The best deals on hotels when visiting San Antonio in Missouri.

From game day to getaway, save even more on every hotel stay.

Save up to 70% when booking as a group. Select 9+ rooms to get started.

Top 24 Hotels In San Antonio, Missouri 64443

Quality Suites St. Joseph

917 North Woodbine Rd St. Joseph, MO

At Quality Suites St. Joseph, travelers visiting San Antonio can unwind in warm-hearted comfort with rooms beginning at $106.99, creating a warm and welcoming environment. Find added comfort in accommodations that offer more amenities, creating a better experience at a great price.

A peaceful stay awaits guests at Quality Suites St. Joseph, with downtown San Antonio easily accessible by car for those looking to explore the city. Discover affordable comfort that’s perfect for exploring San Antonio—reserve your room today!

  Call (855) 234-2997 to book with an agent.
  5.8 miles from SAN Antonio, MO 64443

Starting at

$106.99

per night

Read Reviews View Amenities View All Rooms

Motel 6 Saint Joseph MO

4021 Frederick Ave St. Joseph, MO

For a intimate-feeling stay near San Antonio, Motel 6 Saint Joseph MO offers inviting accommodations with rooms beginning at $69.99, creating a warm and welcoming environment ideal for rest. Take advantage of the efficient space-saving designs in Motel 6 rooms, where everything you need is cleverly arranged for ease and comfort.

At Motel 6 Saint Joseph MO, guests can enjoy the peaceful surroundings of the hotel, while downtown San Antonio remains accessible by car for easy exploration. Enjoy reliable, budget-friendly accommodations for your San Antonio travels—book now!

  Call (855) 239-5277 to book with an agent.
  5.9 miles from SAN Antonio, MO 64443

Starting at

$69.99

per night

Read Reviews View Amenities View All Rooms

Stoney Creek Hotel St. Joseph

1201 North Woobine Rd St. Joseph, MO

With a blend of sophistication and comfort, Stoney Creek Hotel St. Joseph near San Antonio provides serene rooms crafted for relaxation, with rates beginning at $158.99. Enjoy a stay that exemplifies luxury, with rooms that are equipped with top-tier amenities and elegant furnishings.

At Stoney Creek Hotel St. Joseph, guests can appreciate the balance of being far enough for quiet, while still close enough to downtown San Antonio for a day of sightseeing. Find the ultimate relaxation in San Antonio with accommodations that make luxury feel effortless—secure now!

  Call (855) 233-0132 to book with an agent.
  6.0 miles from SAN Antonio, MO 64443

Starting at

$158.99

per night

Read Reviews View Amenities View All Rooms

Hampton Inn St. Joseph

3928 Frederick Ave St. Joseph, MO

With rooms starting at $165.99, Hampton Inn St. Joseph provides affordable accommodations for travelers visiting San Antonio, creating a welcoming and comfortable atmosphere. Find quiet and comfort in Hampton's soundproof rooms, where peace and privacy are prioritized for your relaxation.

A brief drive from Hampton Inn St. Joseph delivers guests into downtown San Antonio, where they can explore the city’s best attractions before returning to a peaceful stay. Stay effortlessly in San Antonio with accommodations that make relaxation simple—secure now!

  Call (855) 234-5074 to book with an agent.
  6.0 miles from SAN Antonio, MO 64443

Starting at

$165.99

per night

Read Reviews View Amenities View All Rooms

AmeriStay Inn

4502 South US Highway 169 St. Joseph, MO

Guests bound for San Antonio can enjoy inviting comfort at AmeriStay Inn, where serene rooms begin at $112.49, creating a warm and welcoming space ideal for relaxation. Relax in accommodations that offer extra amenities and comfort, designed for travelers seeking a bit more at a great value.

From AmeriStay Inn, guests can easily drive into downtown San Antonio, where they can explore the city’s attractions before returning to a quiet stay. Choose a hotel that complements your San Antonio plans with ease and affordability—secure now!

  Call (855) 234-2997 to book with an agent.
  6.6 miles from SAN Antonio, MO 64443

Starting at

$112.49

per night

Read Reviews View Amenities View All Rooms

Fairfield Inn & Suites by Marriott St. Joseph

4779 Tuscany Drive St. Joseph, MO

For an inviting and affordable stay, Fairfield Inn & Suites by Marriott St. Joseph offers budget-friendly rooms with rates starting at $189.99, creating a clean and comfortable space. Experience the festive spirit of Fairfield during the holidays, with special decorations, events, and treats to celebrate the season.

