always just a short drive away. Unwind in Mayo at a hotel that provides comfort and value in every way—reserve today!

  Call (855) 239-4019 to book with an agent.
  28.8 miles from Mayo, VA 24598

Starting at

$264.99

per night

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Budget Inn Danville

1228 Piney Forest Rd Danville, VA

For those traveling to Mayo, Budget Inn Danville offers inviting, budget-friendly comfort with rooms from $71.99, creating a clean and welcoming space ideal for rest. Experience reliable comfort in well-appointed rooms that offer the basics for a pleasant and budget-friendly stay.

At Budget Inn Danville, guests can experience a relaxing stay while enjoying easy access to Mayo’s exciting attractions. Enjoy a practical, inviting stay perfect for your Mayo travels—lock in today!

  Call (855) 234-5074 to book with an agent.
  28.9 miles from Mayo, VA 24598

Starting at

$71.99

per night

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Holiday Inn Express Danville an IHG Hotel

2121 Riverside Dr Danville, VA

For an affordable and comfortable stay, Holiday Inn Express Danville an IHG Hotel offers inviting rooms with rates starting at $194.00, creating a clean, welcoming environment near Mayo. Benefit from Holiday Inn Express's strategic locations, conveniently situated near airports, highways, and popular attractions.

Unwind in style at Holiday Inn Express Danville an IHG Hotel, found in a calm setting yet keeping the energy of Mayo within easy reach. Uncover the charm of Mayo with a hotel that offers top-notch comfort for less—book today!

  Call (855) 234-2997 to book with an agent.
  28.9 miles from Mayo, VA 24598

Starting at

$194.00

per night

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Quality Inn Danville University Area

2130 Riverside Dr Danville, VA

For an affordable and comfortable stay near Mayo, Quality Inn Danville University Area offers warm accommodations with rooms beginning at $128.99, creating a welcoming environment. Trust in Quality Inn for a consistent, dependable stay, where guest satisfaction is a top priority.

Designed for both relaxation and exploration, Quality Inn Danville University Area provides the perfect base for guests visiting Mayo. Enhance your Mayo adventure with a hotel that makes every dollar count—secure now!

  Call (855) 234-7135 to book with an agent.
  29.0 miles from Mayo, VA 24598

Starting at

$128.99

per night

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Courtyard by Marriott Danville

2136 Riverside Dr Danville, VA

Enjoy the charm and warmth of Courtyard by Marriott Danville when visiting Mayo, with comfortable accommodations crafted for relaxation, beginning at just $184.99 per night. Explore your destination with Courtyard's complimentary bicycle lending program, an eco-friendly way to see the sights and stay active.

Relax in the calm environment of Courtyard by Marriott Danville, knowing that the many attractions of Mayo are never far away. Discover how enjoyable Mayo can be with a hotel that offers everything you need—lock in today!

  Call (855) 235-6136 to book with an agent.
  29.0 miles from Mayo, VA 24598

Starting at

$184.99

per night

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Astoria North Extended Stay

1030 Piney Forest Rd Danville, VA

With rates starting at $72.99, Astoria North Extended Stay is a practical choice for travelers visiting Mayo, creating a warm, inviting space ideal for a restful stay. Enjoy the peace of mind with Extended Stay America’s secure property access, ensuring guest safety and privacy throughout your stay.

Find your sanctuary at Astoria North Extended Stay, a peaceful escape situated within easy reach of Mayo's best activities and venues. Make your Mayo trip simple and cost-effective—reserve your comfortable stay today!

  Call (855) 236-8982 to book with an agent.
  29.1 miles from Mayo, VA 24598

Starting at

$72.99

per night

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