The best deals on hotels when visiting Saco in Missouri.

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Top 24 Hotels In Saco, Missouri 63645

Madison Inn Lodge

730 Plaza Drive Fredericktown, MO

With rates beginning at $81.00, Madison Inn Lodge provides budget-friendly comfort for travelers bound for Saco, creating a clean, inviting space. Stay in accommodations that blend added amenities with affordability, providing a superior stay experience.

Guests staying at Madison Inn Lodge will love the serene atmosphere, while downtown Saco remains close by for all their city adventures. Choose a hotel that enhances your Saco experience with thoughtful amenities—book today!

  Call (855) 235-0725 to book with an agent.
  15.2 miles from Saco, MO 63645

Starting at

$81.00

per night

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Shepherd Mountain Inn

1321 North Highway 21 Ironton, MO

For a comfortable and budget-friendly experience, Shepherd Mountain Inn offers pleasant rooms with rates starting at $123.30, creating a warm environment perfect for rest. Enjoy a more satisfying stay with additional amenities that offer a touch of luxury without the premium price tag.

Relax in the peaceful surroundings of Shepherd Mountain Inn, a tranquil spot nestled just a short drive from Saco's lively attractions. Stay relaxed and on budget while exploring Saco—reserve your hotel room today!

  Call (855) 233-7850 to book with an agent.
  20.3 miles from Saco, MO 63645

Starting at

$123.30

per night

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Fort Davidson Hotel

310 South McCune St Ironton, MO

Guests bound for Saco will find intimate accommodations at Fort Davidson Hotel, with rooms beginning at $125.00, creating a welcoming, comfortable atmosphere ideal for relaxation. Stay in a setting that offers increased comfort and amenities, providing a superior experience without the premium price.

Plan your ideal trip at Fort Davidson Hotel, balancing rest in a serene setting with the excitement of Saco a short drive away. Stay in style and save while visiting Saco with accommodations that meet your needs—secure now!

  Call (855) 233-0132 to book with an agent.
  20.7 miles from Saco, MO 63645

Starting at

$125.00

per night

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Black River Motel&Restaurant

32970 Missouri Higway 21 Lesterville, MO

Guests visiting Saco can enjoy inviting accommodations at Black River Motel&Restaurant, with rooms starting at $129.99, creating a snug, welcoming environment perfect for relaxation. Enjoy standard amenities in rooms that provide a comfortable environment for a budget-friendly stay.

Guests will appreciate the serenity of Black River Motel&Restaurant and its close proximity to all that Saco has to offer. Make your Saco visit both cozy and cost-effective—secure your hotel room now!

  Call (855) 239-4019 to book with an agent.
  22.9 miles from Saco, MO 63645

Starting at

$129.99

per night

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EC Reeds Mercantile&Hotel

301 1st St Marble Hill, MO

Find your ideal retreat at EC Reeds Mercantile&Hotel as you travel to Saco, with heartwarming accommodations designed for relaxation, all from a welcoming $116.99 per night. Relax in accommodations that blend modern amenities with comfort, offering a perfect retreat for relaxation and productivity.

Find your tranquil retreat at EC Reeds Mercantile&Hotel, offering restful accommodations with the convenience of Saco nearby. Find your perfect Saco escape with a hotel that combines elegance and practicality—reserve now!

  Call (855) 236-8982 to book with an agent.
  25.6 miles from Saco, MO 63645

Starting at

$116.99

per night

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Baymont Inn&Suites by Wyndham Farmington MO

1625 West Columbia St Farmington, MO

For an inviting stay, Baymont Inn&Suites by Wyndham Farmington MO offers soft accommodations with rates from $57.99, creating a comfortable environment ideal for travelers bound for Saco. Experience the quaint charm of Baymont by Wyndham’s architecture, reflecting the local style and culture.

Discover the ideal balance of serenity and access at Baymont Inn&Suites by Wyndham Farmington MO, positioned just a drive away from the action in Saco. Step into Saco and discover a hotel that enhances your visit with added perks—secure now!