Guests staying at Fairfield Inn & Suites by Marriott St. Joseph can easily access downtown San Antonio, making it simple to balance city exploration with a more relaxed stay. Get ready for a relaxing San Antonio visit with affordable, well-appointed lodging—book now!

  Call (855) 234-7135 to book with an agent.
  6.9 miles from SAN Antonio, MO 64443

Starting at

$189.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express Hotel & Suites St. Joseph an IHG Hotel

3600 North Village Dr. St. Joseph, MO

Guests visiting San Antonio will find charming accommodations at Holiday Inn Express Hotel & Suites St. Joseph an IHG Hotel, with rooms beginning at $184.00, creating a clean, inviting environment perfect for rest. Relax with Holiday Inn Express's in-room yoga kits, allowing you to maintain your practice while on the road.

Guests staying at Holiday Inn Express Hotel & Suites St. Joseph an IHG Hotel will appreciate the peaceful surroundings, with downtown San Antonio still just a short drive from the hotel. Take the guesswork out of San Antonio travel with a hotel that prioritizes your comfort—lock in today!

  Call (855) 239-4019 to book with an agent.
  7.2 miles from SAN Antonio, MO 64443

Starting at

$184.00

per night

Read Reviews View Amenities View All Rooms

Econo Lodge Cameron

220 East Grand Ave Cameron, MO

With rooms beginning at $76.99, Econo Lodge Cameron offers alluring accommodations for guests traveling to San Antonio, creating a clean and welcoming space for relaxation. Make use of Econo Lodge's free parking, a convenient and cost-saving feature for guests traveling by car.

Enjoy a restful stay at Econo Lodge Cameron, where calm lodgings provide a peaceful atmosphere close to San Antonio's offerings. Stay affordably and experience the best of San Antonio with comfort—reserve now!

  Call (855) 233-7850 to book with an agent.
  23.8 miles from SAN Antonio, MO 64443

Starting at

$76.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Cameron

1710 North Walnut St Cameron, MO

Guests visiting San Antonio can relax in affordable comfort at Super 8 by Wyndham Cameron, where warm-hearted rooms begin at $125.99, providing a warm and inviting atmosphere. Grab a quick snack or essential item any time at Super 8’s well-equipped vending areas, conveniently accessible around the clock.

Guests at Super 8 by Wyndham Cameron can relax in a serene setting and still take advantage of San Antonio's top activities with ease. Plan ahead for a practical, budget-conscious San Antonio trip—reserve your stay now!

  Call (855) 235-6136 to book with an agent.
  23.9 miles from SAN Antonio, MO 64443

Starting at

$125.99

per night

Read Reviews View Amenities View All Rooms

SureStay Hotel by Best Western Cameron

2210 US Highway 36 Cameron, MO

With budget-conscious rooms beginning at $80.99, SureStay Hotel by Best Western Cameron provides restorative accommodations for travelers bound for San Antonio, creating a warm environment. Sleep soundly with Best Western's high-quality bedding and linens, designed for maximum comfort and relaxation.

Unwind in the calm environment of SureStay Hotel by Best Western Cameron, where city attractions are just a quick drive away for your convenience. Discover how great your San Antonio stay can be with thoughtful, cost-effective amenities—secure now!

  Call (855) 233-0132 to book with an agent.
  24.5 miles from SAN Antonio, MO 64443

Starting at

$80.99

per night

Read Reviews View Amenities View All Rooms

Quality Inn Cameron

1803 Comfort Ln Cameron, MO

With budget-conscious rooms beginning at $117.99, Quality Inn Cameron is an ideal choice for travelers to San Antonio, providing a warm and comfortable space for rest. Experience the ease of Quality Inn's valet parking service, providing convenient and secure vehicle storage for guests.

At Quality Inn Cameron, you can enjoy both restful accommodations and the easy access to San Antonio's vibrant downtown area. Step into an unforgettable San Antonio adventure with lodging that offers more for less—lock in today!

  Call (855) 234-2997 to book with an agent.
  24.8 miles from SAN Antonio, MO 64443

Starting at

$117.99

per night

Read Reviews View Amenities View All Rooms

Basswood Resort

15880 Interurban Rd Platte City, MO

Guests traveling to San Antonio will appreciate the cozy-like accommodations at Basswood Resort, with rooms starting at $93.99, creating a welcoming atmosphere. Experience enhanced comfort at an affordable price, with rooms that offer additional amenities for a more satisfying stay.

Relax and unwind at Basswood Resort, where spacious accommodations provide a peaceful environment while keeping San Antonio close by. Discover San Antonio from the comfort of a hotel that makes every dollar count—reserve today!

