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Top 24 Hotels In Wise, North Carolina 27563

Quality Inn Henderson I-85

112 Parham Road Henderson, NC

Guests traveling to Wise will find Quality Inn Henderson I-85 a comfortable, budget-friendly option, with rooms beginning at $97.99, creating a welcoming atmosphere perfect for rest. Wake up to a complimentary hot breakfast at Quality Inn, where a variety of delicious options await to kickstart your day.

Rest in the serene environment of Quality Inn Henderson I-85, with downtown Wise nearby for a blend of quiet and city excitement. Enjoy Wise travel made easy with practical, well-equipped lodging—book now!

  Call (855) 236-8982 to book with an agent.
  15.5 miles from Wise, NC 27563

Starting at

$97.99

per night

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Fairfield Inn & Suites by Marriott South Hill

150 Arnold Dr La Crosse, VA

For a budget-friendly stay, Fairfield Inn & Suites by Marriott South Hill offers inviting rooms with rates beginning at $169.99, creating a clean and comfortable space near Wise. Relax in the spaciousness of Fairfield's guest rooms, ideal for families or groups needing extra room to spread out and enjoy their stay.

Guests staying at Fairfield Inn & Suites by Marriott South Hill will love the quiet atmosphere, while downtown Wise remains close enough for a day of adventure. Relax and rejuvenate in Wise with accommodations that fit your budget perfectly—lock in today!

  Call (855) 239-4019 to book with an agent.
  15.7 miles from Wise, NC 27563

Starting at

$169.99

per night

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Microtel Inn & Suites by Wyndham South Hill

111 Arnold Drive La Crosse, VA

At Microtel Inn & Suites by Wyndham South Hill, travelers to Wise will find plush accommodations with rates beginning at $132.99, creating a warm, inviting space perfect for relaxation. Enjoy practical in-room amenities such as mini-fridges and microwaves in select suites at Microtel.

Guests at Microtel Inn & Suites by Wyndham South Hill will appreciate the calming environment, with downtown Wise still within reach for a day of city exploration. Stay relaxed and keep your budget intact while visiting Wise—reserve now!

  Call (855) 235-6136 to book with an agent.
  15.8 miles from Wise, NC 27563

Starting at

$132.99

per night

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Budget Host Inn

1727 North Garnett St Henderson, NC

With budget-friendly rooms beginning at $69.99, Budget Host Inn provides tucked away accommodations for travelers to Wise, creating a welcoming environment for rest. Stay in rooms that provide a perfect blend of comfort and convenience, designed to enhance your experience at an affordable rate.

From Budget Host Inn, guests can enjoy the peaceful retreat of the hotel, while downtown Wise remains easily accessible for sightseeing. Find the perfect base for exploring Wise with affordable, inviting accommodations—secure now!

  Call (855) 236-8982 to book with an agent.
  15.8 miles from Wise, NC 27563

Starting at

$69.99

per night

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Hampton Inn South Hill

200 Thompson Rd South Hill, VA

For an affordable stay near Wise, Hampton Inn South Hill offers inviting accommodations with rooms starting at $113.99, creating a clean and comfortable space. Swim any season in Hampton’s indoor pools, providing a warm and welcoming place to relax, regardless of the weather.

Relax in the serene surroundings of Hampton Inn South Hill, with downtown Wise remaining within easy reach for a day of exploration. Discover how great your Wise visit can be with thoughtfully priced lodging—lock in today!

  Call (855) 234-7135 to book with an agent.
  16.0 miles from Wise, NC 27563

Starting at

$113.99

per night

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Quality Inn South Hill I-85

918 East Atlantic St South Hill, VA

For budget-savvy travelers, Quality Inn South Hill I-85 provides peaceful accommodations with rates beginning at $65.99, creating a clean and comfortable space near Wise. Relax in Quality Inn's sauna or steam rooms, available at select locations for a soothing and detoxifying experience.

At Quality Inn South Hill I-85, the quiet atmosphere offers a restful stay, with the added convenience of downtown Wise being nearby for sightseeing. Enjoy a memorable Wise experience with a hotel that makes every moment count—reserve now!

