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Top 24 Hotels In San Antonio, Texas 78112

Holiday Inn Express & Suites San Antonio NW Medical Area an IHG Hotel

102 Spencer Lane San Antonio, TX

With budget-conscious rooms from $89.00, Holiday Inn Express & Suites San Antonio NW Medical Area an IHG Hotel provides comfy accommodations for guests bound for San Antonio, creating a clean, comfortable space. Stay productive with the well-lit work desks in each room at Holiday Inn Express, complete with ergonomic chairs.

Guests at Holiday Inn Express & Suites San Antonio NW Medical Area an IHG Hotel are just a short distance from San Antonio’s downtown, making it easy to walk or drive to the city’s top sights. Stay smart in San Antonio with a hotel that offers comfort and peace of mind—secure now!

  Call (855) 233-7850 to book with an agent.
  1.4 miles from SAN Antonio, TX 78112

Starting at

$89.00

per night

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La Quinta Inn by Wyndham IH 10 West San Antonio TX

5922 I 10 West San Antonio, TX

Guests headed to San Antonio will find friendly accommodations at La Quinta Inn by Wyndham IH 10 West San Antonio TX, where rooms begin at $53.99, creating a warm and welcoming environment ideal for rest. Enjoy the comfort of La Quinta's Bright Morning Bed®, promising a restful night's sleep and a bright start to your day.

With San Antonio’s downtown just a short distance away, La Quinta Inn by Wyndham IH 10 West San Antonio TX gives guests the perfect location for exploring the city without the noise of being in the center. Discover San Antonio with a hotel that offers unbeatable comfort at a great value—lock in now!

  Call (855) 234-2997 to book with an agent.
  1.4 miles from SAN Antonio, TX 78112

Starting at

$53.99

per night

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Days Inn by Wyndham Central San Antonio NW Medical Center

6023 I. H. 10 West San Antonio, TX

For a restful stay near San Antonio, Days Inn by Wyndham Central San Antonio NW Medical Center offers affordable comfort with rooms beginning at $59.40, creating a clean, welcoming environment ideal for relaxation. Experience the ease and flexibility of Days Inn's room configurations, accommodating solo travelers, couples, and families.

Guests at Days Inn by Wyndham Central San Antonio NW Medical Center can enjoy easy access to downtown San Antonio, where the city’s best sights and attractions are never far from reach. Make your San Antonio visit memorable and wallet-friendly—secure your hotel stay today!

  Call (855) 233-0132 to book with an agent.
  1.5 miles from SAN Antonio, TX 78112

Starting at

$59.40

per night

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Comfort Inn&Suites Near Medical Center

6039 IH 10 West San Antonio, TX

Guests visiting San Antonio will find inviting comfort at Comfort Inn&Suites Near Medical Center, where mellifluous rooms start at $61.99, creating a welcoming space perfect for relaxation. Rest easy knowing our enhanced cleaning protocols are in place to ensure a safe and comfortable environment for all guests.

At Comfort Inn&Suites Near Medical Center, you’re close enough to San Antonio’s center for a relaxed walk, but far enough to enjoy peace and quiet after a busy day. Make the most of your San Antonio experience with cozy, cost-effective hotel options—book now!

  Call (855) 234-2997 to book with an agent.
  1.5 miles from SAN Antonio, TX 78112

Starting at

$61.99

per night

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SpringHill Suites by Marriott San Antonio Medical Center / NW

3636 North Loop 410 San Antonio, TX

SpringHill Suites by Marriott San Antonio Medical Center / NW offers a relaxing option for travelers visiting San Antonio, with comfortable accommodations starting at a welcoming $124.99 per night. Appreciate the versatility of SpringHill Suites' accommodations, suitable for solo travelers, couples, families, and business guests alike.

SpringHill Suites by Marriott San Antonio Medical Center / NW provides the perfect balance of convenience and tranquility, offering guests easy access to downtown San Antonio without staying in the middle of the action. Rest easy in San Antonio knowing your accommodations deliver on quality and affordability—secure now!

  Call (855) 236-8982 to book with an agent.
  2.6 miles from SAN Antonio, TX 78112

Starting at

$124.99

per night

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OYO Inn & Suites Medical Center San Antonio

3782 North Loop 410 San Antonio, TX

Guests traveling to San Antonio will find budget-friendly comfort at OYO Inn & Suites Medical Center San Antonio, where reassuring rooms begin at $49.99, creating a clean, inviting space ideal for relaxation. Stay in a room that simplifies your travel, offering essential conveniences and a comfortable setting at a great value.

With downtown San Antonio just a short drive from OYO Inn & Suites Medical Center San Antonio, guests can visit the city’s most iconic spots while enjoying a quieter retreat. Enjoy an affordable stay that keeps comfort in mind while visiting San Antonio—secure now!

