Top 24 Hotels In Southhampton, Missouri 63109

Find a hospitable getaway at Forest Park Hotel by MDR as you visit Southhampton, where inviting rooms offer comfort and quality, with rates starting from an accessible $89.99. Find comfort and convenience in rooms designed with your needs in mind, offering a higher standard of amenities.

At Forest Park Hotel by MDR, guests are always close enough to downtown Southhampton for a quick drive, making it simple to explore the city’s top spots. Take your Southhampton experience to the next level with a hotel that has everything you need—book today!

With rates starting at $101.99, Red Roof Inn PLUS+ St. Louis Forest Park / Hampton Ave is ideal for guests bound for Southhampton, providing pleasant accommodations in a warm, inviting setting. Unwind with Red Roof Inn's expanded cable TV offerings, providing entertainment and relaxation after a day of travel or meetings.

Red Roof Inn PLUS+ St. Louis Forest Park / Hampton Ave provides the perfect mix of convenience and calm, with downtown Southhampton only a brief drive away for easy access to the city’s best spots. Stay comfortably and affordably in Southhampton with amenities designed for your needs—secure now!

Guests bound for Southhampton can unwind at Hampton Inn & Suites St. Louis at Forest Park, where restful rooms start at $157.45, creating a warm and inviting environment perfect for relaxation. Stay updated with Hampton’s digital displays, providing current information on weather, local attractions, and hotel services.

Hampton Inn & Suites St. Louis at Forest Park is ideally positioned for those wanting to explore Southhampton, where downtown is always just a short drive away for easy access. Rest easy during your Southhampton adventure with accommodations that make sense—lock in today!

Stay at SpringHill Suites St. Louis Brentwood for a peaceful visit to Southhampton, where comfortable accommodations offer quality and comfort, with nightly rates starting at $169.99. Outdoor patios and terraces at SpringHill Suites offer peaceful retreats to enjoy the fresh air and scenic views.

SpringHill Suites St. Louis Brentwood provides the perfect mix of convenience and calm, with downtown Southhampton only a brief drive away for easy access to the city’s best spots. Enjoy every moment of your Southhampton trip with accommodations that go the extra mile—lock in today!

Stay comfortably at TownePlace Suites by Marriott Brentwood on your journey to Southhampton, where intimate-feeling accommodations and welcoming service create a restful retreat, all from $154.99. TownePlace Suites by Marriott offers spacious suites that are perfect for families and extended stays.

Guests staying at TownePlace Suites by Marriott Brentwood can enjoy easy access to downtown Southhampton, where a brief drive takes them to the city’s top destinations. Relax and enjoy your Southhampton adventure with accommodations that make every day special—book today!

Enjoy a restful stay at Courtyard by Marriott St. Louis Brentwood on your trip to Southhampton, where comfortable accommodations provide relaxation, with room rates beginning at $149.99 per night. Choose Courtyard by Marriott for your next stay, where modern amenities and thoughtful service ensure a perfectly balanced travel experience.

Courtyard by Marriott St. Louis Brentwood is ideally positioned for those wanting to explore Southhampton, where downtown is always just a short drive away for easy access. Uncover the joy of Southhampton travel with a hotel that provides unmatched convenience—lock in today!

Choose Home2 Suites by Hilton St. Louis / Forest Park as you explore Southhampton, where inviting rooms create a welcoming retreat, with budget-friendly rates starting from $164.99. Participate in Home2 Suites' guest recycling program, part of the brand's commitment to environmental responsibility.

From Home2 Suites by Hilton St. Louis / Forest Park, guests can quickly reach downtown Southhampton, where the city’s most popular destinations are just minutes away. Find the perfect blend of comfort and affordability for your Southhampton adventure—book today!

Step into a world of luxury at DoubleTree by Hilton St. Louis Forest Park as you explore Southhampton, where quality accommodations create comfort and elegance, with rates starting at $151.99. Dine outdoors at DoubleTree by Hilton, where meals come with a view in beautifully appointed al fresco settings.

Guests at DoubleTree by Hilton St. Louis Forest Park will appreciate the short drive to downtown Southhampton, where the city’s most exciting destinations are always within easy reach. Make your Southhampton adventure as special as possible with a hotel that understands luxury—reserve now!

