Top 24 Hotels In St. Matthews, South Carolina 29135

With budget-friendly rooms from $179.99, SpringHill Suites by Marriott Orangeburg provides cushy accommodations for travelers bound for St. Matthews, creating a warm, welcoming space. Discover local attractions with ease, thanks to SpringHill Suites' knowledgeable staff and central locations.

At SpringHill Suites by Marriott Orangeburg, visitors can unwind in the peaceful surroundings of the hotel, with downtown St. Matthews still within easy reach for a day of exploration. Enjoy St. Matthews to the fullest with accommodations that won’t strain your wallet—reserve today!

At Sleep Inn Orangeburg, guests bound for St. Matthews will find inviting rooms with rates beginning at $130.99, creating a warm and comfortable space perfect for relaxation. Stay connected with Sleep Inn's free high-speed Wi-Fi, perfect for both leisure and business travelers.

From Sleep Inn Orangeburg, a convenient drive takes guests to downtown St. Matthews, where they can explore the city’s highlights before returning to the hotel’s calm setting. Embrace a worry-free St. Matthews adventure with practical, inviting lodging—reserve your room now!

Guests headed to St. Matthews will find welcoming comfort at Holiday Inn Express & Suites Orangeburg, where inviting rooms start at $154.00, creating a welcoming environment ideal for relaxation. Relax in Holiday Inn Express's indoor heated pool, a perfect year-round relaxation spot for guests of all ages.

Guests at Holiday Inn Express & Suites Orangeburg can enjoy the quiet surroundings, while downtown St. Matthews is still within easy reach for a day of sightseeing. Step into St. Matthews comfort with a hotel that prioritizes both convenience and savings—book today!

Guests traveling to St. Matthews will appreciate the calm comfort at Tru by Hilton Orangeburg, where budget-friendly rooms start at $158.99, creating a warm and inviting space for rest. Experience the attentive and personalized customer service at Tru by Hilton, where guest satisfaction is a top priority.

Guests staying at Tru by Hilton Orangeburg will love how close they are to downtown St. Matthews, while still enjoying the peaceful surroundings of the hotel. Enjoy your St. Matthews visit with a hotel that combines convenience and value perfectly—lock in today!

At Days Inn by Wyndham Orangeburg, guests visiting St. Matthews can enjoy alluring, affordable rooms starting at $93.99, creating a clean and inviting environment for a peaceful stay. Relax in the assurance that Days Inn meets rigorous standards for cleanliness and guest satisfaction, providing a worry-free stay.

The calm atmosphere at Days Inn by Wyndham Orangeburg offers guests a restful stay, with downtown St. Matthews just a drive away for easy access to the city’s highlights. Lock in enhanced comfort for your St. Matthews adventure—reserve your hotel now!

Guests traveling to St. Matthews can unwind in inviting accommodations at Suburban Studios, where inviting rooms start at $75.99, creating a clean, comfortable space. Enjoy standard amenities in rooms that provide a comfortable environment for a budget-friendly stay.

Guests at Suburban Studios will appreciate the balance of city access and a quieter, more peaceful environment, with downtown St. Matthews still within reach. Enjoy an affordable St. Matthews experience with extra perks—book your hotel now!

For a welcoming and affordable stay, Quality Inn & Suites offers budget-friendly rooms with rates beginning at $113.99, creating a clean and comfortable space. Experience the convenience of on-site parking at Quality Inn, with ample space and secure facilities for your vehicle.

Guests staying at Quality Inn & Suites will love the convenience of being close to downtown St. Matthews, while enjoying the peaceful atmosphere of the hotel. Make memories in St. Matthews while staying at a hotel that caters to your comfort—reserve now!

For a appealing and affordable stay, Travelodge by Wyndham Orangeburg offers inviting accommodations with rooms from $94.05, creating a welcoming space perfect for travelers bound for St. Matthews. Start each morning at Travelodge with a smile, thanks to the friendly staff and warm, inviting atmosphere throughout the hotel.

From Travelodge by Wyndham Orangeburg, a quick drive brings guests into downtown St. Matthews, where they can explore the city’s best spots and return to a quiet retreat. Book a comfortable, budget-friendly stay for your St. Matthews visit today!