  Call (855) 234-2997 to book with an agent.
  16.0 miles from Wise, NC 27563

Starting at

$65.99

per night

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Comfort Inn & Suites South Hill I-85

250 Thompson Street South Hill, VA

At Comfort Inn & Suites South Hill I-85, travelers headed to Wise will find inviting accommodations with rooms starting at $109.99, creating a clean and comfortable space. Keep cool and comfortable year-round with air-conditioned rooms, ensuring a pleasant stay regardless of the weather.

For a serene stay, Comfort Inn & Suites South Hill I-85 provides calm surroundings, with the excitement of downtown Wise still a short drive away. Explore Wise knowing your accommodations prioritize both comfort and savings—lock in today!

  Call (855) 239-5277 to book with an agent.
  16.1 miles from Wise, NC 27563

Starting at

$109.99

per night

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Red Roof PLUS+ Henderson

200 Simmons Street Henderson, NC

With rates beginning at $89.49, Red Roof PLUS+ Henderson provides budget-friendly accommodations for travelers visiting Wise, creating a warm and inviting environment. Find value in accommodations that offer a bit more comfort and convenience, ensuring a pleasant and economical stay.

At Red Roof PLUS+ Henderson, guests can enjoy the serene surroundings, knowing that downtown Wise remains within reach for a day of adventure. Find exceptional value and extra amenities on your Wise adventure—reserve your hotel room now!

  Call (855) 234-2997 to book with an agent.
  18.3 miles from Wise, NC 27563

Starting at

$89.49

per night

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Hampton Inn Henderson

385 Ruin Creek Rd Henderson, NC

With budget-conscious rooms beginning at $142.99, Hampton Inn Henderson provides inviting accommodations for travelers visiting Wise, creating a tucked away, comfortable environment. Treat yourself at Hampton’s vending machines, conveniently located for a quick snack or drink without leaving the hotel.

For those seeking quiet, Hampton Inn Henderson offers a serene retreat while keeping downtown Wise easily accessible for city exploration. Enjoy your Wise adventure with a hotel that’s all about great value—lock in today!

  Call (855) 235-0725 to book with an agent.
  18.5 miles from Wise, NC 27563

Starting at

$142.99

per night

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Holiday Inn Express & Suites South Hill an IHG Hotel

1840 North Mecklenburg Avenue South Hill, VA

With rates beginning at $149.00, Holiday Inn Express & Suites South Hill an IHG Hotel provides budget-friendly comfort for travelers bound for Wise, creating a clean, inviting space. Stay cool and refreshed with Holiday Inn Express's air-conditioned rooms, ensuring a comfortable environment regardless of the weather.

Guests at Holiday Inn Express & Suites South Hill an IHG Hotel can enjoy a serene escape, with downtown Wise remaining accessible for city exploration. Step into Wise comfort with inviting, cost-effective lodging—book your room now!

  Call (855) 236-8982 to book with an agent.
  18.5 miles from Wise, NC 27563

Starting at

$149.00

per night

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Baymont by Wyndham Henderson Oxford

400 North Cooper Dr Henderson, NC

With rates beginning at $95.99, Baymont by Wyndham Henderson Oxford is ideal for guests visiting Wise, offering easygoing accommodations in a welcoming, clean environment. Relax on Baymont by Wyndham’s outdoor patios, offering a pleasant environment to unwind after a busy day.

For a quiet stay, Baymont by Wyndham Henderson Oxford offers serene surroundings with the convenience of downtown Wise still a short drive away. Embrace the joy of Wise with a hotel that understands what you need—reserve now!

  Call (855) 233-7850 to book with an agent.
  18.6 miles from Wise, NC 27563

Starting at

$95.99

per night

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Sleep Inn Henderson I-85

18 Market St Henderson, NC

For those headed to Wise, Sleep Inn Henderson I-85 offers budget-friendly comfort with rooms starting at $97.99, creating a clean, welcoming environment perfect for unwinding. Take a moment to unwind in Sleep Inn's outdoor seating areas, offering a quiet setting for relaxation or casual meetings.

Guests at Sleep Inn Henderson I-85 will appreciate the calm environment, with the excitement of downtown Wise just a short drive away. Take advantage of thoughtful amenities and affordable rates for your Wise trip—book today!

  Call (855) 234-2997 to book with an agent.
  19.2 miles from Wise, NC 27563

Starting at

$97.99

per night

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Quality Inn on the Lake Clarksville Boydton

101 Virginia Ave Clarksville, VA

With budget-friendly rooms from $154.99, Quality Inn on the Lake Clarksville Boydton provides inviting comfort for travelers visiting Wise, creating a warm, welcoming space. Experience attentive service with Quality Inn's concierge team, ready to assist with reservations, transportation, and personal requests.

