The best deals on hotels when visiting Muskedine in Mississippi.

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Top 24 Hotels In Muskedine, Mississippi 38701

Tru by Hilton Greenville

600 Rayner Road Greenville, MS

With rates from $180.99, Tru by Hilton Greenville provides inviting accommodations for guests bound for Muskedine, creating a alluring and comfortable atmosphere for relaxation. Relax with the complimentary toiletries provided at Tru by Hilton, featuring high-quality products for your personal care.

From Tru by Hilton Greenville, a quick drive brings guests into downtown Muskedine, where they can explore the city’s best spots and return to a quiet retreat. Choose a hotel that makes your Muskedine experience delightful and budget-friendly—book now!

  Call (855) 234-7135 to book with an agent.
  9.3 miles from Muskedine, Middle School 38701

Starting at

$180.99

per night

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Harlows Casino Resort & Spa

4280 Harlow's Blvd Greenville, MS

Stay comfortably at Harlows Casino Resort & Spa as you explore Muskedine, where calm accommodations create a warm retreat, with inviting rates starting from $169.99. Enjoy a stay where luxury and comfort converge, with rooms that provide a lavish yet cozy atmosphere.

Relax in the serene surroundings of Harlows Casino Resort & Spa, with downtown Muskedine remaining within easy reach for a day of exploration. Take in the magic of Muskedine with a hotel that transforms your stay into pure bliss—secure now!

  Call (855) 239-5277 to book with an agent.
  10.3 miles from Muskedine, Middle School 38701

Starting at

$169.99

per night

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Americas Best Value Inn & Suites Greenville

2700 Highway 82 E Greenville, MS

With rooms beginning at $52.99, Americas Best Value Inn & Suites Greenville offers budget-friendly accommodations for travelers bound for Muskedine, creating a delightful, comfortable space. Kickstart your day with a complimentary breakfast at select locations, offering a variety of choices to suit any preference.

From Americas Best Value Inn & Suites Greenville, a scenic drive takes guests into downtown Muskedine, where they can explore the city's highlights before returning to the tranquility of the hotel. Choose a hotel that adds value to your Muskedine adventure—book your stay now!

  Call (855) 235-0725 to book with an agent.
  12.2 miles from Muskedine, Middle School 38701

Starting at

$52.99

per night

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Days Inn by Wyndham Greenville MS

2701 Highway 82 E Greenville, MS

At Days Inn by Wyndham Greenville MS, guests visiting Muskedine will find inviting accommodations with rooms beginning at $67.99, creating a warm and welcoming space ideal for relaxation. Host your next event with us, using our flexible meeting spaces and comprehensive amenities to ensure a successful gathering.

At Days Inn by Wyndham Greenville MS, guests can enjoy a quiet escape, knowing downtown Muskedine is still within driving distance for a day of exploration. Enjoy more of Muskedine for less with budget-friendly, inviting hotel rooms—book now!

  Call (855) 234-5074 to book with an agent.
  12.2 miles from Muskedine, Middle School 38701

Starting at

$67.99

per night

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Econo Lodge Greenville

3080 US 82 Greenville, MS

With budget-friendly rooms beginning at $63.00, Econo Lodge Greenville provides inviting accommodations for guests traveling to Muskedine, creating a plush and relaxing atmosphere. Value your stay at Econo Lodge, where essential accommodations are provided without unnecessary extravagance, ensuring a great price.

At Econo Lodge Greenville, guests can unwind in a calm setting, while downtown Muskedine remains easily accessible for sightseeing or city activities. Save big on your Muskedine travels and enjoy enhanced comfort—reserve today!

  Call (855) 234-7135 to book with an agent.
  12.3 miles from Muskedine, Middle School 38701

Starting at

$63.00

per night

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Holiday Inn Express&Suites Greenville an IHG Hotel

3090 Highway 82 East Greenville, MS

For an inviting and restful stay, Holiday Inn Express&Suites Greenville an IHG Hotel offers snug accommodations with rates starting at $155.99, creating a comfortable space near Muskedine. Delight in the brand's signature touches, including the welcoming scent and energizing design elements that greet you upon arrival.

Relax in the quiet of Holiday Inn Express&Suites Greenville an IHG Hotel, with the vibrant heart of downtown Muskedine still easily accessible by car for sightseeing. Find out how affordable and enjoyable your Muskedine visit can be—reserve your room now!

