The best deals on hotels when visiting Perkins Crossroads in South Carolina.

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Top 24 Hotels In Perkins Crossroads, South Carolina 29541

Super 8 by Wyndham Florence SC I-95 North / Hwy 76

3783A West Palmetto Street Florence, SC

Guests bound for Perkins Crossroads will appreciate the plush accommodations at Super 8 by Wyndham Florence SC I-95 North / Hwy 76, with rates beginning at $50.99, creating a clean and welcoming space for relaxation. Stay effortlessly connected with Super 8's free high-speed Wi-Fi, ideal for both leisure and business travelers.

Guests staying at Super 8 by Wyndham Florence SC I-95 North / Hwy 76 will love how close they are to downtown Perkins Crossroads, where a short drive brings them to the city’s best attractions. Stay relaxed and enjoy budget-friendly lodging for your Perkins Crossroads visit—lock in now!

  Call (855) 239-5277 to book with an agent.
  4.6 miles from Perkins Crossroads, SC 29541

Starting at

$50.99

per night

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Aloft Florence

820 WOODY JONES BOULEVARD Florence, SC

Choose Aloft Florence when traveling to Perkins Crossroads, where comfortable accommodations provide a welcoming experience, with affordable rates starting from $154.99. Join the live music scene at Aloft's Live At Aloft Hotels events, showcasing local artists and up-and-coming bands.

At Aloft Florence, guests can enjoy the comfort of being slightly removed from the city’s busiest areas, with downtown Perkins Crossroads just a convenient drive away. Find peace and relaxation in Perkins Crossroads with a hotel that turns your trip into a dream getaway—secure now!

  Call (855) 235-0725 to book with an agent.
  5.5 miles from Perkins Crossroads, SC 29541

Starting at

$154.99

per night

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Comfort Inn & Suites

527 Woody Jones Blvd Florence, SC

For an affordable stay, Comfort Inn & Suites offers comforting rooms with rates beginning at $128.99, creating a clean and comfortable space near Perkins Crossroads. Take part in our loyalty program, reaping benefits like accelerated bookings and exclusive member rates.

The relaxing environment at Comfort Inn & Suites offers guests a calm retreat, with downtown Perkins Crossroads still within easy reach for a day of exploration. Experience Perkins Crossroads in comfort and style without overspending—lock in your room now!

  Call (855) 239-4019 to book with an agent.
  5.6 miles from Perkins Crossroads, SC 29541

Starting at

$128.99

per night

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Fairfield Inn & Suites by Marriott Florence I-20

501 Woody Jones Boulevard Florence, SC

For those visiting Perkins Crossroads, Fairfield Inn & Suites by Marriott Florence I-20 offers reassuring accommodations with rates beginning at $179.99, creating a warm, welcoming atmosphere perfect for unwinding. Experience Fairfield's thoughtfully designed rooms, offering a serene retreat with plush bedding and a cozy, inviting atmosphere.

Guests staying at Fairfield Inn & Suites by Marriott Florence I-20 will appreciate the peaceful surroundings, while downtown Perkins Crossroads is still within easy reach for a day’s adventures. Step into a welcoming Perkins Crossroads stay that delivers on both comfort and savings—lock in today!

  Call (855) 233-7850 to book with an agent.
  5.6 miles from Perkins Crossroads, SC 29541

Starting at

$179.99

per night

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Home2 Suites by Hilton Florence SC

900 Woody Jones Blvd Florence, SC

Relax at Home2 Suites by Hilton Florence SC as you explore Perkins Crossroads, where quality rooms provide a peaceful stay, with budget-friendly nightly rates from $138.99. Appreciate the convenience of valet laundry services, offering same-day dry cleaning and laundering for your clothing.

A short drive from Home2 Suites by Hilton Florence SC brings guests to downtown Perkins Crossroads, where they can explore the city’s most popular destinations and attractions. Make your Perkins Crossroads adventure memorable with top-notch amenities and budget-friendly rates—book now!

  Call (855) 239-4019 to book with an agent.
  5.6 miles from Perkins Crossroads, SC 29541

Starting at

$138.99

per night

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TownePlace Suites by Marriott Florence

2650 Hospitality Boulevard Florence, SC

At TownePlace Suites by Marriott Florence, travelers bound for Perkins Crossroads can unwind in comfortable comfort with rooms starting at $204.99, creating a warm and welcoming space for relaxation. The community atmosphere at TownePlace Suites encourages guest interactions in shared areas.

With downtown Perkins Crossroads still within reach, guests at TownePlace Suites by Marriott Florence can enjoy the best of the city before returning to a more peaceful setting. Choose a well-rounded, budget-friendly stay for your Perkins Crossroads adventure—book now!