  Call (855) 239-5277 to book with an agent.
  2.6 miles from SAN Antonio, TX 78112

Starting at

$49.99

per night

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Rodeway Inn San Antonio Downtown

110 East Euclid Ave San Antonio, TX

At Rodeway Inn San Antonio Downtown, travelers bound for San Antonio can enjoy budget-conscious comfort with rooms starting at $105.99, creating a pleasant, inviting environment for rest. Find comfort in well-appointed rooms that offer everything you need for a worry-free and budget-friendly visit.

Rodeway Inn San Antonio Downtown offers a convenient location for those looking to visit downtown San Antonio, where the city’s top spots are just a quick drive away. Make your San Antonio visit comfortable and easy on your wallet—reserve now!

  Call (855) 236-8982 to book with an agent.
  2.7 miles from SAN Antonio, TX 78112

Starting at

$105.99

per night

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Motel 6 San Antonio TX Downtown Market Square

211 North Pecos La Trinidad San Antonio, TX

For a peaceful and budget-friendly stay, Motel 6 San Antonio TX Downtown Market Square offers inviting rooms with rates starting at $64.99, creating a clean, welcoming environment near San Antonio. Rely on the 24-hour security at Motel 6, ensuring a safe environment for you, your family, and your belongings.

Guests at Motel 6 San Antonio TX Downtown Market Square can enjoy quick access to downtown San Antonio, where the city’s top attractions are always within easy reach by car. Plan your San Antonio visit with enhanced comfort and affordability—reserve now!

  Call (855) 233-0132 to book with an agent.
  3.0 miles from SAN Antonio, TX 78112

Starting at

$64.99

per night

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San Antonio Marriott Northwest Medical Center

3233 North Loop 410 San Antonio, TX

With elevated comfort, San Antonio Marriott Northwest Medical Center near San Antonio provides a tranquil escape, where quality rooms start at an accessible rate of $149.99 per night. Be inspired by the artistic ambiance of Marriott's public areas, designed to foster creativity and connection among guests.

Guests staying at San Antonio Marriott Northwest Medical Center are never far from downtown San Antonio, where a short drive delivers them to the city’s most exciting attractions. Plan your ultimate San Antonio experience with accommodations that offer premium amenities—reserve now!

  Call (855) 234-2997 to book with an agent.
  3.0 miles from SAN Antonio, TX 78112

Starting at

$149.99

per night

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Super 8 by Wyndham San Antonio Pearl District / Downtown

1614 North Saint Marys Street San Antonio, TX

Guests traveling to San Antonio will find budget-friendly comfort at Super 8 by Wyndham San Antonio Pearl District / Downtown, with serene rooms beginning at $61.99, creating a welcoming space perfect for unwinding. Bring along your furry friends with confidence, thanks to Super 8’s welcoming pet policy that accommodates your beloved companions.

From Super 8 by Wyndham San Antonio Pearl District / Downtown, a quick drive delivers guests into downtown San Antonio, where the city’s most vibrant spots are just minutes away. Stay relaxed and keep your budget intact while visiting San Antonio—reserve now!

  Call (855) 233-7850 to book with an agent.
  3.1 miles from SAN Antonio, TX 78112

Starting at

$61.99

per night

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Hotel Indigo San Antonio Riverwalk an IHG Hotel

830 North Saint Marys St San Antonio, TX

Enjoy a charming escape at Hotel Indigo San Antonio Riverwalk an IHG Hotel as you explore San Antonio, where quality accommodations offer relaxation, with affordable rates starting at $139.99. Participate in Hotel Indigo’s local events and workshops, which provide an immersive introduction to the area's culture and community.

At Hotel Indigo San Antonio Riverwalk an IHG Hotel, a short drive delivers guests to downtown San Antonio, where the city’s most iconic destinations are within reach. Step into a San Antonio experience where your comfort is always the top priority—book today!

  Call (855) 234-7135 to book with an agent.
  3.2 miles from SAN Antonio, TX 78112

Starting at

$139.99

per night

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InterContinental San Antonio Riverwalk an IHG Hotel

111 East Pecan Street San Antonio, TX

Find the height of comfort at InterContinental San Antonio Riverwalk an IHG Hotel as you visit San Antonio, where every detail is designed to impress, with budget-friendly rates from $269.99. Appreciate the meticulous attention to detail at InterContinental, from luxurious linens to bespoke amenities.

At InterContinental San Antonio Riverwalk an IHG Hotel, guests are close enough to downtown San Antonio for a short drive, making it easy to explore the city’s best offerings. Enjoy a San Antonio getaway where every detail is crafted to perfection—reserve your accommodations now!