Unwind in the restful environment of Aloft St. Louis Cortex when visiting Southhampton, where inviting rooms offer warmth, with nightly rates starting at an accessible $149.99. Dive into Aloft's tech-savvy approach, featuring room controls via app for a personalized stay tailored to your preferences.

With downtown Southhampton only a short drive from Aloft St. Louis Cortex, guests can easily visit the city’s most vibrant areas while staying in a quieter setting. Make your Southhampton travels relaxing and budget-smart with well-rounded lodging—reserve now!

At MainStay Suites St. Louis Galleria, travelers to Southhampton will find intimate, budget-friendly accommodations with rates from $131.99, creating a welcoming environment perfect for rest. Enjoy the added convenience of complimentary grocery delivery service at MainStay Suites, bringing fresh ingredients right to your door.

With downtown Southhampton just a short drive away, guests at MainStay Suites St. Louis Galleria can easily explore the city’s most vibrant spots while staying in a more peaceful setting. Stay affordably and comfortably on your Southhampton adventure with well-equipped lodging—lock in today!

Those visiting Southhampton will be enchanted by The Royal Sonesta Chase Park Plaza St. Louis, where upscale details merge seamlessly with comfort, with nightly rates beginning at $295.00. Relax in Sonesta’s garden terraces, beautifully maintained spaces ideal for a quiet afternoon or an evening under the stars.

Guests at The Royal Sonesta Chase Park Plaza St. Louis are never far from downtown Southhampton, where a brief drive delivers them to the city’s most iconic spots. Find your perfect escape in Southhampton with a hotel that defines sophistication—reserve now!

At Holiday Inn Express St. Louis Central West End an IHG Hotel, travelers to Southhampton can unwind in gentle comfort with rooms beginning at $134.99, creating a warm and inviting space ideal for relaxation. Enjoy peace of mind with Holiday Inn Express's express check-out service, streamlining your departure for a quick and easy exit.

With a brief drive into downtown Southhampton, guests at Holiday Inn Express St. Louis Central West End an IHG Hotel can explore the city’s most iconic spots while returning to a peaceful retreat. Relax in Southhampton with a hotel that delivers convenience and savings—secure your room today!

Those visiting Southhampton will find tranquility at AC Hotel St. Louis Central West End, where appealing accommodations offer luxury, with rates starting at an affordable $157.99. Appreciate the curated art and design elements at AC Hotels, reflecting the brand's emphasis on beauty, style, and cultural relevance.

From AC Hotel St. Louis Central West End, a short drive brings guests into downtown Southhampton, where the city’s most popular attractions are always within easy reach. Find out how exceptional Southhampton can be with a hotel that delivers in every way—lock in today!

With rates beginning at $189.99, The Charles F. Knight Center provides budget-friendly accommodations for travelers visiting Southhampton, creating a warm and inviting environment. Find straightforward comfort in rooms that offer a clean and simple setup, ideal for travelers seeking practicality and value.

With easy access to downtown Southhampton, guests at The Charles F. Knight Center can quickly explore the city’s most vibrant areas while enjoying a more peaceful retreat. Take comfort in knowing your Southhampton stay is both cozy and budget-friendly—reserve today!

Choose Homewood Suites by Hilton St. Louis Galleria for your trip to Southhampton, where quality accommodations offer comfort and affordability, with comforting rooms beginning at $151.99 per night. Stay connected with complimentary high-speed Wi-Fi at Homewood Suites, making it easy to work or stay in touch while you're away.

With downtown Southhampton only a brief drive from Homewood Suites by Hilton St. Louis Galleria, guests can explore the city’s top destinations while staying in a quieter area. Plan your Southhampton travels with a hotel that understands your need for comfort and convenience—reserve now!

With budget-friendly rooms starting at $99.99, The West End provides practical accommodations for travelers bound for Southhampton, creating a warm and inviting atmosphere. Enjoy a comfortable retreat in rooms that offer the basic necessities for a relaxing and budget-conscious visit.

The West End offers the perfect balance of proximity and peace, with downtown Southhampton only a short drive from the hotel. Stay affordably and experience the best of Southhampton with comfort—reserve now!