  Call (855) 233-0132 to book with an agent.
  5.7 miles from Perkins Crossroads, SC 29541

Starting at

$204.99

per night

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Residence Inn Marriott Florence

2660 Hospitality Blvd Florence, SC

Relax in the inviting surroundings of Residence Inn Marriott Florence near Perkins Crossroads, where intimate rooms offer a peaceful escape, with nightly rates beginning at $214.99. Plan an extended stay at Residence Inn, where you'll find all the amenities you need to feel at home, no matter how long your visit.

With Perkins Crossroads a drive from Residence Inn Marriott Florence, guests can easily explore the city’s attractions and then retreat to the peace and quiet of the hotel. Find the ideal base for your Perkins Crossroads trip with accommodations that deliver on quality—lock in today!

  Call (855) 239-5277 to book with an agent.
  5.7 miles from Perkins Crossroads, SC 29541

Starting at

$214.99

per night

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Hilton Garden Inn Florence

2671 Hospitality Boulevard Florence, SC

At Hilton Garden Inn Florence, guests bound for Perkins Crossroads will find tranquil comfort with rooms starting at $125.99, creating a warm, inviting environment perfect for rest. Enjoy gathering in Hilton Garden Inn's communal dining areas, which offer a welcoming space for sharing meals and stories with other guests.

From Hilton Garden Inn Florence, a convenient drive takes guests to downtown Perkins Crossroads, where they can explore the city’s highlights before returning to the hotel’s calm setting. Plan a stress-free Perkins Crossroads visit with accommodations that fit your budget—reserve now!

  Call (855) 236-8982 to book with an agent.
  5.8 miles from Perkins Crossroads, SC 29541

Starting at

$125.99

per night

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Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel

3440 West Radio Dr Florence, SC

For budget-savvy travelers visiting Perkins Crossroads, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel offers inviting rooms with rates starting at $144.00, creating a warm and welcoming environment. Stay connected with Holiday Inn Express's global TV channels, offering entertainment and news from around the world.

From Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center an IHG Hotel, the drive into downtown Perkins Crossroads offers easy access to the city’s top destinations while providing a peaceful escape at the end of the day. Uncover an inviting and cost-effective hotel for your Perkins Crossroads travels—secure today!

  Call (855) 234-7135 to book with an agent.
  5.8 miles from Perkins Crossroads, SC 29541

Starting at

$144.00

per night

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Staybridge Suites Florence Civic Center an IHG Hotel

150 Westpark Drive Florence, SC

Encounter a warm and inviting retreat at Staybridge Suites Florence Civic Center an IHG Hotel on your journey to Perkins Crossroads, where restful rooms offer relaxation, with affordable rates from $191.96. Choose Staybridge Suites for your next business trip, where the combination of comfort, convenience, and value supports productivity and relaxation.

Guests at Staybridge Suites Florence Civic Center an IHG Hotel will appreciate the balance of city access and peaceful surroundings, with downtown Perkins Crossroads still accessible by car for easy exploration. Relax in Perkins Crossroads with a hotel that’s designed to exceed your expectations—secure now!

  Call (855) 235-6136 to book with an agent.
  5.8 miles from Perkins Crossroads, SC 29541

Starting at

$191.96

per night

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Homewood Suites by Hilton Florence

3450 West Radio Drive Florence, SC

Relax in the snug surroundings of Homewood Suites by Hilton Florence near Perkins Crossroads, where comfortable rooms create a warm atmosphere, with inviting rates beginning at $156.99 per night. Experience the warm hospitality and attentive service that Homewood Suites by Hilton is known for, making you feel at home.

From Homewood Suites by Hilton Florence, a simple drive delivers guests to downtown Perkins Crossroads, where they can enjoy the city’s top attractions before returning to tranquility. Take the stress out of Perkins Crossroads travel with a hotel that’s designed for your comfort—secure now!

  Call (855) 239-4019 to book with an agent.
  5.8 miles from Perkins Crossroads, SC 29541

Starting at

$156.99

per night

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Red Roof Inn Florence Civic Center

2690 David H McLeod Boulevard Florence, SC

At Red Roof Inn Florence Civic Center, travelers bound for Perkins Crossroads will find comfortable, budget-friendly accommodations with rooms beginning at $69.00, creating a warm space for rest. Enjoy the simplicity and relaxation of Red Roof Inn’s rooms, where comfort is crafted to enhance your stay.

Guests at Red Roof Inn Florence Civic Center will love how easily they can drive into downtown Perkins Crossroads for a day of exploring, before returning to a peaceful retreat. Choose value-driven comfort for your Perkins Crossroads visit—book your affordable stay today!

