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Top 24 Hotels In Santa Elena, Texas 78591

Quality Inn & Suites

4758 East Highway 83 Rio Grande City, TX

With rates beginning at $75.99, Quality Inn & Suites provides inviting accommodations for travelers visiting Santa Elena, creating a relaxed, welcoming space for relaxation. Stay productive with Quality Inn's business centers, complete with computers, printers, and high-speed internet access.

Guests seeking a peaceful stay will love Quality Inn & Suites, where calm surroundings are complemented by proximity to Santa Elena. Enjoy a seamless Santa Elena experience with well-rounded, budget-savvy lodging—book today!

  Call (855) 239-5277 to book with an agent.
  33.1 miles from Santa Elena, TX 78591

Starting at

$75.99

per night

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Holiday Inn Express & Suites Rio Grand an IHG Hotel

5274 East Highway 83 & Blanco Rd Rio Grande City, TX

At Holiday Inn Express & Suites Rio Grand an IHG Hotel, travelers to Santa Elena will find budget-friendly rooms with rates starting at $129.00, creating a clean, welcoming environment perfect for rest. Relax with blackout drapes in every room at Holiday Inn Express, ensuring a dark and quiet environment for a good night's sleep.

Relax at Holiday Inn Express & Suites Rio Grand an IHG Hotel, where guests can unwind in comfort and venture into Santa Elena at their leisure. Experience Santa Elena the way you deserve with budget-savvy, comfortable lodging—book now!

  Call (855) 234-2997 to book with an agent.
  33.2 miles from Santa Elena, TX 78591

Starting at

$129.00

per night

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Texas Inn&Suites at La Joya

612 East Express La Joya, TX

Guests headed to Santa Elena will enjoy the enveloping, budget-conscious accommodations at Texas Inn&Suites at La Joya, where rooms begin at $111.99, providing a welcoming environment for all. Relax in a space that's optimized for convenience, offering a practical approach to travel with all the necessary amenities.

At Texas Inn&Suites at La Joya, you can enjoy the best of both worlds—a peaceful setting and convenient access to Santa Elena's vibrant attractions. Stay relaxed and enjoy added comfort on your Santa Elena trip—book your room today!

  Call (855) 234-7135 to book with an agent.
  35.4 miles from Santa Elena, TX 78591

Starting at

$111.99

per night

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Econo Lodge Falfurrias Hwy 281

2116 Highway 281 South Falfurrias, TX

For guests headed to Santa Elena, Econo Lodge Falfurrias Hwy 281 provides inviting accommodations with rooms starting at $85.99, creating a warm and welcoming atmosphere for relaxation. Enjoy complimentary parking at Econo Lodge, adding another layer of value and convenience to your stay.

Relax in the calm environment of Econo Lodge Falfurrias Hwy 281, knowing that the many attractions of Santa Elena are never far away. Book now and make your Santa Elena trip comfortable and cost-effective—secure today!

  Call (855) 236-8982 to book with an agent.
  37.2 miles from Santa Elena, TX 78591

Starting at

$85.99

per night

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SureStay Hotel by Best Western Falfurrias

2299 South US Highway 281 Falfurrias, TX

For a intimate-feeling and affordable stay, SureStay Hotel by Best Western Falfurrias offers inviting rooms with rates beginning at $95.99, creating a comfortable space near Santa Elena. Maintain your health routine in Best Western's fully equipped fitness centers, designed to cater to all levels of exercise.

At SureStay Hotel by Best Western Falfurrias, guests can unwind in a serene setting, knowing that the lively atmosphere of Santa Elena is still accessible. Plan your Santa Elena adventure with extra comfort at a price you’ll love—book today!

  Call (855) 233-0132 to book with an agent.
  37.3 miles from Santa Elena, TX 78591

Starting at

$95.99

per night

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Texas Inn&Suites City Center at University Dr.

202 North 25th Avenue Edinburg, TX

Guests visiting Santa Elena can relax at Texas Inn&Suites City Center at University Dr., where budget-friendly rooms start at $68.72, creating a tucked away and inviting atmosphere perfect for relaxation. Enjoy standard amenities in rooms that offer a comfortable environment for a pleasant visit.

Discover a relaxing getaway at Texas Inn&Suites City Center at University Dr., where peaceful surroundings are paired with Santa Elena's nearby adventures. Book a value-focused hotel for your Santa Elena travels and make the most of your visit—secure now!