Unwind at Quality Inn on the Lake Clarksville Boydton, a peaceful retreat offering both relaxation and the convenience of Wise just a short drive away. Enjoy the perfect mix of affordability and comfort during your Wise stay—reserve today!

  Call (855) 233-0132 to book with an agent.
  23.3 miles from Wise, NC 27563

Starting at

$154.99

per night

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Clarion Pointe on the lake Clarksville South Hill West

103 2nd St Clarksville, VA

With rates beginning at $147.99, Clarion Pointe on the lake Clarksville South Hill West is a practical choice for guests visiting Wise, providing a cozy-like and inviting space ideal for relaxation. Experience a blend of comfort and value in rooms that offer additional amenities to make your stay enjoyable and efficient.

Enjoy the best of both relaxation and convenience at Clarion Pointe on the lake Clarksville South Hill West, where guests can unwind and still reach Wise with ease. Enjoy your Wise visit to the fullest with a hotel that delivers cost-effective comfort—secure now!

  Call (855) 234-5074 to book with an agent.
  23.4 miles from Wise, NC 27563

Starting at

$147.99

per night

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Days Inn&Suites by Wyndham Oxford

913 Martin Luther King Jr Ave Oxford, NC

At Days Inn&Suites by Wyndham Oxford, travelers to Wise can enjoy snug comfort with rooms beginning at $104.99, creating a welcoming environment ideal for a restful stay. Discover the flexibility of our room options, catering to everything from business trips to family vacations.

Guests seeking both rest and exploration will love Days Inn&Suites by Wyndham Oxford, where peaceful lodgings are matched with easy access to Wise. Choose a Wise hotel that keeps you comfortable and your budget intact—reserve now!

  Call (855) 234-7135 to book with an agent.
  26.2 miles from Wise, NC 27563

Starting at

$104.99

per night

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Comfort Inn & Suites Oxford South

1000 Martin Luther King Jr. Ave Oxford, NC

For budget-savvy travelers headed to Wise, Comfort Inn & Suites Oxford South offers intimate comfort with rooms starting at $111.99, creating a clean, inviting environment. Stay connected with Comfort Inn's free high-speed Wi-Fi, making it easy to work or keep in touch while on the road.

Escape the urban bustle at Comfort Inn & Suites Oxford South, where spacious accommodations offer comfort and quick access to Wise's sights. Choose a hotel that adds value to your Wise experience—reserve your stay now!

  Call (855) 235-0725 to book with an agent.
  26.3 miles from Wise, NC 27563

Starting at

$111.99

per night

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Days Inn by Wyndham Louisburg

201 Sandalwood Ave Louisburg, NC

Guests visiting Wise will find enchanting comfort at Days Inn by Wyndham Louisburg, where rooms start at $96.00, providing a clean and welcoming environment ideal for a restful stay. Take advantage of Days Inn's pet-friendly policy, allowing you to bring your furry friends along on your journey.

At Days Inn by Wyndham Louisburg, you'll find a peaceful retreat with the added benefit of being close to Wise for exploration. Make your Wise experience both cost-effective and comfortable—secure your stay today!

  Call (855) 234-5074 to book with an agent.
  27.8 miles from Wise, NC 27563

Starting at

$96.00

per night

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Fairfax Motel

1135 East 10th Street Roanoke Rapids, NC

For budget-savvy travelers to Wise, Fairfax Motel offers inviting accommodations with rooms from $61.95, creating a warm, comfortable environment for rest. Enjoy reliable comfort in rooms that provide everything you need for a worry-free visit at an economical price.

Guests seeking both rest and excitement will love Fairfax Motel, where peaceful lodgings are paired with proximity to Wise. Book now and enjoy a relaxing, cost-effective Wise adventure—reserve your room!

  Call (855) 239-4019 to book with an agent.
  29.3 miles from Wise, NC 27563

Starting at

$61.95

per night

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SureStay Plus Hotel by Best Western Roanoke Rapids I-95

136 Sheraton Dr Roanoke Rapids, NC

For a restful stay, SureStay Plus Hotel by Best Western Roanoke Rapids I-95 offers inviting accommodations with rooms starting at $79.49, creating a clean, welcoming environment perfect for travelers. Experience Best Western's family rooms, designed with extra space and amenities to comfortably accommodate all family members.

