The best deals on hotels when visiting Nyssa in Missouri.

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Top 24 Hotels In Nyssa, Missouri 63932

Bullwinkles Rustic Lodge

399 Highway T Poplar Bluff, MO

For an affordable and restful stay, Bullwinkles Rustic Lodge offers inviting accommodations with rates beginning at $89.99, creating a warm-hearted atmosphere near Nyssa. Relax in accommodations that offer added amenities and a touch of luxury, providing a comfortable and economical stay.

A short, scenic drive takes guests from Bullwinkles Rustic Lodge into downtown Nyssa, where they can explore and return to the calm of their stay. Settle into Nyssa with a hotel that offers comfort and value—secure your room now!

  Call (855) 234-5074 to book with an agent.
  11.6 miles from Nyssa, MO 63932

Starting at

$89.99

per night

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Comfort Inn Poplar Bluff North

2582 North Westwood Blvd Poplar Bluff, MO

At Comfort Inn Poplar Bluff North, travelers to Nyssa can enjoy inviting accommodations with rooms from $85.99, creating a warm and comfortable space ideal for unwinding. Savor a moment of quiet in Comfort Inn's peaceful surroundings, designed to provide a serene retreat from the day's activities.

Unwind in the peaceful environment at Comfort Inn Poplar Bluff North, with downtown Nyssa remaining close enough for a day of adventure. Embrace added comfort and convenience while exploring Nyssa—book your hotel now!

  Call (855) 239-5277 to book with an agent.
  14.1 miles from Nyssa, MO 63932

Starting at

$85.99

per night

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Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff, MO

Guests bound for Nyssa can enjoy inviting accommodations at Hampton Inn Poplar Bluff, where rooms start at $103.99, creating a warm, welcoming environment for relaxation. Earn points with Hilton Honors when you stay at Hampton, and enjoy exclusive benefits that make travel more rewarding.

Relax in the serene environment at Hampton Inn Poplar Bluff, with the vibrant energy of downtown Nyssa still within reach for a day trip. Make the most of your Nyssa visit with a hotel that delivers exceptional value—reserve now!

  Call (855) 234-5074 to book with an agent.
  14.2 miles from Nyssa, MO 63932

Starting at

$103.99

per night

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Super 8 by Wyndham Poplar Bluff Missouri

2831 North Westwood Blvd Poplar Bluff, MO

Guests visiting Nyssa will find mellifluous, budget-conscious comfort at Super 8 by Wyndham Poplar Bluff Missouri, with rates beginning at $60.99, creating a welcoming atmosphere for relaxation. Count on Super 8 for a stay that promises practicality and pleasure, making it an excellent option for economical travelers.

Guests at Super 8 by Wyndham Poplar Bluff Missouri will find a peaceful escape, while downtown Nyssa remains just a short drive away for all their city adventures. Plan your Nyssa visit with ease and budget-savvy lodging—book your room today!

  Call (855) 235-6136 to book with an agent.
  14.5 miles from Nyssa, MO 63932

Starting at

$60.99

per night

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Holiday Inn Poplar Bluff an IHG Hotel

2781 North Westwood Blvd Poplar Bluff, MO

Enjoy the peaceful surroundings of Holiday Inn Poplar Bluff an IHG Hotel near Nyssa, where quality accommodations create a relaxing escape, with rates beginning at $119.00. Engage in physical activity with Holiday Inn’s sports facilities, including tennis courts and basketball courts at select locations.

Enjoy a peaceful atmosphere at Holiday Inn Poplar Bluff an IHG Hotel, where guests can relax knowing that downtown Nyssa remains close enough for exploration. Make your Nyssa adventure memorable with a hotel that offers exceptional service—reserve now!

  Call (855) 235-0725 to book with an agent.
  14.6 miles from Nyssa, MO 63932

Starting at

$119.00

per night

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Fairfield Inn & Suites by Marriott Poplar Bluff

3109 Oak Grove Poplar Bluff, MO

For budget-savvy travelers, Fairfield Inn & Suites by Marriott Poplar Bluff provides easygoing accommodations with rates beginning at $119.99, creating a clean and comfortable space near Nyssa. Savor the moment with Fairfield's thoughtful touches, from freshly baked cookies in the lobby to personalized greetings upon check-in.