  Call (855) 235-0725 to book with an agent.
  38.0 miles from Santa Elena, TX 78591

Starting at

$68.72

per night

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Motel 6 Edinburg TX

1806 South Closner Blvd Edinburg, TX

Guests visiting Santa Elena can unwind at Motel 6 Edinburg TX, where affordable rooms start at $54.99, providing a warm, welcoming space perfect for relaxation. Check in and check out swiftly at Motel 6, designed to get you on your way without hassle.

At Motel 6 Edinburg TX, you’ll find the ideal base for rest and relaxation, with the vibrant life of Santa Elena nearby for exploration. Enjoy more of Santa Elena for less with budget-friendly, inviting hotel rooms—book now!

  Call (855) 235-0725 to book with an agent.
  38.4 miles from Santa Elena, TX 78591

Starting at

$54.99

per night

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Executive Inn

2006 South Closner Blvd Edinburg, TX

For budget-savvy travelers, Executive Inn offers pleasant comfort with rates beginning at $65.00, creating a warm and inviting atmosphere perfect for relaxation. Experience straightforward accommodations, where rooms are designed to meet the basic needs of guests looking for value and comfort.

Escape to the serenity of Executive Inn, a restful hideaway with Santa Elena's lively attractions only a short drive away. Stay relaxed and on budget while exploring Santa Elena with thoughtfully designed lodging—lock in today!

  Call (855) 233-0132 to book with an agent.
  38.4 miles from Santa Elena, TX 78591

Starting at

$65.00

per night

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Best Western Plus Edinburg Inn & Suites

2708 South US Highway 281 Edinburg, TX

For those headed to Santa Elena, Best Western Plus Edinburg Inn & Suites offers budget-friendly accommodations with rooms from $99.99, creating a clean, comfortable environment perfect for rest. Appreciate the enhanced bathroom features at Best Western Plus, including spacious vanities and high-quality toiletries.

Situated outside the busy hub, Best Western Plus Edinburg Inn & Suites lets you enjoy both the calm of your stay and the easy access to Santa Elena's attractions. Plan your Santa Elena visit with a hotel that offers comfort without compromise—secure today!

  Call (855) 239-5277 to book with an agent.
  38.7 miles from Santa Elena, TX 78591

Starting at

$99.99

per night

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HomeStay Inn & Suites Edinburg

2737 South Business Highway 281 Edinburg, TX

At HomeStay Inn & Suites Edinburg, travelers to Santa Elena will find affordable comfort with rooms beginning at $64.99, creating a clean and welcoming environment for unwinding. Experience a stay that offers a touch more in terms of comfort and amenities, providing a satisfying and economical visit.

Discover tranquility at HomeStay Inn & Suites Edinburg, a peaceful escape situated within a short distance of Santa Elena's best attractions. Get ready for an unforgettable Santa Elena visit with thoughtfully designed, budget-friendly lodging—lock in today!

  Call (855) 234-7135 to book with an agent.
  38.7 miles from Santa Elena, TX 78591

Starting at

$64.99

per night

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Holiday Inn Express & Suites Edinburg McAllen Area an IHG Hotel

3801 South Highway 281 Edinburg, TX

With rates starting at $162.28, Holiday Inn Express & Suites Edinburg McAllen Area an IHG Hotel is ideal for guests bound for Santa Elena, providing welcoming accommodations in a warm, inviting setting. Experience the family-friendly environment at Holiday Inn Express, with special accommodations and menus for children.

Guests seeking both rest and exploration will love Holiday Inn Express & Suites Edinburg McAllen Area an IHG Hotel, where peaceful lodgings are matched with easy access to Santa Elena. Find peace of mind during your Santa Elena adventure with lodging that prioritizes comfort—book today!

  Call (855) 239-5277 to book with an agent.
  39.2 miles from Santa Elena, TX 78591

Starting at

$162.28

per night

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Mainstay Suites Edinburg

4001 South US Highway 281 Edinburg, TX

Guests bound for Santa Elena will appreciate the budget-conscious comfort at Mainstay Suites Edinburg, with relaxed rooms starting at $69.99, creating a warm, inviting atmosphere. Relax with the comprehensive cable package provided in each suite at MainStay Suites, featuring a variety of entertainment options.

Nestled just outside Santa Elena, Mainstay Suites Edinburg provides the perfect balance of quiet accommodations and access to urban adventures. Unwind in Santa Elena with accommodations that blend affordability and relaxation—book today!