  Call (855) 234-2997 to book with an agent.
  28.2 miles from Saco, MO 63645

Starting at

$57.99

per night

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Quality Inn Farmington

1400 West Liberty St Farmington, MO

Guests visiting Saco can enjoy affordable comfort at Quality Inn Farmington, where plush rooms start at $54.00, creating a warm and inviting space ideal for unwinding. Wake up to a complimentary hot breakfast at Quality Inn, where a variety of delicious options await to kickstart your day.

At Quality Inn Farmington, you’ll find both relaxation and the ease of reaching Saco's bustling attractions in no time. Rest and recharge in Saco with accommodations that make every moment memorable—lock in today!

  Call (855) 233-0132 to book with an agent.
  28.5 miles from Saco, MO 63645

Starting at

$54.00

per night

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Super 8 by Wyndham Farmington

930 Valley Creek Dr Farmington, MO

With rooms from $57.00, Super 8 by Wyndham Farmington offers budget-conscious accommodations for travelers headed to Saco, creating a restful, comfortable environment for all guests. Get local recommendations from Super 8’s expert staff, who are always on hand to ensure you make the most of your visit.

Enjoy a quiet retreat at Super 8 by Wyndham Farmington, perfectly positioned for those seeking both relaxation and proximity to Saco. Book a welcoming hotel for your Saco travels that fits your budget—secure today!

  Call (855) 234-7135 to book with an agent.
  29.4 miles from Saco, MO 63645

Starting at

$57.00

per night

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Holiday Inn Express & Suites Farmington an IHG Hotel

820 Market St Farmington, MO

With rooms starting at $199.00, Holiday Inn Express & Suites Farmington an IHG Hotel provides affordable accommodations for travelers visiting Saco, creating a gentle and comfortable atmosphere. Appreciate the eco-friendly initiatives at Holiday Inn Express, including recycling bins and energy-efficient lighting.

Enjoy the serene environment of Holiday Inn Express & Suites Farmington an IHG Hotel, where peaceful lodgings provide the perfect base for exploring Saco. Make your Saco experience exceptional with a hotel that keeps costs down—lock in today!

  Call (855) 239-5277 to book with an agent.
  29.4 miles from Saco, MO 63645

Starting at

$199.00

per night

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Hampton Inn Farmington

850 Valley Creek Dr Farmington, MO

Guests traveling to Saco will appreciate the inviting comfort at Hampton Inn Farmington, where budget-friendly rooms start at $168.99, creating a warm, welcoming environment. Experience the signature Hamptonality, a commitment to friendly service, clean rooms, and comfortable surroundings every time.

Enjoy a calming retreat at Hampton Inn Farmington, where quiet surroundings and Saco's energy are just a drive apart. Enjoy the perfect Saco retreat with cost-effective lodging that doesn’t skimp on quality—lock in today!

  Call (855) 236-8982 to book with an agent.
  29.5 miles from Saco, MO 63645

Starting at

$168.99

per night

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Crown Pointe Lodge Best Western Signature Collection

4245 Hunt Rd Farmington, MO

With rooms starting at $118.99, Crown Pointe Lodge Best Western Signature Collection provides budget-conscious comfort for travelers visiting Saco, creating a calm, inviting space for relaxation. Maintain your health routine in Best Western's fully equipped fitness centers, designed to cater to all levels of exercise.

Just a drive from Saco, Crown Pointe Lodge Best Western Signature Collection offers guests a peaceful place to recharge while keeping city attractions accessible. Relax and recharge in Saco with a hotel that keeps your wallet happy—book today!

  Call (855) 236-8982 to book with an agent.
  30.9 miles from Saco, MO 63645

Starting at

$118.99

per night

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Days Inn by Wyndham Perryville

1500 Liberty St. Perryville, MO

With rooms starting at $76.00, Days Inn by Wyndham Perryville offers budget-friendly comfort for travelers visiting Saco, creating a warm-hearted environment ideal for unwinding. Experience the inviting ambience of our breakfast areas, where you can enjoy good food in good company.

Find your escape at Days Inn by Wyndham Perryville, offering the perfect blend of calm and proximity to the attractions of Saco. Enjoy Saco to the fullest with inviting, budget-friendly lodging—book now!

