The best deals on hotels when visiting Serena in Louisiana.

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Top 24 Hotels In Serena, Louisiana 71343

Paragon Casino Resort

711 Paragon Place Marksville, LA

Find relaxation and comfort at Paragon Casino Resort on your trip to Serena, where quality rooms provide a peaceful retreat, with rates beginning at just $109.00. Experience a stay where luxury meets comfort, with rooms that are beautifully appointed and equipped with premium amenities.

Find your perfect getaway at Paragon Casino Resort, where a peaceful stay meets the ease of exploring Serena’s attractions. Take your Serena visit to new heights with accommodations that blend sophistication and value—book today!

  Call (855) 235-6136 to book with an agent.
  25.8 miles from Serena, LA 71343

Starting at

$109.00

per night

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Hampton Inn & Suites Marksville

6896 Highway 1 Mansura, LA

For those headed to Serena, Hampton Inn & Suites Marksville offers budget-friendly accommodations with rooms from $105.99, creating a clean, comfortable environment perfect for rest. Kickstart your day with Hampton's complimentary hot breakfast, a hearty and healthy way to start your morning.

Find your quiet retreat at Hampton Inn & Suites Marksville, where restful lodgings are paired with the convenience of being close to Serena. Make every moment in Serena count with a hotel that offers more for less—secure today!

  Call (855) 236-8982 to book with an agent.
  26.0 miles from Serena, LA 71343

Starting at

$105.99

per night

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Clarion Suites

100 Front St Vidalia, LA

At Clarion Suites, guests bound for Serena can unwind in inviting accommodations with rooms starting at $115.20, creating a warm, welcoming atmosphere. Relax in accommodations that provide more than just the essentials, offering added comfort and convenience for a pleasant stay.

Discover your peaceful sanctuary at Clarion Suites, where the calm of your stay is enhanced by the proximity to Serena's top spots. Plan your Serena trip with confidence, knowing your hotel delivers comfort and value—lock in today!

  Call (855) 234-5074 to book with an agent.
  27.6 miles from Serena, LA 71343

Starting at

$115.20

per night

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TownePlace Suites by Marriott Vidalia Riverfront

215 Front Street Vidalia, LA

For an inviting stay, TownePlace Suites by Marriott Vidalia Riverfront offers inviting rooms with rates starting at $169.99, creating a warm and welcoming space near Serena. TownePlace Suites serves as an ideal base for exploring local dining, shopping, and entertainment options.

Discover peace and relaxation at TownePlace Suites by Marriott Vidalia Riverfront, where a serene retreat is balanced with close proximity to Serena. Choose accommodations that make your Serena adventure easy and enjoyable—reserve now!

  Call (855) 239-5277 to book with an agent.
  27.6 miles from Serena, LA 71343

Starting at

$169.99

per night

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Hampton Inn & Suites Natchez

627 South Canal St Natchez, MS

With rates starting at $150.99, Hampton Inn & Suites Natchez is ideal for guests traveling to Serena, providing relaxed accommodations in a warm and inviting environment. Adjust your room’s climate to your preference with Hampton’s individual air conditioning units, ensuring comfort in any weather.

Discover relaxation at Hampton Inn & Suites Natchez, where quiet comfort meets the convenience of being close to Serena's vibrant offerings. Treat yourself to a memorable Serena trip with well-equipped, cost-friendly accommodations—reserve today!

  Call (855) 235-6136 to book with an agent.
  27.8 miles from Serena, LA 71343

Starting at

$150.99

per night

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Holiday Inn Express Hotel & Suites Natchez South an IHG Hotel

639 South Canal St Natchez, MS

At Holiday Inn Express Hotel & Suites Natchez South an IHG Hotel, guests visiting Serena will enjoy soothing accommodations with rates starting at $149.00, creating a clean and welcoming environment. Rely on the helpful staff at Holiday Inn Express, always ready to assist with recommendations, directions, and any other needs.

Discover the quiet charm of Holiday Inn Express Hotel & Suites Natchez South an IHG Hotel, a relaxing retreat that’s never too far from the bustling streets of Serena. Relax in Serena with a hotel that provides comfort and peace of mind—book today!