At Fairfield Inn & Suites by Marriott Poplar Bluff, travelers can experience a peaceful retreat, with the added bonus of downtown Nyssa still being close enough for adventure. Find your comfort zone in Nyssa with a hotel that delivers great value—reserve now!

  Call (855) 235-0725 to book with an agent.
  15.1 miles from Nyssa, MO 63932

Starting at

$119.99

per night

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Motel 6 Poplar Bluff MO

4101 Highway 67 N Poplar Bluff, MO

With rates beginning at $75.46, Motel 6 Poplar Bluff MO is a convenient choice for travelers to Nyssa, offering budget-friendly accommodations in a welcoming setting. Utilize on-site laundry facilities at Motel 6, ideal for long stays or mid-trip refreshes.

A quiet retreat awaits guests at Motel 6 Poplar Bluff MO, with downtown Nyssa still within reach for a balanced stay of rest and adventure. Make your Nyssa adventure memorable and budget-wise—secure your hotel room now!

  Call (855) 234-7135 to book with an agent.
  16.4 miles from Nyssa, MO 63932

Starting at

$75.46

per night

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Dexter Inn

1807 West Business US Highway 60 Dexter, MO

For budget-savvy travelers, Dexter Inn offers appealing comfort with rates beginning at $62.99, creating a warm and inviting atmosphere perfect for relaxation. Experience enhanced comfort at an affordable price, with rooms that offer additional amenities for a more satisfying stay.

From Dexter Inn, a relaxing drive brings guests into downtown Nyssa, where they can explore the city’s attractions and return to the tranquility of the hotel. Maximize your Nyssa adventure with a hotel that offers unbeatable value—secure now!

  Call (855) 233-7850 to book with an agent.
  18.0 miles from Nyssa, MO 63932

Starting at

$62.99

per night

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Hickory House Inn

1802 North Outer Rd Dexter, MO

For a restful stay near Nyssa, Hickory House Inn offers budget-friendly accommodations with rooms starting at $54.99, creating a safe, welcoming atmosphere. Relax in accommodations that provide more than just the basics, offering extra comfort and convenience for a satisfying stay.

The tranquil setting at Hickory House Inn offers a relaxing stay, with downtown Nyssa still accessible for a day of exploration. Rest well in Nyssa with a hotel that offers budget-friendly and inviting lodging—secure your room now!

  Call (855) 233-0132 to book with an agent.
  18.1 miles from Nyssa, MO 63932

Starting at

$54.99

per night

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Econo Lodge Dexter

913 Outer Rd Dexter, MO

Guests bound for Nyssa can enjoy affordable comfort at Econo Lodge Dexter, with rooms beginning at $64.99, creating a relaxed and inviting atmosphere perfect for relaxation. Take a break in Econo Lodge's comfortable seating areas, ideal for relaxing or meeting up with friends and fellow travelers.

Relax in the tranquil surroundings of Econo Lodge Dexter, where the calm environment makes for a peaceful stay and downtown Nyssa is still within reach. Enjoy reliable, comfortable lodging that fits your budget in Nyssa—secure now!

  Call (855) 239-4019 to book with an agent.
  19.0 miles from Nyssa, MO 63932

Starting at

$64.99

per night

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Parkview Motel

1617 West Main Street Corning, AR

With rooms beginning at $70.99, Parkview Motel provides inviting accommodations for guests bound for Nyssa, creating a welcoming, comfortable environment. Relax in a setting that focuses on basic comforts, with rooms equipped with comfortable beds, a work area, and a clean bathroom.

Experience a refreshing stay at Parkview Motel, where guests can unwind and still explore the vibrant life of Nyssa. Make the most of your Nyssa travels with practical, inviting hotel options—lock in now!

  Call (855) 235-0725 to book with an agent.
  25.0 miles from Nyssa, MO 63932

Starting at

$70.99

per night

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Terminated Americas Best Value Inn Kennett

110 Independence Ave Kennett, MO

For a comfortable stay, Terminated Americas Best Value Inn Kennett offers budget-friendly rooms with rates from $55.99, creating a clean and welcoming space ideal for travelers visiting Nyssa. Join the Value Club loyalty program and enjoy discounts, rewards, and free stays, adding even more value to your travels.

Designed to help you unwind, Terminated Americas Best Value Inn Kennett provides both relaxation and convenient proximity to the attractions of Nyssa. Book a practical, inviting hotel for your Nyssa adventure and save—secure now!