For an affordable, relaxing stay, Super 8 by Wyndham Orangeburg offers plush accommodations with rooms from $80.00, creating a clean and inviting environment perfect for rest. Keep hunger at bay with Super 8's vending machines, stocked with snacks and beverages for that late-night craving or quick snack.

From Super 8 by Wyndham Orangeburg, the drive into downtown St. Matthews is straightforward, allowing guests to explore the city’s top destinations while returning to a peaceful setting afterward. Make your St. Matthews experience affordable and relaxing—lock in your hotel today!

For a comfortable and budget-friendly experience, Baymont by Wyndham Orangeburg North offers warm rooms with rates starting at $96.99, creating a warm environment perfect for rest. Enjoy the family-oriented amenities at Baymont by Wyndham, including cribs, high chairs, and family-friendly activities.

Guests staying at Baymont by Wyndham Orangeburg North can appreciate the calm surroundings, while downtown St. Matthews remains easily accessible by car for all their sightseeing needs. Rest assured knowing your St. Matthews trip will be cozy and budget-conscious—book your room today!

With affordable rooms beginning at $171.99, Comfort Inn & Suites provides budget-conscious comfort for guests bound for St. Matthews, creating a welcoming atmosphere. Rest assured knowing that your safety and comfort are prioritized with top-notch security and cleanliness standards.

With a simple drive into downtown St. Matthews, guests at Comfort Inn & Suites can balance city exploration with the peaceful surroundings of the hotel. Make memories in St. Matthews while staying at a hotel that caters to your comfort—reserve now!

At Fairfield Inn by Marriott Orangeburg, travelers visiting St. Matthews can enjoy inviting accommodations with rooms starting at $199.99, creating a warm, welcoming environment for rest. Welcome to Fairfield by Marriott, where guests are treated to the warm hospitality and simple comforts that make travel a joy.

At Fairfield Inn by Marriott Orangeburg, visitors can enjoy the calm of staying outside the city center, while downtown St. Matthews remains within reach for easy exploration. Enjoy St. Matthews in comfort and without financial stress—book your room today!

With rates beginning at $60.99, Orangeburg Inn & Suites is a convenient choice for travelers to St. Matthews, offering budget-friendly accommodations in a welcoming setting. Relax in accommodations that offer practical comfort and standard amenities, making your stay both pleasant and economical.

Guests staying at Orangeburg Inn & Suites will enjoy the balance of easy city access and the peaceful retreat offered by the hotel. Make your St. Matthews adventure budget-friendly and comfortable—reserve now!

Guests headed to St. Matthews will enjoy the mellifluous, budget-conscious accommodations at Days Inn by Wyndham Orangeburg South, where rooms begin at $88.99, providing a welcoming environment for all. Explore vibrant neighborhoods with convenient access to dining and shopping, thanks to our strategically located properties.

Enjoy a peaceful atmosphere at Days Inn by Wyndham Orangeburg South, where guests can relax knowing that downtown St. Matthews remains close enough for exploration. Make your St. Matthews travels relaxing and budget-smart—reserve your hotel today!

At Quality Inn & Suites, guests traveling to St. Matthews can enjoy budget-friendly rooms starting at $75.99, creating a warm and welcoming space perfect for unwinding. Trust in Quality Inn's dedication to cleanliness, providing a safe and welcoming environment for every guest.

Relax away from the crowds at Quality Inn & Suites, but keep the excitement of St. Matthews close enough for easy exploration. Relax and enjoy St. Matthews knowing your hotel is both cozy and budget-conscious—lock in today!

Guests bound for St. Matthews will appreciate the soothing comfort at Comfort Inn & Suites Santee, with budget-friendly rooms beginning at $135.99, creating a warm and inviting space. Park securely and conveniently at no extra cost, a valued feature that adds peace of mind to your stay.

Discover relaxation at Comfort Inn & Suites Santee, where guests can experience a quiet stay while keeping the vibrant life of St. Matthews nearby. Relax and enjoy St. Matthews knowing your hotel is both cozy and budget-conscious—lock in today!