  Call (855) 235-0725 to book with an agent.
  27.5 miles from SAN Antonio, MO 64443

Starting at

$93.99

per night

Read Reviews View Amenities View All Rooms

Holiday Inn Express & Suites Atchison an IHG Hotel

401 Main St Atchison, KS

With rates from $179.99, Holiday Inn Express & Suites Atchison an IHG Hotel provides restorative accommodations for travelers visiting San Antonio, creating a comfortable and inviting space perfect for relaxation. Savor the convenience of Holiday Inn Express's grab-and-go breakfast options, perfect for early risers or guests on the move.

At Holiday Inn Express & Suites Atchison an IHG Hotel, spacious rooms and a serene setting create the perfect escape, just a short drive from San Antonio. Stay smart in San Antonio with a hotel that offers comfort and peace of mind—secure now!

  Call (855) 234-2997 to book with an agent.
  27.5 miles from SAN Antonio, MO 64443

Starting at

$179.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Atchison

509 South 9th St Atchison, KS

With budget-friendly rooms starting at $74.99, Super 8 by Wyndham Atchison is ideal for travelers to San Antonio, creating a clean, comfortable space perfect for relaxation. Enjoy great value without compromise at Super 8, offering budget-friendly rates alongside comfortable and clean accommodations.

At Super 8 by Wyndham Atchison, you’ll find the perfect balance of peaceful comfort and the convenience of being near San Antonio. Enjoy a cozy, cost-saving hotel for your San Antonio travels—book your stay today!

  Call (855) 234-2997 to book with an agent.
  28.0 miles from SAN Antonio, MO 64443

Starting at

$74.99

per night

Read Reviews View Amenities View All Rooms

Hotel Eastin Riverwalk

401 South 10th St Atchison, KS

With rooms starting at $59.53, Hotel Eastin Riverwalk offers budget-friendly accommodations for guests visiting San Antonio, creating a warm space ideal for a relaxing stay. Experience a stay that exceeds your expectations for value, with rooms providing all the necessary amenities without the fuss.

Relax in the peaceful surroundings of Hotel Eastin Riverwalk, a tranquil spot found just a short drive from San Antonio's lively attractions. Make your San Antonio trip relaxing and budget-friendly—secure your hotel stay now!

  Call (855) 235-6136 to book with an agent.
  28.0 miles from SAN Antonio, MO 64443

Starting at

$59.53

per night

Read Reviews View Amenities View All Rooms

Quality Inn Atchison

500 Highway 73 Atchison, KS

At Quality Inn Atchison, travelers bound for San Antonio can unwind in peaceful comfort with rooms starting at $148.65, creating a warm and welcoming space for relaxation. Make the most of your travel dollars at Quality Inn, where competitive rates offer great value without sacrificing quality.

At Quality Inn Atchison, you’ll be able to relax in a peaceful environment while keeping the sights of San Antonio easily accessible. Step into San Antonio comfort with accommodations that promise great value—book today!

  Call (855) 239-5277 to book with an agent.
  28.1 miles from SAN Antonio, MO 64443

Starting at

$148.65

per night

Read Reviews View Amenities View All Rooms

Travelodge by Wyndham Airport Platte City

504 Prairie View Rd Platte City, MO

Guests traveling to San Antonio will find budget-friendly comfort at Travelodge by Wyndham Airport Platte City, with peaceful rooms beginning at $58.99, creating a welcoming space perfect for unwinding. Enjoy the peace of mind with Travelodge's enhanced cleaning measures, focusing on guest room and common area cleanliness.

At Travelodge by Wyndham Airport Platte City, guests can experience a relaxing stay while enjoying easy access to San Antonio’s exciting attractions. Stay smart and comfortable on your San Antonio visit without breaking the bank—book now!

  Call (855) 233-0132 to book with an agent.
  28.3 miles from SAN Antonio, MO 64443

Starting at

$58.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Smithville / Kansas City

112 Cutting Dr Smithville, MO

For travelers bound for San Antonio, Super 8 by Wyndham Smithville / Kansas City offers inviting accommodations with rates beginning at $63.99, creating a clean, quiet setting for relaxation. Relax in Super 8's welcoming lobbies, perfect for reading, working, or planning your day's itinerary in comfort.

Super 8 by Wyndham Smithville / Kansas City offers the perfect mix of comfort and proximity, ensuring guests can relax while staying close to San Antonio. Plan your San Antonio trip with savings and extra comfort—reserve your room now!

  Call (855) 235-6136 to book with an agent.
  28.5 miles from SAN Antonio, MO 64443

Starting at

$63.99

per night

Read Reviews View Amenities View All Rooms

Suburban Studios Kansas City Airport North

1201 Branch Street Platte City, MO

For a peaceful and affordable stay, Suburban Studios Kansas City Airport North offers inviting accommodations with rates from $69.99, creating a clean and welcoming space perfect for relaxation. Relax in accommodations that provide a solid foundation for your travel needs, offering comfort and value without the frills.