  Call (855) 234-2997 to book with an agent.
  29.8 miles from Nyssa, MO 63932

Starting at

$55.99

per night

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Super 8 by Wyndham Kennett

1808 1st St Kennett, MO

At Super 8 by Wyndham Kennett, travelers visiting Nyssa can enjoy friendly, affordable rooms starting at $60.99, creating a comfortable, inviting environment ideal for relaxation. Leverage Super 8's local knowledge for insider tips on the best dining spots, attractions, and hidden gems in the area.

At Super 8 by Wyndham Kennett, spacious accommodations and a peaceful setting make it a perfect choice for guests visiting Nyssa. Choose a practical, inviting hotel for your Nyssa travels—lock in your stay today!

  Call (855) 233-7850 to book with an agent.
  30.1 miles from Nyssa, MO 63932

Starting at

$60.99

per night

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Econo Lodge

110 Independence Ave Kennett, MO

For those traveling to Nyssa, Econo Lodge offers inviting accommodations with rooms starting at $61.85, creating a warm and welcoming space perfect for unwinding. Unwind in the simply designed yet comfortable rooms at Econo Lodge, tailored for a stress-free and convenient stay.

Discover a peaceful stay at Econo Lodge, where guests can relax and explore Nyssa's attractions just a quick drive away. Stay relaxed and save more while exploring Nyssa—reserve your hotel today!

  Call (855) 234-2997 to book with an agent.
  30.1 miles from Nyssa, MO 63932

Starting at

$61.85

per night

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New Orleans Inn Portageville

600 US 61 Portageville, MO

For a budget-friendly stay, New Orleans Inn Portageville offers inviting rooms with rates beginning at $70.99, creating a clean and comfortable space near Nyssa. Relax in rooms that offer a no-frills approach to comfort, with essential amenities and a focus on a clean and safe environment.

At New Orleans Inn Portageville, enjoy a calming escape, perfect for those looking to explore Nyssa without staying in the middle of the action. Enjoy Nyssa from a hotel that enhances your travel experience—lock in now!

  Call (855) 239-5277 to book with an agent.
  33.7 miles from Nyssa, MO 63932

Starting at

$70.99

per night

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Travel Inn

301 Route Ad Marston, MO

Guests traveling to Nyssa will appreciate the inviting comfort at Travel Inn, where budget-friendly rooms start at $60.96, creating a warm, welcoming environment. Stay in accommodations that cater to your desire for more comfort and amenities, all while keeping your budget in mind.

Step into relaxation at Travel Inn, where calm surroundings make for a refreshing stay with Nyssa just a short trip away. Discover a Nyssa stay that makes every moment worthwhile with practical, cost-saving lodging—lock in today!

  Call (855) 239-5277 to book with an agent.
  35.9 miles from Nyssa, MO 63932

Starting at

$60.96

per night

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Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel

115 Hospitality Dr Sikeston, MO

Guests bound for Nyssa will enjoy budget-conscious comfort at Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel, with rooms starting at $144.00, creating a warm and inviting atmosphere. Discover the convenience of Holiday Inn Express locations, perfectly positioned for easy access to local business centers and leisure attractions.

At Holiday Inn Express & Suites Sikeston Southwest an IHG Hotel, guests can recharge in peaceful surroundings and still have the option to explore the sights of Nyssa. Relax in Nyssa with a hotel that delivers convenience and savings—secure your room today!

  Call (855) 235-6136 to book with an agent.
  39.6 miles from Nyssa, MO 63932

Starting at

$144.00

per night

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Hampton Inn Sikeston

1240 Commerce Drive Sikeston, MO

With rates beginning at $126.99, Hampton Inn Sikeston is an ideal choice for travelers visiting Nyssa, creating a easygoing and welcoming space for relaxation. Rest assured with Hampton's heightened cleaning protocols, ensuring a safe and spotless environment during your stay.

Relax and recharge at Hampton Inn Sikeston, where restful accommodations are paired with easy access to Nyssa's downtown fun. Find the perfect place to rest and refresh while visiting Nyssa—secure now!

  Call (855) 234-5074 to book with an agent.
  39.6 miles from Nyssa, MO 63932

Starting at

$126.99

per night

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Quality Inn Hayti North

1500 Highway 84 Hayti, MO

At Quality Inn Hayti North, guests traveling to Nyssa can enjoy budget-friendly rooms starting at $77.13, creating a warm and welcoming space perfect for unwinding. Discover the convenience of Quality Inn's room service app, allowing you to order food and services directly from your smartphone.