  Call (855) 239-4019 to book with an agent.
  12.3 miles from Muskedine, Middle School 38701

Starting at

$155.99

per night

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The Skylight

745 Washington Avenue Greenville, MS

For an inviting stay near Muskedine, The Skylight offers budget-friendly rooms with rates from $124.00, creating a clean and comfortable space ideal for rest. Enjoy a balanced blend of value and comfort, with accommodations designed to make your stay both pleasant and economical.

Unwind in the calm environment of The Skylight, where peaceful surroundings provide a relaxing stay and downtown Muskedine is nearby. Make the most of your Muskedine stay with budget-friendly, inviting lodging—book now!

  Call (855) 239-4019 to book with an agent.
  13.4 miles from Muskedine, Middle School 38701

Starting at

$124.00

per night

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Rodeway Inn

137 North Walnut Street Greenville, MS

For budget-savvy travelers to Muskedine, Rodeway Inn offers inviting accommodations with rooms from $66.99, creating a warm, comfortable environment for rest. Experience the essentials in rooms that provide dependable amenities, making your stay both pleasant and affordable.

Guests at Rodeway Inn will appreciate the quiet atmosphere, while a smooth drive delivers them to the sights and attractions of downtown Muskedine. Book a comfortable, budget-friendly stay for your Muskedine visit today!

  Call (855) 235-6136 to book with an agent.
  13.7 miles from Muskedine, Middle School 38701

Starting at

$66.99

per night

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Days Inn by Wyndham Lake Village

912 Highway 65 / 82 South Lake Village, AR

Guests bound for Muskedine will find budget-conscious comfort at Days Inn by Wyndham Lake Village, with quiet rooms starting at $67.99, creating a clean, inviting environment for relaxation. Utilize our business centers, equipped with essential tools and technology, to keep up with work while traveling.

For a serene getaway, Days Inn by Wyndham Lake Village offers the perfect balance of tranquility and access to downtown Muskedine for a day of adventure. Plan your Muskedine experience with a practical, budget-conscious hotel—book now!

  Call (855) 236-8982 to book with an agent.
  19.1 miles from Muskedine, Middle School 38701

Starting at

$67.99

per night

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Super 8 by Wyndham Indianola

601 Highway 82 W Indianola, MS

With rooms beginning at $79.99, Super 8 by Wyndham Indianola provides affordable comfort for travelers to Muskedine, creating a calm and inviting space ideal for relaxation. Simplify your departure with Super 8's express check-out service, ensuring a quick and hassle-free exit.

Enjoy the tranquil atmosphere of Super 8 by Wyndham Indianola, offering a peaceful stay with the benefit of easy access to Muskedine.. Stay relaxed and enjoy added comfort on your Muskedine trip—book your room today!

  Call (855) 239-4019 to book with an agent.
  24.6 miles from Muskedine, Middle School 38701

Starting at

$79.99

per night

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Americas Best Value Inn Indianola

1015 U.S. Highway 82 Indianola, MS

At Americas Best Value Inn Indianola, guests visiting Muskedine will find inviting rooms with rates starting at $55.99, providing a clean and welcoming space perfect for relaxation. Enjoy the great outdoors at select locations with picnic areas and barbecue grills available for guest use.

At Americas Best Value Inn Indianola, the quiet charm of the location is paired with the convenience of being near Muskedine's vibrant offerings. Relax in Muskedine with well-appointed lodging at a wallet-friendly rate—reserve today!

  Call (855) 239-5277 to book with an agent.
  25.4 miles from Muskedine, Middle School 38701

Starting at

$55.99

per night

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Quality Inn

910 Highway 82 E Indianola, MS

At Quality Inn, guests bound for Muskedine will find warm-hearted comfort with rooms starting at $66.99, creating a warm, inviting environment perfect for rest. Enjoy the convenience of Quality Inn's 24-hour front desk, where friendly staff are available to assist you at any time.

At Quality Inn, you can enjoy the best of both worlds—a peaceful setting and convenient access to Muskedine's vibrant attractions. Plan your Muskedine adventure with ease, knowing your accommodations are perfect—book today!