  Call (855) 236-8982 to book with an agent.
  39.3 miles from Santa Elena, TX 78591

Starting at

$69.99

per night

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Comfort Inn Edinburg South

4001 Closner Business 281 Edinburg, TX

Guests traveling to Santa Elena will find Comfort Inn Edinburg South a practical choice, with rooms beginning at $73.99, creating a clean and inviting environment ideal for relaxation. Choose Comfort Inn for an optimal travel experience, where convenience meets comfort at an affordable price.

Find your peaceful getaway at Comfort Inn Edinburg South, a restful haven where guests can unwind and still visit Santa Elena's lively offerings. Take advantage of extra features and affordability while exploring Santa Elena—lock in now!

  Call (855) 235-6136 to book with an agent.
  39.3 miles from Santa Elena, TX 78591

Starting at

$73.99

per night

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Tru by Hilton Edinburg

407 West Trenton Rd Edinburg, TX

At Tru by Hilton Edinburg, guests visiting Santa Elena can enjoy inviting accommodations with rates beginning at $114.99, creating a easygoing and welcoming space. Relax in Tru by Hilton’s efficiently designed rooms, where modern style and comfort are optimized for both business and leisure travelers.

Enjoy a relaxing stay at Tru by Hilton Edinburg, where a quiet environment allows you to unwind with the option to visit Santa Elena at your leisure. Enjoy peace of mind on your Santa Elena trip with accommodations designed for relaxation—book today!

  Call (855) 239-4019 to book with an agent.
  39.4 miles from Santa Elena, TX 78591

Starting at

$114.99

per night

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Home2 Suites by Hilton Edinburg TX

411 West TRENTON Edinburg, TX

Relax in the comfort of Home2 Suites by Hilton Edinburg TX near Santa Elena, where comfortable accommodations provide warmth and quality, with affordable nightly rates starting from $130.99. Choose Home2 Suites for its commitment to environmental sustainability, reflected in daily operations and guest amenities.

Enjoy a peaceful retreat at Home2 Suites by Hilton Edinburg TX, where the quiet atmosphere provides the perfect escape with Santa Elena nearby. Experience the best of Santa Elena with a hotel that delivers on both comfort and cost savings—secure now!

  Call (855) 235-0725 to book with an agent.
  39.4 miles from Santa Elena, TX 78591

Starting at

$130.99

per night

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Texas Inn&Suites Rio Grande Valley

1210 East Canton Rd Edinburg, TX

With rooms starting at $49.99, Texas Inn&Suites Rio Grande Valley offers inviting accommodations for travelers to Santa Elena, creating a serene and welcoming environment ideal for rest. Stay in a room that balances comfort and practicality, providing reliable amenities for an enjoyable visit.

Rest comfortably at Texas Inn&Suites Rio Grande Valley, enjoying the balance between a calm retreat and easy access to Santa Elena's highlights. Make your Santa Elena trip relaxing and budget-friendly—secure your hotel stay now!

  Call (855) 235-6136 to book with an agent.
  39.4 miles from Santa Elena, TX 78591

Starting at

$49.99

per night

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Garden Inn & Suite

1600 North Smith Ave Hebbronville, TX

With rates beginning at $86.99, Garden Inn & Suite is a practical choice for guests visiting Santa Elena, creating a clean and welcoming space perfect for unwinding. Stay in a room that balances comfort and value, offering practical amenities for a worry-free visit.

Escape the everyday rush at Garden Inn & Suite, where calm surroundings make for a refreshing stay with Santa Elena just a drive away. Make your Santa Elena adventure memorable and budget-wise—secure your hotel room now!

  Call (855) 234-5074 to book with an agent.
  39.5 miles from Santa Elena, TX 78591

Starting at

$86.99

per night

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SureStay Hotel by Best Western Mission

609 East Interstate Highway 2 Mission, TX

With rates from $35.99, SureStay Hotel by Best Western Mission provides inviting accommodations for guests bound for Santa Elena, creating a gentle and comfortable atmosphere for relaxation. Relax with a drink at Best Western’s rooftop bars, offering stunning views and a selection of craft cocktails and local beers.

Step into comfort at SureStay Hotel by Best Western Mission, a serene retreat with the convenience of Santa Elena's attractions just a short drive away. Treat yourself to a Santa Elena stay that blends convenience with budget-friendly rates—book now!