Guests can enjoy a peaceful stay at Quality Inn Hayti North, while the lively streets of Nyssa remain just a quick drive away. Embrace the best of Nyssa with a welcoming, cost-effective hotel—book your stay today!

  Call (855) 239-5277 to book with an agent.
  40.1 miles from Nyssa, MO 63932

Starting at

$77.13

per night

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Super 8 by Wyndham Sikeston / Miner Area

2609 East Malone Ave Sikeston, MO

For a budget-conscious and comfortable stay, Super 8 by Wyndham Sikeston / Miner Area offers quiet accommodations with rooms from $69.99, creating a clean and inviting space. Experience serene slumber in Super 8’s cozy accommodations, where comfort is prioritized to rejuvenate travelers.

Just a drive from Nyssa, Super 8 by Wyndham Sikeston / Miner Area offers guests a peaceful place to recharge while keeping city attractions accessible. Stay relaxed and save more while exploring Nyssa—reserve your hotel today!

  Call (855) 233-0132 to book with an agent.
  42.5 miles from Nyssa, MO 63932

Starting at

$69.99

per night

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Comfort Inn & Suites Sikeston I-55

109 Matthews Ln Sikeston, MO

Guests traveling to Nyssa can unwind at Comfort Inn & Suites Sikeston I-55, where budget-friendly rooms start at $106.99, creating a warm, inviting atmosphere ideal for rest. Experience the blend of comfort and value at Comfort Inn by Choice Hotels, a trusted choice for travelers seeking affordable accommodations.

At Comfort Inn & Suites Sikeston I-55, guests enjoy both relaxation and easy access to Nyssa, making it a great choice for a balanced getaway. Get ready for a Nyssa adventure that’s both enjoyable and cost-effective—book today!

  Call (855) 235-6136 to book with an agent.
  42.7 miles from Nyssa, MO 63932

Starting at

$106.99

per night

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Travel Inn & Suites Sikeston / Miner (i-55 Exit 67)

100 Matthews Lane Sikeston, MO

With budget-conscious rooms starting at $65.99, Travel Inn & Suites Sikeston / Miner (i-55 Exit 67) is an ideal choice for travelers to Nyssa, creating a delightful, welcoming space perfect for rest. Enjoy a stay that focuses on basic comforts and value, with rooms that are clean, comfortable, and equipped with essential amenities.

Experience a refreshing stay at Travel Inn & Suites Sikeston / Miner (i-55 Exit 67), with both spacious accommodations and convenient access to Nyssa. Make every moment in Nyssa count with a hotel that offers more for less—reserve your room now!

  Call (855) 239-5277 to book with an agent.
  42.7 miles from Nyssa, MO 63932

Starting at

$65.99

per night

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Quality Inn & Suites

2310 West Kings Highway Paragould, AR

With rates beginning at $95.99, Quality Inn & Suites provides budget-conscious accommodations for travelers visiting Nyssa, creating a soothing space ideal for rest. Appreciate the detailed cleaning practices at Quality Inn, ensuring each room is spotless and sanitized for your arrival.

Escape the urban buzz at Quality Inn & Suites, offering peaceful lodgings just a short drive from the dynamic heart of Nyssa. Step into Nyssa and discover a hotel that enhances your visit with added perks—secure now!

  Call (855) 234-5074 to book with an agent.
  42.9 miles from Nyssa, MO 63932

Starting at

$95.99

per night

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Days Inn&Suites by Wyndham Sikeston

220 South Interstate Dr Sikeston, MO

For a relaxing, affordable stay, Days Inn&Suites by Wyndham Sikeston offers budget-friendly comfort with rooms from $73.99, creating a clean and welcoming space perfect for guests. Select Days Inn for an affordable and cheerful lodging option, where you'll find reliable services and a welcoming staff.

For a tranquil experience, Days Inn&Suites by Wyndham Sikeston offers spacious accommodations with Nyssa only a short journey away. Enjoy Nyssa stress-free with a hotel that offers comfort and savings—lock in now!

  Call (855) 236-8982 to book with an agent.
  43.0 miles from Nyssa, MO 63932

Starting at

$73.99

per night

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