  Call (855) 236-8982 to book with an agent.
  3.2 miles from SAN Antonio, TX 78112

Starting at

$269.99

per night

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Thompson San Antonio Riverwalk by Hyatt

115 Lexington Avenue San Antonio, TX

Those visiting San Antonio will be impressed by Thompson San Antonio Riverwalk by Hyatt, where five-star accommodations make every moment unforgettable, with rates beginning at $238.99. Find unrivaled elegance in rooms designed for royalty, with plush furnishings, private spa facilities, and discreet service.

At Thompson San Antonio Riverwalk by Hyatt, guests are close enough to downtown San Antonio for a quick drive to the city’s most popular sights, while still enjoying a quieter atmosphere. Immerse yourself in San Antonio beauty with accommodations that elevate your visit—secure now!

  Call (855) 234-5074 to book with an agent.
  3.2 miles from SAN Antonio, TX 78112

Starting at

$238.99

per night

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Hotel Havana

1015 Navarro Street San Antonio, TX

Enjoy a welcoming stay at Hotel Havana as you explore San Antonio, where quality accommodations provide warmth, with inviting rates beginning at $188.99. Find an elevated level of comfort and style in rooms that feature luxurious amenities and meticulous attention to detail.

Hotel Havana provides easy access to downtown San Antonio, with the city’s most iconic sights just a short drive away. Stay in San Antonio with accommodations that make luxury feel attainable and effortless—lock in today!

  Call (855) 236-8982 to book with an agent.
  3.2 miles from SAN Antonio, TX 78112

Starting at

$188.99

per night

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Wyndham Garden San Antonio Riverwalk / Museum Reach

103 9th Street San Antonio, TX

With a blend of elegance and comfort, Wyndham Garden San Antonio Riverwalk / Museum Reach near San Antonio offers soothing rooms for a refined stay, with budget-friendly rates starting at $133.99. Relax in a setting that elevates your stay with luxurious amenities and a commitment to excellent service.

Wyndham Garden San Antonio Riverwalk / Museum Reach provides the ideal base for those wanting to explore San Antonio, where the downtown area is always just a short drive from the hotel. Experience San Antonio with a hotel that makes luxury feel personal and inviting—book today!

  Call (855) 234-2997 to book with an agent.
  3.3 miles from SAN Antonio, TX 78112

Starting at

$133.99

per night

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La Quinta Inn by Wyndham San Antonio Market Square

900 Dolorosa San Antonio, TX

For budget-conscious travelers to San Antonio, La Quinta Inn by Wyndham San Antonio Market Square offers delightful accommodations with rates from $88.99, creating a clean and comfortable space. Experience the warm, down-to-earth service at La Quinta, where hospitality is genuine and aimed at creating a home-like atmosphere.

At La Quinta Inn by Wyndham San Antonio Market Square, a quick drive delivers guests into the vibrant downtown area of San Antonio, where the city’s most iconic destinations are within reach. Take advantage of inviting accommodations perfect for your San Antonio visit—reserve now!

  Call (855) 234-2997 to book with an agent.
  3.3 miles from SAN Antonio, TX 78112

Starting at

$88.99

per night

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DoubleTree by Hilton San Antonio Downtown

502 West Cesar East Chavez San Antonio, TX

Those traveling to San Antonio will be captivated by DoubleTree by Hilton San Antonio Downtown, where plush accommodations offer refined relaxation, with nightly rates beginning at $90.99. Enjoy the convenience of DoubleTree by Hilton's shuttle services, offering easy access to local attractions and transportation hubs.

From DoubleTree by Hilton San Antonio Downtown, a short drive takes guests into downtown San Antonio, where the city’s most popular destinations are easily reachable. Experience San Antonio with a hotel that elevates your expectations and exceeds them—book today!

  Call (855) 233-7850 to book with an agent.
  3.3 miles from SAN Antonio, TX 78112

Starting at

$90.99

per night

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Holiday Inn Express San Antonio N Riverwalk Area an IHG Hotel

120 Camaron St. San Antonio, TX

With rooms starting at $94.49, Holiday Inn Express San Antonio N Riverwalk Area an IHG Hotel provides budget-friendly comfort for travelers bound for San Antonio, creating a clean, welcoming environment. Enjoy the simplicity of Holiday Inn Express's dining options, with a focus on fresh, tasty, and quick meals suitable for all travelers.

With downtown San Antonio only a short drive away, guests at Holiday Inn Express San Antonio N Riverwalk Area an IHG Hotel can explore the city’s best spots while enjoying a more peaceful location. Stay refreshed and relaxed in San Antonio with inviting, budget-friendly lodging—reserve now!