  Call (855) 236-8982 to book with an agent.
  39.6 miles from Santa Elena, TX 78591

Starting at

$35.99

per night

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Best Western Hebbronville Inn

37 East Highway 359 Hebbronville, TX

For budget-conscious travelers to Santa Elena, Best Western Hebbronville Inn offers intimate accommodations with rates from $139.99, creating a clean and comfortable space. Benefit from Best Western’s free shuttle services, offering convenient transport to local airports and major attractions.

Relax and recharge at Best Western Hebbronville Inn, a peaceful spot where you can rest comfortably and still explore Santa Elena's attractions. Indulge in a worry-free Santa Elena stay with budget-friendly, welcoming lodging—book now!

  Call (855) 235-6136 to book with an agent.
  39.8 miles from Santa Elena, TX 78591

Starting at

$139.99

per night

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Executive Inn Hebbronville

1310 North Smith St Hebbronville, TX

For budget-savvy travelers to Santa Elena, Executive Inn Hebbronville provides inviting accommodations with rooms from $75.99, creating a intimate-feeling, comfortable space perfect for rest. Enjoy reliable comfort in rooms that provide standard amenities, ensuring a pleasant stay at a great price.

Unwind in the tranquil setting of Executive Inn Hebbronville, a perfect spot to relax while keeping Santa Elena close enough for adventure. Enjoy Santa Elena with an inviting hotel that balances comfort and savings—book now!

  Call (855) 239-5277 to book with an agent.
  40.3 miles from Santa Elena, TX 78591

Starting at

$75.99

per night

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La Quinta Inn & Suites by Wyndham Mission at West McAllen

805 Travis Street Mission, TX

For an affordable and inviting stay, La Quinta Inn & Suites by Wyndham Mission at West McAllen offers warm-hearted rooms with rates from $89.99, creating a clean, comfortable atmosphere perfect for travelers. Indulge in La Quinta's weekend brunch options, featuring extended breakfast hours and special menu items.

Discover your serene getaway at La Quinta Inn & Suites by Wyndham Mission at West McAllen, where the peaceful atmosphere lets you recharge while keeping Santa Elena nearby. Step into Santa Elena comfort with inviting, cost-effective lodging—book your room now!

  Call (855) 236-8982 to book with an agent.
  40.4 miles from Santa Elena, TX 78591

Starting at

$89.99

per night

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Motel 6 Mission TX

1813 East Expressway 83 Mission, TX

For a hospitable stay near Santa Elena, Motel 6 Mission TX offers budget-friendly accommodations with rooms starting at $52.99, creating a clean and welcoming space ideal for rest. Enjoy the nostalgic feel of Motel 6, where decades of travelers' tales and memories add to the unique charm of each stay.

Unwind in the tranquil surroundings of Motel 6 Mission TX, where a restful stay is paired with convenient access to Santa Elena. Plan your Santa Elena getaway with ease and value-driven comfort—book today!

  Call (855) 235-6136 to book with an agent.
  40.5 miles from Santa Elena, TX 78591

Starting at

$52.99

per night

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Shary Inn&Suites

203 South Shary Rd Mission, TX

At Shary Inn&Suites, travelers to Santa Elena can enjoy inviting accommodations with rates starting at $61.99, providing a welcoming, comfortable environment. Stay in accommodations that provide a little extra, from enhanced comfort to additional amenities, all at a great value.

Escape to Shary Inn&Suites, where a quiet environment provides the perfect retreat, and Santa Elena's top spots are never too far. Enjoy a hassle-free Santa Elena adventure with extra perks at a great price—lock in today!

  Call (855) 235-0725 to book with an agent.
  40.6 miles from Santa Elena, TX 78591

Starting at

$61.99

per night

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Hampton Inn & Suites Mission

2505 Victoria Rd Mission, TX

For those headed to Santa Elena, Hampton Inn & Suites Mission offers budget-friendly comfort with rooms starting at $102.99, creating a clean, welcoming environment perfect for unwinding. Stay seamlessly connected with business-class Wi-Fi throughout Hampton properties, ensuring you’re never out of touch.

Guests can enjoy a peaceful stay at Hampton Inn & Suites Mission, while the lively streets of Santa Elena remain just a quick drive away. Unwind in Santa Elena with lodging that ensures you’re rested and refreshed—lock in today!

  Call (855) 235-0725 to book with an agent.
  40.7 miles from Santa Elena, TX 78591

Starting at

$102.99

per night

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