Top 24 Hotels In Winona, South Carolina 29506

For those visiting Winona, Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 an IHG Hotel offers budget-friendly accommodations with rooms from $149.00, creating a comfortable, inviting atmosphere. Enjoy the privacy and convenience of ensuite bathrooms in every room, featuring modern fixtures and complimentary toiletries.

From Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 an IHG Hotel, a simple drive brings guests into downtown Winona, where they can explore the city’s highlights and return to a quieter stay. Choose a hotel that makes your Winona experience delightful and budget-friendly—book now!

Experience a tucked away getaway at Hyatt Place Florence Downtown near Winona, where comfortable accommodations create a welcoming stay, with budget-friendly rates from $179.00. Feel welcomed and at ease in the vibrant atmosphere of Hyatt Place, where thoughtful amenities and stylish decor ensure a pleasant stay.

At Hyatt Place Florence Downtown, visitors can enjoy the balance of being near downtown Winona while staying in a quieter, more peaceful location. Unwind in Winona with a hotel that makes relaxation feel effortless and affordable—reserve now!

Find a delightful escape at Hotel Florence Tapestry Collection by Hilton when visiting Winona, where quality rooms create a relaxing stay, with rates starting at an accessible $163.99. Embrace the individuality of each Tapestry Collection hotel, where no two properties are the same, yet all promise a remarkable stay.

Guests at Hotel Florence Tapestry Collection by Hilton will enjoy the quiet surroundings, while downtown Winona remains within reach for a day of sightseeing. Get ready for a Winona trip filled with thoughtful amenities and great savings—reserve now!

For an affordable and restful stay, Holiday Inn Express & Suites Latta an IHG Hotel offers cushy comfort with rates starting at $189.00, creating a warm and welcoming environment ideal for relaxation. Appreciate the cleanliness and safety protocols at Holiday Inn Express, ensuring a worry-free and healthy stay for all guests.

Enjoy a calming retreat at Holiday Inn Express & Suites Latta an IHG Hotel, where quiet surroundings and Winona's energy are just a drive apart. Experience Winona comfortably and within budget with inviting accommodations—book today!

Guests bound for Winona will appreciate the reassuring comfort at Best Western Executive Inn, with budget-friendly rooms beginning at $111.99, creating a warm and inviting space. Order in with Best Western's room service, enjoying the convenience of delicious meals delivered directly to your door.

At Best Western Executive Inn, guests can unwind in quiet surroundings, with the added convenience of downtown Winona being just a drive away. Make your Winona travels both comfortable and cost-efficient—reserve now!

For an inviting stay, Baymont Inn & Suites Florence by Wyndham offers snug rooms with rates starting at $43.99, creating a warm and welcoming space near Winona. Relax in the intimate and friendly environment of Baymont by Wyndham, designed to make every traveler feel right at home.

Guests at Baymont Inn & Suites Florence by Wyndham will love the peaceful setting, while downtown Winona is still close enough for easy exploration. Take comfort in knowing your Winona stay is both budget-wise and enjoyable—reserve today!

Guests headed to Winona will find budget-friendly comfort at Best Western Inn, where intimate-feeling rooms begin at $79.99, creating a welcoming atmosphere perfect for relaxation. Experience Best Western’s attention to detail, from impeccably maintained facilities to personalized guest services.

At Best Western Inn, visitors can enjoy the quiet retreat, while still being close enough to downtown Winona for a day of sightseeing. Get more out of your Winona adventure with accommodations that save you money—secure now!

Guests bound for Winona can enjoy affordable comfort at Super 8 by Wyndham Florence, with rooms beginning at $68.99, creating a pleasant and inviting atmosphere perfect for relaxation. Discover the ease of travel with Super 8's prime locations, conveniently close to major roads and local attractions.

Unwind at Super 8 by Wyndham Florence, where peaceful surroundings set the tone for a restful stay, and downtown Winona remains a short drive away. Enjoy a simple yet comfortable hotel for your Winona travels—book your room today!