Unwind in comfort at SureStay Plus Hotel by Best Western Roanoke Rapids I-95, where guests can rest in quiet surroundings and still enjoy the convenience of Wise. Embrace the best of Wise with a welcoming, cost-effective hotel—book your stay today!

  Call (855) 233-0132 to book with an agent.
  29.7 miles from Wise, NC 27563

Starting at

$79.49

per night

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Quality Inn Roanoke near Lake Gaston

1914 Julian R Allsbrook Hwy Roanoke Rapids, NC

With rates beginning at $83.99, Quality Inn Roanoke near Lake Gaston is a smart choice for travelers to Wise, creating a quiet space perfect for rest and relaxation. Indulge in a luxury experience with Quality Inn's suite upgrades, featuring additional space and premium amenities.

At Quality Inn Roanoke near Lake Gaston, guests are treated to restful accommodations with the advantage of being close to Wise's top destinations. Get the rest and comfort you deserve while exploring Wise—secure your hotel room now!

  Call (855) 235-0725 to book with an agent.
  29.8 miles from Wise, NC 27563

Starting at

$83.99

per night

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Baymont by Wyndham Roanoke Rapids

101 South Old Farm Road Roanoke Rapids, NC

For an inviting stay near Wise, Baymont by Wyndham Roanoke Rapids offers restful accommodations with rooms starting at $69.99, creating a clean and comfortable environment for rest. Stay connected with free high-speed Wi-Fi at Baymont by Wyndham, available throughout the hotel for your convenience.

Unwind in style at Baymont by Wyndham Roanoke Rapids, where guests can enjoy the calm atmosphere and still explore Wise at their leisure. Stay refreshed and on budget in Wise with thoughtfully designed accommodations—secure today!

  Call (855) 236-8982 to book with an agent.
  29.8 miles from Wise, NC 27563

Starting at

$69.99

per night

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Country Inn & Suites by Radisson Roanoke Rapids NC

101 Hampton Boulevard Roanoke Rapids, NC

With rates from $107.99, Country Inn & Suites by Radisson Roanoke Rapids NC provides affordable comfort for guests bound for Wise, creating a enveloping and welcoming atmosphere for relaxation. Unwind in the hotel’s indoor or outdoor pool, a perfect way to relax after a day of travel or meetings at Country Inn & Suites.

Find your sanctuary at Country Inn & Suites by Radisson Roanoke Rapids NC, a restful spot positioned just a short drive from the lively streets of Wise. Stay in style and save while visiting Wise with inviting, budget-conscious lodging—lock in today!

  Call (855) 235-6136 to book with an agent.
  30.0 miles from Wise, NC 27563

Starting at

$107.99

per night

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Hilton Garden Inn Roanoke Rapids

111 Carolina Crossroads Pkwy Roanoke Rapids, NC

Choose Hilton Garden Inn Roanoke Rapids when traveling to Wise, where comfortable accommodations provide a welcoming experience, with affordable rates starting from $129.99. Take in the thoughtful design of Hilton Garden Inn's guest rooms, combining comfort with functionality for a restful stay.

Experience the best of both worlds at Hilton Garden Inn Roanoke Rapids, where relaxation meets the convenience of being close to Wise. Enjoy a Wise visit that’s as effortless as it is enjoyable with welcoming accommodations—book today!

  Call (855) 233-0132 to book with an agent.
  30.0 miles from Wise, NC 27563

Starting at

$129.99

per night

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Red Roof Inn Roanoke Rapids

1911 Julian R Allsbrook Hwy Roanoke Rapids, NC

With affordable rooms starting at $86.00, Red Roof Inn Roanoke Rapids provides budget-conscious comfort for guests visiting Wise, creating a welcoming and relaxing space. Experience the convenience of Red Roof Inn's on-site amenities, ensuring you have everything you need for a pleasant stay.

Relax in the spacious setting of Red Roof Inn Roanoke Rapids, where guests can unwind and still have easy access to Wise. Stay relaxed and save more while exploring Wise—reserve your hotel today!

  Call (855) 235-0725 to book with an agent.
  30.1 miles from Wise, NC 27563

Starting at

$86.00

per night

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