  Call (855) 233-7850 to book with an agent.
  5.9 miles from Perkins Crossroads, SC 29541

Starting at

$69.00

per night

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SpringHill Suites by Marriott Florence

2670 Hospitality Blvd Florence, SC

Choose SpringHill Suites by Marriott Florence for a peaceful visit to Perkins Crossroads, where restful rooms provide warmth and relaxation, with inviting rates beginning at $152.99 per night. Rely on the trusted quality of SpringHill Suites by Marriott, a brand committed to high standards of guest satisfaction.

With downtown Perkins Crossroads a convenient drive from SpringHill Suites by Marriott Florence, guests can easily explore the city’s highlights while returning to a peaceful, quiet stay afterward. Maximize your Perkins Crossroads experience with a hotel that combines convenience and savings—lock in today!

  Call (855) 233-7850 to book with an agent.
  5.9 miles from Perkins Crossroads, SC 29541

Starting at

$152.99

per night

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Courtyard by Marriott Florence

2680 Hospitality Blvd Florence, SC

Stay at Courtyard by Marriott Florence for a relaxing retreat near Perkins Crossroads, where warm-hearted rooms create a welcoming ambiance, with inviting rates from $149.99 per night. Savor the fresh Starbucks® coffee available at Courtyard's Bistro, a welcome boost to start your day or recharge in the afternoon.

Guests at Courtyard by Marriott Florence will appreciate the quiet surroundings, with downtown Perkins Crossroads just a convenient drive away for a day of city exploration. Stay smart and relaxed in Perkins Crossroads with a hotel that offers superior comfort—secure now!

  Call (855) 234-5074 to book with an agent.
  5.9 miles from Perkins Crossroads, SC 29541

Starting at

$149.99

per night

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Hampton Inn & Suites Florence Center

3000 West Radio Dr Florence, SC

Guests bound for Perkins Crossroads will find easygoing accommodations at Hampton Inn & Suites Florence Center, with rooms starting at $151.99, creating a clean and welcoming space perfect for relaxation. Enjoy a unique stay at Hampton’s boutique properties, which offer a more personalized and intimate hotel experience.

Guests staying at Hampton Inn & Suites Florence Center will enjoy a peaceful retreat, with downtown Perkins Crossroads just a drive away for easy access to all the city’s attractions. Take advantage of extra features and affordability while exploring Perkins Crossroads—lock in now!

  Call (855) 233-7850 to book with an agent.
  6.0 miles from Perkins Crossroads, SC 29541

Starting at

$151.99

per night

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Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence, SC

With rates starting at $78.99, Days Inn by Wyndham Florence Near Civic Center is ideal for guests bound for Perkins Crossroads, providing hospitable accommodations in a warm, inviting setting. Experience the convenience of Days Inn's on-site dining options, serving delicious meals and snacks throughout the day.

From Days Inn by Wyndham Florence Near Civic Center, a brief drive brings guests into downtown Perkins Crossroads, where they can explore the city’s highlights and return to a restful stay. Embrace added comfort and convenience while exploring Perkins Crossroads—book your hotel now!

  Call (855) 233-0132 to book with an agent.
  6.1 miles from Perkins Crossroads, SC 29541

Starting at

$78.99

per night

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Quality Inn&Suites Civic

150 Dunbarton Dr Florence, SC

For a welcoming stay, Quality Inn&Suites Civic offers budget-friendly rooms with rates from $95.99, creating a clean and inviting space perfect for guests bound for Perkins Crossroads. Make the most of your travel dollars at Quality Inn, where competitive rates offer great value without sacrificing quality.

With downtown Perkins Crossroads a quick drive away, guests at Quality Inn&Suites Civic can balance city exploration with the hotel’s serene atmosphere. Uncover the best of Perkins Crossroads with a hotel that makes quality affordable—secure your room now!

  Call (855) 233-7850 to book with an agent.
  6.1 miles from Perkins Crossroads, SC 29541

Starting at

$95.99

per night

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Hyatt Place Florence Downtown

100 East Evans St. Florence Florence, SC

Find a hospitable escape at Hyatt Place Florence Downtown when visiting Perkins Crossroads, where quality rooms create a relaxing stay, with rates starting at an accessible $179.00. Experience personalized service from the Gallery Hosts at Hyatt Place, always ready to assist you with any request, day or night.

At Hyatt Place Florence Downtown, guests can enjoy the calm and comfort of being further from the city, while still having downtown Perkins Crossroads within easy reach for a day of adventure. Discover the ease of staying in Perkins Crossroads with accommodations that make travel simple—secure now!