  Call (855) 234-7135 to book with an agent.
  25.6 miles from Muskedine, Middle School 38701

Starting at

$66.99

per night

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Relax Inn

1004 Highway 65 N. McGehee, AR

Guests bound for Muskedine will appreciate the budget-conscious comfort at Relax Inn, with delightful rooms starting at $63.99, creating a warm, inviting atmosphere. Relax in rooms that offer a touch more comfort, designed for travelers seeking a little extra from their budget-friendly stay.

Enjoy a refreshing stay at Relax Inn, where the comfort of spacious rooms is matched by easy access to Muskedine. Stay comfortably in Muskedine without sacrificing quality or savings—lock in your hotel today!

  Call (855) 239-5277 to book with an agent.
  35.6 miles from Muskedine, Middle School 38701

Starting at

$63.99

per night

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Lyric Hotel West End Ascend Hotel Collection

1300 Highway 8 West Cleveland, MS

Lyric Hotel West End Ascend Hotel Collection offers a relaxing stay for travelers to Muskedine, with delightful accommodations providing comfort, with nightly rates beginning at an affordable $149.00. Experience the perfect blend of style and functionality in rooms that offer enhanced amenities for a satisfying stay.

Surrounded by peace and quiet, Lyric Hotel West End Ascend Hotel Collection lets you relax while keeping the thrills of Muskedine within reach. Experience Muskedine with accommodations that make every moment memorable—book today!

  Call (855) 239-4019 to book with an agent.
  38.8 miles from Muskedine, Middle School 38701

Starting at

$149.00

per night

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Cotton House Cleveland a Tribute Portfolio Hotel

215 Cotton Row Cleveland, MS

Step into a charming escape at Cotton House Cleveland a Tribute Portfolio Hotel on your journey to Muskedine, where refined accommodations provide comfort, with nightly rates starting from $229.99. Discover Tribute Portfolio's hidden gems, from secret gardens to rooftop retreats, offering unique spaces to unwind.

Designed for both relaxation and exploration, Cotton House Cleveland a Tribute Portfolio Hotel provides the perfect base for guests visiting Muskedine. Enjoy your Muskedine getaway with a hotel that makes premium experiences accessible—book today!

  Call (855) 234-7135 to book with an agent.
  39.0 miles from Muskedine, Middle School 38701

Starting at

$229.99

per night

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Quality Inn

807 North Davis Avenue Cleveland, MS

For a comfortable stay, Quality Inn offers inviting rooms with rates beginning at $91.99, creating a warm and inviting space ideal for travelers visiting Muskedine. Relax with a book from Quality Inn's lending library, featuring a selection of popular novels and local travel guides.

Unwind at Quality Inn, a restful retreat situated just a short drive from the vibrant offerings of Muskedine. Make your Muskedine adventure both relaxing and affordable with top-notch amenities—book today!

  Call (855) 235-0725 to book with an agent.
  39.6 miles from Muskedine, Middle School 38701

Starting at

$91.99

per night

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Motel 6 Cleveland MS Delta State University

721 North Davis Ave Cleveland, MS

For a budget-friendly stay near Muskedine, Motel 6 Cleveland MS Delta State University offers tucked away accommodations with rates starting at $64.99, creating a clean and comfortable environment. Stay without surprises at Motel 6, where transparent pricing means no hidden fees and no extra charges.

Travelers will love the serene setting at Motel 6 Cleveland MS Delta State University, where peaceful accommodations offer a relaxing stay near Muskedine. Enjoy added perks at a cost-effective rate on your Muskedine adventure—secure today!

  Call (855) 236-8982 to book with an agent.
  39.9 miles from Muskedine, Middle School 38701

Starting at

$64.99

per night

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Holiday Inn Express Hotel & Suites Cleveland an IHG Hotel

808 North Davis Ave Cleveland, MS

For budget-conscious travelers headed to Muskedine, Holiday Inn Express Hotel & Suites Cleveland an IHG Hotel offers safe rooms with rates from $159.00, creating a clean and welcoming atmosphere. Relax with the added convenience of Holiday Inn Express's room service, offering a range of dining options for private enjoyment.

Escape to the peace and quiet of Holiday Inn Express Hotel & Suites Cleveland an IHG Hotel, where guests can unwind and still explore Muskedine whenever they choose. Maximize your Muskedine experience with a hotel that makes your stay unforgettable—reserve today!