  Call (855) 233-7850 to book with an agent.
  27.9 miles from Serena, LA 71343

Starting at

$149.00

per night

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Magnolia Bluffs Best Western Signature Collection

645 South Canal Street Natchez, MS

Travelers exploring Serena will appreciate the inviting ambiance of Magnolia Bluffs Best Western Signature Collection, where easygoing rooms offer quality and warmth, with rates starting at $118.99. Appreciate the historical charm of certain Best Western hotels, which integrate local heritage and architecture into their design.

Find your perfect escape at Magnolia Bluffs Best Western Signature Collection, offering peaceful accommodations and easy access to Serena’s top attractions. Take in the magic of Serena with a hotel that turns your visit into a luxurious experience—secure now!

  Call (855) 239-4019 to book with an agent.
  27.9 miles from Serena, LA 71343

Starting at

$118.99

per night

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Natchez Grand Hotel & Suites on the River

111 South Broadway Street Natchez, MS

Relax in the tucked away surroundings of Natchez Grand Hotel & Suites on the River near Serena, where comfortable rooms create a warm atmosphere, with inviting rates beginning at $119.99 per night. Experience a blend of comfort and convenience in our rooms that provide a variety of amenities to enhance your visit.

Find the perfect balance of rest and fun at Natchez Grand Hotel & Suites on the River, situated in a calm area with Serena's sights within reach. Experience Serena in style with a hotel that offers luxury without the hefty price—lock in today!

  Call (855) 233-7850 to book with an agent.
  28.3 miles from Serena, LA 71343

Starting at

$119.99

per night

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Excellent Inn & Suites

43 Sgt Prentiss Drive Natchez, MS

For budget-conscious travelers headed to Serena, Excellent Inn & Suites offers comfortable rooms starting at $85.50, creating a clean and inviting atmosphere. Relax in a setting that offers more than the essentials, with added amenities to enhance your comfort and satisfaction.

Enjoy a tranquil stay at Excellent Inn & Suites, and venture into Serena whenever you're ready for more excitement. Discover a Serena stay that makes every moment worthwhile with practical, cost-saving lodging—lock in today!

  Call (855) 233-0132 to book with an agent.
  28.5 miles from Serena, LA 71343

Starting at

$85.50

per night

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Days Inn by Wyndham Natchez

109 Highway 61 S Natchez, MS

For those traveling to Serena, Days Inn by Wyndham Natchez offers comfy comfort with rooms beginning at $84.99, creating a clean and inviting atmosphere ideal for rest. Experience the joy of travel with Days Inn's family-friendly services, including accommodations that cater to the needs of younger guests.

For a peaceful stay with a short drive to the action, Days Inn by Wyndham Natchez provides the perfect escape just outside Serena. Book now for a value-packed, comfortable stay while visiting Serena—secure today!

  Call (855) 239-5277 to book with an agent.
  28.6 miles from Serena, LA 71343

Starting at

$84.99

per night

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Monmouth Historic Inns&Gardens

1358 John A. Quitman Blvd Natchez, MS

Relax in the inviting surroundings of Monmouth Historic Inns&Gardens as you explore Serena, where warm-hearted rooms offer a refined escape, with rates from an affordable $160.99. Experience a stay that is both majestic and intimate, with rooms that offer luxury amenities and personalized service.

At Monmouth Historic Inns&Gardens, guests can recharge in quiet surroundings while keeping Serena's best attractions close enough to explore. Make your Serena adventure truly memorable with a hotel that knows how to treat guests—reserve now!

  Call (855) 239-4019 to book with an agent.
  29.2 miles from Serena, LA 71343

Starting at

$160.99

per night

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FairBridge Inn Express Natchez

337 Devereaux Dr Natchez, MS

Guests traveling to Serena can unwind at FairBridge Inn Express Natchez, where budget-friendly rooms start at $46.99, creating a warm, inviting atmosphere ideal for rest. Relax in a setting that focuses on basic comforts, with rooms equipped with comfortable beds, a work area, and a clean bathroom.

Discover your serene getaway at FairBridge Inn Express Natchez, where the peaceful atmosphere lets you recharge while keeping Serena nearby. Take comfort in knowing your Serena trip is both cost-effective and enjoyable—book today!