Guests traveling to Winona will appreciate the calm accommodations at Clarion Inn & Suites, with rooms starting at $47.99, creating a welcoming atmosphere. Appreciate the seasonal decorations at Clarion Inn, which add a festive touch to the hotel atmosphere during holidays.

Travelers can unwind in the peaceful atmosphere of Clarion Inn & Suites, while the attractions of downtown Winona are a quick drive away. Find your comfort zone in Winona with a hotel that delivers great value—reserve now!

Guests headed to Winona will appreciate the enveloping comfort at MainStay Suites, where rooms start at $56.99, creating a clean, welcoming environment for relaxation. Enjoy the convenience of on-site ATM services at MainStay Suites, ensuring you have easy access to cash when needed.

At MainStay Suites, visitors can enjoy the calm surroundings, while knowing downtown Winona is still accessible for a day of city adventure. Stay effortlessly in Winona with accommodations that make relaxation simple—secure now!

For a restful and affordable stay, Econo Lodge offers inviting rooms with rates starting at $56.99, creating a soft and comfortable space ideal for travelers bound for Winona. Start your day with Econo Lodge's complimentary Easy Starts® breakfast, featuring a selection of quick and tasty options to get you on your way.

Unwind at Econo Lodge, where peaceful surroundings offer a relaxing stay and downtown Winona remains nearby for city exploration. Stay smart and enjoy added value for your Winona adventure—book your stay now!

Guests bound for Winona will appreciate the alluring accommodations at Suburban Studios Florence I-95, with rooms starting at $56.99, providing a warm, welcoming space for rest. Experience a stay that's both economical and satisfying, with rooms that provide necessary amenities for a comfortable visit.

Guests at Suburban Studios Florence I-95 can unwind in a tranquil setting, with the added benefit of downtown Winona being a convenient drive away. Book your Winona stay today and experience comfort without breaking the bank!

With affordable rooms starting at $54.99, Motel 6 Florence SC is ideal for guests visiting Winona, creating a reassuring and welcoming environment for relaxation. Take advantage of the spacious parking at Motel 6, accommodating vehicles of all sizes, from motorcycles to RVs.

Experience a serene retreat at Motel 6 Florence SC, where quiet surroundings offer relaxation and downtown Winona is just a drive away. Book a practical, inviting hotel for your Winona experience and enjoy more—secure now!

With rooms starting at $150.99, Country Inn & Suites by Radisson Florence SC provides inviting accommodations for guests traveling to Winona, creating a gentle, welcoming environment. Keep up with your fitness routine in the fully equipped gym at Country Inn & Suites, available to all guests during their stay.

For a peaceful stay, Country Inn & Suites by Radisson Florence SC offers a calm environment, while downtown Winona remains close enough for a day of sightseeing. Make the most of your Winona visit with a hotel that delivers exceptional value—reserve now!

At Park Inn by Radisson Florence SC, travelers to Winona will find budget-friendly rooms with rates starting at $128.99, creating a clean, welcoming environment perfect for rest. Enjoy the innovation of Radisson's fitness on demand, offering virtual classes and personal training sessions for a customized workout.

At Park Inn by Radisson Florence SC, guests can enjoy the quiet atmosphere while keeping downtown Winona within easy reach for a day of sightseeing. Plan your Winona getaway with a hotel that’s tailored for a perfect stay—secure now!

For an affordable and welcoming stay, Howard Johnson by Wyndham Florence offers budget-friendly rooms with rates from $79.99, creating a comfortable space perfect for guests bound for Winona. Relax knowing that Howard Johnson's family-friendly accommodations offer space, comfort, and conveniences for travelers of all ages.

With a scenic drive into downtown Winona, guests at Howard Johnson by Wyndham Florence can enjoy the city's best spots before returning to the calm of the hotel. Plan ahead and enjoy extra comfort at budget rates in Winona—book today!