Stay comfortably at Element St. Louis Midtown on your trip to Southhampton, where enveloping rooms create a welcoming atmosphere, with rates beginning at an inviting $179.99. Stay connected with Element's complimentary high-speed Wi-Fi, designed for convenience whether you're working or unwinding.

Guests at Element St. Louis Midtown can easily reach downtown Southhampton with just a short drive, offering convenient access to the city’s top attractions. Make your Southhampton visit unforgettable with a hotel that provides unparalleled comfort—lock in today!

Indulge in pure luxury at The Ritz Carlton St. Louis near Southhampton, where each room is a sanctuary of elegance, with inviting nightly rates starting from $629.99. Experience the grandeur of the Ritz-Carlton Ballroom, ideal for lavish weddings and galas, featuring state-of-the-art facilities and elegant decor.

With downtown Southhampton only a short drive away, guests at The Ritz Carlton St. Louis can explore the city’s top attractions while enjoying a quieter setting. Celebrate your Southhampton escape with accommodations that offer a sanctuary of luxury—lock in today!

With exquisite details, Moonrise Hotel near Southhampton promises an elevated stay, where inviting accommodations come at budget-friendly rates starting from $252.99. Stay in rooms designed for the luxury traveler, featuring sumptuous bedding, artisanal amenities, and comprehensive concierge services.

With downtown Southhampton just a brief drive from Moonrise Hotel, guests can enjoy the city’s most vibrant spots while staying in a more relaxed area. Take in the elegance of Southhampton with a hotel that delivers unmatched comfort and style—secure now!

Step into a premier experience at Le Méridien St. Louis Clayton near Southhampton, where refined accommodations ensure a serene retreat, with budget-friendly rates starting at $169.99. Experience the enchantment of Le Méridien's evening dessert hours, a sweet conclusion to the day with exquisite creations.

Le Méridien St. Louis Clayton offers the perfect location for guests who want to explore Southhampton, where the downtown area is just a brief drive away. Relax in Southhampton with a hotel that turns your visit into a world-class experience—lock in today!

Enjoy a snug stay at AC Hotel St. Louis Clayton as you visit Southhampton, where restful rooms offer comfort and warmth, with rates beginning at just $184.99 per night. Discover the sleek design and intuitive functionality of AC Hotels, where every detail is crafted for harmony and efficiency.

With downtown Southhampton only a short drive away, guests at AC Hotel St. Louis Clayton can explore the city’s best sights while enjoying a quieter retreat. Step into a world of comfort and convenience on your Southhampton adventure—book now!

Experience an inviting stay at Clayton Plaza Hotel & Extended Stay on your journey to Southhampton, where refined accommodations provide relaxation, with budget-friendly rates from $120.99. Appreciate the flexibility of pet-friendly accommodations at Extended Stay America, where your furry friends are welcome to join your extended visit.

With downtown Southhampton just a short drive from Clayton Plaza Hotel & Extended Stay, guests can easily access the city’s top destinations while enjoying a more peaceful stay. Unwind in Southhampton with accommodations that transform your stay into a dream—secure now!

Relax in style at Seven Gables St. Louis West a Tribute Portfolio Hotel near Southhampton, where quality rooms provide a warm retreat, with budget-friendly rates beginning at $249.99 per night. Relax with Tribute Portfolio's comprehensive wellness options, including spa services and yoga classes, catering to your every need.

Guests staying at Seven Gables St. Louis West a Tribute Portfolio Hotel are never far from downtown Southhampton, where a short drive brings them to the city’s most exciting spots. Make your Southhampton visit unforgettable with accommodations that never compromise on quality—reserve now!

With a perfect blend of elegance and comfort, River City Casino & Hotel near Southhampton provides quality rooms for a luxurious stay, with rates starting at just $191.99. Stay in accommodations that are the epitome of elegance, offering rooms that are thoughtfully designed and richly furnished.

River City Casino & Hotel is perfectly situated for guests wanting to visit downtown Southhampton, where the city’s best attractions are just a quick drive away. Find out how luxurious Southhampton can be with a hotel that perfects every detail—lock in today!