  Call (855) 234-2997 to book with an agent.
  30.2 miles from Serena, LA 71343

Starting at

$46.99

per night

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Red Carpet Inn

271 D'Evereaux Drive Natchez, MS

For a comfortable and inviting stay, Red Carpet Inn offers budget-friendly rooms with rates from $68.00, creating a restorative environment ideal for travelers bound for Serena. Stay in accommodations that offer a bit more luxury and convenience, making your visit enjoyable and budget-friendly.

Find your serene escape at Red Carpet Inn, with the opportunity to explore Serena just a short drive from the hotel. Embrace your Serena adventure with lodging that keeps comfort within reach—reserve today!

  Call (855) 236-8982 to book with an agent.
  30.3 miles from Serena, LA 71343

Starting at

$68.00

per night

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Sleep Inn & Suites Pineville Alexandria

3411 US Highway 165 Pineville, LA

With affordable rooms starting at $63.99, Sleep Inn & Suites Pineville Alexandria provides gentle accommodations for travelers bound for Serena, creating a clean, inviting space. Savor Sleep Inn's fresh, hot coffee available in the lobby throughout the day, a perfect pick-me-up whenever you need it.

Settle into relaxation at Sleep Inn & Suites Pineville Alexandria, where the calm of your surroundings complements the nearby excitement of Serena. Plan a relaxing Serena getaway with accommodations that keep costs in check—book today!

  Call (855) 233-0132 to book with an agent.
  32.7 miles from Serena, LA 71343

Starting at

$63.99

per night

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OYO Hotel Pineville LA Hwy 165

11 Lord of Lords Ave Pineville, LA

Guests bound for Serena can enjoy affordable comfort at OYO Hotel Pineville LA Hwy 165, where rooms start at $57.86, creating a delightful, welcoming environment perfect for unwinding. Rest easy in clean, comfortable rooms that offer standard amenities, ensuring a worry-free stay at a great price.

At OYO Hotel Pineville LA Hwy 165, the peaceful atmosphere offers guests a restful stay while keeping the attractions of Serena close by. Make your Serena adventure affordable and stress-free—lock in your room today!

  Call (855) 234-5074 to book with an agent.
  32.9 miles from Serena, LA 71343

Starting at

$57.86

per night

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Holiday Inn Express Pineville Alexandria Area an IHG Hotel

2820 Monroe Highway Pineville, LA

For a serene and affordable stay near Serena, Holiday Inn Express Pineville Alexandria Area an IHG Hotel offers comfortable accommodations with rates beginning at $99.00, providing a warm environment. Experience the family-friendly environment at Holiday Inn Express, with special accommodations and menus for children.

Find your perfect escape at Holiday Inn Express Pineville Alexandria Area an IHG Hotel, offering peaceful accommodations and easy access to Serena’s top attractions. Unwind in Serena with budget-friendly accommodations that don’t skimp on comfort—book now!

  Call (855) 239-5277 to book with an agent.
  33.2 miles from Serena, LA 71343

Starting at

$99.00

per night

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Country Inn & Suites by Radisson Pineville LA

2727 Monroe Hwy Pineville, LA

With budget-conscious rooms beginning at $76.99, Country Inn & Suites by Radisson Pineville LA is a practical choice for travelers to Serena, providing a warm and inviting space ideal for rest. Experience the convenience of vending machines at Country Inn & Suites, offering snacks and drinks for a quick pick-me-up.

Find your ideal balance at Country Inn & Suites by Radisson Pineville LA, where guests can experience the tranquility of the surroundings while Serena stays close by. Take a break in Serena with a hotel that understands the value of your time and money—book today!

  Call (855) 233-0132 to book with an agent.
  33.5 miles from Serena, LA 71343

Starting at

$76.99

per night

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Hotel Bentley

200 DeSoto St Alexandria, LA

Embrace an extraordinary experience at Hotel Bentley as you journey to Serena, where thoughtfully curated accommodations promise luxury, with rates from $117.99. Relax in rooms that set a new standard for luxury, with bespoke furnishings and comprehensive, personalized services.

At Hotel Bentley, you’ll find the ideal combination of calm surroundings and proximity to all that Serena has to offer. Experience Serena with a hotel that elevates your expectations and exceeds them—book today!