With budget-conscious rooms starting at $118.99, La Quinta Inn & Suites by Wyndham Florence provides inviting accommodations for guests traveling to Winona, creating a clean, welcoming space. Experience attentive customer service at La Quinta, where staff are trained to handle your requests efficiently and with a smile.

With a relaxing drive into downtown Winona, guests at La Quinta Inn & Suites by Wyndham Florence can explore the city’s best spots before retreating to the peaceful surroundings of their stay. Discover a hotel that keeps your Winona visit affordable and comfortable—book your room now!

At Tru by Hilton Florence I-95, travelers headed to Winona will find inviting accommodations with rooms starting at $138.99, creating a clean and comfortable space. Enjoy the vibrant energy of Tru by Hilton’s color schemes, featuring bold and playful hues that reflect the brand’s youthful spirit.

Relax in the serene surroundings of Tru by Hilton Florence I-95, with the excitement of downtown Winona still a convenient drive away. Stay affordably and enjoy the best of Winona with a hotel that understands your needs—lock in today!

With affordable rooms from $68.99, Days Inn by Wyndham Florence / I-95 North provides charming comfort for travelers bound for Winona, creating a warm, inviting environment perfect for rest. Appreciate the modern amenities and services at Days Inn, designed to meet the needs of today's travelers.

For a restful escape, Days Inn by Wyndham Florence / I-95 North offers serene surroundings while keeping downtown Winona within reach for city exploration. Enjoy Winona adventures without the expense—book your inviting, cost-effective stay now!

For a comfortable and budget-friendly stay, Hampton Inn & Suites Florence North I-95 offers inviting rooms with rates beginning at $134.99, creating a friendly environment near Winona. Enjoy the simplicity of check-in and check-out at Hampton, designed to get you on your way quickly and hassle-free.

Travelers staying at Hampton Inn & Suites Florence North I-95 will appreciate the calm atmosphere, while downtown Winona is just a convenient drive away. Discover the smart way to stay in Winona with inviting and affordable lodging—reserve now!

With rates starting at $73.99, Sleep Inn Florence North is ideal for guests bound for Winona, providing delightful accommodations in a warm, inviting setting. Enjoy the convenience of Sleep Inn locations, strategically placed near airports, highways, and popular attractions.

Guests staying at Sleep Inn Florence North will appreciate the peaceful setting, with downtown Winona nearby for all their city adventures. Find budget-friendly lodging that makes your Winona trip unforgettable—book today!

For a budget-friendly and inviting stay near Winona, Comfort Suites Florence I-95 offers delightful accommodations with rates beginning at $141.99, creating a warm and comfortable environment. Stay energized with Comfort Suites' power breakfast options, featuring protein-rich and healthy choices to fuel your day.

From Comfort Suites Florence I-95, a relaxing drive brings guests into the heart of Winona, offering the perfect balance between city exploration and tranquility. Embrace the joy of Winona with a hotel that understands what you need—reserve now!

At Microtel Inn & Suites by Wyndham Florence, travelers to Winona will find welcoming rooms with rates beginning at $77.99, creating a warm, welcoming environment perfect for relaxation. Enjoy the peace of mind with Microtel's enhanced security features, ensuring a safe and worry-free stay for all guests.

Guests can unwind in the tranquil setting of Microtel Inn & Suites by Wyndham Florence, while the excitement of downtown Winona is just a drive away. Lock in an affordable, welcoming stay for your Winona visit—reserve your room now!

For those bound for Winona, Fairfield Inn & Suites by Marriott Florence I-20 offers serene, budget-friendly accommodations with rates from $179.99, creating a comfortable space perfect for relaxation. Discover the joy of traveling with family at Fairfield, where children stay free when using existing bedding in the room.

Guests staying at Fairfield Inn & Suites by Marriott Florence I-20 can unwind in a peaceful retreat, with downtown Winona still close enough for a day of city exploration. Choose accommodations that make your Winona adventure easy and enjoyable—reserve now!