Find your ideal retreat at Suburban Studios Kansas City Airport North, offering peaceful surroundings and effortless access to San Antonio’s many attractions. Choose a hotel that adds value to your San Antonio adventure—book your stay now!

  Call (855) 234-5074 to book with an agent.
  28.9 miles from SAN Antonio, MO 64443

Starting at

$69.99

per night

Read Reviews View Amenities View All Rooms

Ramada by Wyndham Platte City KCI Airport

2512 North Prairie View Road Platte City, MO

Choose Ramada by Wyndham Platte City KCI Airport for a welcoming stay when traveling to San Antonio, where quality rooms create a peaceful escape, with budget-friendly rates from $79.99. Enjoy a refreshing break with Ramada's afternoon refreshment service, featuring iced teas, lemonades, and light snacks.

Find your peaceful escape at Ramada by Wyndham Platte City KCI Airport, where guests enjoy a calm retreat and the option to explore San Antonio's vibrant life. Make the most of San Antonio with a hotel that understands your desire for comfort—book today!

  Call (855) 235-0725 to book with an agent.
  29.7 miles from SAN Antonio, MO 64443

Starting at

$79.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Platte City Kansas City Area Airport

2500 North Prairie View Rd Platte City, MO

Guests headed to San Antonio will find safe, budget-friendly comfort at Super 8 by Wyndham Platte City Kansas City Area Airport, where rooms begin at $67.99, creating a welcoming space perfect for relaxation. Settle into Super 8’s updated and refreshed rooms, designed to provide a contemporary and comfortable stay for all guests.

Relax and recharge at Super 8 by Wyndham Platte City Kansas City Area Airport, where serene surroundings provide a restful stay without losing the connection to San Antonio. Enjoy more of San Antonio with comfortable, cost-saving accommodations—book now!

  Call (855) 233-7850 to book with an agent.
  29.7 miles from SAN Antonio, MO 64443

Starting at

$67.99

per night

Read Reviews View Amenities View All Rooms

Kansas City Airport Marriott

775 Brasilia Ave Kansas City, MO

With welcoming accommodations, Kansas City Airport Marriott near San Antonio is an ideal retreat, where comfy rooms provide relaxation, with nightly rates starting at $149.99. Stay connected and productive in Marriott's versatile meeting spaces, equipped with cutting-edge technology for successful gatherings.

Unwind at Kansas City Airport Marriott, a tranquil retreat that provides easy access to the many attractions of San Antonio. Get the best of San Antonio with a hotel that combines luxury and affordability seamlessly—book today!

  Call (855) 234-5074 to book with an agent.
  32.1 miles from SAN Antonio, MO 64443

Starting at

$149.99

per night

Read Reviews View Amenities View All Rooms

Super 8 by Wyndham Kansas City Airport North

11900 North Plaza Circle Kansas City, MO

For a restful stay near San Antonio, Super 8 by Wyndham Kansas City Airport North offers affordable comfort with rooms beginning at $63.84, creating a clean, welcoming environment ideal for relaxation. Rest easy in Super 8's cozy rooms, designed with your comfort in mind and equipped with all the essentials for a good night's sleep.

At Super 8 by Wyndham Kansas City Airport North, guests can relax in a peaceful atmosphere while keeping the energy of San Antonio just a short drive away. Book a practical, inviting hotel for your San Antonio experience and enjoy more—secure now!

  Call (855) 236-8982 to book with an agent.
  32.3 miles from SAN Antonio, MO 64443

Starting at

$63.84

per night

Read Reviews View Amenities View All Rooms

Orangewood Inn & Suites Kansas City Airport

11828 North Plaza Circle Kansas City, MO

Discover a welcoming ambiance at Orangewood Inn & Suites Kansas City Airport near San Antonio, where refined accommodations provide comfort and quality, with budget-friendly rates from $123.99. Enjoy the sophistication of enhanced amenities in rooms designed for comfort and convenience, ensuring a pleasant stay.

At Orangewood Inn & Suites Kansas City Airport, guests are welcomed into a peaceful environment while keeping the sights of San Antonio just a drive away. Get ready to explore San Antonio in style with a hotel that makes every stay feel exclusive—lock in today!

  Call (855) 233-0132 to book with an agent.
  32.3 miles from SAN Antonio, MO 64443

Starting at

$123.99

per night

Read Reviews View Amenities View All Rooms