  Call (855) 234-5074 to book with an agent.
  40.0 miles from Muskedine, Middle School 38701

Starting at

$159.00

per night

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Hampton Inn Yazoo City

2161 Grand Ave Yazoo City, MS

With budget-friendly rooms from $126.99, Hampton Inn Yazoo City provides inviting accommodations for guests visiting Muskedine, creating a soothing and welcoming atmosphere. Take advantage of Hampton's digital key technology, offering a secure and contactless way to access your room via smartphone.

Enjoy a peaceful stay at Hampton Inn Yazoo City, where guests can relax and still visit Muskedine's lively streets whenever they choose. Get ready for a Muskedine stay that’s as comfortable as it is affordable—reserve your room now!

  Call (855) 234-2997 to book with an agent.
  41.8 miles from Muskedine, Middle School 38701

Starting at

$126.99

per night

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The Main Street Hotel

203 South Main Street Yazoo City, MS

With rooms beginning at $95.00, The Main Street Hotel provides inviting accommodations for guests bound for Muskedine, creating a delightful and comfortable atmosphere. Enjoy the basics in well-maintained rooms that provide a comfortable and budget-friendly environment for your visit.

Enjoy a quiet stay at The Main Street Hotel, perfectly positioned for those wanting both relaxation and proximity to Muskedine. Book your Muskedine stay and experience comfort without the expense—reserve today!

  Call (855) 235-0725 to book with an agent.
  42.0 miles from Muskedine, Middle School 38701

Starting at

$95.00

per night

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Econo Lodge Yazoo City

1600 Jerry Clower Blvd Yazoo City, MS

At Econo Lodge Yazoo City, travelers to Muskedine can enjoy comfy, affordable rooms with rates starting at $75.99, creating a warm and welcoming space ideal for relaxation. Enjoy the strategic locations of Econo Lodge properties, conveniently placed for easy access to local dining, shopping, and entertainment.

Unwind in style at Econo Lodge Yazoo City, positioned in a calm setting yet keeping the energy of Muskedine within easy reach. Lock in a budget-friendly hotel that prioritizes your comfort in Muskedine—reserve today!

  Call (855) 234-7135 to book with an agent.
  42.1 miles from Muskedine, Middle School 38701

Starting at

$75.99

per night

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Days Inn by Wyndham Yazoo City

1801 Jerry Clower Blvd Yazoo City, MS

At Days Inn by Wyndham Yazoo City, guests visiting Muskedine will find affordable comfort with rooms beginning at $110.00, creating a warm and inviting space perfect for unwinding. Relax knowing Days Inn provides secure and ample parking, making it easy to come and go as you please.

Get the restful experience you crave at Days Inn by Wyndham Yazoo City, just a short distance from the exciting venues and activities of Muskedine. Make your Muskedine experience enjoyable and budget-friendly—lock in now!

  Call (855) 234-7135 to book with an agent.
  42.1 miles from Muskedine, Middle School 38701

Starting at

$110.00

per night

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Ruleville Inn by OYO

490 South Oak Ave Ruleville, MS

With affordable rooms starting at $49.00, Ruleville Inn by OYO provides restful accommodations for travelers bound for Muskedine, creating a clean, inviting space. Experience a blend of practicality and luxury in rooms that offer added amenities for a comfortable and enjoyable visit.

At Ruleville Inn by OYO, spacious accommodations and a peaceful setting make it a perfect choice for guests visiting Muskedine. Find your ideal hotel for exploring Muskedine without overspending—book your stay now!

  Call (855) 234-5074 to book with an agent.
  42.2 miles from Muskedine, Middle School 38701

Starting at

$49.00

per night

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Best Western Gateway Inn

286 Wyeth Dr Yazoo City, MS

With budget-friendly rooms starting at $119.99, Best Western Gateway Inn is ideal for guests bound for Muskedine, creating a clean and inviting space perfect for relaxation. Discover the seasonal activities offered by Best Western, from summer pool parties to winter holiday events.

Find tranquility at Best Western Gateway Inn, a peaceful retreat nestled conveniently close to Muskedine for daily adventures. Relax and recharge in Muskedine without overspending—lock in your hotel room now!

  Call (855) 239-4019 to book with an agent.
  43.4 miles from Muskedine, Middle School 38701

Starting at

$119.99

per night

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