  Call (855) 235-0725 to book with an agent.
  3.3 miles from SAN Antonio, TX 78112

Starting at

$94.49

per night

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Ranch Motel

3101 Broadway San Antonio, TX

At Ranch Motel, travelers to San Antonio will find inviting rooms with rates from $160.99, creating a warm, welcoming space perfect for relaxation. Stay in accommodations that deliver a richer experience with added amenities, ensuring a satisfying and budget-friendly visit.

Ranch Motel provides the perfect location for those wanting to visit downtown San Antonio, where a brief drive brings them to the city’s most iconic sights. Step into San Antonio with confidence, knowing your hotel delivers more for less—reserve now!

  Call (855) 235-0725 to book with an agent.
  3.3 miles from SAN Antonio, TX 78112

Starting at

$160.99

per night

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Embassy Suites San Antonio Riverwalk Downtown

125 East Houston St San Antonio, TX

Find a charming retreat at Embassy Suites San Antonio Riverwalk Downtown as you explore San Antonio, where sophisticated accommodations offer comfort, with budget-friendly rates starting at $235.99. Discover local attractions with ease from Embassy Suites' convenient locations, situated near major sights and business centers.

From Embassy Suites San Antonio Riverwalk Downtown, a short drive delivers guests into downtown San Antonio, where the city’s most vibrant spots are easily accessible. Discover how San Antonio can feel like home with a hotel that makes comfort a priority—secure now!

  Call (855) 239-4019 to book with an agent.
  3.4 miles from SAN Antonio, TX 78112

Starting at

$235.99

per night

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Hotel Valencia Riverwalk

150 East Houston St San Antonio, TX

Relax in the extraordinary comfort of Hotel Valencia Riverwalk as you visit San Antonio, where refined accommodations promise serenity and grace, with rates beginning at $267.99. Find a haven of tranquility and luxury in rooms that combine opulent furnishings with cutting-edge amenities for a superior stay.

With downtown San Antonio only a brief drive away, guests at Hotel Valencia Riverwalk can easily explore the city’s top attractions while staying in a more peaceful location. Treat yourself to an extraordinary San Antonio escape with a hotel that prioritizes your comfort—book today!

  Call (855) 235-0725 to book with an agent.
  3.4 miles from SAN Antonio, TX 78112

Starting at

$267.99

per night

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Hampton Inn & Suites San Antonio Riverwalk

118 Soledad Street San Antonio, TX

Guests bound for San Antonio can enjoy inviting accommodations at Hampton Inn & Suites San Antonio Riverwalk, where rooms start at $134.99, creating a warm, welcoming environment for relaxation. Earn points with Hilton Honors when you stay at Hampton, and enjoy exclusive benefits that make travel more rewarding.

At Hampton Inn & Suites San Antonio Riverwalk, a quick drive brings guests into the heart of downtown San Antonio, where the city’s most exciting attractions are always close by. Maximize your San Antonio adventure with well-rounded, cost-effective accommodations—secure now!

  Call (855) 239-4019 to book with an agent.
  3.4 miles from SAN Antonio, TX 78112

Starting at

$134.99

per night

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AC Hotel by Marriott San Antonio Riverwalk

111 SOLEDAD STREET San Antonio, TX

With a blend of elegance and charm, AC Hotel by Marriott San Antonio Riverwalk near San Antonio provides quality accommodations, with budget-friendly nightly rates beginning at $159.99. Discover the sleek design and intuitive functionality of AC Hotels, where every detail is crafted for harmony and efficiency.

At AC Hotel by Marriott San Antonio Riverwalk, guests are never far from downtown San Antonio, where a short drive brings them to the city’s most exciting spots. Choose a hotel in San Antonio that turns every visit into an elegant escape—book today!

  Call (855) 239-5277 to book with an agent.
  3.4 miles from SAN Antonio, TX 78112

Starting at

$159.99

per night

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Home2 Suites by Hilton San Antonio Riverwalk TX

114 Soledad San Antonio, TX

Enjoy the warm ambiance of Home2 Suites by Hilton San Antonio Riverwalk TX when visiting San Antonio, where quality accommodations provide relaxation, with nightly rates beginning at $148.99. Stay entertained with Home2 Suites' Smart HDTVs in every suite, offering streaming capabilities and premium channels.

From Home2 Suites by Hilton San Antonio Riverwalk TX, a brief drive brings guests into downtown San Antonio, where the city’s most popular spots are easily accessible. Choose accommodations in San Antonio that transform your stay into something special—reserve now!

  Call (855) 239-4019 to book with an agent.
  3.4 miles from SAN Antonio, TX 78112

Starting at

$148.99

per night

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