  Call (855) 233-7850 to book with an agent.
  6.8 miles from Perkins Crossroads, SC 29541

Starting at

$179.00

per night

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Hotel Florence Tapestry Collection by Hilton

126 West Evans St Florence, SC

Uncover a warm and hospitable stay at Hotel Florence Tapestry Collection by Hilton on your trip to Perkins Crossroads, where quality accommodations provide comfort, with inviting rates from $163.99. Explore each hotel's unique architecture and design, often reflective of the building's history and cultural significance.

Guests at Hotel Florence Tapestry Collection by Hilton can balance city adventures with a more tranquil stay, as downtown Perkins Crossroads is easily accessible by car. Plan your perfect Perkins Crossroads adventure with accommodations that make your stay memorable—reserve now!

  Call (855) 234-7135 to book with an agent.
  7.0 miles from Perkins Crossroads, SC 29541

Starting at

$163.99

per night

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Baymont Inn & Suites Florence by Wyndham

1826 West Lucas Street Florence, SC

At Baymont Inn & Suites Florence by Wyndham, guests visiting Perkins Crossroads can enjoy affordable comfort with rooms starting at $43.99, creating a warm and welcoming environment perfect for unwinding. Relax in the intimate and friendly environment of Baymont by Wyndham, designed to make every traveler feel right at home.

From Baymont Inn & Suites Florence by Wyndham, the drive into downtown Perkins Crossroads offers guests the flexibility to explore the city’s highlights while retreating to a more relaxed environment afterward. Relax in Perkins Crossroads with well-appointed lodging at a wallet-friendly rate—reserve today!

  Call (855) 236-8982 to book with an agent.
  8.5 miles from Perkins Crossroads, SC 29541

Starting at

$43.99

per night

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Best Western Inn

1808 West Lucas Street Florence, SC

For budget-conscious travelers headed to Perkins Crossroads, Best Western Inn offers comfortable rooms starting at $79.99, creating a clean and inviting atmosphere. Enjoy the tranquility of Best Western's soundproof rooms, ensuring a quiet environment for rest or work.

At Best Western Inn, visitors can enjoy the relaxing surroundings of the hotel, while downtown Perkins Crossroads is just a convenient drive away for easy exploration. Experience Perkins Crossroads with accommodations that make every moment memorable—lock in now!

  Call (855) 236-8982 to book with an agent.
  8.5 miles from Perkins Crossroads, SC 29541

Starting at

$79.99

per night

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Super 8 by Wyndham Florence

1832 1 / 2 Lucas St. I95 Exit 164 Florence, SC

For an affordable stay, Super 8 by Wyndham Florence offers inviting accommodations with rates beginning at $68.99, creating a clean, comfortable environment near Perkins Crossroads. Utilize local insights from Super 8’s friendly staff, ready to guide you to the best nearby dining, shopping, and entertainment.

With Perkins Crossroads still within reach, guests at Super 8 by Wyndham Florence can explore the city’s most vibrant spots during the day and return to a more relaxed stay at night. Plan your Perkins Crossroads getaway with cost-effective, inviting accommodations—book now!

  Call (855) 234-7135 to book with an agent.
  8.5 miles from Perkins Crossroads, SC 29541

Starting at

$68.99

per night

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Suburban Studios Florence I-95

1914 West Lucas St Florence, SC

For travelers headed to Perkins Crossroads, Suburban Studios Florence I-95 offers inviting rooms with rates beginning at $56.99, creating a clean, comfortable environment perfect for rest. Find value in clean, comfortable rooms that provide dependable comfort and a welcoming environment.

Guests staying at Suburban Studios Florence I-95 will love the balance of easy city access and the quiet, peaceful setting of the hotel, ideal for a relaxing stay. Stay relaxed and within budget while exploring Perkins Crossroads—reserve your room today!

  Call (855) 239-4019 to book with an agent.
  8.5 miles from Perkins Crossroads, SC 29541

Starting at

$56.99

per night

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Econo Lodge

1916 West Lucas St Florence, SC

Guests traveling to Perkins Crossroads can unwind at Econo Lodge, where inviting rooms start at $56.99, creating a soft and welcoming environment perfect for relaxation. Explore the surroundings with help from Econo Lodge's staff, who can provide recommendations for dining, shopping, and local attractions.

At Econo Lodge, guests can enjoy a more spacious and quiet stay, while downtown Perkins Crossroads remains within reach for easy access to the city’s main attractions. Lock in an affordable, welcoming stay for your Perkins Crossroads visit—reserve your room now!

  Call (855) 234-7135 to book with an agent.
  8.6 miles from Perkins Crossroads, SC 29541

Starting at

$56.99

per night

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