Top 24 Hotels In Wilkie, Missouri 63301

Choose The Green Tree Inn near Wilkie for a delightful balance of quality and affordability, where inviting rooms provide comfort at a starting rate of $198.99 per night. Enjoy a stay that prioritizes comfort and convenience, with rooms equipped to provide a range of modern amenities.

From The Green Tree Inn, a brief drive delivers guests to downtown Wilkie, where the city’s best attractions are easily reachable. Stay comfortably in Wilkie with a hotel that takes care of every detail—book today!

Experience a delightful retreat at Holiday Inn Express Hotel&Suites St. Charles an IHG Hotel as you explore Wilkie, where restful accommodations await at a starting rate of $144.95 per night. Indulge in the comfort of Holiday Inn Express's plush duvet covers and soft linens, ensuring a cozy and restful sleep experience.

From Holiday Inn Express Hotel&Suites St. Charles an IHG Hotel, a convenient drive into downtown Wilkie allows guests to enjoy the city’s highlights while returning to a quiet, restful stay. Take advantage of a Wilkie stay where luxury and budget-friendly rates coexist—lock in today!

At Sleep Inn & Suites, guests bound for Wilkie will enjoy budget-friendly comfort with rooms starting at $74.99, creating a warm and welcoming atmosphere. Take advantage of Sleep Inn's laundry facilities, making it easy to keep your travel wardrobe fresh and ready for anything.

From Sleep Inn & Suites, the drive into downtown Wilkie is straightforward, allowing guests to explore the city’s top destinations while returning to a peaceful setting afterward. Stay worry-free in Wilkie with a hotel that offers all the essentials at a great price—lock in now!

With budget-conscious rooms beginning at $80.99, Best Western St. Louis Airport North Hotel & Suites is an ideal choice for travelers to Wilkie, providing a warm and comfortable space for rest. Choose from Best Western's diverse portfolio, including upscale Best Western Premier® and cozy Best Western Plus® locations.

From Best Western St. Louis Airport North Hotel & Suites, a brief drive takes guests into downtown Wilkie, where they can explore the city’s top spots and return to a quieter stay afterward. Maximize your Wilkie experience with a hotel that makes your stay unforgettable—reserve today!

Guests traveling to Wilkie will appreciate the inviting accommodations at La Quinta Inn by Wyndham St. Louis Hazelwood Airport North, where charming rooms start at $62.99, creating a warm, welcoming space. Savor a peaceful night's sleep on La Quinta's Bright Morning Bed®, designed for comfort and support.

With downtown Wilkie a convenient drive away, guests at La Quinta Inn by Wyndham St. Louis Hazelwood Airport North can explore the city’s top destinations while enjoying the serenity of the hotel afterward. Settle into Wilkie with a hotel that balances convenience and cost savings—lock in now!

Guests visiting Wilkie can enjoy inviting accommodations at Comfort Inn & Suites St. Louis Hazelwood, with budget-friendly rooms starting at $90.99, creating a clean, welcoming environment. Take part in our loyalty program, reaping benefits like accelerated bookings and exclusive member rates.

Staying at Comfort Inn & Suites St. Louis Hazelwood allows guests to retreat to a serene location, with downtown Wilkie still within easy reach for a day’s adventures. Enjoy more of Wilkie with a practical hotel designed for your convenience—reserve now!

For an affordable stay, Motel 6 Hazelwood MO offers alluring accommodations with rates beginning at $62.99, creating a clean, comfortable environment near Wilkie. Enjoy the simple, no-frills approach of Motel 6, focusing on what's most important: a good night's sleep at a great price.

Guests staying at Motel 6 Hazelwood MO will appreciate the balance of a quiet stay, while downtown Wilkie is just a convenient drive away for easy access. Book an inviting, budget-friendly hotel for your Wilkie travels and relax—reserve now!

Guests visiting Wilkie will appreciate the delightful, affordable comfort at HomeTowne Studios by Red Roof St. Louis Airport / N Lindbergh, where rooms start at $53.99, providing a clean and inviting space perfect for relaxation. Experience dependable comfort in rooms that offer standard amenities, ensuring a pleasant and budget-conscious stay.

A peaceful stay awaits guests at HomeTowne Studios by Red Roof St. Louis Airport / N Lindbergh, with downtown Wilkie easily accessible by car for those looking to explore the city. Make your Wilkie travels relaxing and budget-smart—reserve your hotel today!