Experience the comfort of Holiday Inn Santee an IHG Hotel as you explore St. Matthews, where restful accommodations provide warmth and relaxation, with rates beginning at $155.00. Access snacks and essentials at any time with Holiday Inn’s 24/7 marketplaces, perfect for late-night cravings or forgotten items.

Escape to Holiday Inn Santee an IHG Hotel for a quiet retreat, where guests can relax in comfort while keeping St. Matthews's attractions nearby. Relax in St. Matthews at a hotel that ensures every moment is pure comfort—secure now!

With rooms beginning at $81.99, Red Roof Inn Santee is a convenient choice for travelers to St. Matthews, providing budget-conscious comfort in a warm, inviting setting. Stay connected throughout your travels with Red Roof Inn’s complimentary high-speed Wi-Fi, perfect for both business and leisure guests.

Discover the perfect escape at Red Roof Inn Santee, where the peaceful ambiance is matched by the convenience of St. Matthews's nearby attractions. Make your St. Matthews visit cozy and cost-effective—secure your hotel stay now!

With affordable rooms from $92.99, Baymont by Wyndham Santee provides inviting comfort for travelers to St. Matthews, creating a clean, welcoming space perfect for relaxation. Enjoy the added privacy and comfort of Baymont by Wyndham’s adjoining rooms, ideal for families or groups traveling together.

Settle into relaxation at Baymont by Wyndham Santee, where guests can recharge in comfort with St. Matthews always within convenient reach. Stay in St. Matthews with a hotel that caters to your needs and budget—secure your room now!

Guests bound for St. Matthews can enjoy inviting accommodations at Tru by Hilton Santee, where rooms start at $154.99, creating a warm, welcoming environment for relaxation. Enjoy the complimentary 'Top It' breakfast bar at Tru by Hilton, featuring a wide selection of sweet and savory toppings for your morning meal.

Positioned just outside St. Matthews, Tru by Hilton Santee ensures guests can recharge while keeping urban adventures close by. Stay worry-free in St. Matthews with a hotel that offers all the essentials at a great price—lock in now!

For those bound for St. Matthews, Best Western Plus Santee Inn offers serene, budget-friendly accommodations with rates from $125.99, creating a comfortable space perfect for relaxation. Relax with the nightly turn-down service available at Best Western Plus, preparing your room each evening for a restful night's sleep.

Discover the quiet charm of Best Western Plus Santee Inn, a relaxing retreat that’s never too far from the bustling streets of St. Matthews. Experience a well-rounded St. Matthews stay with amenities that keep you comfortable—reserve now!

With rates beginning at $152.99, Hampton Inn Santee I-95 provides budget-friendly comfort for guests bound for St. Matthews, creating a calm and inviting environment. Sleep well in Hampton's clean and fresh Hampton beds®, designed for a good night's sleep with plush duvets and soft pillows.

Find your tranquil retreat at Hampton Inn Santee I-95, offering restful accommodations with the convenience of St. Matthews nearby. Experience St. Matthews with peace of mind, knowing your hotel delivers value—secure now!

With rates beginning at $159.99, Fairfield Inn & Suites by Marriott Santee is a practical choice for guests visiting St. Matthews, providing a sheltered and inviting space ideal for relaxation. Take a refreshing break in Fairfield’s tea lounges, offering a selection of herbal and traditional teas throughout the day.

At Fairfield Inn & Suites by Marriott Santee, you’ll find both relaxation and the ease of reaching St. Matthews's bustling attractions in no time. Explore St. Matthews worry-free with accommodations that prioritize comfort—secure today!

With rooms starting at $72.99, Econo Lodge provides affordable, inviting accommodations for guests traveling to St. Matthews, creating a secure and welcoming space. Rest assured knowing Econo Lodge is part of the respected Choice Hotels group, ensuring standards of quality and reliability.

Relax at Econo Lodge, where spacious rooms and proximity to St. Matthews create an inviting atmosphere for guests. Choose a cost-effective, welcoming hotel for your St. Matthews visit—book now!