  Call (855) 233-0132 to book with an agent.
  35.4 miles from Serena, LA 71343

Starting at

$117.99

per night

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Holiday Inn Alexandria Downtown an IHG Hotel

701 4th St. Alexandria, LA

Stay affordably at Holiday Inn Alexandria Downtown an IHG Hotel when traveling to Serena, with restful accommodations crafted to provide comfort, all beginning at $129.00 per night for an inviting experience. Discover the accessibility of Holiday Inn's online resources, including travel tips, destination guides, and hotel information.

Guests seeking calm surroundings will enjoy Holiday Inn Alexandria Downtown an IHG Hotel, a peaceful haven with easy access to Serena's top destinations. Enjoy every moment of your Serena adventure with a hotel that prioritizes quality and affordability—lock in today!

  Call (855) 239-4019 to book with an agent.
  35.5 miles from Serena, LA 71343

Starting at

$129.00

per night

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Home2 Suites by Hilton Alexandria

3800 Alexandria Mall Dr Alexandria, LA

Enjoy a peaceful atmosphere at Home2 Suites by Hilton Alexandria as you journey to Serena, where restful accommodations provide comfort, with budget-friendly rates starting at $152.99. Stay refreshed with Home2 Suites' saline swimming pools, offering a health-conscious way to relax and unwind.

Find your peaceful escape at Home2 Suites by Hilton Alexandria, nestled within easy driving distance of Serena’s top attractions. Unwind in Serena with a hotel that brings added convenience to your journey—reserve now!

  Call (855) 233-7850 to book with an agent.
  36.7 miles from Serena, LA 71343

Starting at

$152.99

per night

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Super 8 by Wyndham Alexandria LA

2001 North Bolton Ave Alexandria, LA

Guests bound for Serena can enjoy affordable comfort at Super 8 by Wyndham Alexandria LA, with rooms starting at $79.00, providing a welcoming and relaxing environment. Enjoy smooth arrivals and departures with Super 8's streamlined check-in and check-out process, designed for your convenience.

Relax and unwind at Super 8 by Wyndham Alexandria LA, where calm surroundings are paired with quick access to Serena's bustling attractions. Plan your Serena getaway with ease and value-driven comfort—book today!

  Call (855) 233-0132 to book with an agent.
  36.9 miles from Serena, LA 71343

Starting at

$79.00

per night

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Four Points by Sheraton Alexandria

2301 North Macarthur Dr Alexandria, LA

Uncover a intimate-feeling escape at Four Points by Sheraton Alexandria on your journey to Serena, where quality rooms provide relaxation, with inviting rates beginning at $99.99. Experience the community vibe of Sheraton’s weekly social hours, a chance to mingle with guests and enjoy local flavors.

Whether you're here for business or pleasure, Four Points by Sheraton Alexandria provides a peaceful setting that keeps Serena within easy reach. Plan your Serena travels with a hotel that makes elegance accessible—reserve now!

  Call (855) 236-8982 to book with an agent.
  37.0 miles from Serena, LA 71343

Starting at

$99.99

per night

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TownePlace Suites by Marriott Alexandria

3810 Alexandria Mall Drive Alexandria, LA

At TownePlace Suites by Marriott Alexandria, guests traveling to Serena will find inviting accommodations with rooms starting at $219.99, creating a appealing, welcoming environment perfect for rest. Benefit from TownePlace Suites' Marriott Bonvoy™ membership, offering rewards and perks that enhance your travel experience.

At TownePlace Suites by Marriott Alexandria, you'll find a peaceful retreat with the added benefit of being close to Serena for exploration. Step into Serena comfort with accommodations that promise great value—book today!

  Call (855) 235-6136 to book with an agent.
  37.1 miles from Serena, LA 71343

Starting at

$219.99

per night

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Courtyard by Marriott Alexandria

3830 Alexandria Mall Dr Alexandria, LA

Experience quality and comfort at Courtyard by Marriott Alexandria as you explore Serena, where restful rooms create a welcoming atmosphere, with rates starting from $144.99. Grab a quick and healthy meal with Courtyard's convenient grab-and-go options, perfect for busy days when you're on the move.

Find calm and convenience at Courtyard by Marriott Alexandria, offering a tranquil setting and quick access to Serena's popular attractions. Step into Serena with a hotel that makes every detail of your stay seamless—reserve your room now!

  Call (855) 233-7850 to book with an agent.
  37.1 miles from Serena, LA 71343

Starting at

$144.99

per night

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