With budget-conscious rooms beginning at $56.99, Quality Inn Florissant St. Louis is an ideal choice for travelers to Wilkie, providing a warm and comfortable space for rest. Enjoy peace of mind with Quality Inn's comprehensive fire safety and evacuation plans, ensuring guest safety in any emergency.

The tranquil setting of Quality Inn Florissant St. Louis allows guests to unwind, while the vibrancy of downtown Wilkie is still a convenient drive away for a day of exploration. Stay refreshed and on budget in Wilkie with thoughtfully designed accommodations—secure today!

With rooms starting at $119.00, Sonesta Simply Suites St. Louis Earth City offers inviting accommodations for travelers visiting Wilkie, creating a clean and welcoming space for rest. Stay connected and productive with Sonesta’s complimentary high-speed Wi-Fi and state-of-the-art business facilities.

Guests staying at Sonesta Simply Suites St. Louis Earth City will love how easy it is to drive into downtown Wilkie, explore the city’s top spots, and return to a peaceful retreat. Book a welcoming, cost-effective hotel for your Wilkie trip and save big—secure now!

For a comfortable and inviting stay, Country Inn & Suites by Radisson St. Charles MO offers inviting rooms with rates beginning at $88.99, creating a clean and comfortable space near Wilkie. Relax with in-room amenities at Country Inn & Suites, including a mini-fridge, microwave, and coffee maker for your convenience.

Guests at Country Inn & Suites by Radisson St. Charles MO will appreciate the balance of city access and a quieter, more peaceful environment, with downtown Wilkie still within reach. Make the most of your Wilkie experience with cozy, cost-effective hotel options—book now!

For an affordable and restful stay, The Lodge Hotel&Banquets offers inviting accommodations with rooms starting at $61.99, creating a warm, welcoming space ideal for relaxation. Experience a stay that combines comfort with value, offering rooms that provide essential amenities for a budget-friendly rate.

At The Lodge Hotel&Banquets, guests can relax in a quieter environment, with downtown Wilkie still within easy reach for a day of exploring. Enjoy a practical, inviting stay perfect for your Wilkie travels—lock in today!

With refined accommodations and a welcoming ambiance, Holiday Inn St. Louis Arpt West Earth City an IHG Hotel is an ideal retreat near Wilkie, with rates beginning at an accessible $107.86. Welcome to Holiday Inn, where a commitment to warm service and a memorable stay awaits every guest.

At Holiday Inn St. Louis Arpt West Earth City an IHG Hotel, visitors can unwind in the peaceful surroundings, knowing that downtown Wilkie remains accessible by car for easy city exploration. Unwind in Wilkie with a hotel that offers the perfect blend of luxury and value—secure now!

Relax in the sumptuous atmosphere of Ameristar Casino Resort&Spa as you travel to Wilkie, where every accommodation is a testament to elegance, with rates starting at $177.65. Experience bespoke luxury in accommodations where every detail is tailored to enhance your comfort and satisfaction.

Guests at Ameristar Casino Resort&Spa will appreciate the tranquil atmosphere, with downtown Wilkie just a drive away for easy access to the city’s top destinations. Discover how exceptional Wilkie can be with accommodations that exceed every expectation—secure now!

Unwind at Best Western Plus The Charles Hotel near Wilkie, where comfortable rooms create a welcoming escape from the road, with inviting rates starting at $92.99 per night. Experience the attention to detail at Best Western Plus, where every aspect of your stay is designed for comfort and satisfaction.

With downtown Wilkie a drive from Best Western Plus The Charles Hotel, guests can explore the city’s best spots while returning to a more peaceful setting afterward. Step into your Wilkie adventure with a hotel that makes your stay both luxurious and affordable—secure now!

For a calm and affordable stay near Wilkie, Americas Best Value Inn & Suites St. Louis St. Charles Inn offers comfortable accommodations with rates beginning at $79.99, providing a warm environment. Experience the warmth of Americas Best Value Inn's hospitality, where the friendly staff make your satisfaction their priority.

Guests staying at Americas Best Value Inn & Suites St. Louis St. Charles Inn will love the convenience of being close to downtown Wilkie, while enjoying the peaceful atmosphere of the hotel. Enjoy Wilkie in comfort and without financial stress—book your room today!