  Call (855) 234-5074 to book with an agent.
  37.7 miles from Saco, MO 63645

Starting at

$76.00

per night

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Holiday Inn Express & Suites Perryville an IHG Hotel

2020 Jefferson St Perryville, MO

At Holiday Inn Express & Suites Perryville an IHG Hotel, guests bound for Saco can enjoy budget-friendly accommodations with rooms starting at $149.99, creating a welcoming and comfortable space. Appreciate the cleanliness and safety protocols at Holiday Inn Express, ensuring a worry-free and healthy stay for all guests.

Take time to relax at Holiday Inn Express & Suites Perryville an IHG Hotel, where a calm setting is complemented by the convenience of being near Saco. Enjoy a hassle-free Saco visit with a hotel that makes everything easy—reserve now!

  Call (855) 239-4019 to book with an agent.
  38.0 miles from Saco, MO 63645

Starting at

$149.99

per night

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Quality Inn

1517 South Perryville Blvd. Perryville, MO

Guests bound for Saco will find inviting accommodations at Quality Inn, where comfy rooms start at $76.00, creating a warm and comfortable space perfect for relaxation. Relax in Quality Inn's whirlpool or hot tub facilities, a perfect way to unwind after a busy day.

At Quality Inn, you can experience the charm of a quiet stay with easy access to Saco's most popular attractions. Stay refreshed and relaxed in Saco with inviting, budget-friendly lodging—reserve now!

  Call (855) 233-7850 to book with an agent.
  38.1 miles from Saco, MO 63645

Starting at

$76.00

per night

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Super 8 by Wyndham Perryville

1119 Vincent Dr Perryville, MO

Guests visiting Saco can unwind in inviting comfort at Super 8 by Wyndham Perryville, with rooms beginning at $83.99, creating a clean and welcoming atmosphere ideal for relaxation. Rely on Super 8 for a consistent and dependable lodging experience, no matter where your travels take you.

Enjoy the comfort of Super 8 by Wyndham Perryville, perfectly situated for guests wanting to explore Saco while staying in a serene location. Enjoy an affordable Saco stay that doesn’t compromise on comfort—reserve today!

  Call (855) 233-0132 to book with an agent.
  38.1 miles from Saco, MO 63645

Starting at

$83.99

per night

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Super 8 by Wyndham Bonne Terre

8 Northwood Dr. Highway 67 A Bonne Terre, MO

Guests visiting Saco can enjoy inviting accommodations at Super 8 by Wyndham Bonne Terre, with rooms starting at $52.99, creating a charming, welcoming environment perfect for relaxation. Navigate your travels from Super 8's strategic outposts, perfectly positioned for easy access to highways, eateries, and local sites.

Enjoy a restful stay at Super 8 by Wyndham Bonne Terre, where calm lodgings provide a peaceful atmosphere close to Saco's offerings. Book a hotel for your Saco adventure that adds comfort without the extra cost—reserve today!

  Call (855) 234-5074 to book with an agent.
  38.8 miles from Saco, MO 63645

Starting at

$52.99

per night

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Motel 6 Poplar Bluff MO

4101 Highway 67 N Poplar Bluff, MO

For guests headed to Saco, Motel 6 Poplar Bluff MO offers restorative accommodations with rooms starting at $75.46, creating a warm and inviting space perfect for relaxation. Utilize on-site laundry facilities at Motel 6, ideal for long stays or mid-trip refreshes.

Unwind in the comfort of Motel 6 Poplar Bluff MO, where the restful ambiance ensures a peaceful stay with Saco always close by. Book now and enjoy extra comfort on your Saco adventure without the high cost!

  Call (855) 234-5074 to book with an agent.
  38.9 miles from Saco, MO 63645

Starting at

$75.46

per night

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Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff, MO

Guests bound for Saco will find soothing comfort at Hampton Inn Poplar Bluff, with inviting rooms starting at $103.99, creating a warm and welcoming space perfect for relaxation. Opt for enhanced comfort with upgraded bedding options available in select Hampton rooms, featuring premium linens for a luxurious sleep.

Rest in comfort at Hampton Inn Poplar Bluff, a quiet haven found conveniently near Saco for easy day trips and adventures. Enjoy Saco like never before with a hotel that’s practical and inviting—book today!