At Hampton Inn & Suites St. Charles Old Town Area, guests bound for Wilkie can enjoy enchanting accommodations with rates starting at $118.15, creating a clean, inviting space perfect for relaxation. Admire the contemporary decor in Hampton’s guest rooms, combining style and functionality for a pleasant and efficient stay.

From Hampton Inn & Suites St. Charles Old Town Area, the drive to downtown Wilkie is quick and convenient, allowing guests to explore the city’s attractions while returning to a quieter retreat. Make the most of your Wilkie visit with a hotel that delivers exceptional value—reserve now!

At Comfort Suites St. Charles St. Louis, guests bound for Wilkie can enjoy inviting rooms with rates starting at $91.99, creating a clean and comfortable space ideal for relaxation. Relax in spacious suites at Comfort Suites, designed with separate areas for sleeping, working, and relaxing.

From Comfort Suites St. Charles St. Louis, a brief drive takes guests into downtown Wilkie, where they can explore the city’s top spots and return to a quieter stay afterward. Choose a hotel that takes your Wilkie experience to the next level—book now!

With budget-friendly rooms beginning at $82.99, Extended Stay America Select Suites St. Louis Earth City provides inviting comfort for travelers bound for Wilkie, creating a warm and welcoming space. Relax with Extended Stay America’s in-room climate control, ensuring your comfort no matter the weather outside.

At Extended Stay America Select Suites St. Louis Earth City, guests can unwind in a serene environment while having downtown Wilkie just a drive away for easy city access. Enjoy your Wilkie visit with a hotel that combines convenience and value perfectly—lock in today!

Explore a relaxing retreat at SpringHill Suites by Marriott St. Louis Airport / Earth City near Wilkie, where inviting rooms create a welcoming ambiance, with affordable nightly rates from $129.99. Appreciate the versatility of SpringHill Suites' accommodations, suitable for solo travelers, couples, families, and business guests alike.

The relaxing surroundings at SpringHill Suites by Marriott St. Louis Airport / Earth City allow guests to unwind, while downtown Wilkie is still just a drive away for easy access to the city’s main spots. Maximize your Wilkie experience with a hotel that keeps you pampered and stress-free—secure now!

Explore a warm retreat at Courtyard St. Louis Airport / Earth City near Wilkie, where inviting accommodations offer quality and relaxation, with nightly rates starting from $111.20. Relax with the peace of mind provided by Courtyard's secure parking options, ensuring your vehicle is safe during your stay.

From Courtyard St. Louis Airport / Earth City, the drive into downtown Wilkie is simple, allowing guests to enjoy the city’s top spots while staying in a more relaxed environment. Stay affordably in Wilkie with a hotel that offers luxury without the price tag—lock in today!

At Baymont by Wyndham St. Charles, travelers bound for Wilkie will find serene rooms with rates beginning at $79.99, creating a warm and welcoming space ideal for relaxation. Enjoy the added convenience of Baymont by Wyndham’s express checkout service, allowing for a quick and easy departure.

The relaxing surroundings at Baymont by Wyndham St. Charles offer guests a quiet retreat, with downtown Wilkie just a convenient drive away for easy access. Step into Wilkie comfort with inviting, cost-effective lodging—book your room now!

Relax in style at Embassy Suites by Hilton St. Louis St. Charles on your journey to Wilkie, where quality rooms offer comfort and elegance, with inviting nightly rates beginning at $138.67. Indulge in the spaciousness of Embassy Suites' accommodations, offering separate bedrooms and living areas for privacy and relaxation.

From Embassy Suites by Hilton St. Louis St. Charles, guests can easily drive into downtown Wilkie, where they can experience the city’s highlights and return to a serene stay. Take advantage of a Wilkie stay where every detail is designed for your pleasure—reserve now!

Explore a warm and homely stay at Elimwood Hotel a Ramada by Wyndham on your trip to Wilkie, where quality accommodations provide comfort, with inviting rates from $91.99. Enjoy the intimacy of Ramada's private dining experiences, where meals are served in secluded settings for a romantic or exclusive atmosphere.

The relaxing atmosphere at Elimwood Hotel a Ramada by Wyndham is balanced by the convenience of downtown Wilkie, which is still just a drive away for easy access. Get ready for an extraordinary Wilkie visit with a hotel that caters to your every need—lock in today!