  Call (855) 236-8982 to book with an agent.
  39.8 miles from Saco, MO 63645

Starting at

$103.99

per night

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Fairfield Inn & Suites by Marriott Poplar Bluff

3109 Oak Grove Poplar Bluff, MO

Guests traveling to Saco will find affordable comfort at Fairfield Inn & Suites by Marriott Poplar Bluff, where comfy rooms start at $119.99, creating a warm, inviting space ideal for unwinding. Appreciate the environmental commitment of Fairfield by Marriott, with initiatives aimed at reducing waste and conserving resources.

Relax at Fairfield Inn & Suites by Marriott Poplar Bluff, where guests can unwind in quiet comfort while keeping Saco within easy reach for day trips. Get the most out of Saco with lodging that makes your visit effortless—reserve now!

  Call (855) 236-8982 to book with an agent.
  39.8 miles from Saco, MO 63645

Starting at

$119.99

per night

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Super 8 by Wyndham Poplar Bluff Missouri

2831 North Westwood Blvd Poplar Bluff, MO

Guests traveling to Saco can unwind at Super 8 by Wyndham Poplar Bluff Missouri, where inviting rooms start at $60.99, creating a soothing and welcoming environment perfect for relaxation. Immerse yourself in the local area with Super 8's strategic locations, providing easy access to explore and discover new experiences.

At Super 8 by Wyndham Poplar Bluff Missouri, guests are invited to relax in spacious rooms, knowing that the vibrant life of Saco is just a drive away. Make your Saco experience cost-effective and relaxing—secure your stay now!

  Call (855) 234-2997 to book with an agent.
  39.9 miles from Saco, MO 63645

Starting at

$60.99

per night

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Holiday Inn Poplar Bluff an IHG Hotel

2781 North Westwood Blvd Poplar Bluff, MO

Enjoy a welcoming retreat at Holiday Inn Poplar Bluff an IHG Hotel on your trip to Saco, where heartwarming accommodations provide a peaceful escape, with nightly rates starting at $119.00. Discover the accessibility of Holiday Inn's online resources, including travel tips, destination guides, and hotel information.

At Holiday Inn Poplar Bluff an IHG Hotel, you’ll experience restful accommodations and the advantage of being close to Saco for day trips and adventures. Take the hassle out of your Saco stay with a hotel that prioritizes your needs—book today!

  Call (855) 234-2997 to book with an agent.
  40.0 miles from Saco, MO 63645

Starting at

$119.00

per night

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Comfort Inn Poplar Bluff North

2582 North Westwood Blvd Poplar Bluff, MO

Guests traveling to Saco will find Comfort Inn Poplar Bluff North a relaxing, budget-friendly option, with rooms beginning at $85.99, creating a welcoming atmosphere perfect for rest. Take a relaxing swim in our pristine pools, an ideal way to unwind after a day of activities or long meetings.

Step into relaxation at Comfort Inn Poplar Bluff North, a quiet retreat where you can explore Saco's excitement whenever you choose. Choose a hotel that adds value to your Saco journey—lock in your room now!

  Call (855) 234-2997 to book with an agent.
  40.3 miles from Saco, MO 63645

Starting at

$85.99

per night

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Current River Inn

602 Main St Van Buren, MO

Stay at Current River Inn on your trip to Saco, where comfortable accommodations create a restful escape, with inviting rates starting from just $93.99. Find comfort and style in our rooms that offer a range of amenities designed to enhance your stay.

Guests seeking a peaceful stay will love Current River Inn, positioned conveniently for easy access to Saco's attractions. Settle into Saco with a hotel that makes your experience unforgettable—lock in today!

  Call (855) 234-7135 to book with an agent.
  40.5 miles from Saco, MO 63645

Starting at

$93.99

per night

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Bullwinkles Rustic Lodge

399 Highway T Poplar Bluff, MO

Guests traveling to Saco will find affordable comfort at Bullwinkles Rustic Lodge, where calm rooms start at $89.99, creating a warm, inviting space ideal for unwinding. Stay in accommodations that prioritize practical comforts, with rooms that are efficiently designed for ease of use and relaxation.

Stay at Bullwinkles Rustic Lodge for a quiet escape, with the added benefit of having Saco's lively offerings just minutes away. Get ready for a Saco trip that’s as affordable as it is memorable—lock in today!

  Call (855) 239-4019 to book with an agent.
  42.1 miles from Saco, MO 63645

Starting at

$89.99

per night

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